Rattus norvegicus

0 known processes

Pkhd1l1

polycystic kidney and hepatic disease 1-like 1

(Aliases: MGC124881)

Pkhd1l1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.091
regulation of cell proliferation GO:0042127 359 0.067
oxoacid metabolic process GO:0043436 290 0.064
programmed cell death GO:0012501 392 0.062
regulation of apoptotic process GO:0042981 335 0.061
central nervous system development GO:0007417 311 0.061
positive regulation of biosynthetic process GO:0009891 319 0.059
single organism biosynthetic process GO:0044711 342 0.058
positive regulation of programmed cell death GO:0043068 157 0.055
catabolic process GO:0009056 351 0.051
carboxylic acid metabolic process GO:0019752 289 0.049
organic acid metabolic process GO:0006082 292 0.049
organophosphate metabolic process GO:0019637 370 0.048
lipid metabolic process GO:0006629 283 0.048
retinal metabolic process GO:0042574 3 0.048
organic substance catabolic process GO:1901575 316 0.046
rna metabolic process GO:0016070 406 0.046
rna biosynthetic process GO:0032774 380 0.046
nucleobase containing small molecule metabolic process GO:0055086 316 0.045
regulation of rna biosynthetic process GO:2001141 381 0.045
positive regulation of developmental process GO:0051094 283 0.044
cellular catabolic process GO:0044248 295 0.044
regulation of multicellular organismal development GO:2000026 376 0.042
transcription dna templated GO:0006351 377 0.041
regulation of molecular function GO:0065009 398 0.040
nucleotide metabolic process GO:0009117 279 0.040
negative regulation of cell death GO:0060548 229 0.039
purine containing compound metabolic process GO:0072521 253 0.039
nucleoside phosphate metabolic process GO:0006753 283 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
response to bacterium GO:0009617 200 0.037
cellular component assembly GO:0022607 360 0.037
negative regulation of apoptotic process GO:0043066 181 0.037
positive regulation of cell death GO:0010942 184 0.036
regulation of rna metabolic process GO:0051252 391 0.036
response to oxygen levels GO:0070482 265 0.035
response to extracellular stimulus GO:0009991 380 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
nucleic acid templated transcription GO:0097659 379 0.035
single organism reproductive process GO:0044702 297 0.035
protein complex assembly GO:0006461 263 0.035
single organism catabolic process GO:0044712 283 0.034
aromatic compound catabolic process GO:0019439 168 0.033
response to decreased oxygen levels GO:0036293 237 0.033
protein phosphorylation GO:0006468 345 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
negative regulation of programmed cell death GO:0043069 183 0.032
intracellular signal transduction GO:0035556 314 0.032
macromolecule localization GO:0033036 252 0.032
amine metabolic process GO:0009308 38 0.032
response to acid chemical GO:0001101 222 0.031
response to hypoxia GO:0001666 231 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
brain development GO:0007420 247 0.031
cellular component biogenesis GO:0044085 368 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
cellular amine metabolic process GO:0044106 38 0.030
cellular nitrogen compound catabolic process GO:0044270 163 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
establishment of protein localization GO:0045184 141 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
tissue development GO:0009888 252 0.029
response to external biotic stimulus GO:0043207 221 0.029
positive regulation of apoptotic process GO:0043065 154 0.028
reproduction GO:0000003 245 0.028
cellular ketone metabolic process GO:0042180 51 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
response to molecule of bacterial origin GO:0002237 194 0.028
cellular lipid metabolic process GO:0044255 208 0.028
oxidation reduction process GO:0055114 304 0.027
multicellular organism reproduction GO:0032504 233 0.027
localization of cell GO:0051674 202 0.027
regulation of transcription dna templated GO:0006355 374 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
cell migration GO:0016477 197 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
reproductive process GO:0022414 372 0.026
apoptotic process GO:0006915 381 0.026
response to other organism GO:0051707 220 0.026
cellular chemical homeostasis GO:0055082 247 0.026
mesoderm development GO:0007498 2 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
regulation of nervous system development GO:0051960 264 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
response to cytokine GO:0034097 215 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
cation transport GO:0006812 382 0.025
nucleobase containing compound catabolic process GO:0034655 152 0.025
cell adhesion GO:0007155 110 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
response to wounding GO:0009611 254 0.024
macromolecular complex assembly GO:0065003 273 0.024
regulation of protein metabolic process GO:0051246 289 0.024
positive regulation of molecular function GO:0044093 230 0.024
regulation of membrane potential GO:0042391 110 0.024
response to carbohydrate GO:0009743 183 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
response to biotic stimulus GO:0009607 226 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
regulation of cell differentiation GO:0045595 320 0.023
metal ion transport GO:0030001 289 0.023
heterocycle catabolic process GO:0046700 167 0.023
multi organism reproductive process GO:0044703 262 0.023
purine containing compound catabolic process GO:0072523 138 0.023
