Rattus norvegicus

0 known processes

Dner

delta/notch-like EGF repeat containing

Dner biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.060
organic acid metabolic process GO:0006082 292 0.054
carboxylic acid metabolic process GO:0019752 289 0.046
cellular response to oxygen containing compound GO:1901701 386 0.036
central nervous system development GO:0007417 311 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
neuron differentiation GO:0030182 368 0.035
response to nutrient levels GO:0031667 370 0.035
neuron projection development GO:0031175 273 0.035
regulation of multicellular organismal development GO:2000026 376 0.034
regulation of transcription dna templated GO:0006355 374 0.034
reproductive process GO:0022414 372 0.033
anatomical structure morphogenesis GO:0009653 298 0.032
regulation of nervous system development GO:0051960 264 0.032
cell projection organization GO:0030030 302 0.031
response to estrogen GO:0043627 232 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
rna metabolic process GO:0016070 406 0.030
nucleic acid templated transcription GO:0097659 379 0.030
reproduction GO:0000003 245 0.030
cellular component biogenesis GO:0044085 368 0.029
response to extracellular stimulus GO:0009991 380 0.029
transcription dna templated GO:0006351 377 0.029
head development GO:0060322 247 0.029
response to metal ion GO:0010038 253 0.029
regulation of cell differentiation GO:0045595 320 0.029
negative regulation of metabolic process GO:0009892 331 0.028
cellular ketone metabolic process GO:0042180 51 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
regulation of rna metabolic process GO:0051252 391 0.028
rna biosynthetic process GO:0032774 380 0.028
brain development GO:0007420 247 0.028
response to peptide GO:1901652 292 0.028
regulation of neurogenesis GO:0050767 247 0.027
neuron development GO:0048666 286 0.027
cellular amine metabolic process GO:0044106 38 0.027
cellular homeostasis GO:0019725 252 0.027
amine metabolic process GO:0009308 38 0.027
cation transport GO:0006812 382 0.027
response to inorganic substance GO:0010035 377 0.026
nitrogen compound transport GO:0071705 229 0.026
cellular component assembly GO:0022607 360 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
single organism reproductive process GO:0044702 297 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
single organism biosynthetic process GO:0044711 342 0.026
positive regulation of nervous system development GO:0051962 178 0.025
response to acid chemical GO:0001101 222 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
response to peptide hormone GO:0043434 278 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
single organism catabolic process GO:0044712 283 0.024
macromolecule localization GO:0033036 252 0.024
neurological system process GO:0050877 219 0.024
transmembrane transport GO:0055085 412 0.024
programmed cell death GO:0012501 392 0.024
positive regulation of developmental process GO:0051094 283 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
secretion by cell GO:0032940 248 0.024
homeostatic process GO:0042592 331 0.024
secretion GO:0046903 307 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
regulation of hormone levels GO:0010817 187 0.024
organophosphate metabolic process GO:0019637 370 0.023
multicellular organism reproduction GO:0032504 233 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
protein phosphorylation GO:0006468 345 0.023
protein complex subunit organization GO:0071822 302 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
nucleotide metabolic process GO:0009117 279 0.023
regulation of programmed cell death GO:0043067 341 0.023
apoptotic process GO:0006915 381 0.023
regulation of apoptotic process GO:0042981 335 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
macromolecular complex assembly GO:0065003 273 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
protein complex assembly GO:0006461 263 0.022
catabolic process GO:0009056 351 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
regulation of neuron differentiation GO:0045664 208 0.022
ion transmembrane transport GO:0034220 365 0.022
cellular response to stress GO:0033554 269 0.022
blood circulation GO:0008015 183 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
cell cell signaling GO:0007267 335 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
rhythmic process GO:0048511 156 0.022
positive regulation of neurogenesis GO:0050769 165 0.021
response to growth factor GO:0070848 189 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
protein complex biogenesis GO:0070271 263 0.021
oxidation reduction process GO:0055114 304 0.021
regulation of cellular localization GO:0060341 263 0.021
lipid metabolic process GO:0006629 283 0.021
regulation of cell proliferation GO:0042127 359 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
response to glucocorticoid GO:0051384 223 0.020
positive regulation of gene expression GO:0010628 244 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
regulation of cellular component organization GO:0051128 368 0.020
multi organism reproductive process GO:0044703 262 0.020
cellular chemical homeostasis GO:0055082 247 0.020
