|
|
histamine secretion by mast cell
|
GO:0002553 |
3 |
0.684
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.576
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.543
|
Fly |
|
|
histamine secretion involved in inflammatory response
|
GO:0002441 |
3 |
0.525
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.495
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.480
|
|
|
|
protein localization to organelle
|
GO:0033365 |
57 |
0.474
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.458
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.417
|
|
|
|
protein targeting
|
GO:0006605 |
61 |
0.412
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.397
|
|
|
|
regulation of protein phosphatase type 2a activity
|
GO:0034047 |
2 |
0.386
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.375
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.372
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.371
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
10 |
0.353
|
|
|
|
mitochondrial transport
|
GO:0006839 |
19 |
0.349
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.347
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.342
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.338
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.333
|
|
|
|
lysosome localization
|
GO:0032418 |
10 |
0.330
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.321
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
3 |
0.315
|
|
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.309
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.303
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.295
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.281
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.279
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.252
|
|
|
|
mitochondrion organization
|
GO:0007005 |
35 |
0.241
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
44 |
0.227
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.227
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.213
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.205
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.201
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.197
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.193
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.187
|
Fly |
|
|
cation transport
|
GO:0006812 |
382 |
0.183
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.170
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.169
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.164
|
Rat |
|
|
gtp catabolic process
|
GO:0006184 |
71 |
0.163
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
10 |
0.162
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.159
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
5 |
0.157
|
|
|
|
organelle localization
|
GO:0051640 |
55 |
0.155
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.154
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.154
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.154
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.150
|
|
|
|
mast cell activation
|
GO:0045576 |
15 |
0.149
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.149
|
Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.148
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.143
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.141
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.140
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.138
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.138
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.136
|
|
|
|
dephosphorylation
|
GO:0016311 |
98 |
0.136
|
|
|
|
mast cell degranulation
|
GO:0043303 |
10 |
0.135
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.134
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.132
|
Fly |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.132
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.131
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.130
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.129
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.129
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.128
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.123
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.123
|
|
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.122
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.121
|
Human Fly |
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.118
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.117
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.116
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
2 |
0.115
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.115
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.115
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.113
|
Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.109
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.106
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.106
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.105
|
Rat |
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.105
|
Human Fly |
|
|
programmed cell death
|
GO:0012501 |
392 |
0.104
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.103
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.103
|
Human Fly |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.102
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.100
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.100
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.099
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.098
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.097
|
|
|
|
hormone secretion
|
GO:0046879 |
115 |
0.097
|
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.097
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.096
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.095
|
Fly |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.093
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.092
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.091
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.091
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
16 |
0.089
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.089
|
Fly |
|
|
reproduction
|
GO:0000003 |
245 |
0.089
|
Fly |
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.088
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
81 |
0.088
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.088
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.088
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.088
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.088
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.087
|
Rat |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.087
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.085
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.084
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.084
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.083
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.083
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.083
|
Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.082
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.081
|
|
|
|
response to insulin
|
GO:0032868 |
133 |
0.080
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.079
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.079
|
Fly |
|
|
embryonic pattern specification
|
GO:0009880 |
1 |
0.078
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.077
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.077
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.077
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.076
|
Fly |
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.076
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.076
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.076
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.075
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.075
|
Fly |
|
|
cell activation
|
GO:0001775 |
97 |
0.075
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.074
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.074
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.073
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.072
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
78 |
0.072
|
Fly |
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.072
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.071
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.071
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.071
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.071
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.071
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.067
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
59 |
0.067
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
12 |
0.067
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
65 |
0.066
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.066
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.065
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.065
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.065
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.064
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
12 |
0.064
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.064
|
Fly |
|
|
exocytosis
|
GO:0006887 |
60 |
0.063
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.062
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.061
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.061
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.060
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
83 |
0.060
|
Human |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.060
|
