Rattus norvegicus

0 known processes

Llgl2

lethal giant larvae homolog 2 (Drosophila)

(Aliases: RGD1560307)

Llgl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.102
response to peptide GO:1901652 292 0.090
oxoacid metabolic process GO:0043436 290 0.077
carboxylic acid metabolic process GO:0019752 289 0.074
macromolecular complex assembly GO:0065003 273 0.071
single organism biosynthetic process GO:0044711 342 0.069
carbohydrate derivative metabolic process GO:1901135 346 0.066
Rat
regulation of rna biosynthetic process GO:2001141 381 0.060
cellular response to oxygen containing compound GO:1901701 386 0.059
catabolic process GO:0009056 351 0.055
Rat
rna biosynthetic process GO:0032774 380 0.053
macromolecular complex subunit organization GO:0043933 339 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
Rat
response to extracellular stimulus GO:0009991 380 0.052
regulation of rna metabolic process GO:0051252 391 0.051
cellular component biogenesis GO:0044085 368 0.050
cellular component assembly GO:0022607 360 0.050
rna metabolic process GO:0016070 406 0.049
response to nutrient levels GO:0031667 370 0.048
regulation of nucleic acid templated transcription GO:1903506 380 0.047
cellular amino acid metabolic process GO:0006520 107 0.047
regulation of cellular ketone metabolic process GO:0010565 27 0.047
cellular ketone metabolic process GO:0042180 51 0.045
regulation of molecular function GO:0065009 398 0.045
Rat
transcription dna templated GO:0006351 377 0.045
response to acid chemical GO:0001101 222 0.045
apoptotic process GO:0006915 381 0.044
regulation of transcription dna templated GO:0006355 374 0.043
neuron development GO:0048666 286 0.043
Rat
secretion by cell GO:0032940 248 0.042
response to biotic stimulus GO:0009607 226 0.042
protein complex biogenesis GO:0070271 263 0.042
regulation of programmed cell death GO:0043067 341 0.041
regulation of catalytic activity GO:0050790 304 0.041
Rat
intracellular signal transduction GO:0035556 314 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
Rat
regulation of intracellular signal transduction GO:1902531 218 0.040
Rat
central nervous system development GO:0007417 311 0.039
homeostatic process GO:0042592 331 0.039
negative regulation of multicellular organismal process GO:0051241 203 0.038
protein phosphorylation GO:0006468 345 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
Rat
response to insulin GO:0032868 133 0.037
protein complex assembly GO:0006461 263 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
secretion GO:0046903 307 0.036
nucleic acid templated transcription GO:0097659 379 0.036
regulation of protein modification process GO:0031399 194 0.036
response to wounding GO:0009611 254 0.036
positive regulation of molecular function GO:0044093 230 0.035
Rat
protein oligomerization GO:0051259 191 0.035
response to inorganic substance GO:0010035 377 0.035
organic substance catabolic process GO:1901575 316 0.035
Rat
lipid metabolic process GO:0006629 283 0.035
regulation of apoptotic process GO:0042981 335 0.034
cellular catabolic process GO:0044248 295 0.034
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
regulation of nervous system development GO:0051960 264 0.034
response to peptide hormone GO:0043434 278 0.033
programmed cell death GO:0012501 392 0.033
transmembrane transport GO:0055085 412 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
Rat
single organism catabolic process GO:0044712 283 0.032
Rat
neuron projection development GO:0031175 273 0.032
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.032
cellular response to alcohol GO:0097306 87 0.032
positive regulation of transcription dna templated GO:0045893 197 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
response to other organism GO:0051707 220 0.031
positive regulation of gene expression GO:0010628 244 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
Rat
regulation of cellular component organization GO:0051128 368 0.030
organophosphate metabolic process GO:0019637 370 0.030
Rat
cellular response to hormone stimulus GO:0032870 247 0.030
response to metal ion GO:0010038 253 0.029
anion transport GO:0006820 178 0.029
regulation of protein metabolic process GO:0051246 289 0.029
cellular response to lipid GO:0071396 201 0.029
response to ketone GO:1901654 182 0.029
regulation of multicellular organismal development GO:2000026 376 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
Rat
protein complex subunit organization GO:0071822 302 0.028
aging GO:0007568 241 0.028
regulation of cellular catabolic process GO:0031329 101 0.028
Rat
regulation of protein phosphorylation GO:0001932 183 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
negative regulation of metabolic process GO:0009892 331 0.027
regulation of neuron projection development GO:0010975 161 0.027
regulation of neurogenesis GO:0050767 247 0.027
regulation of cellular localization GO:0060341 263 0.027