response to ketone GO:1901654 182 0.020
chemical homeostasis GO:0048878 292 0.020
response to nutrient GO:0007584 248 0.020
regulation of secretion GO:0051046 224 0.019
positive regulation of molecular function GO:0044093 230 0.019
regulation of molecular function GO:0065009 398 0.019
organic substance catabolic process GO:1901575 316 0.019
positive regulation of cell development GO:0010720 176 0.019
organelle organization GO:0006996 266 0.019
regulation of phosphorylation GO:0042325 248 0.019
regulation of cell projection organization GO:0031344 175 0.019
regulation of cell development GO:0060284 263 0.019
positive regulation of transport GO:0051050 245 0.019
negative regulation of gene expression GO:0010629 199 0.019
female pregnancy GO:0007565 122 0.019
small molecule biosynthetic process GO:0044283 124 0.019
protein oligomerization GO:0051259 191 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
regulation of signal transduction GO:0009966 318 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
regulation of neuron projection development GO:0010975 161 0.018
locomotion GO:0040011 237 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
response to oxygen levels GO:0070482 265 0.018
cellular lipid metabolic process GO:0044255 208 0.018
tissue development GO:0009888 252 0.018
cellular response to lipid GO:0071396 201 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
regulation of membrane potential GO:0042391 110 0.018
response to decreased oxygen levels GO:0036293 237 0.018
regulation of system process GO:0044057 208 0.017
signal release GO:0023061 145 0.017
purine containing compound metabolic process GO:0072521 253 0.017
positive regulation of signaling GO:0023056 270 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
positive regulation of cell communication GO:0010647 271 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of catalytic activity GO:0050790 304 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to carbohydrate GO:0009743 183 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
negative regulation of molecular function GO:0044092 133 0.017
regulation of peptide transport GO:0090087 87 0.017
anion transport GO:0006820 178 0.017
developmental process involved in reproduction GO:0003006 159 0.017
non canonical wnt signaling pathway GO:0035567 3 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
regulation of synaptic transmission GO:0050804 141 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
axon development GO:0061564 96 0.017
lipid biosynthetic process GO:0008610 128 0.016
behavior GO:0007610 205 0.016
synaptic transmission GO:0007268 235 0.016
sexual reproduction GO:0019953 148 0.016
response to hypoxia GO:0001666 231 0.016
reproductive system development GO:0061458 128 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
response to glucose GO:0009749 136 0.016
amide transport GO:0042886 105 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
cell projection morphogenesis GO:0048858 123 0.016
response to corticosteroid GO:0031960 235 0.016
aging GO:0007568 241 0.016
response to hexose GO:0009746 144 0.016
neuron projection morphogenesis GO:0048812 122 0.015
growth GO:0040007 165 0.015
peptide transport GO:0015833 97 0.015
response to ethanol GO:0045471 162 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
development of primary sexual characteristics GO:0045137 107 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
organic acid biosynthetic process GO:0016053 83 0.015
cellular ion homeostasis GO:0006873 184 0.015
hormone secretion GO:0046879 115 0.015
regulation of secretion by cell GO:1903530 208 0.015
circulatory system process GO:0003013 183 0.015
metal ion transport GO:0030001 289 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
establishment of tissue polarity GO:0007164 2 0.015
regulation of ion transport GO:0043269 245 0.015
gastrulation GO:0007369 2 0.015
metal ion homeostasis GO:0055065 186 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
regulation of protein metabolic process GO:0051246 289 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
cation transmembrane transport GO:0098655 263 0.015
cellular catabolic process GO:0044248 295 0.015
heart morphogenesis GO:0003007 3 0.015
intracellular signal transduction GO:0035556 314 0.015
response to monosaccharide GO:0034284 159 0.014
protein localization GO:0008104 191 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
response to radiation GO:0009314 137 0.014
cellular component morphogenesis GO:0032989 155 0.014
response to vitamin GO:0033273 131 0.014
chromosome segregation GO:0007059 2 0.014
cellular response to peptide GO:1901653 133 0.014
positive regulation of cell death GO:0010942 184 0.014
cellular cation homeostasis GO:0030003 180 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
cell part morphogenesis GO:0032990 123 0.014
cofactor metabolic process GO:0051186 95 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
negative regulation of cell communication GO:0010648 158 0.014
response to oxidative stress GO:0006979 186 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
intracellular transport GO:0046907 185 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
