Rattus norvegicus

133 known processes

Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

Map4k4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.208
regulation of apoptotic process GO:0042981 335 0.161
locomotion GO:0040011 237 0.148
regulation of cellular localization GO:0060341 263 0.120
cellular response to endogenous stimulus GO:0071495 377 0.118
cardiovascular system development GO:0072358 134 0.110
regulation of molecular function GO:0065009 398 0.099
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.095
cellular response to stress GO:0033554 269 0.095
vesicle mediated transport GO:0016192 181 0.093
regulation of rna metabolic process GO:0051252 391 0.092
response to inorganic substance GO:0010035 377 0.088
positive regulation of multicellular organismal process GO:0051240 387 0.088
negative regulation of signaling GO:0023057 157 0.087
nucleic acid templated transcription GO:0097659 379 0.086
establishment of protein localization GO:0045184 141 0.084
apoptotic process GO:0006915 381 0.084
organic acid metabolic process GO:0006082 292 0.080
macromolecule localization GO:0033036 252 0.080
regulation of transcription dna templated GO:0006355 374 0.077
positive regulation of cell migration GO:0030335 96 0.077
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.077
embryonic skeletal system morphogenesis GO:0048704 3 0.075
cation transport GO:0006812 382 0.074
response to cytokine GO:0034097 215 0.073
regulation of secretion GO:0051046 224 0.071
neuron development GO:0048666 286 0.071
regulation of cell proliferation GO:0042127 359 0.070
neuron projection development GO:0031175 273 0.070
cellular response to oxygen containing compound GO:1901701 386 0.070
positive regulation of cellular component movement GO:0051272 102 0.069
localization of cell GO:0051674 202 0.069
cell motility GO:0048870 202 0.068
protein transport GO:0015031 132 0.068
axon development GO:0061564 96 0.068
regulation of catalytic activity GO:0050790 304 0.068
nitrogen compound transport GO:0071705 229 0.066
response to molecule of bacterial origin GO:0002237 194 0.065
rna metabolic process GO:0016070 406 0.065
programmed cell death GO:0012501 392 0.065
taxis GO:0042330 67 0.065
secretion GO:0046903 307 0.063
reproductive process GO:0022414 372 0.062
positive regulation of programmed cell death GO:0043068 157 0.061
positive regulation of cell motility GO:2000147 97 0.061
regulation of cell cycle GO:0051726 73 0.061
positive regulation of cell death GO:0010942 184 0.059
positive regulation of cell communication GO:0010647 271 0.057
axonogenesis GO:0007409 71 0.056
neuron differentiation GO:0030182 368 0.055
regulation of cellular component organization GO:0051128 368 0.055
multicellular organism reproduction GO:0032504 233 0.055
oxoacid metabolic process GO:0043436 290 0.054
cation transmembrane transport GO:0098655 263 0.054
ion transmembrane transport GO:0034220 365 0.054
protein localization GO:0008104 191 0.053
rna biosynthetic process GO:0032774 380 0.052
negative regulation of gene expression GO:0010629 199 0.052
central nervous system development GO:0007417 311 0.052
positive regulation of nervous system development GO:0051962 178 0.050
cellular response to cytokine stimulus GO:0071345 127 0.050
cellular component assembly GO:0022607 360 0.050
choline transport GO:0015871 4 0.050
positive regulation of biosynthetic process GO:0009891 319 0.049
cellular protein localization GO:0034613 122 0.049
single organism intracellular transport GO:1902582 166 0.049
positive regulation of cell differentiation GO:0045597 217 0.049
head development GO:0060322 247 0.049
positive regulation of rna biosynthetic process GO:1902680 197 0.049
regulation of multicellular organismal development GO:2000026 376 0.048
positive regulation of signaling GO:0023056 270 0.048
motor neuron axon guidance GO:0008045 1 0.048
regulation of secretion by cell GO:1903530 208 0.047
actin crosslink formation GO:0051764 3 0.047
reproduction GO:0000003 245 0.047
response to wounding GO:0009611 254 0.047
cellular component movement GO:0006928 248 0.047
response to external biotic stimulus GO:0043207 221 0.046
response to other organism GO:0051707 220 0.046
mesoderm development GO:0007498 2 0.046
regulation of neuron differentiation GO:0045664 208 0.046
cellular component biogenesis GO:0044085 368 0.046
chemotaxis GO:0006935 66 0.046
vasculature development GO:0001944 70 0.045
regulation of nervous system development GO:0051960 264 0.045
cellular macromolecule localization GO:0070727 122 0.045
tissue development GO:0009888 252 0.045
response to lipopolysaccharide GO:0032496 191 0.044
secretion by cell GO:0032940 248 0.044
response to bacterium GO:0009617 200 0.043
carboxylic acid metabolic process GO:0019752 289 0.043