Rat |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.060
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.059
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.059
|
|
|
|
protein sumoylation
|
GO:0016925 |
4 |
0.059
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.058
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.058
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.057
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.056
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.056
|
Human Fly |
|
|
histamine secretion
|
GO:0001821 |
8 |
0.056
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.056
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.055
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.055
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
16 |
0.053
|
|
|
|
axis specification
|
GO:0009798 |
4 |
0.053
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
13 |
0.052
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.051
|
Fly |
|
|
regulated secretory pathway
|
GO:0045055 |
17 |
0.051
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.051
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.050
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.050
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.049
|
|
|
|
inflammatory response
|
GO:0006954 |
150 |
0.049
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.049
|
|
|
|
immune effector process
|
GO:0002252 |
53 |
0.049
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.048
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.048
|
Human Fly |
|
|
protein prenylation
|
GO:0018342 |
4 |
0.048
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
48 |
0.048
|
Rat |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.047
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.047
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.046
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.046
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.045
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.044
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.044
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.044
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
28 |
0.044
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.044
|
Fly |
|
|
brain development
|
GO:0007420 |
247 |
0.044
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.044
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.043
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.043
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.042
|
Human Fly |
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.042
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.042
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
302 |
0.042
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.042
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.042
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.041
|
Rat |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.041
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.040
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.040
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.040
|
|
|
|
cell cycle process
|
GO:0022402 |
57 |
0.040
|
Fly |
|
|
smad protein complex assembly
|
GO:0007183 |
1 |
0.040
|
|
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.039
|
|
|
|
mesoderm development
|
GO:0007498 |
2 |
0.039
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.039
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
31 |
0.039
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.039
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.038
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.038
|
Fly |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
2 |
0.037
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
37 |
0.037
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
1 |
0.037
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.037
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.037
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.037
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.037
|
|
|
|
nuclear transport
|
GO:0051169 |
49 |
0.036
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
4 |
0.036
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.036
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.036
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
3 |
0.035
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.035
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.035
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
33 |
0.034
|
|
|
|
protein import
|
GO:0017038 |
37 |
0.034
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.034
|
Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.034
|
|
|
|
cellular response to starvation
|
GO:0009267 |
27 |
0.034
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.034
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.034
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.033
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.033
|
|
|
|
embryonic axis specification
|
GO:0000578 |
1 |
0.033
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
88 |
0.033
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.033
|
Human Fly |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.033
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
48 |
0.033
|
|
|
|
dendrite development
|
GO:0016358 |
72 |
0.033
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.033
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.032
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
84 |
0.032
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
77 |
0.032
|
Human Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.031
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.031
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.031
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.031
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.031
|
Human Fly |
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.031
|
Fly |
|
|
localization of cell
|
GO:0051674 |
202 |
0.031
|
|
|
|
cardiac chamber development
|
GO:0003205 |
1 |
0.030
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.030
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.030
|
Rat |
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.030
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
16 |
0.030
|
|
|
|
chromosome segregation
|
GO:0007059 |
2 |
0.030
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
110 |
0.029
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.029
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.029
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.029
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.029
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.029
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.029
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
2 |
0.029
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
35 |
0.029
|
Fly |
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.029
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.028
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.028
|
|
|
|
centrosome organization
|
GO:0051297 |
1 |
0.028
|
Fly |
|
|
protein targeting to mitochondrion
|
GO:0006626 |
7 |
0.028
|
|
|
|
melanosome localization
|
GO:0032400 |
1 |
0.028
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.028
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.028
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.028
|
Fly |
|
|
growth
|
GO:0040007 |
165 |
0.028
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.028
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
95 |
0.028
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
56 |
0.028
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.028
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.027
|
|
|
|
endosome to lysosome transport
|
GO:0008333 |
6 |
0.027
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.027
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
72 |
0.027
|
Human |
|
|
aging
|
GO:0007568 |
241 |
0.027
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
86 |
0.027
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.026
|
Human Fly |
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.026
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.026
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.026
|
|
|
|
cell fate determination
|
GO:0001709 |
2 |
0.026
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.025
|
|
|
|
autophagic cell death
|
GO:0048102 |
4 |
0.025
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
78 |
0.025
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.025
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.025
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.024
|
|
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.024
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.024
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
32 |
0.024
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
87 |
0.023
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.023
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.023
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.023
|
|
|
|
cofactor biosynthetic process
|
GO:0051188 |
28 |
0.023
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
38 |
0.023
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.023
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.022
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.022
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.022
|
Fly |
|
|
immune response to tumor cell
|
GO:0002418 |
3 |
0.022
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
3 |
0.022
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.022