positive regulation of gene expression GO:0010628 244 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
negative regulation of metabolic process GO:0009892 331 0.023
response to nutrient levels GO:0031667 370 0.022
positive regulation of cell development GO:0010720 176 0.022
purine nucleotide catabolic process GO:0006195 136 0.022
regulation of cell migration GO:0030334 128 0.022
chemical homeostasis GO:0048878 292 0.022
response to vitamin GO:0033273 131 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
regulation of cellular component organization GO:0051128 368 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
cardiovascular system development GO:0072358 134 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
homeostatic process GO:0042592 331 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
positive regulation of nervous system development GO:0051962 178 0.020
positive regulation of cellular component movement GO:0051272 102 0.020
proteolysis GO:0006508 175 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
head development GO:0060322 247 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
regulation of signal transduction GO:0009966 318 0.020
cellular ion homeostasis GO:0006873 184 0.020
protein complex biogenesis GO:0070271 263 0.020
small molecule biosynthetic process GO:0044283 124 0.020
small gtpase mediated signal transduction GO:0007264 36 0.019
regulation of cell motility GO:2000145 131 0.019
response to lipopolysaccharide GO:0032496 191 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
cellular component movement GO:0006928 248 0.019
regeneration GO:0031099 163 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
regulation of catalytic activity GO:0050790 304 0.019
regulation of neurogenesis GO:0050767 247 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
protein localization GO:0008104 191 0.018
cellular response to stress GO:0033554 269 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
response to estrogen GO:0043627 232 0.018
response to growth factor GO:0070848 189 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
regulation of protein modification process GO:0031399 194 0.018
protein oligomerization GO:0051259 191 0.018
neuron differentiation GO:0030182 368 0.018
peptidyl amino acid modification GO:0018193 126 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
purine ribonucleotide catabolic process GO:0009154 136 0.018
response to oxidative stress GO:0006979 186 0.018
regulation of cell development GO:0060284 263 0.018
cellular homeostasis GO:0019725 252 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
multi multicellular organism process GO:0044706 138 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
cell motility GO:0048870 202 0.017
gliogenesis GO:0042063 93 0.017
organophosphate catabolic process GO:0046434 148 0.017
positive regulation of cell communication GO:0010647 271 0.017
regulation of immune system process GO:0002682 123 0.017
regulation of locomotion GO:0040012 148 0.017
response to nutrient GO:0007584 248 0.017
muscle system process GO:0003012 115 0.017
ribonucleoside metabolic process GO:0009119 174 0.016
response to ketone GO:1901654 182 0.016
defense response GO:0006952 194 0.016
nucleoside catabolic process GO:0009164 126 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
circulatory system development GO:0072359 134 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
regulation of cellular localization GO:0060341 263 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
negative regulation of molecular function GO:0044092 133 0.016
response to fatty acid GO:0070542 65 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
biological adhesion GO:0022610 110 0.016
endocytosis GO:0006897 84 0.016
response to inorganic substance GO:0010035 377 0.016
negative regulation of innate immune response GO:0045824 4 0.016
response to hexose GO:0009746 144 0.015
circulatory system process GO:0003013 183 0.015
response to mechanical stimulus GO:0009612 134 0.015
vesicle mediated transport GO:0016192 181 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
positive regulation of signaling GO:0023056 270 0.015
regulation of vasculature development GO:1901342 44 0.015
regulation of system process GO:0044057 208 0.015
protein complex subunit organization GO:0071822 302 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
positive regulation of signal transduction GO:0009967 175 0.015
regulation of response to stress GO:0080134 126 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
cellular response to lipid GO:0071396 201 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
fatty acid metabolic process GO:0006631 99 0.015
purine nucleoside metabolic process GO:0042278 169 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
response to monosaccharide GO:0034284 159 0.014
ion homeostasis GO:0050801 212 0.014
heart morphogenesis GO:0003007 3 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
cytoskeleton organization GO:0007010 111 0.014
locomotion GO:0040011 237 0.014
female pregnancy GO:0007565 122 0.014
actin filament based process GO:0030029 86 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
organelle organization GO:0006996 266 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
antigen receptor mediated signaling pathway GO:0050851 1 0.014
muscle cell proliferation GO:0033002 84 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
negative regulation of gene expression GO:0010629 199 0.014
neuron development GO:0048666 286 0.014
regulation of cellular component movement GO:0051270 150 0.014
