Rattus norvegicus

73 known processes

Ltc4s

leukotriene C4 synthase

Ltc4s biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.135
organic acid metabolic process GO:0006082 292 0.131
carboxylic acid metabolic process GO:0019752 289 0.113
macromolecule localization GO:0033036 252 0.078
positive regulation of cell proliferation GO:0008284 249 0.073
regulation of signal transduction GO:0009966 318 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.070
homeostatic process GO:0042592 331 0.065
g protein coupled receptor signaling pathway GO:0007186 242 0.062
regulation of membrane potential GO:0042391 110 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.059
programmed cell death GO:0012501 392 0.059
regulation of phosphate metabolic process GO:0019220 349 0.058
synaptic transmission GO:0007268 235 0.058
regulation of phosphorus metabolic process GO:0051174 349 0.058
nucleoside phosphate metabolic process GO:0006753 283 0.058
cellular component assembly GO:0022607 360 0.057
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.057
organophosphate metabolic process GO:0019637 370 0.056
regulation of cell proliferation GO:0042127 359 0.055
regulation of molecular function GO:0065009 398 0.054
cell projection organization GO:0030030 302 0.054
positive regulation of phosphate metabolic process GO:0045937 262 0.051
central nervous system development GO:0007417 311 0.050
positive regulation of protein phosphorylation GO:0001934 135 0.050
metal ion transport GO:0030001 289 0.050
nitrogen compound transport GO:0071705 229 0.048
regulation of cellular localization GO:0060341 263 0.047
response to peptide GO:1901652 292 0.046
secretion by cell GO:0032940 248 0.046
positive regulation of response to stimulus GO:0048584 285 0.045
Rat
protein phosphorylation GO:0006468 345 0.045
protein complex assembly GO:0006461 263 0.044
Rat
purine containing compound metabolic process GO:0072521 253 0.044
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.043
purine nucleoside catabolic process GO:0006152 124 0.042
regulation of synaptic transmission GO:0050804 141 0.042
cellular ketone metabolic process GO:0042180 51 0.042
cellular amino acid metabolic process GO:0006520 107 0.042
glycosyl compound catabolic process GO:1901658 126 0.042
secretion GO:0046903 307 0.042
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
cellular metal ion homeostasis GO:0006875 172 0.039
negative regulation of cell proliferation GO:0008285 119 0.039
protein complex biogenesis GO:0070271 263 0.039
Rat
positive regulation of catalytic activity GO:0043085 184 0.039
anatomical structure morphogenesis GO:0009653 298 0.038
purine ribonucleotide metabolic process GO:0009150 227 0.038
cellular amine metabolic process GO:0044106 38 0.038
neuron development GO:0048666 286 0.038
anion transport GO:0006820 178 0.038
amine metabolic process GO:0009308 38 0.038
positive regulation of molecular function GO:0044093 230 0.038
regulation of secretion by cell GO:1903530 208 0.037
cell morphogenesis GO:0000902 142 0.037
neurological system process GO:0050877 219 0.037
sensory perception of pain GO:0019233 73 0.037
ribonucleoside metabolic process GO:0009119 174 0.037
purine nucleoside metabolic process GO:0042278 169 0.037
regulation of cellular component organization GO:0051128 368 0.037
nucleoside triphosphate metabolic process GO:0009141 144 0.036
positive regulation of phosphorylation GO:0042327 177 0.036
ribose phosphate metabolic process GO:0019693 235 0.035
chemical homeostasis GO:0048878 292 0.035
regulation of secretion GO:0051046 224 0.035
organophosphate catabolic process GO:0046434 148 0.035
regulation of intracellular signal transduction GO:1902531 218 0.034
response to estradiol GO:0032355 164 0.034
single organism catabolic process GO:0044712 283 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
cellular component biogenesis GO:0044085 368 0.034
Rat
response to nutrient levels GO:0031667 370 0.034
cellular component morphogenesis GO:0032989 155 0.034
ribonucleoside triphosphate metabolic process GO:0009199 141 0.034
oxoacid metabolic process GO:0043436 290 0.033
cell morphogenesis involved in differentiation GO:0000904 119 0.033
regulation of catalytic activity GO:0050790 304 0.033
regulation of programmed cell death GO:0043067 341 0.033
cellular response to oxygen containing compound GO:1901701 386 0.032
positive regulation of nucleotide metabolic process GO:0045981 91 0.032
purine ribonucleoside metabolic process GO:0046128 168 0.032
glycosyl compound metabolic process GO:1901657 182 0.032
regulation of cell differentiation GO:0045595 320 0.032
ribonucleotide metabolic process GO:0009259 231 0.031
cell activation GO:0001775 97 0.031
head development GO:0060322 247 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.030
regulation of body fluid levels GO:0050878 90 0.030
regulation of hydrolase activity GO:0051336 143 0.030
ribonucleoside catabolic process GO:0042454 126 0.030
regulation of multicellular organismal development GO:2000026 376 0.029
purine nucleotide catabolic process GO:0006195 136 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
neuron projection development GO:0031175 273 0.029
metal ion homeostasis GO:0055065 186 0.029
divalent inorganic cation transport GO:0072511 134 0.028
nucleotide metabolic process GO:0009117 279 0.028
regulation of nucleotide catabolic process GO:0030811 65 0.028
cell type specific apoptotic process GO:0097285 134 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
nucleoside metabolic process GO:0009116 179 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
peptidyl amino acid modification GO:0018193 126 0.027
growth GO:0040007 165 0.027