regulation of mesenchymal cell proliferation GO:0010464 4 0.043
immune system process GO:0002376 204 0.043
blood vessel development GO:0001568 69 0.042
response to biotic stimulus GO:0009607 226 0.042
regulation of cell migration GO:0030334 128 0.042
intracellular signal transduction GO:0035556 314 0.041
regulation of kinase activity GO:0043549 117 0.041
cell cycle GO:0007049 101 0.041
negative regulation of metabolic process GO:0009892 331 0.041
brain development GO:0007420 247 0.040
cellular response to growth factor stimulus GO:0071363 162 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.040
organelle organization GO:0006996 266 0.040
embryonic skeletal system development GO:0048706 3 0.040
regulation of neurogenesis GO:0050767 247 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.039
positive regulation of apoptotic process GO:0043065 154 0.039
cellular amino acid metabolic process GO:0006520 107 0.038
protein phosphorylation GO:0006468 345 0.038
regulation of locomotion GO:0040012 148 0.038
organonitrogen compound biosynthetic process GO:1901566 167 0.038
response to growth factor GO:0070848 189 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.037
positive regulation of transport GO:0051050 245 0.037
intracellular transport GO:0046907 185 0.037
regulation of rna biosynthetic process GO:2001141 381 0.037
positive regulation of signal transduction GO:0009967 175 0.036
regulation of immune system process GO:0002682 123 0.036
macromolecular complex assembly GO:0065003 273 0.035
response to oxidative stress GO:0006979 186 0.035
ras protein signal transduction GO:0007265 29 0.035
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.035
circulatory system development GO:0072359 134 0.035
sexual reproduction GO:0019953 148 0.034
positive regulation of cellular protein metabolic process GO:0032270 167 0.034
positive regulation of neuron differentiation GO:0045666 126 0.034
cell projection organization GO:0030030 302 0.034
single organism reproductive process GO:0044702 297 0.034
endocytosis GO:0006897 84 0.034
cell part morphogenesis GO:0032990 123 0.034
negative regulation of apoptotic process GO:0043066 181 0.034
muscle structure development GO:0061061 87 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
homeostatic process GO:0042592 331 0.034
anterior posterior pattern specification GO:0009952 1 0.034
growth GO:0040007 165 0.033
regulation of signal transduction GO:0009966 318 0.033
cell migration GO:0016477 197 0.033
positive regulation of gene expression GO:0010628 244 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.032
aging GO:0007568 241 0.032
transmembrane transport GO:0055085 412 0.032
cellular response to lipid GO:0071396 201 0.032
positive regulation of cell development GO:0010720 176 0.032
regulation of cell projection organization GO:0031344 175 0.032
regulation of cell growth GO:0001558 85 0.032
b cell differentiation GO:0030183 2 0.031
response to oxygen levels GO:0070482 265 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
transcription dna templated GO:0006351 377 0.031
positive regulation of cell projection organization GO:0031346 111 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
intracellular protein transport GO:0006886 79 0.031
negative regulation of rna biosynthetic process GO:1902679 118 0.031
response to alkaloid GO:0043279 132 0.030
negative regulation of developmental process GO:0051093 125 0.030
neurological system process GO:0050877 219 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
response to hypoxia GO:0001666 231 0.030
negative regulation of cell death GO:0060548 229 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
response to ketone GO:1901654 182 0.029
response to metal ion GO:0010038 253 0.029
embryonic cranial skeleton morphogenesis GO:0048701 2 0.029
nuclear transport GO:0051169 49 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
regulation of protein metabolic process GO:0051246 289 0.029
response to hydrogen peroxide GO:0042542 89 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
protein complex biogenesis GO:0070271 263 0.028
hair follicle development GO:0001942 2 0.028
coronary vasculature morphogenesis GO:0060977 3 0.028
negative regulation of molecular function GO:0044092 133 0.028
positive regulation of blood coagulation GO:0030194 4 0.028
activation of cysteine type endopeptidase activity GO:0097202 4 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
proteolysis GO:0006508 175 0.027
response to estradiol GO:0032355 164 0.027
response to extracellular stimulus GO:0009991 380 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
regeneration GO:0031099 163 0.027
positive regulation of secretion GO:0051047 140 0.027
response to nutrient levels GO:0031667 370 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
