Rattus norvegicus

106 known processes

Kidins220

kinase D-interacting substrate 220

(Aliases: ARMS)

Kidins220 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal development GO:2000026 376 0.167
regulation of cell differentiation GO:0045595 320 0.132
regulation of neurogenesis GO:0050767 247 0.127
single organism intracellular transport GO:1902582 166 0.107
positive regulation of transcription dna templated GO:0045893 197 0.100
brain development GO:0007420 247 0.100
central nervous system development GO:0007417 311 0.084
single organism catabolic process GO:0044712 283 0.077
positive regulation of cellular component organization GO:0051130 200 0.071
macromolecular complex subunit organization GO:0043933 339 0.066
organelle organization GO:0006996 266 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.064
regulation of cell development GO:0060284 263 0.064
cellular response to stress GO:0033554 269 0.062
positive regulation of cell differentiation GO:0045597 217 0.060
regulation of neuron projection development GO:0010975 161 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
organophosphate catabolic process GO:0046434 148 0.056
neuron projection development GO:0031175 273 0.055
regulation of nervous system development GO:0051960 264 0.055
regulation of cellular amino acid metabolic process GO:0006521 2 0.054
positive regulation of phosphorus metabolic process GO:0010562 262 0.051
regulation of cellular amine metabolic process GO:0033238 8 0.049
response to extracellular stimulus GO:0009991 380 0.049
regulation of cellular ketone metabolic process GO:0010565 27 0.049
catabolic process GO:0009056 351 0.048
positive regulation of catalytic activity GO:0043085 184 0.046
neuron differentiation GO:0030182 368 0.046
head development GO:0060322 247 0.045
amine metabolic process GO:0009308 38 0.044
regulation of cellular component organization GO:0051128 368 0.044
cellular ketone metabolic process GO:0042180 51 0.043
regulation of phosphorylation GO:0042325 248 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
positive regulation of cell development GO:0010720 176 0.042
cellular component biogenesis GO:0044085 368 0.042
negative regulation of metabolic process GO:0009892 331 0.042
regulation of glycoprotein biosynthetic process GO:0010559 6 0.041
positive regulation of neuron projection development GO:0010976 99 0.040
positive regulation of phosphate metabolic process GO:0045937 262 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.039
divalent inorganic cation homeostasis GO:0072507 165 0.038
organic acid metabolic process GO:0006082 292 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
response to acid chemical GO:0001101 222 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
response to peptide GO:1901652 292 0.037
regulation of protein phosphorylation GO:0001932 183 0.037
axonogenesis GO:0007409 71 0.037
cellular metal ion homeostasis GO:0006875 172 0.036
response to oxygen levels GO:0070482 265 0.036
regulation of phosphate metabolic process GO:0019220 349 0.035
positive regulation of nucleotide metabolic process GO:0045981 91 0.034
positive regulation of hydrolase activity GO:0051345 86 0.034
purine ribonucleotide metabolic process GO:0009150 227 0.034
monovalent inorganic cation transport GO:0015672 172 0.033
cellular amine metabolic process GO:0044106 38 0.032
protein complex biogenesis GO:0070271 263 0.032
response to oxidative stress GO:0006979 186 0.032
glycosyl compound metabolic process GO:1901657 182 0.032
regulation of signal transduction GO:0009966 318 0.032
nucleotide metabolic process GO:0009117 279 0.031
chemical homeostasis GO:0048878 292 0.030
cellular calcium ion homeostasis GO:0006874 160 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
protein complex assembly GO:0006461 263 0.029
cellular component morphogenesis GO:0032989 155 0.029
Mouse
positive regulation of molecular function GO:0044093 230 0.029
regulation of cell projection organization GO:0031344 175 0.028
response to radiation GO:0009314 137 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
intracellular transport GO:0046907 185 0.028
macromolecular complex assembly GO:0065003 273 0.027
positive regulation of nucleoside metabolic process GO:0045979 55 0.027
cell projection organization GO:0030030 302 0.027
regulation of neuron differentiation GO:0045664 208 0.027
regulation of rna biosynthetic process GO:2001141 381 0.026
oxoacid metabolic process GO:0043436 290 0.026
secretion by cell GO:0032940 248 0.026
cation homeostasis GO:0055080 195 0.026
regulation of programmed cell death GO:0043067 341 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
response to growth factor GO:0070848 189 0.025
purine containing compound metabolic process GO:0072521 253 0.024
regulation of protein metabolic process GO:0051246 289 0.024
nucleic acid templated transcription GO:0097659 379 0.024
neurological system process GO:0050877 219 0.024