transmembrane transport GO:0055085 412 0.014
intracellular transport GO:0046907 185 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
growth GO:0040007 165 0.014
nucleotide catabolic process GO:0009166 139 0.013
cell activation GO:0001775 97 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
response to activity GO:0014823 73 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
sexual reproduction GO:0019953 148 0.013
nucleoside metabolic process GO:0009116 179 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
negative regulation of signaling GO:0023057 157 0.013
immune system process GO:0002376 204 0.013
positive regulation of endothelial cell migration GO:0010595 4 0.013
regulation of phosphorylation GO:0042325 248 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
secretion by cell GO:0032940 248 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
cellular response to external stimulus GO:0071496 118 0.013
organic hydroxy compound transport GO:0015850 77 0.013
cellular response to molecule of bacterial origin GO:0071219 56 0.013
protein transport GO:0015031 132 0.013
response to estradiol GO:0032355 164 0.013
gland development GO:0048732 155 0.013
positive regulation of transport GO:0051050 245 0.012
metal ion homeostasis GO:0055065 186 0.012
cellular cation homeostasis GO:0030003 180 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
coenzyme metabolic process GO:0006732 86 0.012
calcium ion homeostasis GO:0055074 162 0.012
regulation of organelle organization GO:0033043 80 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
carbohydrate metabolic process GO:0005975 130 0.012
gamete generation GO:0007276 124 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
organ formation GO:0048645 3 0.012
organ regeneration GO:0031100 101 0.012
regulation of response to external stimulus GO:0032101 106 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
response to alkaloid GO:0043279 132 0.012
lipid storage GO:0019915 1 0.012
regulation of catabolic process GO:0009894 113 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
neuron projection development GO:0031175 273 0.012
mapk cascade GO:0000165 140 0.012
tube development GO:0035295 89 0.012
single organism intracellular transport GO:1902582 166 0.012
cellular response to acid chemical GO:0071229 75 0.012
transmission of nerve impulse GO:0019226 42 0.012
reproductive system development GO:0061458 128 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
regulation of cell projection organization GO:0031344 175 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
gastrulation GO:0007369 2 0.012
regulation of neuron differentiation GO:0045664 208 0.012
regulation of phagocytosis engulfment GO:0060099 4 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
calcium ion transport GO:0006816 131 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
nitrogen compound transport GO:0071705 229 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
lipid biosynthetic process GO:0008610 128 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
muscle contraction GO:0006936 88 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of phagocytosis engulfment GO:0060100 4 0.011
positive regulation of cell motility GO:2000147 97 0.011
eye morphogenesis GO:0048592 4 0.011
neuronal action potential GO:0019228 35 0.011
camera type eye morphogenesis GO:0048593 2 0.011
blood circulation GO:0008015 183 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of ion transport GO:0043269 245 0.011
epithelium development GO:0060429 96 0.011
cation transmembrane transport GO:0098655 263 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
cofactor metabolic process GO:0051186 95 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cellular response to lipopolysaccharide GO:0071222 55 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
cell projection organization GO:0030030 302 0.011
urogenital system development GO:0001655 78 0.011
dna metabolic process GO:0006259 96 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
blood vessel development GO:0001568 69 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
male gamete generation GO:0048232 99 0.011
phospholipid metabolic process GO:0006644 61 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
maintenance of location GO:0051235 17 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
developmental process involved in reproduction GO:0003006 159 0.011
glial cell differentiation GO:0010001 65 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
organ morphogenesis GO:0009887 75 0.010
regulation of inflammatory response GO:0050727 48 0.010
spermatogenesis GO:0007283 99 0.010
immune response GO:0006955 104 0.010
developmental growth GO:0048589 100 0.010
single organism cellular localization GO:1902580 102 0.010
cation homeostasis GO:0055080 195 0.010
regulation of blood circulation GO:1903522 110 0.010
cytokine biosynthetic process GO:0042089 3 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
divalent inorganic cation transport GO:0072511 134 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
negative regulation of cell communication GO:0010648 158 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
response to increased oxygen levels GO:0036296 45 0.010
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.010
regulation of protein localization GO:0032880 81 0.010
regulation of mapk cascade GO:0043408 116 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010

Pkhd1l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
inherited metabolic disorder DOID:655 0 0.012