regulation of cell motility GO:2000145 131 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
angiogenesis GO:0001525 53 0.025
single organism organelle organization GO:1902589 180 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
glandular epithelial cell differentiation GO:0002067 4 0.025
single organism biosynthetic process GO:0044711 342 0.025
cell chemotaxis GO:0060326 31 0.025
positive regulation of secretion by cell GO:1903532 128 0.025
developmental growth GO:0048589 100 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
cell cycle process GO:0022402 57 0.025
dna metabolic process GO:0006259 96 0.025
anion transport GO:0006820 178 0.024
positive regulation of mapk cascade GO:0043410 92 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
hematopoietic progenitor cell differentiation GO:0002244 2 0.024
sensory organ development GO:0007423 74 0.024
positive regulation of catalytic activity GO:0043085 184 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
regulation of nucleocytoplasmic transport GO:0046822 28 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
developmental process involved in reproduction GO:0003006 159 0.023
positive regulation of developmental process GO:0051094 283 0.023
positive regulation of phosphorylation GO:0042327 177 0.022
regulation of cell development GO:0060284 263 0.022
cell adhesion GO:0007155 110 0.022
regulation of protein localization GO:0032880 81 0.022
regulation of smoothened signaling pathway GO:0008589 2 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
cellular amine metabolic process GO:0044106 38 0.022
epiboly involved in wound healing GO:0090505 2 0.022
synaptic growth at neuromuscular junction GO:0051124 1 0.022
gastrulation GO:0007369 2 0.022
regulation of protein transport GO:0051223 68 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
amine metabolic process GO:0009308 38 0.022
synaptic transmission GO:0007268 235 0.022
multi organism reproductive process GO:0044703 262 0.021
regulation of neuron projection development GO:0010975 161 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
neuron projection morphogenesis GO:0048812 122 0.021
response to ammonium ion GO:0060359 71 0.021
organic substance catabolic process GO:1901575 316 0.021
response to insulin GO:0032868 133 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
cellular ketone metabolic process GO:0042180 51 0.020
positive regulation of neuron projection development GO:0010976 99 0.020
regulation of behavior GO:0050795 61 0.020
sulfur compound metabolic process GO:0006790 70 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.020
response to nicotine GO:0035094 51 0.020
regulation of protein kinase activity GO:0045859 105 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
membrane organization GO:0061024 94 0.020
positive regulation of molecular function GO:0044093 230 0.020
cytoskeleton organization GO:0007010 111 0.020
embryonic pattern specification GO:0009880 1 0.020
mechanoreceptor differentiation GO:0042490 2 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
positive regulation of endothelial cell migration GO:0010595 4 0.020
somatic stem cell division GO:0048103 2 0.020
regulation of cell differentiation GO:0045595 320 0.020
positive regulation of ion transport GO:0043270 94 0.020
chemical homeostasis GO:0048878 292 0.020
skin morphogenesis GO:0043589 2 0.019
lipid metabolic process GO:0006629 283 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
neuron projection guidance GO:0097485 24 0.019
protein complex subunit organization GO:0071822 302 0.019
cellular homeostasis GO:0019725 252 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
cytoplasmic transport GO:0016482 115 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
regulation of ion transport GO:0043269 245 0.019
rhythmic process GO:0048511 156 0.019
hindlimb morphogenesis GO:0035137 2 0.019
response to nutrient GO:0007584 248 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
molting cycle process GO:0022404 2 0.019
lymphocyte migration GO:0072676 3 0.019
regulation of establishment of protein localization GO:0070201 69 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
protein localization to organelle GO:0033365 57 0.019
heart valve morphogenesis GO:0003179 1 0.019
response to radiation GO:0009314 137 0.019
regulation of stem cell differentiation GO:2000736 2 0.019
negative regulation of transport GO:0051051 136 0.019
reproductive structure development GO:0048608 128 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
gamete generation GO:0007276 124 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.018
cellular response to ketone GO:1901655 51 0.018
mitotic cell cycle GO:0000278 49 0.018
negative regulation of cell communication GO:0010648 158 0.018
