Rattus norvegicus

32 known processes

Ivd

isovaleryl coenzyme A dehydrogenase

Ivd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sulfur compound biosynthetic process GO:0044272 19 0.584
lipid metabolic process GO:0006629 283 0.324
branched chain amino acid catabolic process GO:0009083 4 0.293
organic acid metabolic process GO:0006082 292 0.215
carboxylic acid metabolic process GO:0019752 289 0.210
oxoacid metabolic process GO:0043436 290 0.181
coenzyme metabolic process GO:0006732 86 0.171
cellular amino acid metabolic process GO:0006520 107 0.167
sulfur compound metabolic process GO:0006790 70 0.160
response to nutrient GO:0007584 248 0.159
fatty acid metabolic process GO:0006631 99 0.139
acyl coa metabolic process GO:0006637 28 0.120
single organism biosynthetic process GO:0044711 342 0.119
catabolic process GO:0009056 351 0.116
organophosphate metabolic process GO:0019637 370 0.110
oxidation reduction process GO:0055114 304 0.106
protein homooligomerization GO:0051260 91 0.105
response to nutrient levels GO:0031667 370 0.094
cofactor metabolic process GO:0051186 95 0.092
cofactor biosynthetic process GO:0051188 28 0.086
cellular response to endogenous stimulus GO:0071495 377 0.078
cellular homeostasis GO:0019725 252 0.077
organic substance catabolic process GO:1901575 316 0.071
positive regulation of multicellular organismal process GO:0051240 387 0.069
protein complex subunit organization GO:0071822 302 0.069
organic acid biosynthetic process GO:0016053 83 0.069
rna metabolic process GO:0016070 406 0.067
protein phosphorylation GO:0006468 345 0.067
regulation of molecular function GO:0065009 398 0.066
cellular component biogenesis GO:0044085 368 0.065
carbohydrate derivative metabolic process GO:1901135 346 0.064
apoptotic process GO:0006915 381 0.063
carboxylic acid biosynthetic process GO:0046394 83 0.062
cellular amino acid catabolic process GO:0009063 21 0.059
cellular chemical homeostasis GO:0055082 247 0.057
hepaticobiliary system development GO:0061008 90 0.057
protein complex biogenesis GO:0070271 263 0.055
response to extracellular stimulus GO:0009991 380 0.054
carbohydrate metabolic process GO:0005975 130 0.054
regulation of rna metabolic process GO:0051252 391 0.054
chemical homeostasis GO:0048878 292 0.053
organonitrogen compound biosynthetic process GO:1901566 167 0.051
inorganic ion transmembrane transport GO:0098660 229 0.051
cellular catabolic process GO:0044248 295 0.051
response to camp GO:0051591 91 0.049
urogenital system development GO:0001655 78 0.048
regulation of neurogenesis GO:0050767 247 0.048
cellular response to stress GO:0033554 269 0.048
transcription dna templated GO:0006351 377 0.046
positive regulation of transport GO:0051050 245 0.045
cellular cation homeostasis GO:0030003 180 0.045
brain development GO:0007420 247 0.045
response to organophosphorus GO:0046683 102 0.045
response to purine containing compound GO:0014074 126 0.045
protein oligomerization GO:0051259 191 0.044
thioester metabolic process GO:0035383 28 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
response to inorganic substance GO:0010035 377 0.043
central nervous system development GO:0007417 311 0.043
nucleic acid templated transcription GO:0097659 379 0.042
macromolecule localization GO:0033036 252 0.042
programmed cell death GO:0012501 392 0.040
fatty acid oxidation GO:0019395 29 0.040
macromolecular complex subunit organization GO:0043933 339 0.040
cellular component assembly GO:0022607 360 0.040
cellular amine metabolic process GO:0044106 38 0.040
cytosolic calcium ion homeostasis GO:0051480 140 0.039
regulation of phosphorylation GO:0042325 248 0.039
cellular response to hormone stimulus GO:0032870 247 0.039
purine containing compound metabolic process GO:0072521 253 0.039
cellular response to lipid GO:0071396 201 0.039
homeostatic process GO:0042592 331 0.039
cellular response to oxygen containing compound GO:1901701 386 0.038
rna biosynthetic process GO:0032774 380 0.038
ion homeostasis GO:0050801 212 0.038
single organism reproductive process GO:0044702 297 0.037
response to hypoxia GO:0001666 231 0.037
response to oxygen levels GO:0070482 265 0.037
response to ketone GO:1901654 182 0.037
response to acid chemical GO:0001101 222 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
cellular ketone metabolic process GO:0042180 51 0.035
response to glucocorticoid GO:0051384 223 0.035
macromolecular complex assembly GO:0065003 273 0.034
nucleotide metabolic process GO:0009117 279 0.033
cellular response to organonitrogen compound GO:0071417 197 0.033
cellular lipid metabolic process GO:0044255 208 0.033
regulation of transcription dna templated GO:0006355 374 0.032
anion transport GO:0006820 178 0.032
cellular carbohydrate metabolic process GO:0044262 72 0.031
head development GO:0060322 247 0.031
ion transmembrane transport GO:0034220 365 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
nitrogen compound transport GO:0071705 229 0.031
response to ethanol GO:0045471 162 0.030
positive regulation of nervous system development GO:0051962 178 0.030
inorganic cation transmembrane transport GO:0098662 202 0.030
protein complex assembly GO:0006461 263 0.029
cation homeostasis GO:0055080 195 0.029
protein homotetramerization GO:0051289 25 0.029
reproductive process GO:0022414 372 0.029
nucleoside metabolic process GO:0009116 179 0.028
positive regulation of cell projection organization GO:0031346 111 0.028
metal ion homeostasis GO:0055065 186 0.027
regulation of nervous system development GO:0051960 264 0.027
secretion GO:0046903 307 0.027
glycosyl compound metabolic process GO:1901657 182 0.027
calcium ion homeostasis GO:0055074 162 0.027
cellular ion homeostasis GO:0006873 184 0.027
