Rattus norvegicus

0 known processes

Dtx2

deltex homolog 2 (Drosophila)

Dtx2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphate metabolic process GO:0019220 349 0.099
intracellular signal transduction GO:0035556 314 0.088
regulation of programmed cell death GO:0043067 341 0.060
carboxylic acid metabolic process GO:0019752 289 0.055
negative regulation of cellular metabolic process GO:0031324 281 0.055
programmed cell death GO:0012501 392 0.050
transcription dna templated GO:0006351 377 0.046
cellular amino acid metabolic process GO:0006520 107 0.045
response to external biotic stimulus GO:0043207 221 0.043
regulation of transcription dna templated GO:0006355 374 0.043
regulation of molecular function GO:0065009 398 0.043
organic acid metabolic process GO:0006082 292 0.043
regulation of apoptotic process GO:0042981 335 0.042
regulation of rna metabolic process GO:0051252 391 0.042
protein phosphorylation GO:0006468 345 0.041
response to biotic stimulus GO:0009607 226 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.040
cellular response to oxygen containing compound GO:1901701 386 0.040
negative regulation of metabolic process GO:0009892 331 0.040
regulation of signal transduction GO:0009966 318 0.039
regulation of intracellular signal transduction GO:1902531 218 0.039
apoptotic process GO:0006915 381 0.038
nucleic acid templated transcription GO:0097659 379 0.038
rna metabolic process GO:0016070 406 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.037
response to peptide hormone GO:0043434 278 0.034
positive regulation of developmental process GO:0051094 283 0.034
regulation of cell differentiation GO:0045595 320 0.034
oxoacid metabolic process GO:0043436 290 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
purine containing compound metabolic process GO:0072521 253 0.032
regulation of catalytic activity GO:0050790 304 0.032
positive regulation of molecular function GO:0044093 230 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.031
regulation of multicellular organismal development GO:2000026 376 0.030
negative regulation of signaling GO:0023057 157 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
rna biosynthetic process GO:0032774 380 0.030
regulation of protein metabolic process GO:0051246 289 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
response to acid chemical GO:0001101 222 0.029
response to lipopolysaccharide GO:0032496 191 0.028
response to extracellular stimulus GO:0009991 380 0.028
regulation of rna biosynthetic process GO:2001141 381 0.027
ribonucleoside metabolic process GO:0009119 174 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
neuron projection development GO:0031175 273 0.027
nucleoside metabolic process GO:0009116 179 0.027
amine metabolic process GO:0009308 38 0.027
cellular response to stress GO:0033554 269 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
tissue development GO:0009888 252 0.026
response to nutrient levels GO:0031667 370 0.026
macromolecular complex subunit organization GO:0043933 339 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
glycosyl compound metabolic process GO:1901657 182 0.025
response to other organism GO:0051707 220 0.025
response to bacterium GO:0009617 200 0.025
organic substance catabolic process GO:1901575 316 0.025
response to oxygen levels GO:0070482 265 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
cellular amine metabolic process GO:0044106 38 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
response to hypoxia GO:0001666 231 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
response to inorganic substance GO:0010035 377 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
negative regulation of cell communication GO:0010648 158 0.024
ion transmembrane transport GO:0034220 365 0.024
nucleoside triphosphate catabolic process GO:0009143 123 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
organophosphate metabolic process GO:0019637 370 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
protein localization GO:0008104 191 0.023
catabolic process GO:0009056 351 0.023
positive regulation of nervous system development GO:0051962 178 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
response to cytokine GO:0034097 215 0.022
single organism intracellular transport GO:1902582 166 0.022
secretion GO:0046903 307 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
response to peptide GO:1901652 292 0.022
positive regulation of cell death GO:0010942 184 0.022
response to metal ion GO:0010038 253 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
cation transport GO:0006812 382 0.022
cellular ketone metabolic process GO:0042180 51 0.022
ribonucleoside triphosphate catabolic process GO:0009203 122 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
response to ketone GO:1901654 182 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
negative regulation of cell death GO:0060548 229 0.021
transmembrane transport GO:0055085 412 0.021
positive regulation of gene expression GO:0010628 244 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
protein transport GO:0015031 132 0.021
negative regulation of gene expression GO:0010629 199 0.021
response to nutrient GO:0007584 248 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
positive regulation of cell differentiation GO:0045597 217 0.020
negative regulation of signal transduction GO:0009968 83 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
regulation of cellular component organization GO:0051128 368 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
response to decreased oxygen levels GO:0036293 237 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
intracellular transport GO:0046907 185 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
establishment of protein localization GO:0045184 141 0.020
regulation of phosphorylation GO:0042325 248 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
aging GO:0007568 241 0.019
nucleoside catabolic process GO:0009164 126 0.019
neuron differentiation GO:0030182 368 0.019
reproductive process GO:0022414 372 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
cation transmembrane transport GO:0098655 263 0.019
cellular catabolic process GO:0044248 295 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
regulation of hydrolase activity GO:0051336 143 0.018
heterocycle catabolic process GO:0046700 167 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
cellular component biogenesis GO:0044085 368 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
organelle organization GO:0006996 266 0.018
gastrulation GO:0007369 2 0.018
ras protein signal transduction GO:0007265 29 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