calcium ion homeostasis GO:0055074 162 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
positive regulation of signaling GO:0023056 270 0.023
cellular homeostasis GO:0019725 252 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
ion homeostasis GO:0050801 212 0.023
regulation of hydrolase activity GO:0051336 143 0.023
response to peptide hormone GO:0043434 278 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
regulation of apoptotic process GO:0042981 335 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
ribonucleotide metabolic process GO:0009259 231 0.022
protein complex subunit organization GO:0071822 302 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
positive regulation of gene expression GO:0010628 244 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
positive regulation of nervous system development GO:0051962 178 0.022
cellular ion homeostasis GO:0006873 184 0.022
purine nucleotide metabolic process GO:0006163 229 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
cellular cation homeostasis GO:0030003 180 0.021
regulation of transcription dna templated GO:0006355 374 0.021
positive regulation of gtp catabolic process GO:0033126 48 0.021
cellular catabolic process GO:0044248 295 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
stress activated mapk cascade GO:0051403 35 0.019
response to carbohydrate GO:0009743 183 0.019
neuron apoptotic process GO:0051402 88 0.019
regulation of molecular function GO:0065009 398 0.019
adult locomotory behavior GO:0008344 4 0.019
cell projection morphogenesis GO:0048858 123 0.019
Mouse
negative regulation of cell differentiation GO:0045596 99 0.019
regulation of cellular localization GO:0060341 263 0.019
protein phosphorylation GO:0006468 345 0.019
cellular component movement GO:0006928 248 0.019
intracellular signal transduction GO:0035556 314 0.018
organic substance catabolic process GO:1901575 316 0.018
programmed cell death GO:0012501 392 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
response to inorganic substance GO:0010035 377 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
purine containing compound catabolic process GO:0072523 138 0.018
negative regulation of gene expression GO:0010629 199 0.018
multi organism reproductive process GO:0044703 262 0.017
cell motility GO:0048870 202 0.017
regulation of response to external stimulus GO:0032101 106 0.017
calcium ion transport GO:0006816 131 0.017
positive regulation of nucleotide catabolic process GO:0030813 53 0.017
homeostatic process GO:0042592 331 0.017
metal ion homeostasis GO:0055065 186 0.017
regulation of catalytic activity GO:0050790 304 0.017
regulation of catabolic process GO:0009894 113 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
learning or memory GO:0007611 90 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
cellular chemical homeostasis GO:0055082 247 0.017
positive regulation of ion transport GO:0043270 94 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
forebrain development GO:0030900 98 0.016
regulation of nucleoside metabolic process GO:0009118 66 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
Mouse
positive regulation of cell projection organization GO:0031346 111 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
regulation of rna metabolic process GO:0051252 391 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
carbohydrate metabolic process GO:0005975 130 0.015
response to aluminum ion GO:0010044 10 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
cgmp biosynthetic process GO:0006182 15 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
axon development GO:0061564 96 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
response to hypoxia GO:0001666 231 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.015
cell migration GO:0016477 197 0.015
positive regulation of transport GO:0051050 245 0.015
neuron projection morphogenesis GO:0048812 122 0.015
Mouse
memory GO:0007613 54 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
nucleotide catabolic process GO:0009166 139 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
transmission of nerve impulse GO:0019226 42 0.015
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.014
regulation of secretion GO:0051046 224 0.014
positive regulation of developmental process GO:0051094 283 0.014
response to light stimulus GO:0009416 52 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
regulation of transferase activity GO:0051338 123 0.014
single organism organelle organization GO:1902589 180 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
regulation of secretion by cell GO:1903530 208 0.014
response to organophosphorus GO:0046683 102 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
sexual reproduction GO:0019953 148 0.014
regulation of anatomical structure size GO:0090066 135 0.014
response to nutrient levels GO:0031667 370 0.014
