|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.870
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.790
|
Worm |
|
|
cellular component movement
|
GO:0006928 |
248 |
0.739
|
Rat |
|
|
apoptotic process
|
GO:0006915 |
381 |
0.681
|
Worm |
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.616
|
Yeast Mouse |
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.597
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.578
|
Human Fly |
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.545
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.525
|
Rat |
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.513
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.482
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.461
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.453
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.446
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.423
|
Rat |
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.414
|
Yeast Fly |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
152 |
0.409
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.404
|
Human Yeast Fly |
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.402
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.401
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.399
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.394
|
Human Fly |
|
|
metal ion transport
|
GO:0030001 |
289 |
0.392
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.383
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.381
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.371
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.361
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.352
|
Rat |
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.332
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
49 |
0.326
|
Worm Fly |
|
|
immune system process
|
GO:0002376 |
204 |
0.324
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.317
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.307
|
Yeast Worm |
|
|
cation transport
|
GO:0006812 |
382 |
0.303
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.293
|
Yeast Worm |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.290
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.289
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.276
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.274
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.273
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.269
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.260
|
Yeast Worm |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.256
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.256
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.254
|
Yeast Worm Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.249
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
35 |
0.249
|
Fly |
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.246
|
Worm |
|
|
positive regulation of monooxygenase activity
|
GO:0032770 |
5 |
0.246
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.245
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.243
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.238
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.237
|
Worm |
|
|
immune effector process
|
GO:0002252 |
53 |
0.236
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.226
|
Rat |
|
|
behavior
|
GO:0007610 |
205 |
0.226
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.224
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.223
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
68 |
0.220
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.219
|
|
|
|
aging
|
GO:0007568 |
241 |
0.212
|
Worm |
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.211
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.204
|
Human Yeast |
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.201
|
Human Yeast Fly |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.200
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.199
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.199
|
|
|
|
positive regulation of oxidoreductase activity
|
GO:0051353 |
7 |
0.198
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.196
|
Worm |
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.195
|
Zebrafish Mouse Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
48 |
0.195
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.187
|
Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.187
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.186
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.185
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.184
|
Human |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.183
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.182
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.181
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.181
|
Worm |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.177
|
|
|
|
response to light stimulus
|
GO:0009416 |
52 |
0.175
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.173
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.171
|
Rat |
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.167
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.166
|
Human Fly |
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.165
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.164
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.164
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.163
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.162
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.159
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.157
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.157
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.156
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
86 |
0.154
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.153
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.150
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.150
|
Human Yeast Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.149
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.149
|
Human Yeast Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.149
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.147
|
Yeast Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.147
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.144
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.143
|
Rat |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
43 |
0.143
|
Human |
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.142
|
Human |
|
|
response to wounding
|
GO:0009611 |
254 |
0.140
|
Fly |
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.137
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
4 |
0.136
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.136
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.133
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.132
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.131
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.128
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.128
|
Worm Fly |
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.128
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.127
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.127
|
|
|
|
glucocorticoid biosynthetic process
|
GO:0006704 |
5 |
0.126
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.126
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.126
|
Fly |
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.125
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.125
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.125
|
Human Fly |
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.125
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.124
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.123
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.122
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.120
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.120
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.120
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.119
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.118
|
Worm Fly |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.116
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.115
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.115
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.115
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.114
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.114
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.113
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.112
|
|
|
|
protein targeting
|
GO:0006605 |
61 |
0.112
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.112
|
|
|
|
gtp catabolic process
|
GO:0006184 |
71 |
0.111
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.111
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.110
|
Yeast Fly |
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
4 |
0.110
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.109
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
61 |
0.108
|
|
|
|
protein import into nucleus
|
GO:0006606 |
35 |
0.107
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.107
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.106
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.106
|
|
|
|
cellular potassium ion homeostasis
|
GO:0030007 |
1 |
0.106
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.105
|
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.105
|
Zebrafish |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.104
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.102
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.101
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.100
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.099
|
Mouse |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.099
|
|
|
|
nuclear transport
|
GO:0051169 |
49 |
0.099
