Rattus norvegicus

18 known processes

Ptpn2

protein tyrosine phosphatase, non-receptor type 2

Ptpn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal reproductive process GO:0048609 233 0.055
single organism reproductive process GO:0044702 297 0.053
rna metabolic process GO:0016070 406 0.052
transcription dna templated GO:0006351 377 0.051
rna biosynthetic process GO:0032774 380 0.051
regulation of transcription dna templated GO:0006355 374 0.051
regulation of programmed cell death GO:0043067 341 0.049
response to acid chemical GO:0001101 222 0.047
behavior GO:0007610 205 0.044
Mouse
multi organism reproductive process GO:0044703 262 0.044
Yeast
cellular response to growth factor stimulus GO:0071363 162 0.040
protein complex subunit organization GO:0071822 302 0.038
response to estrogen GO:0043627 232 0.038
reproductive process GO:0022414 372 0.037
Yeast
metal ion transport GO:0030001 289 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
Mouse
response to amino acid GO:0043200 75 0.035
reproductive structure development GO:0048608 128 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.034
response to oxygen levels GO:0070482 265 0.034
homeostatic process GO:0042592 331 0.033
Mouse
multicellular organism reproduction GO:0032504 233 0.032
regulation of rna metabolic process GO:0051252 391 0.032
response to other organism GO:0051707 220 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
macromolecular complex subunit organization GO:0043933 339 0.031
positive regulation of cell differentiation GO:0045597 217 0.031
nucleic acid templated transcription GO:0097659 379 0.030
metal ion homeostasis GO:0055065 186 0.029
protein oligomerization GO:0051259 191 0.029
negative regulation of rna biosynthetic process GO:1902679 118 0.028
regulation of necroptotic process GO:0060544 2 0.028
response to extracellular stimulus GO:0009991 380 0.028
response to peptide GO:1901652 292 0.028
Mouse Rat
cellular response to organic cyclic compound GO:0071407 202 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
response to hydrogen peroxide GO:0042542 89 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
Human Yeast Mouse
response to radiation GO:0009314 137 0.027
cellular response to oxygen containing compound GO:1901701 386 0.026
Mouse Rat
immune response GO:0006955 104 0.026
Human Mouse
carboxylic acid metabolic process GO:0019752 289 0.026
aging GO:0007568 241 0.026
central nervous system development GO:0007417 311 0.026
positive regulation of signaling GO:0023056 270 0.026
response to estradiol GO:0032355 164 0.026
intracellular signal transduction GO:0035556 314 0.026
Human Yeast Mouse
regulation of cell development GO:0060284 263 0.025
cation transmembrane transport GO:0098655 263 0.025
cation homeostasis GO:0055080 195 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
regulation of dna metabolic process GO:0051052 60 0.024
response to corticosteroid GO:0031960 235 0.024
response to ketone GO:1901654 182 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
Mouse
negative regulation of programmed cell death GO:0043069 183 0.024
regulation of nervous system development GO:0051960 264 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
reproduction GO:0000003 245 0.023
Yeast
secretion by cell GO:0032940 248 0.023
response to nutrient GO:0007584 248 0.023
positive regulation of cell development GO:0010720 176 0.023
response to growth factor GO:0070848 189 0.023
response to bacterium GO:0009617 200 0.023
regulation of secretion GO:0051046 224 0.023
cellular response to endogenous stimulus GO:0071495 377 0.022
Mouse Rat
cellular amino acid metabolic process GO:0006520 107 0.022
regulation of neuron death GO:1901214 115 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
cellular ion homeostasis GO:0006873 184 0.022
neuron development GO:0048666 286 0.021
protein complex assembly GO:0006461 263 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
response to mechanical stimulus GO:0009612 134 0.021
response to glucocorticoid GO:0051384 223 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
sex differentiation GO:0007548 113 0.021
response to nutrient levels GO:0031667 370 0.021
transmembrane transport GO:0055085 412 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
Mouse Rat
ion homeostasis GO:0050801 212 0.021
regulation of secretion by cell GO:1903530 208 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
head development GO:0060322 247 0.020
protein complex biogenesis GO:0070271 263 0.020
protein heterooligomerization GO:0051291 89 0.020
dna metabolic process GO:0006259 96 0.020
cell cell signaling GO:0007267 335 0.020
reproductive system development GO:0061458 128 0.020
response to biotic stimulus GO:0009607 226 0.019
cellular response to stress GO:0033554 269 0.019
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
cellular amine metabolic process GO:0044106 38 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
immune system process GO:0002376 204 0.019
Human Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.019
positive regulation of gene expression GO:0010628 244 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
response to inorganic substance GO:0010035 377 0.019
cellular cation homeostasis GO:0030003 180 0.019
developmental process involved in reproduction GO:0003006 159 0.019
intracellular transport GO:0046907 185 0.019
gamete generation GO:0007276 124 0.019
cation transport GO:0006812 382 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
Mouse
regulation of cellular component organization GO:0051128 368 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
neuron projection development GO:0031175 273 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
Mouse Rat
cellular component assembly GO:0022607 360 0.018
regulation of neurogenesis GO:0050767 247 0.018
response to alkaloid GO:0043279 132 0.018
cellular chemical homeostasis GO:0055082 247 0.018
response to toxic substance GO:0009636 133 0.017
macromolecular complex assembly GO:0065003 273 0.017
nuclear transport GO:0051169 49 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
response to external biotic stimulus GO:0043207 221 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
response to lipopolysaccharide GO:0032496 191 0.017
development of primary sexual characteristics GO:0045137 107 0.017
response to carbohydrate GO:0009743 183 0.017
