Rattus norvegicus

20 known processes

Mfge8

milk fat globule-EGF factor 8 protein

(Aliases: OAcGD3S,MFGME8,MFGMP-E8,AGS)

Mfge8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.305
cellular component movement GO:0006928 248 0.237
Rat
cell migration GO:0016477 197 0.237
cell motility GO:0048870 202 0.223
regulation of phosphorus metabolic process GO:0051174 349 0.215
localization of cell GO:0051674 202 0.186
programmed cell death GO:0012501 392 0.181
regulation of cellular component organization GO:0051128 368 0.167
Mouse Rat
regulation of cell motility GO:2000145 131 0.166
regulation of protein metabolic process GO:0051246 289 0.165
response to wounding GO:0009611 254 0.156
Rat
locomotion GO:0040011 237 0.155
Rat
positive regulation of biosynthetic process GO:0009891 319 0.155
intracellular signal transduction GO:0035556 314 0.136
regulation of phosphorylation GO:0042325 248 0.134
positive regulation of multicellular organismal process GO:0051240 387 0.122
regulation of cell differentiation GO:0045595 320 0.121
Rat
regulation of molecular function GO:0065009 398 0.118
response to extracellular stimulus GO:0009991 380 0.116
response to biotic stimulus GO:0009607 226 0.115
regulation of phosphate metabolic process GO:0019220 349 0.112
positive regulation of signal transduction GO:0009967 175 0.109
regulation of signal transduction GO:0009966 318 0.099
regulation of cell migration GO:0030334 128 0.093
reproductive process GO:0022414 372 0.090
multi organism reproductive process GO:0044703 262 0.090
protein phosphorylation GO:0006468 345 0.090
Rat
organelle organization GO:0006996 266 0.089
regulation of programmed cell death GO:0043067 341 0.088
tissue development GO:0009888 252 0.088
organic substance catabolic process GO:1901575 316 0.088
regulation of locomotion GO:0040012 148 0.083
Rat
positive regulation of cell communication GO:0010647 271 0.082
regulation of cell development GO:0060284 263 0.081
Rat
single organism catabolic process GO:0044712 283 0.080
neuron differentiation GO:0030182 368 0.078
Rat
anatomical structure morphogenesis GO:0009653 298 0.077
Rat
cellular response to oxygen containing compound GO:1901701 386 0.075
cellular component assembly GO:0022607 360 0.074
multicellular organism reproduction GO:0032504 233 0.074
cellular catabolic process GO:0044248 295 0.073
macromolecular complex subunit organization GO:0043933 339 0.071
positive regulation of response to stimulus GO:0048584 285 0.070
apoptotic process GO:0006915 381 0.068
cellular response to endogenous stimulus GO:0071495 377 0.068
regulation of cellular component movement GO:0051270 150 0.067
Rat
single organism biosynthetic process GO:0044711 342 0.067
homeostatic process GO:0042592 331 0.067
g protein coupled receptor signaling pathway GO:0007186 242 0.066
regulation of protein phosphorylation GO:0001932 183 0.066
positive regulation of locomotion GO:0040017 102 0.065
positive regulation of cell proliferation GO:0008284 249 0.065
response to nutrient levels GO:0031667 370 0.065
oxoacid metabolic process GO:0043436 290 0.064
positive regulation of transport GO:0051050 245 0.064
Mouse
lipid metabolic process GO:0006629 283 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.060
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
organic acid metabolic process GO:0006082 292 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.059
positive regulation of developmental process GO:0051094 283 0.059
single organism reproductive process GO:0044702 297 0.058
regulation of apoptotic process GO:0042981 335 0.057
cellular amino acid metabolic process GO:0006520 107 0.056
immune system process GO:0002376 204 0.056
regulation of catalytic activity GO:0050790 304 0.056
circulatory system process GO:0003013 183 0.055
positive regulation of phosphorus metabolic process GO:0010562 262 0.055
cellular ketone metabolic process GO:0042180 51 0.055
aging GO:0007568 241 0.053
positive regulation of molecular function GO:0044093 230 0.053
cellular component biogenesis GO:0044085 368 0.052
response to corticosteroid GO:0031960 235 0.050
single organism organelle organization GO:1902589 180 0.049
protein localization GO:0008104 191 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
regulation of cellular localization GO:0060341 263 0.047
muscle structure development GO:0061061 87 0.045
response to external biotic stimulus GO:0043207 221 0.045
protein complex subunit organization GO:0071822 302 0.043
ras protein signal transduction GO:0007265 29 0.042
regulation of multicellular organismal development GO:2000026 376 0.041
Rat
positive regulation of cell motility GO:2000147 97 0.041
cellular lipid metabolic process GO:0044255 208 0.041
response to reactive oxygen species GO:0000302 120 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