axon choice point recognition GO:0016198 2 0.014
cellular component assembly GO:0022607 360 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
organophosphate metabolic process GO:0019637 370 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
secretion GO:0046903 307 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
cell part morphogenesis GO:0032990 123 0.013
Mouse
regulation of axonogenesis GO:0050770 37 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
Mouse
regulation of cell proliferation GO:0042127 359 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
potassium ion transport GO:0006813 97 0.013
negative regulation of cell communication GO:0010648 158 0.013
alcohol metabolic process GO:0006066 77 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
cation transmembrane transport GO:0098655 263 0.013
response to reactive oxygen species GO:0000302 120 0.013
protein transport GO:0015031 132 0.013
nucleoside metabolic process GO:0009116 179 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of calcium ion transport GO:0051924 77 0.013
organic hydroxy compound transport GO:0015850 77 0.013
protein localization GO:0008104 191 0.013
regulation of locomotion GO:0040012 148 0.013
nucleoside catabolic process GO:0009164 126 0.013
multicellular organismal signaling GO:0035637 44 0.012
neuron development GO:0048666 286 0.012
growth GO:0040007 165 0.012
synaptic transmission GO:0007268 235 0.012
response to decreased oxygen levels GO:0036293 237 0.012
regulation of axon extension GO:0030516 24 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
cell growth GO:0016049 104 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
regulation of jnk cascade GO:0046328 19 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
protein oligomerization GO:0051259 191 0.012
single organism biosynthetic process GO:0044711 342 0.012
response to metal ion GO:0010038 253 0.012
rna metabolic process GO:0016070 406 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
divalent metal ion transport GO:0070838 132 0.012
positive regulation of tor signaling GO:0032008 2 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
negative regulation of developmental process GO:0051093 125 0.012
vesicle mediated transport GO:0016192 181 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
sequestering of calcium ion GO:0051208 8 0.012
immune system process GO:0002376 204 0.012
regulation of cellular response to stress GO:0080135 49 0.012
aromatic compound catabolic process GO:0019439 168 0.012
positive regulation of catabolic process GO:0009896 78 0.012
heterocycle catabolic process GO:0046700 167 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
positive regulation of norepinephrine secretion GO:0010701 4 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
anion transport GO:0006820 178 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
response to wounding GO:0009611 254 0.011
ras protein signal transduction GO:0007265 29 0.011
synapse organization GO:0050808 46 0.011
regulation of glycoprotein metabolic process GO:1903018 6 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of immune system process GO:0002682 123 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
axon cargo transport GO:0008088 1 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
macromolecule localization GO:0033036 252 0.011
regulation of ion transport GO:0043269 245 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
apoptotic process GO:0006915 381 0.011
gtp metabolic process GO:0046039 72 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
transcription dna templated GO:0006351 377 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
sensory perception GO:0007600 101 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
regulation of developmental growth GO:0048638 45 0.011
cell morphogenesis GO:0000902 142 0.011
Mouse
regulation of body fluid levels GO:0050878 90 0.010
motor neuron axon guidance GO:0008045 1 0.010
cell cell signaling GO:0007267 335 0.010
gtp catabolic process GO:0006184 71 0.010
positive regulation of gtpase activity GO:0043547 47 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
developmental growth GO:0048589 100 0.010
rna localization GO:0006403 4 0.010
cyclic purine nucleotide metabolic process GO:0052652 62 0.010
response to monosaccharide GO:0034284 159 0.010
transmembrane transport GO:0055085 412 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
dna integrity checkpoint GO:0031570 2 0.010
sensory perception of bitter taste GO:0050913 4 0.010

Kidins220 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.048
central nervous system disease DOID:331 0 0.037
brain disease DOID:936 0 0.019
epilepsy syndrome DOID:1826 0 0.017
electroclinical syndrome DOID:0050701 0 0.017
neonatal period electroclinical syndrome DOID:0050702 0 0.017
ohtahara syndrome DOID:0050709 0 0.017
disease of metabolism DOID:0014667 0 0.010