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.099
|
Fly |
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.097
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.096
|
Fly |
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.095
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.094
|
|
|
|
protein localization to organelle
|
GO:0033365 |
57 |
0.094
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.094
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.094
|
Fly |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.093
|
Worm Fly |
|
|
response to cytokine
|
GO:0034097 |
215 |
0.093
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.092
|
Worm |
|
|
regulation of system process
|
GO:0044057 |
208 |
0.092
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.091
|
Yeast |
|
|
sensory perception
|
GO:0007600 |
101 |
0.090
|
Mouse Rat |
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.089
|
Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.089
|
Zebrafish |
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.088
|
Yeast Worm |
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.085
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.084
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.084
|
Rat |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.083
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.083
|
|
|
|
potassium ion homeostasis
|
GO:0055075 |
2 |
0.081
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.081
|
Human |
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.080
|
|
|
|
sodium ion transport
|
GO:0006814 |
82 |
0.080
|
|
|
|
single organism nuclear import
|
GO:1902593 |
35 |
0.079
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.079
|
Yeast |
|
|
secretion by cell
|
GO:0032940 |
248 |
0.077
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.077
|
Human |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.077
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.077
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.076
|
Human Fly |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.076
|
|
|
|
oxidation reduction process
|
GO:0055114 |
304 |
0.075
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.075
|
|
|
|
cellular sodium ion homeostasis
|
GO:0006883 |
4 |
0.073
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.073
|
Fly |
|
|
protein transport
|
GO:0015031 |
132 |
0.073
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.073
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.073
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.072
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.072
|
Zebrafish |
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.071
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
52 |
0.071
|
|
|
|
cell cycle process
|
GO:0022402 |
57 |
0.071
|
Yeast Worm Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.071
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
77 |
0.071
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
83 |
0.070
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.070
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.069
|
Fly |
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.069
|
Human Yeast Fly |
|
|
response to temperature stimulus
|
GO:0009266 |
94 |
0.069
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.069
|
Worm |
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.068
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
37 |
0.068
|
Fly |
|
|
mitotic spindle organization
|
GO:0007052 |
2 |
0.067
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.067
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.067
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.066
|
Fly |
|
|
response to radiation
|
GO:0009314 |
137 |
0.066
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.065
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.065
|
Human Fly |
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.064
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.064
|
Human Yeast Fly |
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.064
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.064
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.063
|
|
|
|
locomotory behavior
|
GO:0007626 |
15 |
0.063
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.063
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.062
|
Yeast Fly |
|
|
lipid localization
|
GO:0010876 |
62 |
0.062
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
11 |
0.061
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.061
|
Worm |
|
|
intracellular transport
|
GO:0046907 |
185 |
0.061
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.061
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.061
|
Yeast Worm |
|
|
blood circulation
|
GO:0008015 |
183 |
0.060
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.060
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.060
|
Human Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.060
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.060
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.058
|
Rat Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
20 |
0.058
|
Yeast |
|
|
mitochondrial transport
|
GO:0006839 |
19 |
0.057
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.057
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.056
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.056
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.056
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.056
|
Yeast |
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.056
|
Yeast |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.056
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
81 |
0.055
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.055
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.055
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.055
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.055
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.054
|
Mouse Fly |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
49 |
0.054
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.054
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.054
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
78 |
0.053
|
|
|
|
mitochondrion organization
|
GO:0007005 |
35 |
0.053
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.053
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.053
|
Fly |
|
|
protein localization
|
GO:0008104 |
191 |
0.052
|
|
|
|
lymphoid progenitor cell differentiation
|
GO:0002320 |
2 |
0.052
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.051
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.051
|
Human Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
27 |
0.051
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
17 |
0.051
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.050
|
|
|
|
detection of visible light
|
GO:0009584 |
3 |
0.050
|
|
|
|
angiogenesis
|
GO:0001525 |
53 |
0.050
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.050
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.050
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.049
|
Human Fly |
|
|
heart process
|
GO:0003015 |
57 |
0.049
|
|
|
|
translation
|
GO:0006412 |
35 |
0.049
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.049
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.049
|
Mouse Fly |
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.049
|
|
|
|
phototransduction visible light
|
GO:0007603 |
2 |
0.048
|
|
|
|
respiratory system development
|
GO:0060541 |
45 |
0.048
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.048
|
Fly |
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.048
|
Human Fly |
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.048
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
84 |
0.047
|
|
|
|
protein import
|
GO:0017038 |
37 |
0.047
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.047
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.047
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
44 |
0.046
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.046
|
|
|
|
regulation of nitric oxide synthase activity
|
GO:0050999 |
8 |
0.046
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.046
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.046
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.046
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
28 |
0.046
|
Yeast |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.045
|
|
|
|
microtubule based process
|
GO:0007017 |
36 |
0.045
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.045
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
50 |
0.045
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
1 |
0.045
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.045
|
Zebrafish |
|
|
lipid modification
|
GO:0030258 |
52 |
0.045
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.044
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.044
|
Human Mouse Fly |
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.043
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.043
|
Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.043
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.043
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.043
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.043
|
|
|
|
organelle localization
|
GO:0051640 |
55 |
0.043
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.043
|
Zebrafish Fly |
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.042
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
67 |
0.042
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.042
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.041
|
|
|
|
organelle fission
|
GO:0048285 |
25 |
0.041
|
Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
37 |
0.041
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.041
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
4 |
0.041
|
|
|
|
atp catabolic process
|
GO:0006200 |
54 |
0.041
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.040