secretion GO:0046903 307 0.040
biological adhesion GO:0022610 110 0.039
cellular response to cytokine stimulus GO:0071345 127 0.039
response to lipopolysaccharide GO:0032496 191 0.039
catabolic process GO:0009056 351 0.039
neuron apoptotic process GO:0051402 88 0.039
female pregnancy GO:0007565 122 0.039
positive regulation of cell migration GO:0030335 96 0.038
cellular response to lipid GO:0071396 201 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
protein complex assembly GO:0006461 263 0.037
transcription dna templated GO:0006351 377 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.037
secretion by cell GO:0032940 248 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
cellular response to organic cyclic compound GO:0071407 202 0.036
transmembrane transport GO:0055085 412 0.036
negative regulation of programmed cell death GO:0043069 183 0.036
regulation of rna metabolic process GO:0051252 391 0.035
small gtpase mediated signal transduction GO:0007264 36 0.035
regulation of transcription dna templated GO:0006355 374 0.035
regulation of hydrolase activity GO:0051336 143 0.035
positive regulation of phosphate metabolic process GO:0045937 262 0.035
cellular macromolecule localization GO:0070727 122 0.034
cell projection organization GO:0030030 302 0.034
Rat
ion transmembrane transport GO:0034220 365 0.034
regulation of cell projection organization GO:0031344 175 0.034
Rat
response to decreased oxygen levels GO:0036293 237 0.033
response to other organism GO:0051707 220 0.033
negative regulation of cell proliferation GO:0008285 119 0.033
neuron development GO:0048666 286 0.033
Rat
positive regulation of cell differentiation GO:0045597 217 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
ribonucleotide metabolic process GO:0009259 231 0.033
vesicle mediated transport GO:0016192 181 0.032
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.032
cellular response to external stimulus GO:0071496 118 0.032
organophosphate metabolic process GO:0019637 370 0.032
response to oxidative stress GO:0006979 186 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
response to inorganic substance GO:0010035 377 0.031
macromolecule localization GO:0033036 252 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
negative regulation of apoptotic process GO:0043066 181 0.031
cellular response to nitrogen compound GO:1901699 210 0.031
positive regulation of protein modification process GO:0031401 142 0.031
cellular amine metabolic process GO:0044106 38 0.031
cell activation GO:0001775 97 0.030
response to oxygen levels GO:0070482 265 0.030
positive regulation of gene expression GO:0010628 244 0.030
positive regulation of signaling GO:0023056 270 0.030
regulation of neuron differentiation GO:0045664 208 0.030
Rat
response to peptide hormone GO:0043434 278 0.030
response to metal ion GO:0010038 253 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
blood circulation GO:0008015 183 0.029
cellular response to stress GO:0033554 269 0.029
regulation of mapk cascade GO:0043408 116 0.029
regulation of neurogenesis GO:0050767 247 0.029
Rat
response to peptide GO:1901652 292 0.029
amine metabolic process GO:0009308 38 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
behavior GO:0007610 205 0.029
Rat
protein oligomerization GO:0051259 191 0.029
cellular response to oxidative stress GO:0034599 76 0.029
purine containing compound metabolic process GO:0072521 253 0.028
cell adhesion GO:0007155 110 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
organonitrogen compound catabolic process GO:1901565 179 0.028
nucleoside triphosphate metabolic process GO:0009141 144 0.028
establishment of protein localization GO:0045184 141 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
brain development GO:0007420 247 0.027
positive regulation of protein phosphorylation GO:0001934 135 0.027
negative regulation of cell death GO:0060548 229 0.027
ribonucleoside catabolic process GO:0042454 126 0.027
synaptic transmission GO:0007268 235 0.027
macromolecular complex assembly GO:0065003 273 0.027
response to glucocorticoid GO:0051384 223 0.027
wound healing GO:0042060 122 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.026
response to growth factor GO:0070848 189 0.026
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
response to hydrogen peroxide GO:0042542 89 0.026
regulation of transferase activity GO:0051338 123 0.026
regulation of system process GO:0044057 208 0.025
central nervous system development GO:0007417 311 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
response to nutrient GO:0007584 248 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.024
negative regulation of metabolic process GO:0009892 331 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
response to cytokine GO:0034097 215 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
