Rattus norvegicus

33 known processes

Hey1

hairy/enhancer-of-split related with YRPW motif 1

(Aliases: Herp2)

Hey1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.098
regulation of signal transduction GO:0009966 318 0.074
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.064
Human
regulation of phosphorus metabolic process GO:0051174 349 0.060
neuron differentiation GO:0030182 368 0.058
central nervous system development GO:0007417 311 0.055
regulation of phosphate metabolic process GO:0019220 349 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.050
protein phosphorylation GO:0006468 345 0.049
neuron development GO:0048666 286 0.048
cellular response to endogenous stimulus GO:0071495 377 0.048
positive regulation of phosphate metabolic process GO:0045937 262 0.046
ribonucleotide metabolic process GO:0009259 231 0.045
organic acid metabolic process GO:0006082 292 0.045
cellular response to oxygen containing compound GO:1901701 386 0.045
cellular component biogenesis GO:0044085 368 0.045
regulation of intracellular signal transduction GO:1902531 218 0.044
nucleic acid templated transcription GO:0097659 379 0.044
Human
rna metabolic process GO:0016070 406 0.043
Human
brain development GO:0007420 247 0.043
regulation of multicellular organismal development GO:2000026 376 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.041
organophosphate metabolic process GO:0019637 370 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.041
positive regulation of cellular protein metabolic process GO:0032270 167 0.040
neurological system process GO:0050877 219 0.039
carboxylic acid metabolic process GO:0019752 289 0.039
regulation of molecular function GO:0065009 398 0.039
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.039
response to inorganic substance GO:0010035 377 0.038
negative regulation of metabolic process GO:0009892 331 0.038
Human
regulation of neurogenesis GO:0050767 247 0.037
cell motility GO:0048870 202 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.037
head development GO:0060322 247 0.036
neuron projection development GO:0031175 273 0.036
regulation of rna biosynthetic process GO:2001141 381 0.036
Human
nucleotide metabolic process GO:0009117 279 0.036
purine containing compound metabolic process GO:0072521 253 0.035
cellular amine metabolic process GO:0044106 38 0.034
regulation of neuron differentiation GO:0045664 208 0.034
cell projection organization GO:0030030 302 0.034
positive regulation of molecular function GO:0044093 230 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
positive regulation of response to stimulus GO:0048584 285 0.033
cell cell signaling GO:0007267 335 0.033
regulation of cell proliferation GO:0042127 359 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
amine metabolic process GO:0009308 38 0.033
oxoacid metabolic process GO:0043436 290 0.033
locomotion GO:0040011 237 0.032
catabolic process GO:0009056 351 0.032
regulation of phosphorylation GO:0042325 248 0.032
cellular component movement GO:0006928 248 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
chemical homeostasis GO:0048878 292 0.032
positive regulation of intracellular signal transduction GO:1902533 138 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
response to extracellular stimulus GO:0009991 380 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
response to nutrient levels GO:0031667 370 0.031
regulation of nervous system development GO:0051960 264 0.031
circulatory system development GO:0072359 134 0.030
Human
negative regulation of gene expression GO:0010629 199 0.030
Human
cellular ketone metabolic process GO:0042180 51 0.030
regulation of rna metabolic process GO:0051252 391 0.030
Human
transcription dna templated GO:0006351 377 0.029
Human
cellular amino acid metabolic process GO:0006520 107 0.029
positive regulation of phosphorylation GO:0042327 177 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
regulation of catalytic activity GO:0050790 304 0.029
regulation of protein modification process GO:0031399 194 0.029
homeostatic process GO:0042592 331 0.029
regulation of cell differentiation GO:0045595 320 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
rna biosynthetic process GO:0032774 380 0.028
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
Human
regulation of apoptotic process GO:0042981 335 0.027
positive regulation of protein phosphorylation GO:0001934 135 0.027
response to metal ion GO:0010038 253 0.026
cellular response to organic cyclic compound GO:0071407 202 0.026
single organism biosynthetic process GO:0044711 342 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
Human
response to oxygen levels GO:0070482 265 0.026
regulation of purine nucleotide metabolic process GO:1900542 115 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
positive regulation of nucleotide metabolic process GO:0045981 91 0.025
regulation of transcription dna templated GO:0006355 374 0.025
Human
cell migration GO:0016477 197 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of cell projection organization GO:0031344 175 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
programmed cell death GO:0012501 392 0.025
cellular component assembly GO:0022607 360 0.025
protein oligomerization GO:0051259 191 0.024
cellular response to stress GO:0033554 269 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
response to decreased oxygen levels GO:0036293 237 0.024
regulation of cellular component organization GO:0051128 368 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
regulation of neuron projection development GO:0010975 161 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
cellular catabolic process GO:0044248 295 0.024
protein complex biogenesis GO:0070271 263 0.024
ras protein signal transduction GO:0007265 29 0.024
macromolecule localization GO:0033036 252 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
lipid metabolic process GO:0006629 283 0.023
single organism reproductive process GO:0044702 297 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
response to camp GO:0051591 91 0.022