gonad development GO:0008406 104 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
vasculogenesis GO:0001570 3 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
axis specification GO:0009798 4 0.017
regulation of cellular component movement GO:0051270 150 0.017
positive regulation of protein export from nucleus GO:0046827 3 0.017
organic anion transport GO:0015711 132 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
positive regulation of intracellular transport GO:0032388 39 0.017
behavior GO:0007610 205 0.017
regulation of transferase activity GO:0051338 123 0.017
hair cycle process GO:0022405 2 0.017
regulation of hormone secretion GO:0046883 106 0.017
regulation of vasculature development GO:1901342 44 0.017
chromosome segregation GO:0007059 2 0.016
potassium ion transport GO:0006813 97 0.016
divalent metal ion transport GO:0070838 132 0.016
positive regulation of protein modification process GO:0031401 142 0.016
regulation of mapk cascade GO:0043408 116 0.016
negative regulation of osteoblast differentiation GO:0045668 2 0.016
sequestering of metal ion GO:0051238 9 0.016
regulation of system process GO:0044057 208 0.016
cytokine mediated signaling pathway GO:0019221 43 0.016
gliogenesis GO:0042063 93 0.016
purine containing compound metabolic process GO:0072521 253 0.016
mitotic cell cycle phase transition GO:0044772 20 0.016
artery development GO:0060840 3 0.016
ossification GO:0001503 70 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
regulation of chemotaxis GO:0050920 29 0.016
cellular response to external stimulus GO:0071496 118 0.016
reproductive system development GO:0061458 128 0.016
striated muscle cell development GO:0055002 26 0.016
bmp signaling pathway GO:0030509 4 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
sex differentiation GO:0007548 113 0.016
positive regulation of growth GO:0045927 55 0.015
skeletal muscle cell differentiation GO:0035914 2 0.015
protein complex assembly GO:0006461 263 0.015
spindle organization GO:0007051 2 0.015
signal release GO:0023061 145 0.015
rho protein signal transduction GO:0007266 11 0.015
positive regulation of locomotion GO:0040017 102 0.015
regulation of protein modification process GO:0031399 194 0.015
mitotic cell cycle process GO:1903047 35 0.015
positive regulation of protein transport GO:0051222 41 0.015
cell type specific apoptotic process GO:0097285 134 0.015
calcium ion homeostasis GO:0055074 162 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
cell cycle checkpoint GO:0000075 2 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
wound healing spreading of cells GO:0044319 2 0.015
metal ion homeostasis GO:0055065 186 0.014
cellular response to alcohol GO:0097306 87 0.014
muscle system process GO:0003012 115 0.014
cell cycle g1 s phase transition GO:0044843 13 0.014
calcium ion transport GO:0006816 131 0.014
cell projection morphogenesis GO:0048858 123 0.014
regulation of endocrine process GO:0044060 21 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
neuron fate commitment GO:0048663 4 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
somatic diversification of immune receptors GO:0002200 2 0.014
response to amine GO:0014075 46 0.014
regulation of neuron death GO:1901214 115 0.014
positive regulation of intracellular protein transport GO:0090316 20 0.014
liver development GO:0001889 90 0.014
response to ethanol GO:0045471 162 0.014
spinal cord development GO:0021510 27 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
response to gamma radiation GO:0010332 24 0.014
stem cell division GO:0017145 4 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
eye morphogenesis GO:0048592 4 0.014
divalent inorganic cation transport GO:0072511 134 0.014
heart morphogenesis GO:0003007 3 0.014
anion transmembrane transport GO:0098656 77 0.014
catabolic process GO:0009056 351 0.014
amino acid transport GO:0006865 70 0.014
cell morphogenesis GO:0000902 142 0.014
female gonad development GO:0008585 53 0.014
organic acid transport GO:0015849 116 0.014
response to axon injury GO:0048678 59 0.013
regulation of intracellular transport GO:0032386 65 0.013
regulation of peptidase activity GO:0052547 55 0.013
actin filament based process GO:0030029 86 0.013
negative regulation of signal transduction GO:0009968 83 0.013
regulation of anatomical structure size GO:0090066 135 0.013
regulation of hydrolase activity GO:0051336 143 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.013
response to transforming growth factor beta GO:0071559 46 0.013
blood vessel morphogenesis GO:0048514 58 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
development of primary female sexual characteristics GO:0046545 56 0.013
response to mechanical stimulus GO:0009612 134 0.013
gland development GO:0048732 155 0.013
