Rattus norvegicus

67 known processes

Numbl

numb homolog (Drosophila)-like

Numbl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex subunit organization GO:0071822 302 0.073
macromolecular complex subunit organization GO:0043933 339 0.058
cellular component assembly GO:0022607 360 0.054
cellular response to oxygen containing compound GO:1901701 386 0.052
neuron differentiation GO:0030182 368 0.050
regulation of cellular component organization GO:0051128 368 0.048
cell projection organization GO:0030030 302 0.047
organelle organization GO:0006996 266 0.044
protein complex biogenesis GO:0070271 263 0.043
positive regulation of cell communication GO:0010647 271 0.042
macromolecule localization GO:0033036 252 0.039
Fly
protein complex assembly GO:0006461 263 0.039
macromolecular complex assembly GO:0065003 273 0.036
positive regulation of cell differentiation GO:0045597 217 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
regulation of molecular function GO:0065009 398 0.034
regulation of nervous system development GO:0051960 264 0.034
regulation of protein metabolic process GO:0051246 289 0.034
cell cell signaling GO:0007267 335 0.032
intracellular signal transduction GO:0035556 314 0.032
neuron development GO:0048666 286 0.032
cell morphogenesis GO:0000902 142 0.032
transmembrane transport GO:0055085 412 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
synaptic growth at neuromuscular junction GO:0051124 1 0.031
programmed cell death GO:0012501 392 0.030
regulation of cell differentiation GO:0045595 320 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
positive regulation of response to stimulus GO:0048584 285 0.029
cell part morphogenesis GO:0032990 123 0.028
multicellular organism reproduction GO:0032504 233 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
positive regulation of developmental process GO:0051094 283 0.028
cellular response to stress GO:0033554 269 0.027
regulation of nucleotide metabolic process GO:0006140 117 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
cellular component biogenesis GO:0044085 368 0.027
regulation of signal transduction GO:0009966 318 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
regulation of cell development GO:0060284 263 0.026
protein phosphorylation GO:0006468 345 0.026
cellular metal ion homeostasis GO:0006875 172 0.025
organic acid metabolic process GO:0006082 292 0.025
metal ion transport GO:0030001 289 0.025
cellular amine metabolic process GO:0044106 38 0.025
single organism catabolic process GO:0044712 283 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.025
behavior GO:0007610 205 0.025
single organism organelle organization GO:1902589 180 0.024
neuron projection development GO:0031175 273 0.024
negative regulation of cell communication GO:0010648 158 0.024
regulation of protein modification process GO:0031399 194 0.024
positive regulation of signaling GO:0023056 270 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
muscle structure development GO:0061061 87 0.023
Fly
amine metabolic process GO:0009308 38 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
intracellular transport GO:0046907 185 0.023
regulation of system process GO:0044057 208 0.023
cellular ketone metabolic process GO:0042180 51 0.023
response to extracellular stimulus GO:0009991 380 0.023
protein oligomerization GO:0051259 191 0.023
response to oxygen levels GO:0070482 265 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
nucleic acid templated transcription GO:0097659 379 0.022
rna biosynthetic process GO:0032774 380 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
response to wounding GO:0009611 254 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of apoptotic process GO:0042981 335 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
organophosphate metabolic process GO:0019637 370 0.021
negative regulation of signaling GO:0023057 157 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
rna metabolic process GO:0016070 406 0.021
regulation of rna metabolic process GO:0051252 391 0.021
central nervous system development GO:0007417 311 0.021
Mouse
reproduction GO:0000003 245 0.021
neurological system process GO:0050877 219 0.021
negative regulation of metabolic process GO:0009892 331 0.021
regulation of neuron differentiation GO:0045664 208 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
response to acid chemical GO:0001101 222 0.020
apoptotic process GO:0006915 381 0.020
synapse organization GO:0050808 46 0.020
reproductive process GO:0022414 372 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
transcription dna templated GO:0006351 377 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
chemical homeostasis GO:0048878 292 0.019
synaptic transmission GO:0007268 235 0.019
homeostatic process GO:0042592 331 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
single organism intracellular transport GO:1902582 166 0.019