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.040
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.040
|
|
|
|
growth
|
GO:0040007 |
165 |
0.040
|
Yeast |
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.040
|
Zebrafish |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.040
|
Yeast |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
77 |
0.039
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.039
|
Yeast |
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.039
|
Fly |
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.039
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
120 |
0.039
|
Fly |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.039
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
27 |
0.039
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.038
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.038
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.038
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.038
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
28 |
0.038
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.037
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
89 |
0.037
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.037
|
|
|
|
regulation of cell growth
|
GO:0001558 |
85 |
0.037
|
|
|
|
regulation of glucocorticoid metabolic process
|
GO:0031943 |
2 |
0.037
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.037
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.037
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.037
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.036
|
|
|
|
response to insulin
|
GO:0032868 |
133 |
0.036
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
17 |
0.036
|
|
|
|
spermatogenesis
|
GO:0007283 |
99 |
0.035
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
51 |
0.035
|
|
|
|
head development
|
GO:0060322 |
247 |
0.035
|
Zebrafish |
|
|
response to metal ion
|
GO:0010038 |
253 |
0.035
|
Fly |
|
|
male gamete generation
|
GO:0048232 |
99 |
0.035
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.035
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.034
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.034
|
|
|
|
regeneration
|
GO:0031099 |
163 |
0.034
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.034
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
16 |
0.034
|
|
|
|
response to retinoic acid
|
GO:0032526 |
63 |
0.034
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.034
|
|
|
|
actin filament organization
|
GO:0007015 |
42 |
0.034
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.034
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.034
|
Zebrafish |
|
|
mechanoreceptor differentiation
|
GO:0042490 |
2 |
0.033
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
67 |
0.033
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.033
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
29 |
0.033
|
|
|
|
sodium ion export
|
GO:0071436 |
1 |
0.033
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.033
|
Fly |
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
2 |
0.033
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
53 |
0.032
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.032
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
2 |
0.032
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.032
|
Rat Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
20 |
0.032
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.032
|
Zebrafish |
|
|
cellular component maintenance
|
GO:0043954 |
4 |
0.032
|
Fly |
|
|
regulation of phosphatidylinositol dephosphorylation
|
GO:0060304 |
1 |
0.032
|
|
|
|
salivary gland development
|
GO:0007431 |
3 |
0.032
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.031
|
Zebrafish |
|
|
skeletal muscle tissue development
|
GO:0007519 |
31 |
0.031
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.031
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.031
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
71 |
0.031
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.030
|
Rat |
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
11 |
0.030
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.030
|
Human Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.030
|
Human Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.030
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
1 |
0.030
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.030
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
50 |
0.030
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
49 |
0.030
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.029
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.029
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.029
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.029
|
|
|
|
reproductive system development
|
GO:0061458 |
128 |
0.029
|
Worm |
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.029
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.028
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
1 |
0.028
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
49 |
0.028
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.028
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.028
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
4 |
0.028
|
|
|
|
cytokinetic process
|
GO:0032506 |
1 |
0.028
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
71 |
0.028
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
41 |
0.027
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.027
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
71 |
0.027
|
|
|
|
regulation of protein processing
|
GO:0070613 |
50 |
0.027
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
33 |
0.027
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
10 |
0.027
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
34 |
0.027
|
Yeast |
|
|
response to estradiol
|
GO:0032355 |
164 |
0.027
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.027
|
Human |
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.026
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.026
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
38 |
0.026
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.026
|
|
|
|
cell projection assembly
|
GO:0030031 |
21 |
0.026
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.026
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.026
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.026
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.026
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.025
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.025
|
Human |
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
2 |
0.025
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.025
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
58 |
0.025
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.025
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.025
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
8 |
0.025
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.025
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
8 |
0.025
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.025
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
66 |
0.025
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
88 |
0.025
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.025
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
25 |
0.024
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.024
|
|
|
|
protein homooligomerization
|
GO:0051260 |
91 |
0.024
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
29 |
0.024
|
Human Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.024
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.024
|
|
|
|
axon guidance
|
GO:0007411 |
24 |
0.024
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.024
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
38 |
0.024
|
Yeast |
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
2 |
0.024
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
65 |
0.024
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.024
|
Mouse |
|
|
neuromuscular process
|
GO:0050905 |
2 |
0.024
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.023
|
|
|
|
steroid metabolic process
|
GO:0008202 |
73 |
0.023
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
6 |
0.023
|
|
|
|
b cell differentiation
|
GO:0030183 |
2 |
0.023
|
|
|
|
organelle assembly
|
GO:0070925 |
22 |
0.023
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
23 |
0.023
|
|
|
|
gtp metabolic process
|
GO:0046039 |
72 |
0.023
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
65 |
0.023
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.023
|
Fly |
|
|
phospholipid metabolic process
|
GO:0006644 |
61 |
0.023
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.023
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.023
|
Fly |
|
|
amide transport
|
GO:0042886 |
105 |
0.022
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
41 |
0.022
|
Human Fly |
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.022
|
Fly |
|
|
wound healing
|
GO:0042060 |
122 |
0.022
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.022
|
|
|
|
heart development
|
GO:0007507 |
72 |
0.022
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.022
|
Mouse |
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.021
|
|
|
|
atp metabolic process
|
GO:0046034 |
72 |
0.021
|
|
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
4 |
0.021
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
3 |
0.021
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.021
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
17 |
0.021
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
29 |
0.021
|
|
|
|
olfactory bulb interneuron differentiation
|
GO:0021889 |
1 |
0.021
|
|
|
|
ear development
|
GO:0043583 |
21 |
0.021
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
52 |
0.021
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.021
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.021
|
|