response to vitamin GO:0033273 131 0.013
sensory perception GO:0007600 101 0.013
response to acid chemical GO:0001101 222 0.013
positive regulation of mitochondrion organization GO:0010822 4 0.013
blood circulation GO:0008015 183 0.013
regulation of developmental growth GO:0048638 45 0.013
regulation of synaptic transmission GO:0050804 141 0.013
single organism nuclear import GO:1902593 35 0.013
immune system development GO:0002520 41 0.013
sulfur compound biosynthetic process GO:0044272 19 0.013
establishment of organelle localization GO:0051656 37 0.013
response to reactive oxygen species GO:0000302 120 0.013
regulation of endothelial cell differentiation GO:0045601 4 0.013
response to decreased oxygen levels GO:0036293 237 0.013
response to dexamethasone GO:0071548 49 0.013
regulation of growth GO:0040008 105 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
single organism behavior GO:0044708 130 0.013
spermatogenesis GO:0007283 99 0.013
wound healing GO:0042060 122 0.012
regulation of response to stress GO:0080134 126 0.012
glycosaminoglycan biosynthetic process GO:0006024 4 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
growth involved in heart morphogenesis GO:0003241 1 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
multicellular organism growth GO:0035264 1 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
morphogenesis of an epithelial sheet GO:0002011 2 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
eye development GO:0001654 50 0.012
response to corticosteroid GO:0031960 235 0.012
connective tissue development GO:0061448 33 0.012
female pregnancy GO:0007565 122 0.012
antigen receptor mediated signaling pathway GO:0050851 1 0.012
lipid biosynthetic process GO:0008610 128 0.012
single organism cellular localization GO:1902580 102 0.012
organ regeneration GO:0031100 101 0.012
response to light stimulus GO:0009416 52 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
regulation of cell cycle process GO:0010564 31 0.012
cellular catabolic process GO:0044248 295 0.012
single organism membrane organization GO:0044802 74 0.012
metal ion transport GO:0030001 289 0.012
leukocyte migration GO:0050900 38 0.012
regulation of proteolysis GO:0030162 66 0.012
lipid transport GO:0006869 61 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.011
regulation of erk1 and erk2 cascade GO:0070372 41 0.011
nucleocytoplasmic transport GO:0006913 48 0.011
hair cell differentiation GO:0035315 2 0.011
protein processing GO:0016485 68 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
response to carbohydrate GO:0009743 183 0.011
epithelial cell differentiation GO:0030855 71 0.011
cellular lipid metabolic process GO:0044255 208 0.011
epithelial cell proliferation GO:0050673 54 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
ion homeostasis GO:0050801 212 0.011
leukocyte chemotaxis GO:0030595 22 0.011
somatic cell dna recombination GO:0016444 2 0.011
mitotic spindle organization GO:0007052 2 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
renal filtration GO:0097205 10 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
molting cycle GO:0042303 3 0.011
organic hydroxy compound transport GO:0015850 77 0.011
g1 s transition of mitotic cell cycle GO:0000082 12 0.011
rna localization GO:0006403 4 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
aminoglycan biosynthetic process GO:0006023 4 0.011
cell growth GO:0016049 104 0.011
regulation of cell maturation GO:1903429 3 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
cognition GO:0050890 92 0.011
organ formation GO:0048645 3 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
muscle cell differentiation GO:0042692 52 0.011
oxidation reduction process GO:0055114 304 0.011
anatomical structure maturation GO:0071695 2 0.011
regulation of organ formation GO:0003156 2 0.010
regulation of intracellular protein transport GO:0033157 34 0.010
dephosphorylation GO:0016311 98 0.010
regulation of protein export from nucleus GO:0046825 4 0.010
organophosphate metabolic process GO:0019637 370 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
response to mineralocorticoid GO:0051385 49 0.010
response to activity GO:0014823 73 0.010
negative regulation of cell development GO:0010721 82 0.010
muscle cell development GO:0055001 26 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
dendrite development GO:0016358 72 0.010
peptide transport GO:0015833 97 0.010
ventral spinal cord development GO:0021517 3 0.010
male gamete generation GO:0048232 99 0.010
response to toxic substance GO:0009636 133 0.010
cell differentiation involved in kidney development GO:0061005 4 0.010
heart formation GO:0060914 1 0.010

Map4k4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.013
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013