brain development GO:0007420 247 0.026
purine nucleoside triphosphate metabolic process GO:0009144 141 0.026
regulation of purine nucleotide metabolic process GO:1900542 115 0.026
cation homeostasis GO:0055080 195 0.026
ribonucleotide catabolic process GO:0009261 136 0.026
positive regulation of developmental process GO:0051094 283 0.025
cell cell signaling GO:0007267 335 0.025
protein complex subunit organization GO:0071822 302 0.025
Rat
apoptotic process GO:0006915 381 0.025
tissue development GO:0009888 252 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
negative regulation of metabolic process GO:0009892 331 0.025
response to wounding GO:0009611 254 0.025
nucleoside triphosphate catabolic process GO:0009143 123 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
negative regulation of cell communication GO:0010648 158 0.024
positive regulation of transport GO:0051050 245 0.024
positive regulation of signaling GO:0023056 270 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.024
behavior GO:0007610 205 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
negative regulation of signal transduction GO:0009968 83 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
single organism behavior GO:0044708 130 0.023
inflammatory response GO:0006954 150 0.023
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.023
transmembrane transport GO:0055085 412 0.023
neuron differentiation GO:0030182 368 0.023
regulation of phosphorylation GO:0042325 248 0.023
cellular chemical homeostasis GO:0055082 247 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
multi organism reproductive process GO:0044703 262 0.023
reproductive process GO:0022414 372 0.023
regulation of nucleoside metabolic process GO:0009118 66 0.022
purine nucleoside triphosphate catabolic process GO:0009146 122 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.022
divalent metal ion transport GO:0070838 132 0.022
regulation of transcription dna templated GO:0006355 374 0.022
lipid biosynthetic process GO:0008610 128 0.021
positive regulation of nervous system development GO:0051962 178 0.021
nucleotide catabolic process GO:0009166 139 0.021
purine ribonucleoside catabolic process GO:0046130 124 0.021
organic anion transport GO:0015711 132 0.021
negative regulation of signaling GO:0023057 157 0.021
cellular homeostasis GO:0019725 252 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.021
ion homeostasis GO:0050801 212 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
intracellular transport GO:0046907 185 0.020
developmental growth GO:0048589 100 0.020
defense response GO:0006952 194 0.020
Rat
lipid metabolic process GO:0006629 283 0.020
positive regulation of protein modification process GO:0031401 142 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
positive regulation of hydrolase activity GO:0051345 86 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
regulation of protein metabolic process GO:0051246 289 0.019
positive regulation of cell communication GO:0010647 271 0.019
organic substance catabolic process GO:1901575 316 0.019
cation transmembrane transport GO:0098655 263 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
positive regulation of cell death GO:0010942 184 0.019
regulation of cell development GO:0060284 263 0.019
response to inorganic substance GO:0010035 377 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
response to peptide hormone GO:0043434 278 0.018
transcription dna templated GO:0006351 377 0.018
cellular response to lipid GO:0071396 201 0.018
multicellular organism growth GO:0035264 1 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
reproduction GO:0000003 245 0.018
positive regulation of nucleoside metabolic process GO:0045979 55 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
protein localization GO:0008104 191 0.018
positive regulation of cell development GO:0010720 176 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
macromolecular complex assembly GO:0065003 273 0.018
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
rna biosynthetic process GO:0032774 380 0.017
negative regulation of response to external stimulus GO:0032102 37 0.017
liver development GO:0001889 90 0.017
response to ethanol GO:0045471 162 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
response to corticosteroid GO:0031960 235 0.017
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.017
response to extracellular stimulus GO:0009991 380 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
positive regulation of gene expression GO:0010628 244 0.017
circulatory system process GO:0003013 183 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
cellular response to external stimulus GO:0071496 118 0.017
negative regulation of cell death GO:0060548 229 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
negative regulation of developmental process GO:0051093 125 0.016
protein transport GO:0015031 132 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
Rat
response to mineralocorticoid GO:0051385 49 0.016
positive regulation of gtp catabolic process GO:0033126 48 0.016
regulation of hormone levels GO:0010817 187 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
rna metabolic process GO:0016070 406 0.016
cellular ion homeostasis GO:0006873 184 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
cellular lipid metabolic process GO:0044255 208 0.016
positive regulation of cellular catabolic process GO:0031331 71 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
regulation of apoptotic process GO:0042981 335 0.016
locomotion GO:0040011 237 0.016
cellular catabolic process GO:0044248 295 0.015
regulation of rna metabolic process GO:0051252 391 0.015