regulation of catalytic activity GO:0050790 304 0.017
Yeast
inorganic ion transmembrane transport GO:0098660 229 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
regulation of cell projection organization GO:0031344 175 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
multi multicellular organism process GO:0044706 138 0.016
regulation of cellular localization GO:0060341 263 0.016
protein phosphorylation GO:0006468 345 0.016
Human Yeast Mouse
positive regulation of developmental process GO:0051094 283 0.016
regulation of signal transduction GO:0009966 318 0.016
Human Yeast Mouse Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
protein transport GO:0015031 132 0.016
cytoplasmic transport GO:0016482 115 0.016
cellular ketone metabolic process GO:0042180 51 0.016
Mouse
negative regulation of cell communication GO:0010648 158 0.016
Human Yeast Mouse
divalent inorganic cation transport GO:0072511 134 0.016
programmed cell death GO:0012501 392 0.016
regulation of immune system process GO:0002682 123 0.016
Human Mouse
regulation of apoptotic process GO:0042981 335 0.016
amine metabolic process GO:0009308 38 0.016
cellular response to cytokine stimulus GO:0071345 127 0.015
Human Mouse
negative regulation of metabolic process GO:0009892 331 0.015
Human Yeast Mouse
cellular component biogenesis GO:0044085 368 0.015
Yeast
response to oxidative stress GO:0006979 186 0.015
regulation of hormone levels GO:0010817 187 0.015
positive regulation of molecular function GO:0044093 230 0.015
nitrogen compound transport GO:0071705 229 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of cell communication GO:0010647 271 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
apoptotic process GO:0006915 381 0.014
calcium ion homeostasis GO:0055074 162 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
Yeast
nucleotide metabolic process GO:0009117 279 0.014
regulation of cell differentiation GO:0045595 320 0.014
Mouse
negative regulation of gene expression GO:0010629 199 0.014
eye morphogenesis GO:0048592 4 0.014
positive regulation of signal transduction GO:0009967 175 0.014
gliogenesis GO:0042063 93 0.014
ion transmembrane transport GO:0034220 365 0.014
regulation of synaptic transmission GO:0050804 141 0.014
cellular homeostasis GO:0019725 252 0.014
cellular response to acid chemical GO:0071229 75 0.014
chemical homeostasis GO:0048878 292 0.014
Mouse
response to monosaccharide GO:0034284 159 0.014
catabolic process GO:0009056 351 0.013
circadian rhythm GO:0007623 88 0.013
response to vitamin GO:0033273 131 0.013
cellular component morphogenesis GO:0032989 155 0.013
hormone transport GO:0009914 121 0.013
regulation of protein metabolic process GO:0051246 289 0.013
Human Yeast Mouse
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
organic acid transport GO:0015849 116 0.013
oxidation reduction process GO:0055114 304 0.013
cellular response to alcohol GO:0097306 87 0.013
neuron differentiation GO:0030182 368 0.013
positive regulation of cytokine production GO:0001819 42 0.013
response to cytokine GO:0034097 215 0.013
Human Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
regulation of cell proliferation GO:0042127 359 0.012
Human
response to metal ion GO:0010038 253 0.012
anion transport GO:0006820 178 0.012
rna localization GO:0006403 4 0.012
positive regulation of transport GO:0051050 245 0.012
positive regulation of nervous system development GO:0051962 178 0.012
lipid metabolic process GO:0006629 283 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
Mouse Rat
locomotion GO:0040011 237 0.012
Mouse
regeneration GO:0031099 163 0.012
cell growth GO:0016049 104 0.012
Yeast
muscle contraction GO:0006936 88 0.012
multicellular organism growth GO:0035264 1 0.012
response to electrical stimulus GO:0051602 56 0.012
regulation of molecular function GO:0065009 398 0.012
Yeast
cytokine production GO:0001816 61 0.012
organic acid metabolic process GO:0006082 292 0.012
carboxylic acid transport GO:0046942 115 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
negative regulation of signaling GO:0023057 157 0.012
Human Yeast Mouse
regulation of phosphate metabolic process GO:0019220 349 0.012
Human Yeast Mouse
response to hypoxia GO:0001666 231 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
secretion GO:0046903 307 0.012
defense response GO:0006952 194 0.011
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.011
Human Yeast Mouse
anatomical structure morphogenesis GO:0009653 298 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.011
sexual reproduction GO:0019953 148 0.011
Yeast
negative regulation of cell death GO:0060548 229 0.011
response to decreased oxygen levels GO:0036293 237 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
cell cycle GO:0007049 101 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.011
muscle system process GO:0003012 115 0.011
rhythmic process GO:0048511 156 0.011
cellular response to lipid GO:0071396 201 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
sensory organ development GO:0007423 74 0.011
protein import GO:0017038 37 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
Yeast Mouse
response to peptide hormone GO:0043434 278 0.011
Mouse Rat
fatty acid metabolic process GO:0006631 99 0.011
ras protein signal transduction GO:0007265 29 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
regulation of neuron differentiation GO:0045664 208 0.011
negative regulation of apoptotic process GO:0043066 181 0.010
purine containing compound metabolic process GO:0072521 253 0.010
oxoacid metabolic process GO:0043436 290 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
Human Mouse Rat
response to dexamethasone GO:0071548 49 0.010
positive regulation of multicellular organismal process GO:0051240 387 0.010
single organism biosynthetic process GO:0044711 342 0.010
Mouse
positive regulation of apoptotic process GO:0043065 154 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
brain development GO:0007420 247 0.010
response to light stimulus GO:0009416 52 0.010
negative regulation of neuron death GO:1901215 69 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
Human Yeast Mouse
response to cadmium ion GO:0046686 35 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
male sex differentiation GO:0046661 64 0.010

Ptpn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.010