peptide secretion GO:0002790 86 0.014
calcium ion homeostasis GO:0055074 162 0.014
response to wounding GO:0009611 254 0.014
positive regulation of cellular component organization GO:0051130 200 0.013
cell migration GO:0016477 197 0.013
action potential GO:0001508 54 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
localization of cell GO:0051674 202 0.013
gonad development GO:0008406 104 0.013
gland development GO:0048732 155 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
carbohydrate metabolic process GO:0005975 130 0.013
negative regulation of signaling GO:0023057 157 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.013
coenzyme metabolic process GO:0006732 86 0.013
sex differentiation GO:0007548 113 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
axis specification GO:0009798 4 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
positive regulation of signal transduction GO:0009967 175 0.013
transmission of nerve impulse GO:0019226 42 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
sulfur compound metabolic process GO:0006790 70 0.013
reproductive structure development GO:0048608 128 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
neuronal action potential GO:0019228 35 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
multicellular organismal signaling GO:0035637 44 0.013
gamete generation GO:0007276 124 0.013
nucleoside metabolic process GO:0009116 179 0.013
cation homeostasis GO:0055080 195 0.013
hormone transport GO:0009914 121 0.013
regulation of transferase activity GO:0051338 123 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
regeneration GO:0031099 163 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of peptide secretion GO:0002791 82 0.012
regulation of protein modification process GO:0031399 194 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
negative regulation of transport GO:0051051 136 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
regulation of blood circulation GO:1903522 110 0.012
ion homeostasis GO:0050801 212 0.012
protein transport GO:0015031 132 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
multicellular organism growth GO:0035264 1 0.012
axonogenesis GO:0007409 71 0.012
anterior posterior pattern specification GO:0009952 1 0.012
multi multicellular organism process GO:0044706 138 0.012
cellular response to alcohol GO:0097306 87 0.012
eye morphogenesis GO:0048592 4 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cell motility GO:0048870 202 0.012
regulation of locomotion GO:0040012 148 0.012
epithelium development GO:0060429 96 0.012
hormone metabolic process GO:0042445 69 0.012
inorganic ion transmembrane transport GO:0098660 229 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
single organism organelle organization GO:1902589 180 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
appendage morphogenesis GO:0035107 4 0.011
cellular macromolecule localization GO:0070727 122 0.011
cytoplasmic transport GO:0016482 115 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
response to cytokine GO:0034097 215 0.011
negative regulation of cell death GO:0060548 229 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
defense response GO:0006952 194 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
forebrain development GO:0030900 98 0.011
organic acid transport GO:0015849 116 0.011
positive regulation of secretion GO:0051047 140 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
regulation of kinase activity GO:0043549 117 0.011
cell growth GO:0016049 104 0.011
response to estradiol GO:0032355 164 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of hormone secretion GO:0046883 106 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
response to alkaloid GO:0043279 132 0.011
lipid storage GO:0019915 1 0.011
urogenital system development GO:0001655 78 0.011
cell cycle checkpoint GO:0000075 2 0.011
motor neuron axon guidance GO:0008045 1 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
response to external biotic stimulus GO:0043207 221 0.011
cell fate determination GO:0001709 2 0.011
divalent metal ion transport GO:0070838 132 0.011
regulation of anatomical structure size GO:0090066 135 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
chemosensory behavior GO:0007635 2 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
meiotic cell cycle process GO:1903046 3 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
peptidyl amino acid modification GO:0018193 126 0.010
regulation of insulin secretion GO:0050796 65 0.010
ovulation cycle GO:0042698 67 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
insulin secretion GO:0030073 69 0.010
positive regulation of peptide hormone secretion GO:0090277 50 0.010
heterocycle catabolic process GO:0046700 167 0.010
response to insulin GO:0032868 133 0.010
ras protein signal transduction GO:0007265 29 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
regulation of neuron death GO:1901214 115 0.010
response to toxic substance GO:0009636 133 0.010

Dner disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
sensory system disease DOID:0050155 0 0.013
disease of metabolism DOID:0014667 0 0.012
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.010