single organism reproductive process GO:0044702 297 0.015
proteolysis GO:0006508 175 0.015
gtp metabolic process GO:0046039 72 0.015
nucleoside catabolic process GO:0009164 126 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
positive regulation of nucleotide catabolic process GO:0030813 53 0.015
response to growth factor GO:0070848 189 0.015
negative regulation of transport GO:0051051 136 0.015
neuron projection morphogenesis GO:0048812 122 0.015
regeneration GO:0031099 163 0.015
cell part morphogenesis GO:0032990 123 0.015
gtp catabolic process GO:0006184 71 0.015
gamete generation GO:0007276 124 0.015
response to glucocorticoid GO:0051384 223 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
hepaticobiliary system development GO:0061008 90 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
regulation of muscle system process GO:0090257 79 0.015
purine containing compound catabolic process GO:0072523 138 0.015
heterocycle catabolic process GO:0046700 167 0.014
response to radiation GO:0009314 137 0.014
sexual reproduction GO:0019953 148 0.014
regulation of system process GO:0044057 208 0.014
muscle contraction GO:0006936 88 0.014
positive regulation of gtpase activity GO:0043547 47 0.014
potassium ion transport GO:0006813 97 0.014
response to ketone GO:1901654 182 0.014
regulation of respiratory gaseous exchange GO:0043576 2 0.014
learning or memory GO:0007611 90 0.014
regulation of anatomical structure size GO:0090066 135 0.014
rhythmic process GO:0048511 156 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
axon development GO:0061564 96 0.014
catabolic process GO:0009056 351 0.014
muscle system process GO:0003012 115 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
hormone transport GO:0009914 121 0.014
sensory perception GO:0007600 101 0.014
regulation of kinase activity GO:0043549 117 0.014
response to acid chemical GO:0001101 222 0.014
positive regulation of ion transport GO:0043270 94 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
single organism intracellular transport GO:1902582 166 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
negative regulation of gene expression GO:0010629 199 0.014
regulation of homeostatic process GO:0032844 101 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
regulation of protein modification process GO:0031399 194 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
guanosine containing compound metabolic process GO:1901068 74 0.013
aromatic compound catabolic process GO:0019439 168 0.013
nucleic acid templated transcription GO:0097659 379 0.013
hormone secretion GO:0046879 115 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
regulation of response to external stimulus GO:0032101 106 0.013
Rat
organelle organization GO:0006996 266 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
calcium ion homeostasis GO:0055074 162 0.013
aging GO:0007568 241 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
guanosine containing compound catabolic process GO:1901069 71 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
positive regulation of protein tyrosine kinase activity GO:0061098 2 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of ion transport GO:0043269 245 0.013
positive regulation of signal transduction GO:0009967 175 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
positive regulation of neuron projection development GO:0010976 99 0.012
response to hexose GO:0009746 144 0.012
protein homooligomerization GO:0051260 91 0.012
Rat
regulation of response to wounding GO:1903034 69 0.012
Rat
calcium ion transport GO:0006816 131 0.012
axis specification GO:0009798 4 0.012
cellular component movement GO:0006928 248 0.012
regulation of neurogenesis GO:0050767 247 0.012
response to estrogen GO:0043627 232 0.012
organic acid transport GO:0015849 116 0.012
blood circulation GO:0008015 183 0.012
carboxylic acid transport GO:0046942 115 0.012
hepatocyte proliferation GO:0072574 3 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
ion transmembrane transport GO:0034220 365 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
astrocyte activation GO:0048143 4 0.011
cation transport GO:0006812 382 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
positive regulation of blood circulation GO:1903524 65 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
protein oligomerization GO:0051259 191 0.011
Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.011
lipid transport GO:0006869 61 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
localization of cell GO:0051674 202 0.011
cellular response to oxidative stress GO:0034599 76 0.011
organ formation GO:0048645 3 0.011
establishment of protein localization GO:0045184 141 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of transferase activity GO:0051338 123 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
response to temperature stimulus GO:0009266 94 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
response to axon injury GO:0048678 59 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
carbohydrate metabolic process GO:0005975 130 0.010
heart process GO:0003015 57 0.010
atp metabolic process GO:0046034 72 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
positive regulation of kinase activity GO:0033674 77 0.010
regulation of organelle organization GO:0033043 80 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
cellular macromolecule localization GO:0070727 122 0.010
multi multicellular organism process GO:0044706 138 0.010
muscle cell proliferation GO:0033002 84 0.010
positive regulation of transferase activity GO:0051347 81 0.010

Ltc4s disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.013