Rattus norvegicus

20 known processes

Sdha

succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

Sdha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 304 0.845
oxoacid metabolic process GO:0043436 290 0.765
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.752
dicarboxylic acid metabolic process GO:0043648 42 0.698
citrate metabolic process GO:0006101 3 0.651
organic acid metabolic process GO:0006082 292 0.631
acetyl coa biosynthetic process GO:0006085 6 0.622
energy derivation by oxidation of organic compounds GO:0015980 46 0.621
sulfur compound biosynthetic process GO:0044272 19 0.564
coenzyme metabolic process GO:0006732 86 0.558
carboxylic acid metabolic process GO:0019752 289 0.551
acetyl coa metabolic process GO:0006084 17 0.539
acyl coa metabolic process GO:0006637 28 0.502
isocitrate metabolic process GO:0006102 5 0.460
tricarboxylic acid cycle GO:0006099 11 0.396
cellular respiration GO:0045333 21 0.396
coenzyme biosynthetic process GO:0009108 22 0.366
thioester metabolic process GO:0035383 28 0.338
cofactor metabolic process GO:0051186 95 0.326
cofactor biosynthetic process GO:0051188 28 0.323
generation of precursor metabolites and energy GO:0006091 62 0.309
aerobic respiration GO:0009060 13 0.293
single organism biosynthetic process GO:0044711 342 0.247
tricarboxylic acid metabolic process GO:0072350 10 0.209
sulfur compound metabolic process GO:0006790 70 0.190
cellular amino acid catabolic process GO:0009063 21 0.183
thioester biosynthetic process GO:0035384 7 0.138
acyl coa biosynthetic process GO:0071616 7 0.104
branched chain amino acid catabolic process GO:0009083 4 0.095
cellular amino acid metabolic process GO:0006520 107 0.090
nucleotide metabolic process GO:0009117 279 0.085
Yeast
homeostatic process GO:0042592 331 0.081
regulation of membrane potential GO:0042391 110 0.079
pyruvate metabolic process GO:0006090 27 0.079
nadh metabolic process GO:0006734 10 0.075
cellular response to oxidative stress GO:0034599 76 0.075
adp biosynthetic process GO:0006172 8 0.069
positive regulation of molecular function GO:0044093 230 0.064
response to oxidative stress GO:0006979 186 0.064
purine nucleoside diphosphate biosynthetic process GO:0009136 9 0.056
carbohydrate derivative metabolic process GO:1901135 346 0.056
Yeast
response to extracellular stimulus GO:0009991 380 0.054
regulation of protein metabolic process GO:0051246 289 0.053
reactive oxygen species metabolic process GO:0072593 37 0.053
glycosyl compound metabolic process GO:1901657 182 0.053
Yeast
regulation of molecular function GO:0065009 398 0.050
malate metabolic process GO:0006108 5 0.048
negative regulation of phosphate metabolic process GO:0045936 80 0.043
2 oxoglutarate metabolic process GO:0006103 6 0.043
neuron apoptotic process GO:0051402 88 0.043
regulation of phosphate metabolic process GO:0019220 349 0.043
regulation of neuron apoptotic process GO:0043523 83 0.042
developmental process involved in reproduction GO:0003006 159 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.041
Yeast
oxaloacetate metabolic process GO:0006107 6 0.039
catabolic process GO:0009056 351 0.038
nicotinamide nucleotide metabolic process GO:0046496 28 0.036
lipid localization GO:0010876 62 0.035
transcription dna templated GO:0006351 377 0.035
alpha amino acid catabolic process GO:1901606 20 0.035
nad metabolic process GO:0019674 15 0.034
mitochondrion organization GO:0007005 35 0.034
regulation of transferase activity GO:0051338 123 0.034
negative regulation of cellular protein metabolic process GO:0032269 106 0.034
response to alkaloid GO:0043279 132 0.033
oxidoreduction coenzyme metabolic process GO:0006733 31 0.033
response to molecule of bacterial origin GO:0002237 194 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
organophosphate metabolic process GO:0019637 370 0.033
Yeast
atp synthesis coupled electron transport GO:0042773 2 0.033
Yeast
ribonucleoside metabolic process GO:0009119 174 0.033
Yeast
cellular component biogenesis GO:0044085 368 0.033
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.032
growth GO:0040007 165 0.032
atp metabolic process GO:0046034 72 0.030
Yeast
branched chain amino acid metabolic process GO:0009081 4 0.030
negative regulation of neuron apoptotic process GO:0043524 45 0.030
ribonucleoside diphosphate biosynthetic process GO:0009188 10 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.029
Yeast
single organism catabolic process GO:0044712 283 0.029
alpha amino acid metabolic process GO:1901605 71 0.029
cellular ketone metabolic process GO:0042180 51 0.029