intracellular signal transduction GO:0035556 314 0.027
positive regulation of cell development GO:0010720 176 0.026
sexual reproduction GO:0019953 148 0.026
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
regulation of cell development GO:0060284 263 0.026
regulation of neuron differentiation GO:0045664 208 0.026
negative regulation of transcription dna templated GO:0045892 116 0.025
regulation of programmed cell death GO:0043067 341 0.025
protein localization GO:0008104 191 0.025
response to alkaloid GO:0043279 132 0.025
multicellular organism reproduction GO:0032504 233 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
protein tetramerization GO:0051262 38 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
response to fatty acid GO:0070542 65 0.024
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.024
cation transport GO:0006812 382 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
response to oxidative stress GO:0006979 186 0.024
cellular response to acid chemical GO:0071229 75 0.023
regulation of signal transduction GO:0009966 318 0.023
single organism cellular localization GO:1902580 102 0.023
positive regulation of molecular function GO:0044093 230 0.023
negative regulation of metabolic process GO:0009892 331 0.022
multi organism reproductive process GO:0044703 262 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.022
small molecule biosynthetic process GO:0044283 124 0.022
response to peptide GO:1901652 292 0.022
positive regulation of developmental process GO:0051094 283 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
reproduction GO:0000003 245 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
positive regulation of neuron projection development GO:0010976 99 0.021
generation of precursor metabolites and energy GO:0006091 62 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
organelle organization GO:0006996 266 0.021
monocarboxylic acid biosynthetic process GO:0072330 48 0.021
kidney development GO:0001822 67 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
gland development GO:0048732 155 0.020
lipid biosynthetic process GO:0008610 128 0.020
regulation of homeostatic process GO:0032844 101 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
thioester biosynthetic process GO:0035384 7 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
regulation of metal ion transport GO:0010959 118 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
cellular response to drug GO:0035690 30 0.019
positive regulation of signaling GO:0023056 270 0.019
tissue development GO:0009888 252 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
forebrain development GO:0030900 98 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
maintenance of location GO:0051235 17 0.019
regulation of cell proliferation GO:0042127 359 0.019
branched chain amino acid metabolic process GO:0009081 4 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
response to metal ion GO:0010038 253 0.019
regulation of cell differentiation GO:0045595 320 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
response to lipopolysaccharide GO:0032496 191 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
aging GO:0007568 241 0.018
regulation of protein metabolic process GO:0051246 289 0.018
negative regulation of cell death GO:0060548 229 0.018
pyruvate metabolic process GO:0006090 27 0.018
regulation of ion transport GO:0043269 245 0.018
organic anion transport GO:0015711 132 0.018
cellular modified amino acid biosynthetic process GO:0042398 18 0.018
acetyl coa metabolic process GO:0006084 17 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
regulation of catalytic activity GO:0050790 304 0.018
neuron differentiation GO:0030182 368 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
response to estrogen GO:0043627 232 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.017
immune system process GO:0002376 204 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
regulation of cellular localization GO:0060341 263 0.017
neuron projection development GO:0031175 273 0.017
sequestering of metal ion GO:0051238 9 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
alpha amino acid catabolic process GO:1901606 20 0.017
response to toxic substance GO:0009636 133 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
developmental process involved in reproduction GO:0003006 159 0.017
positive regulation of ion transport GO:0043270 94 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
purine containing compound biosynthetic process GO:0072522 85 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
regulation of cell projection organization GO:0031344 175 0.016
metal ion transport GO:0030001 289 0.016
spindle organization GO:0007051 2 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
tube development GO:0035295 89 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
positive regulation of protein modification process GO:0031401 142 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
amine metabolic process GO:0009308 38 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
regulation of calcium ion transport GO:0051924 77 0.015
regulation of hormone levels GO:0010817 187 0.015
cytoplasmic transport GO:0016482 115 0.015
acetate metabolic process GO:0006083 2 0.015
blood circulation GO:0008015 183 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
neurological system process GO:0050877 219 0.015
response to decreased oxygen levels GO:0036293 237 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
negative regulation of gene expression GO:0010629 199 0.014
response to vitamin GO:0033273 131 0.014