response to nutrient GO:0007584 248 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
positive regulation of signaling GO:0023056 270 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
amine metabolic process GO:0009308 38 0.027
positive regulation of cell communication GO:0010647 271 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
chemical homeostasis GO:0048878 292 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
Rat
synaptic transmission GO:0007268 235 0.025
macromolecule localization GO:0033036 252 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
response to corticosteroid GO:0031960 235 0.025
regulation of system process GO:0044057 208 0.025
regulation of secretion by cell GO:1903530 208 0.024
cell cell signaling GO:0007267 335 0.024
neuron differentiation GO:0030182 368 0.024
Rat
response to external biotic stimulus GO:0043207 221 0.024
positive regulation of nervous system development GO:0051962 178 0.024
cellular amine metabolic process GO:0044106 38 0.024
oxidation reduction process GO:0055114 304 0.024
response to decreased oxygen levels GO:0036293 237 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regulation of cell projection organization GO:0031344 175 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
blood circulation GO:0008015 183 0.023
response to vitamin GO:0033273 131 0.023
cell projection organization GO:0030030 302 0.023
Rat
response to bacterium GO:0009617 200 0.023
negative regulation of gene expression GO:0010629 199 0.023
regulation of cell development GO:0060284 263 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
cellular component movement GO:0006928 248 0.023
regulation of phosphorylation GO:0042325 248 0.022
eye morphogenesis GO:0048592 4 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
regulation of secretion GO:0051046 224 0.022
cellular response to abiotic stimulus GO:0071214 85 0.022
nitrogen compound transport GO:0071705 229 0.022
purine containing compound metabolic process GO:0072521 253 0.022
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
negative regulation of cell proliferation GO:0008285 119 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
carbohydrate derivative biosynthetic process GO:1901137 124 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
regulation of signal transduction GO:0009966 318 0.021
Rat
positive regulation of neurogenesis GO:0050769 165 0.021
signal transduction by phosphorylation GO:0023014 144 0.021
localization of cell GO:0051674 202 0.021
positive regulation of protein modification process GO:0031401 142 0.021
response to glucocorticoid GO:0051384 223 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
brain development GO:0007420 247 0.020
response to growth factor GO:0070848 189 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
regulation of hormone levels GO:0010817 187 0.020
organic anion transport GO:0015711 132 0.020
regulation of blood circulation GO:1903522 110 0.020
response to lipopolysaccharide GO:0032496 191 0.020
nucleoside metabolic process GO:0009116 179 0.020
Rat
regulation of catabolic process GO:0009894 113 0.020
Rat
multi organism reproductive process GO:0044703 262 0.020
regulation of cell differentiation GO:0045595 320 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
Rat
nucleotide metabolic process GO:0009117 279 0.020
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
metal ion transport GO:0030001 289 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
heterocycle catabolic process GO:0046700 167 0.020
Rat
cation transport GO:0006812 382 0.020
lipid biosynthetic process GO:0008610 128 0.020
protein localization GO:0008104 191 0.020
regulation of neuron differentiation GO:0045664 208 0.020
organelle organization GO:0006996 266 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
Rat
organic acid transport GO:0015849 116 0.019
cellular response to external stimulus GO:0071496 118 0.019
regulation of lipid metabolic process GO:0019216 68 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
Rat
protein transport GO:0015031 132 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
locomotion GO:0040011 237 0.019
tissue development GO:0009888 252 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
Rat
regulation of locomotion GO:0040012 148 0.019
regulation of cell proliferation GO:0042127 359 0.019
positive regulation of cell development GO:0010720 176 0.019
positive regulation of transport GO:0051050 245 0.018
negative regulation of molecular function GO:0044092 133 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
positive regulation of signal transduction GO:0009967 175 0.018
amino acid transport GO:0006865 70 0.018
cellular response to stress GO:0033554 269 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
regulation of protein kinase activity GO:0045859 105 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
Rat
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