protein complex subunit organization GO:0071822 302 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
purine containing compound catabolic process GO:0072523 138 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
positive regulation of cell proliferation GO:0008284 249 0.017
regulation of nervous system development GO:0051960 264 0.017
cell projection organization GO:0030030 302 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
regulation of cell development GO:0060284 263 0.017
nucleotide metabolic process GO:0009117 279 0.017
positive regulation of protein modification process GO:0031401 142 0.017
multicellular organism growth GO:0035264 1 0.017
vesicle mediated transport GO:0016192 181 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
regulation of ion transport GO:0043269 245 0.017
regulation of cell projection organization GO:0031344 175 0.017
single organism biosynthetic process GO:0044711 342 0.017
regulation of secretion by cell GO:1903530 208 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
peptidyl amino acid modification GO:0018193 126 0.016
regulation of mapk cascade GO:0043408 116 0.016
neuron development GO:0048666 286 0.016
proteolysis GO:0006508 175 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to ethanol GO:0045471 162 0.016
response to mechanical stimulus GO:0009612 134 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
regulation of cell proliferation GO:0042127 359 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
regulation of neurogenesis GO:0050767 247 0.016
negative regulation of innate immune response GO:0045824 4 0.016
positive regulation of cell development GO:0010720 176 0.015
regulation of protein modification process GO:0031399 194 0.015
cellular component morphogenesis GO:0032989 155 0.015
ion homeostasis GO:0050801 212 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cellular component assembly GO:0022607 360 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
mapk cascade GO:0000165 140 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
regulation of cellular localization GO:0060341 263 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
single organism organelle organization GO:1902589 180 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
macromolecular complex assembly GO:0065003 273 0.015
central nervous system development GO:0007417 311 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of neuron projection development GO:0010975 161 0.014
response to growth factor GO:0070848 189 0.014
organophosphate catabolic process GO:0046434 148 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
regulation of protein localization GO:0032880 81 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
regulation of kinase activity GO:0043549 117 0.014
aromatic compound catabolic process GO:0019439 168 0.014
cellular homeostasis GO:0019725 252 0.014
positive regulation of transport GO:0051050 245 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
response to temperature stimulus GO:0009266 94 0.014
positive regulation of nucleoside metabolic process GO:0045979 55 0.014
embryonic pattern specification GO:0009880 1 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
axis specification GO:0009798 4 0.014
nucleotide catabolic process GO:0009166 139 0.014
single organism reproductive process GO:0044702 297 0.013
protein oligomerization GO:0051259 191 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
cellular macromolecule localization GO:0070727 122 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of protein transport GO:0051223 68 0.013
defense response GO:0006952 194 0.013
circulatory system development GO:0072359 134 0.013
secretion by cell GO:0032940 248 0.013
positive regulation of signaling GO:0023056 270 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
cell type specific apoptotic process GO:0097285 134 0.013
cellular amide metabolic process GO:0043603 44 0.013
response to oxidative stress GO:0006979 186 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
cytoplasmic transport GO:0016482 115 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
dna metabolic process GO:0006259 96 0.012
protein complex biogenesis GO:0070271 263 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
neurological system process GO:0050877 219 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
neuron death GO:0070997 127 0.012
homeostatic process GO:0042592 331 0.012
response to wounding GO:0009611 254 0.012
cellular response to lipid GO:0071396 201 0.012
response to amine GO:0014075 46 0.012
response to alkaloid GO:0043279 132 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of anatomical structure size GO:0090066 135 0.011
response to reactive oxygen species GO:0000302 120 0.011
cellular response to peptide GO:1901653 133 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
cellular chemical homeostasis GO:0055082 247 0.011
sexual reproduction GO:0019953 148 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
protein complex assembly GO:0006461 263 0.011
cell morphogenesis GO:0000902 142 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
cellular response to alcohol GO:0097306 87 0.011
divalent inorganic cation transport GO:0072511 134 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
negative regulation of molecular function GO:0044092 133 0.011
regulation of protein kinase activity GO:0045859 105 0.011
intracellular protein transport GO:0006886 79 0.011
synaptic transmission GO:0007268 235 0.011
positive regulation of signal transduction GO:0009967 175 0.011
salivary gland development GO:0007431 3 0.011
response to glucocorticoid GO:0051384 223 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
cellular protein localization GO:0034613 122 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
locomotion GO:0040011 237 0.011
cell cell signaling GO:0007267 335 0.010
positive regulation of catabolic process GO:0009896 78 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
peptide biosynthetic process GO:0043043 3 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
anion transport GO:0006820 178 0.010
response to carbohydrate GO:0009743 183 0.010
metal ion transport GO:0030001 289 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
regulation of neuron differentiation GO:0045664 208 0.010
multi organism reproductive process GO:0044703 262 0.010
regulation of cellular component movement GO:0051270 150 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
b cell differentiation GO:0030183 2 0.010

Dtx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.012
sensory system disease DOID:0050155 0 0.010