reproductive process GO:0022414 372 0.029
response to lipopolysaccharide GO:0032496 191 0.029
regulation of kinase activity GO:0043549 117 0.028
regulation of protein maturation GO:1903317 50 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
chemical homeostasis GO:0048878 292 0.027
organophosphate biosynthetic process GO:0090407 143 0.026
rna metabolic process GO:0016070 406 0.026
regulation of catalytic activity GO:0050790 304 0.026
regulation of hydrolase activity GO:0051336 143 0.026
protein processing GO:0016485 68 0.025
hematopoietic or lymphoid organ development GO:0048534 36 0.025
reproductive structure development GO:0048608 128 0.025
multi multicellular organism process GO:0044706 138 0.025
regulation of rna biosynthetic process GO:2001141 381 0.024
vesicle mediated transport GO:0016192 181 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of secretion by cell GO:1903532 128 0.024
aging GO:0007568 241 0.023
nucleic acid templated transcription GO:0097659 379 0.023
anion transport GO:0006820 178 0.023
negative regulation of phosphorus metabolic process GO:0010563 80 0.023
endocytosis GO:0006897 84 0.023
organic anion transport GO:0015711 132 0.023
purine nucleoside metabolic process GO:0042278 169 0.022
Yeast
ribonucleotide metabolic process GO:0009259 231 0.022
Yeast
regulation of secretion GO:0051046 224 0.022
ribonucleotide biosynthetic process GO:0009260 85 0.022
rna biosynthetic process GO:0032774 380 0.022
organic substance catabolic process GO:1901575 316 0.022
spindle organization GO:0007051 2 0.021
regulation of apoptotic process GO:0042981 335 0.021
electron transport chain GO:0022900 5 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
regulation of transcription dna templated GO:0006355 374 0.020
pyridine nucleotide metabolic process GO:0019362 28 0.020
regulation of rna metabolic process GO:0051252 391 0.020
cellular homeostasis GO:0019725 252 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
Yeast
cellular response to reactive oxygen species GO:0034614 55 0.020
peptide transport GO:0015833 97 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
aspartate family amino acid biosynthetic process GO:0009067 4 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
purine ribonucleoside diphosphate metabolic process GO:0009179 9 0.019
macromolecule localization GO:0033036 252 0.019
immune system process GO:0002376 204 0.019
regulation of peptide transport GO:0090087 87 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.019
response to nutrient levels GO:0031667 370 0.019
nucleoside monophosphate biosynthetic process GO:0009124 28 0.019
negative regulation of cell death GO:0060548 229 0.019
organic hydroxy compound biosynthetic process GO:1901617 51 0.018
cell redox homeostasis GO:0045454 1 0.018
small molecule biosynthetic process GO:0044283 124 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
regulation of growth GO:0040008 105 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
progesterone biosynthetic process GO:0006701 3 0.017
response to inorganic substance GO:0010035 377 0.017
positive regulation of cell communication GO:0010647 271 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
regulation of cysteine type endopeptidase activity GO:2000116 32 0.017
protein complex subunit organization GO:0071822 302 0.017
ribonucleoside monophosphate metabolic process GO:0009161 88 0.017
Yeast
macromolecular complex assembly GO:0065003 273 0.017
programmed cell death GO:0012501 392 0.017
response to reactive oxygen species GO:0000302 120 0.017
cellular ion homeostasis GO:0006873 184 0.017
positive regulation of protein metabolic process GO:0051247 178 0.016
central nervous system development GO:0007417 311 0.016
cellular response to stress GO:0033554 269 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
circulatory system development GO:0072359 134 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
multi organism reproductive process GO:0044703 262 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
regulation of cell proliferation GO:0042127 359 0.016
purine containing compound metabolic process GO:0072521 253 0.016
Yeast
receptor mediated endocytosis GO:0006898 42 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
cellular amine metabolic process GO:0044106 38 0.015
neuron death GO:0070997 127 0.015
sexual reproduction GO:0019953 148 0.015
lipid storage GO:0019915 1 0.015
negative regulation of neuron death GO:1901215 69 0.015
heart morphogenesis GO:0003007 3 0.015
regulation of cell differentiation GO:0045595 320 0.015
regulation of programmed cell death GO:0043067 341 0.014
