Rattus norvegicus

0 known processes

Dusp8

dual specificity phosphatase 8

Dusp8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal development GO:2000026 376 0.060
response to inorganic substance GO:0010035 377 0.059
neuron projection development GO:0031175 273 0.057
neuron differentiation GO:0030182 368 0.055
response to nutrient levels GO:0031667 370 0.048
oxoacid metabolic process GO:0043436 290 0.048
response to extracellular stimulus GO:0009991 380 0.047
carboxylic acid metabolic process GO:0019752 289 0.045
cell projection organization GO:0030030 302 0.044
response to metal ion GO:0010038 253 0.043
intracellular signal transduction GO:0035556 314 0.043
regulation of signal transduction GO:0009966 318 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
transcription dna templated GO:0006351 377 0.041
cellular component morphogenesis GO:0032989 155 0.038
rna metabolic process GO:0016070 406 0.038
neuron development GO:0048666 286 0.037
regulation of molecular function GO:0065009 398 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
organic acid metabolic process GO:0006082 292 0.035
regulation of intracellular signal transduction GO:1902531 218 0.035
cellular response to oxygen containing compound GO:1901701 386 0.034
regulation of transcription dna templated GO:0006355 374 0.034
tissue development GO:0009888 252 0.033
cell projection morphogenesis GO:0048858 123 0.033
axon development GO:0061564 96 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
macromolecule localization GO:0033036 252 0.031
organic substance catabolic process GO:1901575 316 0.031
regulation of synaptic transmission GO:0050804 141 0.031
regulation of programmed cell death GO:0043067 341 0.030
protein phosphorylation GO:0006468 345 0.030
cellular component assembly GO:0022607 360 0.030
cellular amino acid metabolic process GO:0006520 107 0.029
catabolic process GO:0009056 351 0.029
regulation of rna biosynthetic process GO:2001141 381 0.028
negative regulation of signaling GO:0023057 157 0.028
regulation of rna metabolic process GO:0051252 391 0.028
regulation of nervous system development GO:0051960 264 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
cell part morphogenesis GO:0032990 123 0.028
regulation of catalytic activity GO:0050790 304 0.028
head development GO:0060322 247 0.028
cellular amine metabolic process GO:0044106 38 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
nucleotide metabolic process GO:0009117 279 0.027
positive regulation of molecular function GO:0044093 230 0.026
cell cell signaling GO:0007267 335 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
aging GO:0007568 241 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
cellular catabolic process GO:0044248 295 0.026
central nervous system development GO:0007417 311 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
amine metabolic process GO:0009308 38 0.025
response to peptide hormone GO:0043434 278 0.025
regulation of apoptotic process GO:0042981 335 0.025
multicellular organism reproduction GO:0032504 233 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
positive regulation of gene expression GO:0010628 244 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
response to peptide GO:1901652 292 0.024
protein localization GO:0008104 191 0.024
cellular component biogenesis GO:0044085 368 0.024
cell morphogenesis GO:0000902 142 0.024
regulation of cell differentiation GO:0045595 320 0.024
apoptotic process GO:0006915 381 0.024
positive regulation of neurogenesis GO:0050769 165 0.023
protein complex subunit organization GO:0071822 302 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
aromatic compound catabolic process GO:0019439 168 0.023
metal ion transport GO:0030001 289 0.023
nitrogen compound transport GO:0071705 229 0.023
positive regulation of developmental process GO:0051094 283 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
positive regulation of nervous system development GO:0051962 178 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
regulation of cell proliferation GO:0042127 359 0.023
programmed cell death GO:0012501 392 0.023
positive regulation of cell differentiation GO:0045597 217 0.022
regulation of cell projection organization GO:0031344 175 0.022
establishment of protein localization GO:0045184 141 0.022
reproductive process GO:0022414 372 0.022
regulation of cellular component organization GO:0051128 368 0.022
organophosphate metabolic process GO:0019637 370 0.022
nucleic acid templated transcription GO:0097659 379 0.022
positive regulation of signaling GO:0023056 270 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
macromolecular complex assembly GO:0065003 273 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
brain development GO:0007420 247 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
purine containing compound metabolic process GO:0072521 253 0.021
regulation of cell development GO:0060284 263 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
response to corticosteroid GO:0031960 235 0.021
single organism catabolic process GO:0044712 283 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