lipid localization GO:0010876 62 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of transferase activity GO:0051338 123 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
intracellular transport GO:0046907 185 0.014
response to carbohydrate GO:0009743 183 0.014
positive regulation of gene expression GO:0010628 244 0.014
regulation of protein modification process GO:0031399 194 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
metanephric epithelium development GO:0072207 4 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
negative regulation of transport GO:0051051 136 0.014
carbohydrate catabolic process GO:0016052 40 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
cell projection organization GO:0030030 302 0.014
positive regulation of ion transmembrane transport GO:0034767 24 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
response to monosaccharide GO:0034284 159 0.013
peptidyl serine modification GO:0018209 34 0.013
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
regulation of neuron projection development GO:0010975 161 0.013
response to mechanical stimulus GO:0009612 134 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
cellular response to peptide GO:1901653 133 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
acetate biosynthetic process GO:0019413 2 0.013
glucose homeostasis GO:0042593 75 0.013
rna localization GO:0006403 4 0.013
regulation of transmembrane transport GO:0034762 122 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
divalent inorganic cation transport GO:0072511 134 0.013
eye morphogenesis GO:0048592 4 0.013
gamete generation GO:0007276 124 0.013
sequestering of calcium ion GO:0051208 8 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
calcium ion transport GO:0006816 131 0.013
behavior GO:0007610 205 0.013
single organism intracellular transport GO:1902582 166 0.013
cellular amino acid biosynthetic process GO:0008652 32 0.013
regulation of system process GO:0044057 208 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
anion transmembrane transport GO:0098656 77 0.013
amide biosynthetic process GO:0043604 10 0.012
negative regulation of signaling GO:0023057 157 0.012
carboxylic acid transport GO:0046942 115 0.012
response to wounding GO:0009611 254 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
cellular response to external stimulus GO:0071496 118 0.012
response to external biotic stimulus GO:0043207 221 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
carbohydrate homeostasis GO:0033500 75 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
metanephric tubule development GO:0072170 4 0.012
microtubule organizing center organization GO:0031023 1 0.012
purine ribonucleoside biosynthetic process GO:0046129 21 0.012
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.012
ras protein signal transduction GO:0007265 29 0.012
gastrulation GO:0007369 2 0.012
cellular macromolecule localization GO:0070727 122 0.012
glycosyl compound biosynthetic process GO:1901659 25 0.012
positive regulation of cell communication GO:0010647 271 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
positive regulation of phosphorylation GO:0042327 177 0.011
regulation of apoptotic process GO:0042981 335 0.011
regulation of coenzyme metabolic process GO:0051196 1 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to cytokine GO:0034097 215 0.011
single organism catabolic process GO:0044712 283 0.011
regulation of immune system process GO:0002682 123 0.011
heart morphogenesis GO:0003007 3 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
response to estradiol GO:0032355 164 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
type b pancreatic cell proliferation GO:0044342 3 0.011
cellular response to oxidative stress GO:0034599 76 0.011
male gamete generation GO:0048232 99 0.011
mitotic spindle organization GO:0007052 2 0.011
epithelium development GO:0060429 96 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
multi multicellular organism process GO:0044706 138 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
immune response GO:0006955 104 0.011
circulatory system process GO:0003013 183 0.011
response to genistein GO:0033595 4 0.011
glucose metabolic process GO:0006006 52 0.011
toxin catabolic process GO:0009407 1 0.011
organic hydroxy compound transport GO:0015850 77 0.011
regulation of body fluid levels GO:0050878 90 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
response to corticosteroid GO:0031960 235 0.011
regulation of catabolic process GO:0009894 113 0.011
lipid storage GO:0019915 1 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
spermatogenesis GO:0007283 99 0.011
response to amino acid GO:0043200 75 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
positive regulation of signal transduction GO:0009967 175 0.010
multicellular organismal signaling GO:0035637 44 0.010
transmission of nerve impulse GO:0019226 42 0.010
ribonucleoside diphosphate biosynthetic process GO:0009188 10 0.010
proteolysis GO:0006508 175 0.010
peptidyl amino acid modification GO:0018193 126 0.010
mesoderm development GO:0007498 2 0.010
cell migration GO:0016477 197 0.010
peptide biosynthetic process GO:0043043 3 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.010
salivary gland development GO:0007431 3 0.010
cell motility GO:0048870 202 0.010
transmembrane transport GO:0055085 412 0.010
response to hexose GO:0009746 144 0.010
negative regulation of cell communication GO:0010648 158 0.010
cytoskeleton organization GO:0007010 111 0.010

Ivd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.155
Human
amino acid metabolic disorder DOID:9252 0 0.155
Human
inherited metabolic disorder DOID:655 0 0.155
Human
organic acidemia DOID:0060159 0 0.155
Human
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013