Rattus norvegicus

8 known processes

Hmox2

heme oxygenase (decycling) 2

(Aliases: Ho-2)

Hmox2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 351 0.135
Rat
organic substance catabolic process GO:1901575 316 0.084
Rat
cellular catabolic process GO:0044248 295 0.080
Rat
regulation of molecular function GO:0065009 398 0.072
Rat
intracellular signal transduction GO:0035556 314 0.069
Rat
organelle organization GO:0006996 266 0.059
oxoacid metabolic process GO:0043436 290 0.058
single organism catabolic process GO:0044712 283 0.057
Rat
regulation of catalytic activity GO:0050790 304 0.056
intracellular transport GO:0046907 185 0.054
Rat
organophosphate metabolic process GO:0019637 370 0.053
protein phosphorylation GO:0006468 345 0.051
macromolecule localization GO:0033036 252 0.050
positive regulation of biosynthetic process GO:0009891 319 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.047
Rat
cellular response to stress GO:0033554 269 0.047
Rat
organic acid metabolic process GO:0006082 292 0.045
rna metabolic process GO:0016070 406 0.045
Rat
regulation of ion transport GO:0043269 245 0.044
programmed cell death GO:0012501 392 0.044
Rat
positive regulation of cell communication GO:0010647 271 0.044
positive regulation of molecular function GO:0044093 230 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
protein complex biogenesis GO:0070271 263 0.042
response to nutrient levels GO:0031667 370 0.042
Rat
apoptotic process GO:0006915 381 0.041
Rat
response to metal ion GO:0010038 253 0.040
cation transport GO:0006812 382 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
transcription dna templated GO:0006351 377 0.039
Rat
macromolecular complex subunit organization GO:0043933 339 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.038
Rat
regulation of programmed cell death GO:0043067 341 0.038
Rat
reproductive process GO:0022414 372 0.037
nucleic acid templated transcription GO:0097659 379 0.037
Rat
positive regulation of transport GO:0051050 245 0.037
cellular component assembly GO:0022607 360 0.037
cellular amino acid metabolic process GO:0006520 107 0.036
regulation of transcription dna templated GO:0006355 374 0.036
Rat
regulation of rna biosynthetic process GO:2001141 381 0.036
Rat
establishment of protein localization GO:0045184 141 0.035
secretion GO:0046903 307 0.034
Rat
regulation of signal transduction GO:0009966 318 0.033
cellular lipid metabolic process GO:0044255 208 0.033
regulation of protein phosphorylation GO:0001932 183 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
multi organism reproductive process GO:0044703 262 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
Rat
regulation of cellular component organization GO:0051128 368 0.032
protein transport GO:0015031 132 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
central nervous system development GO:0007417 311 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
rna biosynthetic process GO:0032774 380 0.031
Rat
single organism biosynthetic process GO:0044711 342 0.030
single organism reproductive process GO:0044702 297 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
response to inorganic substance GO:0010035 377 0.030
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.030
ribose phosphate metabolic process GO:0019693 235 0.030
vesicle mediated transport GO:0016192 181 0.029
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.029
cell projection organization GO:0030030 302 0.029
purine ribonucleotide catabolic process GO:0009154 136 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
cellular component biogenesis GO:0044085 368 0.028
regulation of cell development GO:0060284 263 0.028
homeostatic process GO:0042592 331 0.028
synaptic transmission GO:0007268 235 0.028
neuron differentiation GO:0030182 368 0.028
regulation of protein modification process GO:0031399 194 0.027
head development GO:0060322 247 0.027
regulation of rna metabolic process GO:0051252 391 0.027
Rat
ion transmembrane transport GO:0034220 365 0.026
protein localization GO:0008104 191 0.026
reproduction GO:0000003 245 0.026
cellular ketone metabolic process GO:0042180 51 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
Rat
calcium ion transport GO:0006816 131 0.026
organonitrogen compound biosynthetic process GO:1901566 167 0.025
purine containing compound metabolic process GO:0072521 253 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
positive regulation of signaling GO:0023056 270 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
single organism intracellular transport GO:1902582 166 0.025
Rat
protein oligomerization GO:0051259 191 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
small molecule biosynthetic process GO:0044283 124 0.025
nucleotide metabolic process GO:0009117 279 0.024
metal ion transport GO:0030001 289 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.024
Rat
regulation of protein metabolic process GO:0051246 289 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
cellular macromolecule localization GO:0070727 122 0.024
intracellular protein transport GO:0006886 79 0.024
protein complex subunit organization GO:0071822 302 0.024
neurological system process GO:0050877 219 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
cellular amine metabolic process GO:0044106 38 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
Rat
negative regulation of metabolic process GO:0009892 331 0.023
regulation of neurogenesis GO:0050767 247 0.023
cation transmembrane transport GO:0098655 263 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