ras protein signal transduction GO:0007265 29 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
response to nutrient GO:0007584 248 0.020
anion transport GO:0006820 178 0.020
regulation of phosphorylation GO:0042325 248 0.020
cellular homeostasis GO:0019725 252 0.020
heterocycle catabolic process GO:0046700 167 0.020
behavior GO:0007610 205 0.020
positive regulation of catalytic activity GO:0043085 184 0.019
locomotion GO:0040011 237 0.019
response to glucocorticoid GO:0051384 223 0.019
cellular cation homeostasis GO:0030003 180 0.019
cellular ion homeostasis GO:0006873 184 0.019
neurological system process GO:0050877 219 0.019
regulation of secretion GO:0051046 224 0.019
positive regulation of cell communication GO:0010647 271 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
nucleoside metabolic process GO:0009116 179 0.019
multi organism reproductive process GO:0044703 262 0.019
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
single organism organelle organization GO:1902589 180 0.018
regulation of neuron projection development GO:0010975 161 0.018
regulation of ion transport GO:0043269 245 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
cell migration GO:0016477 197 0.018
reproduction GO:0000003 245 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
regulation of catabolic process GO:0009894 113 0.018
response to cytokine GO:0034097 215 0.018
cellular ketone metabolic process GO:0042180 51 0.018
single organism intracellular transport GO:1902582 166 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
response to mechanical stimulus GO:0009612 134 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
positive regulation of hydrolase activity GO:0051345 86 0.018
regulation of secretion by cell GO:1903530 208 0.018
ion transmembrane transport GO:0034220 365 0.018
regulation of protein metabolic process GO:0051246 289 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
response to acid chemical GO:0001101 222 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
cation transport GO:0006812 382 0.017
cellular chemical homeostasis GO:0055082 247 0.017
organelle organization GO:0006996 266 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
protein complex biogenesis GO:0070271 263 0.017
transmembrane transport GO:0055085 412 0.017
negative regulation of cell communication GO:0010648 158 0.017
negative regulation of developmental process GO:0051093 125 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
regulation of neurogenesis GO:0050767 247 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
regeneration GO:0031099 163 0.017
negative regulation of metabolic process GO:0009892 331 0.016
rna biosynthetic process GO:0032774 380 0.016
calcium ion homeostasis GO:0055074 162 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
ion homeostasis GO:0050801 212 0.016
regulation of hormone levels GO:0010817 187 0.016
regulation of locomotion GO:0040012 148 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
gland development GO:0048732 155 0.016
regulation of membrane potential GO:0042391 110 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
olfactory learning GO:0008355 1 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
response to decreased oxygen levels GO:0036293 237 0.016
neuron projection morphogenesis GO:0048812 122 0.015
positive regulation of cell development GO:0010720 176 0.015
sexual reproduction GO:0019953 148 0.015
regulation of protein kinase activity GO:0045859 105 0.015
response to oxidative stress GO:0006979 186 0.015
single organism biosynthetic process GO:0044711 342 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
reproductive structure development GO:0048608 128 0.015
response to wounding GO:0009611 254 0.015
cell cycle GO:0007049 101 0.015
response to organophosphorus GO:0046683 102 0.015
single organism behavior GO:0044708 130 0.015
regulation of peptide transport GO:0090087 87 0.015
organophosphate catabolic process GO:0046434 148 0.015
negative regulation of cell death GO:0060548 229 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
establishment of tissue polarity GO:0007164 2 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
cellular macromolecule localization GO:0070727 122 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
signal release GO:0023061 145 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
metal ion homeostasis GO:0055065 186 0.014
developmental process involved in reproduction GO:0003006 159 0.014
purine containing compound catabolic process GO:0072523 138 0.014
protein complex assembly GO:0006461 263 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
chemical homeostasis GO:0048878 292 0.014
nucleotide catabolic process GO:0009166 139 0.014
response to estrogen GO:0043627 232 0.014
learning or memory GO:0007611 90 0.014
positive regulation of cell death GO:0010942 184 0.014
regulation of neuron differentiation GO:0045664 208 0.014
positive regulation of signal transduction GO:0009967 175 0.014
cytoplasmic transport GO:0016482 115 0.014