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
58 |
0.022
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
7 |
0.022
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.021
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.021
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.021
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.021
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
118 |
0.021
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.021
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.021
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.020
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.020
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
45 |
0.020
|
Rat |
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.020
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.020
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.020
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
66 |
0.020
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.020
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
72 |
0.020
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.020
|
Human |
|
|
myeloid leukocyte activation
|
GO:0002274 |
36 |
0.020
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.020
|
Human Fly |
|
|
lysosomal transport
|
GO:0007041 |
8 |
0.020
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.019
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.019
|
Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.019
|
|
|
|
male gamete generation
|
GO:0048232 |
99 |
0.019
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
49 |
0.019
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.019
|
|
|
|
chlorinated hydrocarbon metabolic process
|
GO:0042196 |
4 |
0.019
|
|
|
|
protein refolding
|
GO:0042026 |
3 |
0.019
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.019
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
71 |
0.019
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
55 |
0.019
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
23 |
0.019
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
41 |
0.019
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
4 |
0.019
|
|
|
|
p38mapk cascade
|
GO:0038066 |
1 |
0.019
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.019
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
122 |
0.018
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.018
|
Human Fly |
|
|
single organism nuclear import
|
GO:1902593 |
35 |
0.018
|
|
|
|
nuclear import
|
GO:0051170 |
35 |
0.018
|
|
|
|
autophagy
|
GO:0006914 |
19 |
0.018
|
Fly |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.018
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.018
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.018
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
35 |
0.018
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.018
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.018
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.017
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.017
|
|
|
|
spermatogenesis
|
GO:0007283 |
99 |
0.017
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
60 |
0.017
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.017
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.017
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.017
|
Fly |
|
|
positive regulation of phosphoprotein phosphatase activity
|
GO:0032516 |
3 |
0.017
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.017
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.017
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.017
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.017
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
28 |
0.016
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
57 |
0.016
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
4 |
0.016
|
|
|
|
anterograde axon cargo transport
|
GO:0008089 |
1 |
0.016
|
|
|
|
halogenated hydrocarbon metabolic process
|
GO:0042197 |
4 |
0.016
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
46 |
0.016
|
|
|
|
acrosome assembly
|
GO:0001675 |
3 |
0.016
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
84 |
0.016
|
|
|
|
stem cell maintenance
|
GO:0019827 |
6 |
0.016
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.016
|
|
|
|
rna localization
|
GO:0006403 |
4 |
0.016
|
|
|
|
regulation of p38mapk cascade
|
GO:1900744 |
1 |
0.016
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.016
|
Fly |
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.016
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.016
|
|
|
|
histamine transport
|
GO:0051608 |
9 |
0.015
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
65 |
0.015
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.015
|
|
|
|
head development
|
GO:0060322 |
247 |
0.015
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
19 |
0.015
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.015
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.015
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
1 |
0.015
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.015
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
2 |
0.015
|
Fly |
|
|
immune response
|
GO:0006955 |
104 |
0.015
|
|
|
|
cell junction maintenance
|
GO:0034331 |
1 |
0.015
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.015
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.015
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
57 |
0.014
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.014
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.014
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.014
|
Human |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
3 |
0.014
|
|
|
|
organelle fission
|
GO:0048285 |
25 |
0.014
|
Fly |
|
|
regulation of system process
|
GO:0044057 |
208 |
0.014
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
23 |
0.014
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
73 |
0.014
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
24 |
0.014
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
2 |
0.014
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.014
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.014
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
10 |
0.014
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
37 |
0.014
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.014
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.014
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
70 |
0.014
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
3 |
0.014
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
126 |
0.014
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.014
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
2 |
0.014
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.014
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.014
|
|
|
|
heart development
|
GO:0007507 |
72 |
0.014
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
2 |
0.014
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
23 |
0.014
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
17 |
0.013
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.013
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
7 |
0.013
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.013
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.013
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.013
|
|
|
|
protein import into nucleus
|
GO:0006606 |
35 |
0.013
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.013
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
65 |
0.012
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.012
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.012
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
25 |
0.012
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.012
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
58 |
0.012
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
31 |
0.012
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.012
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.012
|
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
22 |
0.012
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
103 |
0.012
|
|
|
|
eye development
|
GO:0001654 |
50 |
0.012
|
Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.012
|
|
|
|
single fertilization
|
GO:0007338 |
3 |
0.012
|
|
|
|
reproductive system development
|
GO:0061458 |
128 |
0.012
|
|
|
|
somatic stem cell division
|
GO:0048103 |
2 |
0.012
|
Fly |
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
2 |
0.012
|
|
|
|
maintenance of location
|
GO:0051235 |
17 |
0.012
|
|
|
|
axon cargo transport
|
GO:0008088 |
1 |
0.012
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
3 |
0.012
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
66 |
0.012
|
|
|
|
response to axon injury
|
GO:0048678 |
59 |
0.012
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.012
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.012
|
|
|
|
protein localization to membrane
|
GO:0072657 |
36 |
0.012
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
34 |
0.012
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.012
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.012
|
|
|
|
regulation of axon extension
|
GO:0030516 |
24 |
0.012
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.012
|
|
|
|
response to antibiotic
|
GO:0046677 |
39 |
0.011
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.011
|
|
|
|
response to calcium ion
|
GO:0051592 |
59 |
0.011
|
|
|
|
organelle assembly
|
GO:0070925 |
22 |
0.011
|
Fly |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.011
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
55 |
0.011
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.011
|
Human |
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.011
|
|