carboxylic acid transport GO:0046942 115 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
Rat
response to hypoxia GO:0001666 231 0.017
vesicle mediated transport GO:0016192 181 0.017
Rat
response to oxygen levels GO:0070482 265 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
ion homeostasis GO:0050801 212 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.017
carbohydrate metabolic process GO:0005975 130 0.017
single organism behavior GO:0044708 130 0.017
mapk cascade GO:0000165 140 0.017
ras protein signal transduction GO:0007265 29 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
aromatic compound catabolic process GO:0019439 168 0.017
Rat
regulation of cellular component movement GO:0051270 150 0.017
multicellular organismal signaling GO:0035637 44 0.017
response to alkaloid GO:0043279 132 0.016
signal release GO:0023061 145 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
Rat
cation transmembrane transport GO:0098655 263 0.016
cell part morphogenesis GO:0032990 123 0.016
Rat
gastrulation GO:0007369 2 0.016
regulation of kinase activity GO:0043549 117 0.016
amide transport GO:0042886 105 0.016
response to toxic substance GO:0009636 133 0.016
reproductive structure development GO:0048608 128 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
organophosphate catabolic process GO:0046434 148 0.016
Rat
regulation of mapk cascade GO:0043408 116 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
multicellular organism growth GO:0035264 1 0.016
cation homeostasis GO:0055080 195 0.016
negative regulation of cell communication GO:0010648 158 0.016
cellular protein localization GO:0034613 122 0.016
ion transmembrane transport GO:0034220 365 0.016
transmission of nerve impulse GO:0019226 42 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
dna metabolic process GO:0006259 96 0.015
cellular homeostasis GO:0019725 252 0.015
hepaticobiliary system development GO:0061008 90 0.015
response to cytokine GO:0034097 215 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
Rat
gland development GO:0048732 155 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
regeneration GO:0031099 163 0.015
response to oxidative stress GO:0006979 186 0.015
response to radiation GO:0009314 137 0.015
defense response GO:0006952 194 0.015
regulation of transferase activity GO:0051338 123 0.015
negative regulation of cell death GO:0060548 229 0.015
adult locomotory behavior GO:0008344 4 0.015
response to glucose GO:0009749 136 0.015
response to estrogen GO:0043627 232 0.015
response to ethanol GO:0045471 162 0.015
regulation of cell migration GO:0030334 128 0.014
cellular chemical homeostasis GO:0055082 247 0.014
peptide transport GO:0015833 97 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
Rat
metal ion homeostasis GO:0055065 186 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
regulation of anatomical structure size GO:0090066 135 0.014
mesoderm development GO:0007498 2 0.014
intracellular transport GO:0046907 185 0.014
Rat
negative regulation of protein metabolic process GO:0051248 114 0.014
cell motility GO:0048870 202 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
Rat
ribonucleotide catabolic process GO:0009261 136 0.014
Rat
organic cyclic compound catabolic process GO:1901361 175 0.014
Rat
monosaccharide metabolic process GO:0005996 61 0.014
regulation of blood vessel size GO:0050880 89 0.014
regulation of tube size GO:0035150 89 0.014
positive regulation of kinase activity GO:0033674 77 0.014
axis specification GO:0009798 4 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
regulation of response to stress GO:0080134 126 0.014
development of primary sexual characteristics GO:0045137 107 0.014
multicellular organism reproduction GO:0032504 233 0.014
multi multicellular organism process GO:0044706 138 0.014
rhythmic process GO:0048511 156 0.014
cell migration GO:0016477 197 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
regulation of growth GO:0040008 105 0.014
regulation of protein localization GO:0032880 81 0.013
wound healing GO:0042060 122 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
Rat
steroid biosynthetic process GO:0006694 48 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
circulatory system process GO:0003013 183 0.013
activation of protein kinase activity GO:0032147 47 0.013
single organism reproductive process GO:0044702 297 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
Rat
cell morphogenesis GO:0000902 142 0.013
Rat
regulation of hydrolase activity GO:0051336 143 0.013
Rat
response to transition metal nanoparticle GO:1990267 122 0.013
cellular response to acid chemical GO:0071229 75 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
Rat
regulation of blood pressure GO:0008217 83 0.013
regulation of neuron death GO:1901214 115 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of cellular response to stress GO:0080135 49 0.013