chemosensory behavior GO:0007635 2 0.014
single organism reproductive process GO:0044702 297 0.014
embryonic pattern specification GO:0009880 1 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
cellular component movement GO:0006928 248 0.014
forebrain development GO:0030900 98 0.013
gastrulation GO:0007369 2 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
protein oligomerization GO:0051259 191 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
cell adhesion GO:0007155 110 0.013
organic acid transport GO:0015849 116 0.013
regulation of cellular localization GO:0060341 263 0.013
response to ketone GO:1901654 182 0.013
response to toxic substance GO:0009636 133 0.013
hormone transport GO:0009914 121 0.013
negative regulation of transport GO:0051051 136 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
synaptic transmission GO:0007268 235 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
olfactory behavior GO:0042048 2 0.013
carboxylic acid transport GO:0046942 115 0.013
cellular response to stress GO:0033554 269 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
axis specification GO:0009798 4 0.013
response to oxygen levels GO:0070482 265 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
cognition GO:0050890 92 0.013
intracellular transport GO:0046907 185 0.012
cellular protein localization GO:0034613 122 0.012
cation homeostasis GO:0055080 195 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cellular response to peptide GO:1901653 133 0.012
epithelium development GO:0060429 96 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
hormone secretion GO:0046879 115 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
reproductive system development GO:0061458 128 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
negative regulation of gene expression GO:0010629 199 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
secretion GO:0046903 307 0.012
regulation of protein modification process GO:0031399 194 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
lipid metabolic process GO:0006629 283 0.012
axonogenesis GO:0007409 71 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
response to camp GO:0051591 91 0.012
adult locomotory behavior GO:0008344 4 0.012
secretion by cell GO:0032940 248 0.012
proteolysis GO:0006508 175 0.012
biological adhesion GO:0022610 110 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
peptide transport GO:0015833 97 0.012
female pregnancy GO:0007565 122 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
negative regulation of cell development GO:0010721 82 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
regulation of peptide secretion GO:0002791 82 0.011
response to reactive oxygen species GO:0000302 120 0.011
multicellular organism growth GO:0035264 1 0.011
response to growth factor GO:0070848 189 0.011
response to hypoxia GO:0001666 231 0.011
vesicle mediated transport GO:0016192 181 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
spindle organization GO:0007051 2 0.011
response to insulin GO:0032868 133 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
growth GO:0040007 165 0.011
mitotic spindle organization GO:0007052 2 0.011
memory GO:0007613 54 0.011
regulation of kinase activity GO:0043549 117 0.011
chromosome segregation GO:0007059 2 0.011
protein heterooligomerization GO:0051291 89 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
developmental growth GO:0048589 100 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
regulation of response to external stimulus GO:0032101 106 0.011
intracellular protein transport GO:0006886 79 0.011
dna metabolic process GO:0006259 96 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
response to monosaccharide GO:0034284 159 0.011
amide transport GO:0042886 105 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of ion transport GO:0043270 94 0.011
response to external biotic stimulus GO:0043207 221 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
homeostatic process GO:0042592 331 0.010
transmission of nerve impulse GO:0019226 42 0.010
calcium ion transport GO:0006816 131 0.010
negative regulation of molecular function GO:0044092 133 0.010
gamete generation GO:0007276 124 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
amino acid transport GO:0006865 70 0.010
male gamete generation GO:0048232 99 0.010
peptidyl amino acid modification GO:0018193 126 0.010
cellular response to lipid GO:0071396 201 0.010
appendage morphogenesis GO:0035107 4 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
regulation of growth GO:0040008 105 0.010
cell motility GO:0048870 202 0.010
regulation of hydrolase activity GO:0051336 143 0.010
rho protein signal transduction GO:0007266 11 0.010
neuromuscular process GO:0050905 2 0.010
positive regulation of transport GO:0051050 245 0.010
action potential GO:0001508 54 0.010
organic anion transport GO:0015711 132 0.010
regulation of transferase activity GO:0051338 123 0.010

Dusp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.015
disease of metabolism DOID:0014667 0 0.011
musculoskeletal system disease DOID:17 0 0.010