ras protein signal transduction GO:0007265 29 0.019
divalent inorganic cation transport GO:0072511 134 0.019
multi organism reproductive process GO:0044703 262 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
secretion GO:0046903 307 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
regulation of transcription dna templated GO:0006355 374 0.018
response to nutrient levels GO:0031667 370 0.018
cellular homeostasis GO:0019725 252 0.018
cellular macromolecule localization GO:0070727 122 0.018
cytoplasmic transport GO:0016482 115 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of programmed cell death GO:0043067 341 0.018
response to ketone GO:1901654 182 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
developmental growth GO:0048589 100 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
oxoacid metabolic process GO:0043436 290 0.017
cellular cation homeostasis GO:0030003 180 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
positive regulation of signal transduction GO:0009967 175 0.017
cation homeostasis GO:0055080 195 0.017
cell projection morphogenesis GO:0048858 123 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
regulation of neuron projection development GO:0010975 161 0.017
dendrite development GO:0016358 72 0.017
regulation of phosphorylation GO:0042325 248 0.017
positive regulation of molecular function GO:0044093 230 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
establishment of protein localization GO:0045184 141 0.017
regulation of synaptic transmission GO:0050804 141 0.017
cellular protein localization GO:0034613 122 0.017
regulation of response to stress GO:0080134 126 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
metal ion homeostasis GO:0055065 186 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
ion homeostasis GO:0050801 212 0.016
nucleotide metabolic process GO:0009117 279 0.016
learning or memory GO:0007611 90 0.016
embryonic skeletal system morphogenesis GO:0048704 3 0.016
tissue development GO:0009888 252 0.016
Fly
regulation of multicellular organismal development GO:2000026 376 0.016
single organism reproductive process GO:0044702 297 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
positive regulation of protein modification process GO:0031401 142 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
cellular chemical homeostasis GO:0055082 247 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
catabolic process GO:0009056 351 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
gastrulation GO:0007369 2 0.016
negative regulation of cell death GO:0060548 229 0.016
localization of cell GO:0051674 202 0.016
Fly
brain development GO:0007420 247 0.016
Mouse
protein localization GO:0008104 191 0.015
Fly
cellular catabolic process GO:0044248 295 0.015
purine containing compound metabolic process GO:0072521 253 0.015
rhythmic process GO:0048511 156 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
circulatory system process GO:0003013 183 0.015
regulation of anatomical structure size GO:0090066 135 0.015
response to nutrient GO:0007584 248 0.015
cytoskeleton organization GO:0007010 111 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of gene expression GO:0010628 244 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
protein transport GO:0015031 132 0.015
cation transport GO:0006812 382 0.015
response to peptide hormone GO:0043434 278 0.015
response to carbohydrate GO:0009743 183 0.015
response to decreased oxygen levels GO:0036293 237 0.015
neuron neuron synaptic transmission GO:0007270 60 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
regulation of cellular localization GO:0060341 263 0.015
nucleoside metabolic process GO:0009116 179 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.014
negative regulation of developmental process GO:0051093 125 0.014
aging GO:0007568 241 0.014
organic substance catabolic process GO:1901575 316 0.014
response to reactive oxygen species GO:0000302 120 0.014
calcium ion transport GO:0006816 131 0.014
positive regulation of cell development GO:0010720 176 0.014
neuron projection morphogenesis GO:0048812 122 0.014
secretion by cell GO:0032940 248 0.014
response to inorganic substance GO:0010035 377 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
regulation of membrane potential GO:0042391 110 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
locomotion GO:0040011 237 0.014
Fly
peptidyl amino acid modification GO:0018193 126 0.014
aromatic compound catabolic process GO:0019439 168 0.014
cellular component morphogenesis GO:0032989 155 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
vesicle mediated transport GO:0016192 181 0.013
Fly
growth GO:0040007 165 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
axon development GO:0061564 96 0.013
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.013
action potential GO:0001508 54 0.013
embryonic skeletal system development GO:0048706 3 0.013