positive regulation of cellular component movement GO:0051272 102 0.024
cell cell signaling GO:0007267 335 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
Rat
neuron projection development GO:0031175 273 0.023
Rat
regulation of blood pressure GO:0008217 83 0.023
response to mechanical stimulus GO:0009612 134 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
regulation of protein modification process GO:0031399 194 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
regulation of nervous system development GO:0051960 264 0.022
Rat
rna metabolic process GO:0016070 406 0.022
response to organophosphorus GO:0046683 102 0.022
cellular response to reactive oxygen species GO:0034614 55 0.022
epithelium development GO:0060429 96 0.022
response to bacterium GO:0009617 200 0.021
intracellular transport GO:0046907 185 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
nucleotide metabolic process GO:0009117 279 0.021
rhythmic process GO:0048511 156 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
cation transmembrane transport GO:0098655 263 0.020
reproduction GO:0000003 245 0.020
actin cytoskeleton organization GO:0030036 73 0.020
cellular chemical homeostasis GO:0055082 247 0.020
cation transport GO:0006812 382 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
Mouse
cellular homeostasis GO:0019725 252 0.020
regulation of secretion by cell GO:1903530 208 0.020
carbohydrate metabolic process GO:0005975 130 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
regulation of small gtpase mediated signal transduction GO:0051056 48 0.020
purine containing compound catabolic process GO:0072523 138 0.019
muscle system process GO:0003012 115 0.019
developmental process involved in reproduction GO:0003006 159 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
single organism cellular localization GO:1902580 102 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
regulation of catabolic process GO:0009894 113 0.019
response to insulin GO:0032868 133 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
protein complex biogenesis GO:0070271 263 0.019
regulation of g0 to g1 transition GO:0070316 3 0.019
response to hypoxia GO:0001666 231 0.018
chemical homeostasis GO:0048878 292 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
peptidyl tyrosine modification GO:0018212 72 0.018
Rat
anion transport GO:0006820 178 0.018
multi multicellular organism process GO:0044706 138 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
response to monosaccharide GO:0034284 159 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
growth GO:0040007 165 0.018
Rat
tissue remodeling GO:0048771 40 0.018
cellular response to extracellular stimulus GO:0031668 73 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
nucleotide catabolic process GO:0009166 139 0.018
response to acid chemical GO:0001101 222 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
cytokine production GO:0001816 61 0.018
reactive nitrogen species metabolic process GO:2001057 1 0.017
regeneration GO:0031099 163 0.017
heterocycle catabolic process GO:0046700 167 0.017
defense response GO:0006952 194 0.017
proteolysis GO:0006508 175 0.017
cell cycle GO:0007049 101 0.017
learning or memory GO:0007611 90 0.017
oxidation reduction process GO:0055114 304 0.017
sexual reproduction GO:0019953 148 0.017
cellular protein localization GO:0034613 122 0.016
protein heterooligomerization GO:0051291 89 0.016
response to vitamin GO:0033273 131 0.016
response to carbohydrate GO:0009743 183 0.016
nucleoside catabolic process GO:0009164 126 0.016
aromatic compound catabolic process GO:0019439 168 0.016
gtp metabolic process GO:0046039 72 0.016
nucleoside metabolic process GO:0009116 179 0.016
ion homeostasis GO:0050801 212 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
lipid biosynthetic process GO:0008610 128 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
Mouse
response to glucose GO:0009749 136 0.016
rna biosynthetic process GO:0032774 380 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.015
regulation of kinase activity GO:0043549 117 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
metal ion transport GO:0030001 289 0.015
cognition GO:0050890 92 0.015
fatty acid metabolic process GO:0006631 99 0.015
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.015
hormone secretion GO:0046879 115 0.015
nucleic acid templated transcription GO:0097659 379 0.015
inflammatory response GO:0006954 150 0.015
cell type specific apoptotic process GO:0097285 134 0.015
regulation of ras protein signal transduction GO:0046578 45 0.015
positive regulation of nervous system development GO:0051962 178 0.015
cellular amide metabolic process GO:0043603 44 0.015
cellular cation homeostasis GO:0030003 180 0.015