carbohydrate derivative catabolic process GO:1901136 147 0.022
nitrogen compound transport GO:0071705 229 0.022
amine metabolic process GO:0009308 38 0.022
regulation of nervous system development GO:0051960 264 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
neuron development GO:0048666 286 0.022
lipid metabolic process GO:0006629 283 0.022
single organism organelle organization GO:1902589 180 0.022
cellular chemical homeostasis GO:0055082 247 0.022
macromolecular complex assembly GO:0065003 273 0.022
regulation of apoptotic process GO:0042981 335 0.021
Rat
chemical homeostasis GO:0048878 292 0.021
regulation of cellular localization GO:0060341 263 0.021
Rat
regulation of neuron differentiation GO:0045664 208 0.021
regulation of phosphorylation GO:0042325 248 0.021
inorganic cation transmembrane transport GO:0098662 202 0.021
heterocycle catabolic process GO:0046700 167 0.021
Rat
aging GO:0007568 241 0.021
lipid biosynthetic process GO:0008610 128 0.020
multicellular organism reproduction GO:0032504 233 0.020
regulation of cell differentiation GO:0045595 320 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
cell cell signaling GO:0007267 335 0.020
ion homeostasis GO:0050801 212 0.020
carboxylic acid biosynthetic process GO:0046394 83 0.020
regulation of cell projection organization GO:0031344 175 0.020
purine nucleotide catabolic process GO:0006195 136 0.020
regulation of cell proliferation GO:0042127 359 0.020
Rat
transmembrane transport GO:0055085 412 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
regulation of hydrolase activity GO:0051336 143 0.020
response to extracellular stimulus GO:0009991 380 0.020
Rat
cellular response to oxygen containing compound GO:1901701 386 0.019
response to corticosteroid GO:0031960 235 0.019
negative regulation of molecular function GO:0044092 133 0.019
Rat
inorganic ion transmembrane transport GO:0098660 229 0.019
response to ketone GO:1901654 182 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
neuron death GO:0070997 127 0.019
Rat
divalent inorganic cation transport GO:0072511 134 0.019
neuron projection development GO:0031175 273 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of synaptic transmission GO:0050804 141 0.019
regulation of neuron death GO:1901214 115 0.019
Rat
organophosphate biosynthetic process GO:0090407 143 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
purine containing compound catabolic process GO:0072523 138 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
response to oxidative stress GO:0006979 186 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
response to biotic stimulus GO:0009607 226 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
regulation of secretion GO:0051046 224 0.018
Rat
positive regulation of gene expression GO:0010628 244 0.018
cell adhesion GO:0007155 110 0.018
brain development GO:0007420 247 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
organophosphate catabolic process GO:0046434 148 0.018
proteolysis GO:0006508 175 0.017
response to peptide GO:1901652 292 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
alcohol metabolic process GO:0006066 77 0.017
response to glucocorticoid GO:0051384 223 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
positive regulation of secretion GO:0051047 140 0.017
regulation of protein localization GO:0032880 81 0.017
positive regulation of cell death GO:0010942 184 0.017
response to peptide hormone GO:0043434 278 0.017
immune response GO:0006955 104 0.017
Rat
cellular homeostasis GO:0019725 252 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of system process GO:0044057 208 0.016
negative regulation of gene expression GO:0010629 199 0.016
response to oxygen levels GO:0070482 265 0.016
Rat
regulation of secretion by cell GO:1903530 208 0.016
Rat
positive regulation of cell development GO:0010720 176 0.016
oxidation reduction process GO:0055114 304 0.016
regulation of purine nucleotide catabolic process GO:0033121 65 0.016
regulation of catabolic process GO:0009894 113 0.016
defense response GO:0006952 194 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
salivary gland development GO:0007431 3 0.016
divalent metal ion transport GO:0070838 132 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
Rat
developmental process involved in reproduction GO:0003006 159 0.015
heart morphogenesis GO:0003007 3 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
regulation of membrane potential GO:0042391 110 0.015
axis specification GO:0009798 4 0.015
response to bacterium GO:0009617 200 0.015
tissue development GO:0009888 252 0.015
protein targeting GO:0006605 61 0.015
sexual reproduction GO:0019953 148 0.015
negative regulation of innate immune response GO:0045824 4 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
Rat
organic acid biosynthetic process GO:0016053 83 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
negative regulation of cell death GO:0060548 229 0.015
Rat
cellular response to oxidative stress GO:0034599 76 0.015
Rat
membrane organization GO:0061024 94 0.015
cellular protein localization GO:0034613 122 0.015
protein maturation GO:0051604 68 0.015
negative regulation of signaling GO:0023057 157 0.014
regulation of metal ion transport GO:0010959 118 0.014
response to growth factor GO:0070848 189 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
Rat
regulation of body fluid levels GO:0050878 90 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of developmental process GO:0051094 283 0.014