sequestering of metal ion GO:0051238 9 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
regulation of catalytic activity GO:0050790 304 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
defense response GO:0006952 194 0.013
regulation of cell proliferation GO:0042127 359 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
positive regulation of nervous system development GO:0051962 178 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
regulation of fat cell differentiation GO:0045598 3 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
sequestering of calcium ion GO:0051208 8 0.013
negative regulation of gene expression GO:0010629 199 0.013
cell cycle GO:0007049 101 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
response to mechanical stimulus GO:0009612 134 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
regulation of cellular response to stress GO:0080135 49 0.013
cell type specific apoptotic process GO:0097285 134 0.013
rho protein signal transduction GO:0007266 11 0.013
calcium ion homeostasis GO:0055074 162 0.013
regulation of secretion GO:0051046 224 0.012
cognition GO:0050890 92 0.012
response to corticosteroid GO:0031960 235 0.012
regeneration GO:0031099 163 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
divalent metal ion transport GO:0070838 132 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
response to vitamin GO:0033273 131 0.012
heterocycle catabolic process GO:0046700 167 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
blood circulation GO:0008015 183 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
positive regulation of cell death GO:0010942 184 0.012
regulation of cell projection organization GO:0031344 175 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
response to ethanol GO:0045471 162 0.012
regulation of ion transport GO:0043269 245 0.012
adult locomotory behavior GO:0008344 4 0.012
muscle tissue development GO:0060537 58 0.012
salivary gland development GO:0007431 3 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
sexual reproduction GO:0019953 148 0.012
response to metal ion GO:0010038 253 0.012
response to hypoxia GO:0001666 231 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
muscle system process GO:0003012 115 0.012
spindle organization GO:0007051 2 0.012
wound healing GO:0042060 122 0.011
negative regulation of transport GO:0051051 136 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
mitotic spindle organization GO:0007052 2 0.011
response to growth factor GO:0070848 189 0.011
regulation of response to external stimulus GO:0032101 106 0.011
ion transmembrane transport GO:0034220 365 0.011
cell growth GO:0016049 104 0.011
response to alkaloid GO:0043279 132 0.011
positive regulation of ion transport GO:0043270 94 0.011
regulation of kinase activity GO:0043549 117 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
response to axon injury GO:0048678 59 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
chemosensory behavior GO:0007635 2 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cation transmembrane transport GO:0098655 263 0.011
positive regulation of transport GO:0051050 245 0.011
Fly
proteolysis GO:0006508 175 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
eye morphogenesis GO:0048592 4 0.011
negative regulation of molecular function GO:0044092 133 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
multicellular organismal signaling GO:0035637 44 0.011
signal release GO:0023061 145 0.011
nucleoside catabolic process GO:0009164 126 0.010
regulation of nucleic acid templated transcription GO:1903506 380 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
axis specification GO:0009798 4 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
regulation of metal ion transport GO:0010959 118 0.010
skeletal muscle organ development GO:0060538 33 0.010
membrane organization GO:0061024 94 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
muscle cell differentiation GO:0042692 52 0.010
Fly
regulation of homeostatic process GO:0032844 101 0.010
gamete generation GO:0007276 124 0.010
head development GO:0060322 247 0.010
Mouse
regulation of neuron death GO:1901214 115 0.010
olfactory behavior GO:0042048 2 0.010
regulation of protein kinase activity GO:0045859 105 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
positive regulation of synaptic transmission GO:0050806 62 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
regulation of organelle organization GO:0033043 80 0.010
regulation of growth GO:0040008 105 0.010
purine containing compound catabolic process GO:0072523 138 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
axonogenesis GO:0007409 71 0.010
Mouse
response to lipopolysaccharide GO:0032496 191 0.010
mapk cascade GO:0000165 140 0.010
single organism behavior GO:0044708 130 0.010

Numbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
musculoskeletal system disease DOID:17 0 0.011