response to purine containing compound GO:0014074 126 0.015
gtp catabolic process GO:0006184 71 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
head development GO:0060322 247 0.014
glycerolipid metabolic process GO:0046486 67 0.014
embryo implantation GO:0007566 15 0.014
sulfur compound metabolic process GO:0006790 70 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
Rat
reactive oxygen species metabolic process GO:0072593 37 0.014
regulation of growth GO:0040008 105 0.014
Rat
regulation of rna biosynthetic process GO:2001141 381 0.014
cytoskeleton dependent cytokinesis GO:0061640 2 0.014
regulation of synaptic transmission GO:0050804 141 0.014
negative regulation of developmental process GO:0051093 125 0.014
Rat
single organism behavior GO:0044708 130 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
Rat
response to transition metal nanoparticle GO:1990267 122 0.014
response to ethanol GO:0045471 162 0.014
response to ketone GO:1901654 182 0.014
small molecule biosynthetic process GO:0044283 124 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
mapk cascade GO:0000165 140 0.013
regulation of membrane potential GO:0042391 110 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
cation homeostasis GO:0055080 195 0.013
endocytosis GO:0006897 84 0.013
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
neurological system process GO:0050877 219 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
circulatory system development GO:0072359 134 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
positive regulation of cell development GO:0010720 176 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
Rat
regulation of neuron projection development GO:0010975 161 0.013
Rat
response to estrogen GO:0043627 232 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
membrane organization GO:0061024 94 0.013
Mouse
gamete generation GO:0007276 124 0.013
single organism cell adhesion GO:0098602 46 0.013
negative regulation of molecular function GO:0044092 133 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
muscle cell proliferation GO:0033002 84 0.012
response to estradiol GO:0032355 164 0.012
organophosphate catabolic process GO:0046434 148 0.012
platelet aggregation GO:0070527 4 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
Rat
sensory organ development GO:0007423 74 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
peptidyl amino acid modification GO:0018193 126 0.012
Rat
response to hexose GO:0009746 144 0.012
dephosphorylation GO:0016311 98 0.012
cardiovascular system development GO:0072358 134 0.012
response to cgmp GO:0070305 3 0.012
neuronal action potential GO:0019228 35 0.012
regulation of neuron death GO:1901214 115 0.012
angiogenesis GO:0001525 53 0.012
single organismal cell cell adhesion GO:0016337 42 0.011
glial cell differentiation GO:0010001 65 0.011
monosaccharide metabolic process GO:0005996 61 0.011
phospholipid metabolic process GO:0006644 61 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
cellular component morphogenesis GO:0032989 155 0.011
Rat
response to starvation GO:0042594 59 0.011
glucose metabolic process GO:0006006 52 0.011
regulation of response to wounding GO:1903034 69 0.011
metal ion homeostasis GO:0055065 186 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of cell cycle GO:0051726 73 0.011
peptide metabolic process GO:0006518 32 0.011
chemosensory behavior GO:0007635 2 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
endomembrane system organization GO:0010256 48 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
Rat
axis specification GO:0009798 4 0.011
gland development GO:0048732 155 0.011
salivary gland development GO:0007431 3 0.010
nitrogen compound transport GO:0071705 229 0.010
response to camp GO:0051591 91 0.010
action potential GO:0001508 54 0.010
regulation of protein kinase activity GO:0045859 105 0.010
cellular response to alcohol GO:0097306 87 0.010
ameboidal type cell migration GO:0001667 26 0.010
steroid metabolic process GO:0008202 73 0.010
hexose metabolic process GO:0019318 58 0.010
response to calcium ion GO:0051592 59 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
muscle cell differentiation GO:0042692 52 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.010
regulation of endocytosis GO:0030100 42 0.010
Mouse
regulation of cell growth GO:0001558 85 0.010
Rat
positive regulation of cell projection organization GO:0031346 111 0.010
divalent inorganic cation transport GO:0072511 134 0.010
negative regulation of neuron apoptotic process GO:0043524 45 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
response to toxic substance GO:0009636 133 0.010
innate immune response GO:0045087 35 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010

Mfge8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.012