regulation of cell development GO:0060284 263 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
Human
protein complex subunit organization GO:0071822 302 0.022
negative regulation of cell communication GO:0010648 158 0.022
Human
regulation of nucleotide metabolic process GO:0006140 117 0.022
synaptic transmission GO:0007268 235 0.022
regulation of protein phosphorylation GO:0001932 183 0.021
positive regulation of signal transduction GO:0009967 175 0.021
positive regulation of cell communication GO:0010647 271 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
regulation of protein metabolic process GO:0051246 289 0.021
cellular homeostasis GO:0019725 252 0.020
positive regulation of signaling GO:0023056 270 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
Human
localization of cell GO:0051674 202 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
response to other organism GO:0051707 220 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
response to reactive oxygen species GO:0000302 120 0.019
reproductive process GO:0022414 372 0.019
response to growth factor GO:0070848 189 0.019
mapk cascade GO:0000165 140 0.019
response to bacterium GO:0009617 200 0.019
protein complex assembly GO:0006461 263 0.019
response to purine containing compound GO:0014074 126 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
response to glucocorticoid GO:0051384 223 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
Human
organophosphate biosynthetic process GO:0090407 143 0.019
blood circulation GO:0008015 183 0.019
rhythmic process GO:0048511 156 0.019
regeneration GO:0031099 163 0.019
regulation of catabolic process GO:0009894 113 0.019
positive regulation of transcription dna templated GO:0045893 197 0.018
cellular chemical homeostasis GO:0055082 247 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
response to organophosphorus GO:0046683 102 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
Human
motor neuron axon guidance GO:0008045 1 0.018
purine containing compound catabolic process GO:0072523 138 0.018
negative regulation of developmental process GO:0051093 125 0.018
positive regulation of developmental process GO:0051094 283 0.018
cation homeostasis GO:0055080 195 0.018
anion transport GO:0006820 178 0.018
response to wounding GO:0009611 254 0.018
circulatory system process GO:0003013 183 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
response to external biotic stimulus GO:0043207 221 0.018
carboxylic acid transport GO:0046942 115 0.018
heterocycle catabolic process GO:0046700 167 0.017
tissue development GO:0009888 252 0.017
response to estrogen GO:0043627 232 0.017
aging GO:0007568 241 0.017
aromatic compound catabolic process GO:0019439 168 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
reproduction GO:0000003 245 0.017
negative regulation of nervous system development GO:0051961 79 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
regulation of tube size GO:0035150 89 0.017
regulation of transferase activity GO:0051338 123 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
gastrulation GO:0007369 2 0.017
positive regulation of cell differentiation GO:0045597 217 0.016
response to peptide hormone GO:0043434 278 0.016
response to ketone GO:1901654 182 0.016
appendage morphogenesis GO:0035107 4 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
organic substance catabolic process GO:1901575 316 0.016
tube development GO:0035295 89 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
cellular ion homeostasis GO:0006873 184 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
response to lipopolysaccharide GO:0032496 191 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
Human
negative regulation of molecular function GO:0044092 133 0.016
Human
organophosphate catabolic process GO:0046434 148 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
multi organism reproductive process GO:0044703 262 0.016
response to cytokine GO:0034097 215 0.016
response to peptide GO:1901652 292 0.016
cellular response to peptide GO:1901653 133 0.016
cellular lipid metabolic process GO:0044255 208 0.015
regulation of system process GO:0044057 208 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
regulation of membrane potential GO:0042391 110 0.015
response to nutrient GO:0007584 248 0.015
response to alkaloid GO:0043279 132 0.015
calcium ion homeostasis GO:0055074 162 0.015
cellular response to lipid GO:0071396 201 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
positive regulation of gene expression GO:0010628 244 0.015
forebrain development GO:0030900 98 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.015
proteolysis GO:0006508 175 0.015
apoptotic process GO:0006915 381 0.015
regulation of anatomical structure size GO:0090066 135 0.015
response to acid chemical GO:0001101 222 0.015
multicellular organism reproduction GO:0032504 233 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
Human
cardiovascular system development GO:0072358 134 0.015
Human
metal ion homeostasis GO:0055065 186 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
Human
single organism catabolic process GO:0044712 283 0.015
adult locomotory behavior GO:0008344 4 0.014
regulation of kinase activity GO:0043549 117 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
ion homeostasis GO:0050801 212 0.014
negative regulation of cell death GO:0060548 229 0.014
cation transport GO:0006812 382 0.014
nucleotide catabolic process GO:0009166 139 0.014
action potential GO:0001508 54 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
vasculature development GO:0001944 70 0.014
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.014
organic acid transport GO:0015849 116 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
positive regulation of kinase activity GO:0033674 77 0.014
cellular cation homeostasis GO:0030003 180 0.014
negative regulation of cell development GO:0010721 82 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
Human
macromolecular complex subunit organization GO:0043933 339 0.014
positive regulation of protein modification process GO:0031401 142 0.014