single organism reproductive process GO:0044702 297 0.014
dicarboxylic acid catabolic process GO:0043649 1 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
Yeast
macromolecular complex subunit organization GO:0043933 339 0.014
reproduction GO:0000003 245 0.014
response to nutrient GO:0007584 248 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
mitochondrial rna metabolic process GO:0000959 1 0.014
carbohydrate metabolic process GO:0005975 130 0.014
microtubule organizing center organization GO:0031023 1 0.014
metanephric tubule development GO:0072170 4 0.014
cellular chemical homeostasis GO:0055082 247 0.014
response to toxic substance GO:0009636 133 0.014
response to other organism GO:0051707 220 0.013
regulation of signal transduction GO:0009966 318 0.013
adp metabolic process GO:0046031 8 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
proteolysis GO:0006508 175 0.013
female pregnancy GO:0007565 122 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
intracellular signal transduction GO:0035556 314 0.013
hormone secretion GO:0046879 115 0.013
alcohol biosynthetic process GO:0046165 38 0.013
reproductive system development GO:0061458 128 0.013
connective tissue development GO:0061448 33 0.013
regulation of cellular localization GO:0060341 263 0.013
peptidyl amino acid modification GO:0018193 126 0.013
regulation of homeostatic process GO:0032844 101 0.013
pyridine containing compound metabolic process GO:0072524 32 0.013
ion homeostasis GO:0050801 212 0.013
cellular component assembly GO:0022607 360 0.013
regulation of peptide secretion GO:0002791 82 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
negative regulation of kinase activity GO:0033673 27 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
Yeast
negative regulation of protein processing GO:0010955 47 0.012
secretion GO:0046903 307 0.012
apoptotic process GO:0006915 381 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of hormone secretion GO:0046883 106 0.012
negative regulation of metabolic process GO:0009892 331 0.012
myeloid cell differentiation GO:0030099 22 0.012
negative regulation of gene expression GO:0010629 199 0.012
negative regulation of endopeptidase activity GO:0010951 36 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
purine ribonucleoside biosynthetic process GO:0046129 21 0.012
male gamete generation GO:0048232 99 0.012
head development GO:0060322 247 0.012
regulation of protein processing GO:0070613 50 0.012
neurotransmitter uptake GO:0001504 3 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
regulation of endopeptidase activity GO:0052548 51 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of nervous system development GO:0051960 264 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
mitotic spindle organization GO:0007052 2 0.011
nucleoside metabolic process GO:0009116 179 0.011
Yeast
glycogen metabolic process GO:0005977 23 0.011
immune response to tumor cell GO:0002418 3 0.011
response to tumor cell GO:0002347 4 0.011
gamete generation GO:0007276 124 0.011
cell cell signaling GO:0007267 335 0.011
placenta development GO:0001890 22 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
single organism organelle organization GO:1902589 180 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
cation homeostasis GO:0055080 195 0.010
tissue development GO:0009888 252 0.010
response to external biotic stimulus GO:0043207 221 0.010
intracellular transport GO:0046907 185 0.010
negative regulation of protein maturation GO:1903318 47 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
Yeast
organonitrogen compound biosynthetic process GO:1901566 167 0.010
regulation of peptidase activity GO:0052547 55 0.010
protein complex biogenesis GO:0070271 263 0.010
cell type specific apoptotic process GO:0097285 134 0.010
cellular amide metabolic process GO:0043603 44 0.010
purine nucleoside biosynthetic process GO:0042451 21 0.010
c21 steroid hormone biosynthetic process GO:0006700 10 0.010

Sdha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.221
amino acid metabolic disorder DOID:9252 0 0.221
inherited metabolic disorder DOID:655 0 0.221
organic acidemia DOID:0060159 0 0.221
disease of anatomical entity DOID:7 0 0.118
nervous system disease DOID:863 0 0.118
retinal disease DOID:5679 0 0.103
sensory system disease DOID:0050155 0 0.103
eye and adnexa disease DOID:1492 0 0.103
eye disease DOID:5614 0 0.103
retinal degeneration DOID:8466 0 0.051
retinitis pigmentosa DOID:10584 0 0.048
maple syrup urine disease DOID:9269 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015