Rattus norvegicus

0 known processes

Whsc1

Wolf-Hirschhorn syndrome candidate 1 (human)

(Aliases: RGD1565590)

Whsc1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein complex biogenesis GO:0070271 263 0.068
protein complex assembly GO:0006461 263 0.053
regulation of cellular component organization GO:0051128 368 0.053
negative regulation of cellular metabolic process GO:0031324 281 0.046
macromolecular complex assembly GO:0065003 273 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
positive regulation of developmental process GO:0051094 283 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
regulation of rna biosynthetic process GO:2001141 381 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
cellular component assembly GO:0022607 360 0.036
transcription dna templated GO:0006351 377 0.036
cellular component biogenesis GO:0044085 368 0.036
nucleic acid templated transcription GO:0097659 379 0.034
regulation of programmed cell death GO:0043067 341 0.033
negative regulation of metabolic process GO:0009892 331 0.033
regulation of protein metabolic process GO:0051246 289 0.032
rna metabolic process GO:0016070 406 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.031
regulation of cell differentiation GO:0045595 320 0.031
macromolecule localization GO:0033036 252 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
programmed cell death GO:0012501 392 0.030
protein complex subunit organization GO:0071822 302 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
protein localization GO:0008104 191 0.029
negative regulation of gene expression GO:0010629 199 0.028
chromosome segregation GO:0007059 2 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
neuron differentiation GO:0030182 368 0.028
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
regulation of protein modification process GO:0031399 194 0.028
regulation of molecular function GO:0065009 398 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
protein phosphorylation GO:0006468 345 0.027
regulation of cell development GO:0060284 263 0.027
regulation of rna metabolic process GO:0051252 391 0.027
regulation of cell proliferation GO:0042127 359 0.026
rna biosynthetic process GO:0032774 380 0.025
regulation of transcription dna templated GO:0006355 374 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
positive regulation of molecular function GO:0044093 230 0.025
reproductive process GO:0022414 372 0.025
neuron projection development GO:0031175 273 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
organic substance catabolic process GO:1901575 316 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
secretion GO:0046903 307 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
positive regulation of cell differentiation GO:0045597 217 0.022
apoptotic process GO:0006915 381 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
regulation of apoptotic process GO:0042981 335 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
regulation of cell projection organization GO:0031344 175 0.022
catabolic process GO:0009056 351 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
single organism organelle organization GO:1902589 180 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
meiotic cell cycle process GO:1903046 3 0.021
reproduction GO:0000003 245 0.021
cell projection organization GO:0030030 302 0.020
cellular amine metabolic process GO:0044106 38 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
cellular ketone metabolic process GO:0042180 51 0.020
organelle organization GO:0006996 266 0.020
multi organism reproductive process GO:0044703 262 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
negative regulation of cell death GO:0060548 229 0.019
cell cycle checkpoint GO:0000075 2 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of phosphorylation GO:0042325 248 0.019
neuron development GO:0048666 286 0.018
aging GO:0007568 241 0.018
regulation of catalytic activity GO:0050790 304 0.018
positive regulation of cell death GO:0010942 184 0.018
proteolysis GO:0006508 175 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
positive regulation of gene expression GO:0010628 244 0.018
single organism catabolic process GO:0044712 283 0.018
single organism reproductive process GO:0044702 297 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
amine metabolic process GO:0009308 38 0.017
cell cell signaling GO:0007267 335 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
protein oligomerization GO:0051259 191 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of cellular localization GO:0060341 263 0.017
regulation of signal transduction GO:0009966 318 0.017
cellular response to stress GO:0033554 269 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
homeostatic process GO:0042592 331 0.016
regulation of neurogenesis GO:0050767 247 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of neuron differentiation GO:0045664 208 0.016
cellular protein localization GO:0034613 122 0.016
intracellular transport GO:0046907 185 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
positive regulation of cell development GO:0010720 176 0.016
cell cycle process GO:0022402 57 0.016
developmental process involved in reproduction GO:0003006 159 0.016
regulation of nervous system development GO:0051960 264 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
brain development GO:0007420 247 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
sister chromatid segregation GO:0000819 1 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
negative regulation of cell cycle phase transition GO:1901988 4 0.015
cellular catabolic process GO:0044248 295 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
mitotic spindle organization GO:0007052 2 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
sexual reproduction GO:0019953 148 0.014
regulation of neuron projection development GO:0010975 161 0.014
organic acid metabolic process GO:0006082 292 0.014
positive regulation of protein modification process GO:0031401 142 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
reproductive structure development GO:0048608 128 0.014
oxoacid metabolic process GO:0043436 290 0.014
cell cycle GO:0007049 101 0.014
positive regulation of transport GO:0051050 245 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
spindle organization GO:0007051 2 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
organophosphate metabolic process GO:0019637 370 0.013
nucleotide metabolic process GO:0009117 279 0.013
nitrogen compound transport GO:0071705 229 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
negative regulation of transport GO:0051051 136 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of nervous system development GO:0051962 178 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
single organism intracellular transport GO:1902582 166 0.013
negative regulation of programmed cell death GO:0043069 183 0.012
cytoskeleton organization GO:0007010 111 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
tissue development GO:0009888 252 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
rhythmic process GO:0048511 156 0.012
development of primary sexual characteristics GO:0045137 107 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
regulation of protein localization GO:0032880 81 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of membrane potential GO:0042391 110 0.012
response to external biotic stimulus GO:0043207 221 0.012
head development GO:0060322 247 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
male gamete generation GO:0048232 99 0.012
cellular response to nitrogen compound GO:1901699 210 0.011
intracellular signal transduction GO:0035556 314 0.011
establishment of protein localization GO:0045184 141 0.011
response to radiation GO:0009314 137 0.011
response to oxidative stress GO:0006979 186 0.011
sex differentiation GO:0007548 113 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
cell type specific apoptotic process GO:0097285 134 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
ion transmembrane transport GO:0034220 365 0.011
gamete generation GO:0007276 124 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
response to ketone GO:1901654 182 0.011
multicellular organism growth GO:0035264 1 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
transmembrane transport GO:0055085 412 0.011
vesicle mediated transport GO:0016192 181 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
regulation of dendrite development GO:0050773 59 0.011
response to hypoxia GO:0001666 231 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
regulation of catabolic process GO:0009894 113 0.010
regulation of cell cycle GO:0051726 73 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
response to metal ion GO:0010038 253 0.010
central nervous system development GO:0007417 311 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
response to extracellular stimulus GO:0009991 380 0.010
activation of cysteine type endopeptidase activity GO:0097202 4 0.010
nucleoside metabolic process GO:0009116 179 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular component morphogenesis GO:0032989 155 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010

Whsc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.012
sensory system disease DOID:0050155 0 0.010