female pregnancy GO:0007565 122 0.014
response to carbohydrate GO:0009743 183 0.014
response to radiation GO:0009314 137 0.014
regulation of hormone levels GO:0010817 187 0.014
nucleoside metabolic process GO:0009116 179 0.014
cellular response to external stimulus GO:0071496 118 0.014
signal transduction by phosphorylation GO:0023014 144 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
regulation of synaptic transmission GO:0050804 141 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
rho protein signal transduction GO:0007266 11 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
Human
response to transition metal nanoparticle GO:1990267 122 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
Human
developmental process involved in reproduction GO:0003006 159 0.013
defense response GO:0006952 194 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
gland development GO:0048732 155 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
behavior GO:0007610 205 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
response to corticosteroid GO:0031960 235 0.013
maintenance of location GO:0051235 17 0.013
regulation of protein kinase activity GO:0045859 105 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
biological adhesion GO:0022610 110 0.013
negative regulation of signaling GO:0023057 157 0.013
Human
vascular process in circulatory system GO:0003018 96 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
Human
negative regulation of transport GO:0051051 136 0.013
epithelium development GO:0060429 96 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
intracellular transport GO:0046907 185 0.013
positive regulation of nervous system development GO:0051962 178 0.013
axis specification GO:0009798 4 0.013
blood vessel development GO:0001568 69 0.013
Human
gtp catabolic process GO:0006184 71 0.013
axon development GO:0061564 96 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
transmembrane transport GO:0055085 412 0.013
renal system development GO:0072001 67 0.013
cell projection morphogenesis GO:0048858 123 0.012
positive regulation of catabolic process GO:0009896 78 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
cell type specific apoptotic process GO:0097285 134 0.012
anterior posterior pattern specification GO:0009952 1 0.012
response to glucose GO:0009749 136 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
single organism intracellular transport GO:1902582 166 0.012
cell part morphogenesis GO:0032990 123 0.012
organic anion transport GO:0015711 132 0.012
cellular macromolecule localization GO:0070727 122 0.012
ion transmembrane transport GO:0034220 365 0.012
growth GO:0040007 165 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
chromosome segregation GO:0007059 2 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of nucleotide biosynthetic process GO:0030808 47 0.012
salivary gland morphogenesis GO:0007435 1 0.012
salivary gland development GO:0007431 3 0.012
immune system process GO:0002376 204 0.012
positive regulation of cell development GO:0010720 176 0.012
sensory perception GO:0007600 101 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.011
development of primary sexual characteristics GO:0045137 107 0.011
peptidyl amino acid modification GO:0018193 126 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of cell death GO:0010942 184 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
regulation of mapk cascade GO:0043408 116 0.011
cellular component morphogenesis GO:0032989 155 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
cell adhesion GO:0007155 110 0.011
response to hypoxia GO:0001666 231 0.011
neuron projection morphogenesis GO:0048812 122 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
dna metabolic process GO:0006259 96 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
actin filament based process GO:0030029 86 0.011
regulation of cell migration GO:0030334 128 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of cellular localization GO:0060341 263 0.011
cellular response to acid chemical GO:0071229 75 0.011
response to hexose GO:0009746 144 0.011
single organism cellular localization GO:1902580 102 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
single organism behavior GO:0044708 130 0.011
sex differentiation GO:0007548 113 0.011
blood vessel morphogenesis GO:0048514 58 0.011
Human
regulation of hydrolase activity GO:0051336 143 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
gamete generation GO:0007276 124 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
developmental growth GO:0048589 100 0.011
multi multicellular organism process GO:0044706 138 0.011
sexual reproduction GO:0019953 148 0.010
protein transport GO:0015031 132 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
gtp metabolic process GO:0046039 72 0.010
regulation of cellular component movement GO:0051270 150 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
Human
response to biotic stimulus GO:0009607 226 0.010
lipid storage GO:0019915 1 0.010
regulation of cell motility GO:2000145 131 0.010
response to toxic substance GO:0009636 133 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
regulation of blood circulation GO:1903522 110 0.010
cytoplasmic transport GO:0016482 115 0.010
cellular protein localization GO:0034613 122 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
response to monosaccharide GO:0034284 159 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
regulation of locomotion GO:0040012 148 0.010
guanosine containing compound catabolic process GO:1901069 71 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
taxis GO:0042330 67 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
nitrogen compound transport GO:0071705 229 0.010
heart morphogenesis GO:0003007 3 0.010
cell morphogenesis GO:0000902 142 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
transmission of nerve impulse GO:0019226 42 0.010

Hey1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cardiovascular system disease DOID:1287 0 0.012
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.011