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
single organism membrane organization GO:0044802 74 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
Rat
regulation of neuron projection development GO:0010975 161 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular component morphogenesis GO:0032989 155 0.014
nucleotide catabolic process GO:0009166 139 0.014
ras protein signal transduction GO:0007265 29 0.014
cell projection morphogenesis GO:0048858 123 0.014
dna metabolic process GO:0006259 96 0.014
response to carbohydrate GO:0009743 183 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
regulation of protein kinase activity GO:0045859 105 0.014
negative regulation of transport GO:0051051 136 0.014
Rat
negative regulation of programmed cell death GO:0043069 183 0.013
Rat
cellular component movement GO:0006928 248 0.013
regulation of kinase activity GO:0043549 117 0.013
response to alkaloid GO:0043279 132 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
female pregnancy GO:0007565 122 0.013
reproductive system development GO:0061458 128 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
Rat
cation homeostasis GO:0055080 195 0.013
single organism cellular localization GO:1902580 102 0.013
Rat
purine nucleoside catabolic process GO:0006152 124 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
Rat
cytoplasmic transport GO:0016482 115 0.013
metal ion homeostasis GO:0055065 186 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
regulation of transferase activity GO:0051338 123 0.013
response to decreased oxygen levels GO:0036293 237 0.013
Rat
nucleoside triphosphate catabolic process GO:0009143 123 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
regulation of anatomical structure size GO:0090066 135 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
phospholipid metabolic process GO:0006644 61 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
response to ethanol GO:0045471 162 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
localization of cell GO:0051674 202 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
regulation of calcium ion transport GO:0051924 77 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
actin filament based process GO:0030029 86 0.012
regulation of protein transport GO:0051223 68 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
response to wounding GO:0009611 254 0.012
protein complex assembly GO:0006461 263 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
response to external biotic stimulus GO:0043207 221 0.012
organic anion transport GO:0015711 132 0.012
protein homooligomerization GO:0051260 91 0.012
synaptic vesicle localization GO:0097479 24 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
anterior posterior pattern specification GO:0009952 1 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
positive regulation of protein modification process GO:0031401 142 0.012
response to radiation GO:0009314 137 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
nucleoside metabolic process GO:0009116 179 0.012
regulation of response to stress GO:0080134 126 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of proteolysis GO:0030162 66 0.011
adult locomotory behavior GO:0008344 4 0.011
cellular cation homeostasis GO:0030003 180 0.011
cytoskeleton organization GO:0007010 111 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
negative regulation of cell development GO:0010721 82 0.011
response to acid chemical GO:0001101 222 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
cell cycle GO:0007049 101 0.011
cell morphogenesis GO:0000902 142 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
signal release GO:0023061 145 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
response to nutrient GO:0007584 248 0.011
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.011
calcium ion homeostasis GO:0055074 162 0.011
neuron apoptotic process GO:0051402 88 0.011
Rat
regulation of transmembrane transport GO:0034762 122 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
small molecule catabolic process GO:0044282 59 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
positive regulation of nervous system development GO:0051962 178 0.011
cell motility GO:0048870 202 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
cellular ion homeostasis GO:0006873 184 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
action potential GO:0001508 54 0.011
cellular response to external stimulus GO:0071496 118 0.011
Rat
response to other organism GO:0051707 220 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
Rat
response to cytokine GO:0034097 215 0.010
response to calcium ion GO:0051592 59 0.010
sensory organ development GO:0007423 74 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
response to purine containing compound GO:0014074 126 0.010
tube development GO:0035295 89 0.010
protein processing GO:0016485 68 0.010
endocytosis GO:0006897 84 0.010
positive regulation of signal transduction GO:0009967 175 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
chromosome segregation GO:0007059 2 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
eye morphogenesis GO:0048592 4 0.010
isoprenoid metabolic process GO:0006720 45 0.010

Hmox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
central nervous system disease DOID:331 0 0.016
musculoskeletal system disease DOID:17 0 0.016
disease of cellular proliferation DOID:14566 0 0.013
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
brain disease DOID:936 0 0.010