heart morphogenesis GO:0003007 3 0.013
chromosome segregation GO:0007059 2 0.013
hexose metabolic process GO:0019318 58 0.013
response to starvation GO:0042594 59 0.013
neurological system process GO:0050877 219 0.013
positive regulation of rna metabolic process GO:0051254 203 0.012
response to fatty acid GO:0070542 65 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cellular ion homeostasis GO:0006873 184 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of locomotion GO:0040017 102 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of cell motility GO:2000145 131 0.012
negative regulation of signaling GO:0023057 157 0.012
lipid storage GO:0019915 1 0.012
positive regulation of developmental process GO:0051094 283 0.012
regulation of hormone secretion GO:0046883 106 0.012
embryonic pattern specification GO:0009880 1 0.012
regulation of body fluid levels GO:0050878 90 0.012
positive regulation of cell death GO:0010942 184 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
negative regulation of transport GO:0051051 136 0.012
response to estradiol GO:0032355 164 0.012
developmental process involved in reproduction GO:0003006 159 0.012
forebrain development GO:0030900 98 0.012
behavior GO:0007610 205 0.012
female pregnancy GO:0007565 122 0.012
cytoplasmic transport GO:0016482 115 0.012
Rat
establishment of protein localization GO:0045184 141 0.012
anterior posterior pattern specification GO:0009952 1 0.012
lipid localization GO:0010876 62 0.012
cell type specific apoptotic process GO:0097285 134 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
response to activity GO:0014823 73 0.011
positive regulation of secretion GO:0051047 140 0.011
gamete generation GO:0007276 124 0.011
naphthalene containing compound metabolic process GO:0090420 2 0.011
regulation of metal ion transport GO:0010959 118 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
nucleotide catabolic process GO:0009166 139 0.011
Rat
positive regulation of catabolic process GO:0009896 78 0.011
Rat
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
positive regulation of cell motility GO:2000147 97 0.011
negative regulation of viral process GO:0048525 4 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
camera type eye morphogenesis GO:0048593 2 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
Rat
protein heterooligomerization GO:0051291 89 0.011
cellular component morphogenesis GO:0032989 155 0.011
Rat
response to monosaccharide GO:0034284 159 0.011
dephosphorylation GO:0016311 98 0.011
rho protein signal transduction GO:0007266 11 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of response to external stimulus GO:0032101 106 0.011
action potential GO:0001508 54 0.011
growth GO:0040007 165 0.011
response to retinoic acid GO:0032526 63 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
head development GO:0060322 247 0.011
formation of primary germ layer GO:0001704 1 0.011
muscle cell proliferation GO:0033002 84 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
liver development GO:0001889 90 0.011
cellular response to peptide GO:1901653 133 0.011
regulation of dna metabolic process GO:0051052 60 0.011
sexual reproduction GO:0019953 148 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
peptide hormone secretion GO:0030072 84 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.010
Rat
reactive nitrogen species metabolic process GO:2001057 1 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
Rat
cellular response to insulin stimulus GO:0032869 81 0.010
hormone metabolic process GO:0042445 69 0.010
response to hexose GO:0009746 144 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
regulation of cell growth GO:0001558 85 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
neuronal action potential GO:0019228 35 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
Rat
intracellular protein transport GO:0006886 79 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
Rat
cellular cation homeostasis GO:0030003 180 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
single organism intracellular transport GO:1902582 166 0.010
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.010
Rat
cellular lipid metabolic process GO:0044255 208 0.010
peptide secretion GO:0002790 86 0.010
purine containing compound catabolic process GO:0072523 138 0.010
Rat
hormone secretion GO:0046879 115 0.010
peptidyl amino acid modification GO:0018193 126 0.010

Llgl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
sensory system disease DOID:0050155 0 0.035
disease of metabolism DOID:0014667 0 0.025
eye and adnexa disease DOID:1492 0 0.025
eye disease DOID:5614 0 0.025
retinal disease DOID:5679 0 0.021
musculoskeletal system disease DOID:17 0 0.020
inherited metabolic disorder DOID:655 0 0.013
retinal degeneration DOID:8466 0 0.011
connective tissue disease DOID:65 0 0.011
central nervous system disease DOID:331 0 0.011
bone disease DOID:0080001 0 0.010