Rattus norvegicus

0 known processes

Gpx5

glutathione peroxidase 5

Gpx5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.145
regulation of phosphate metabolic process GO:0019220 349 0.110
programmed cell death GO:0012501 392 0.096
regulation of cell proliferation GO:0042127 359 0.088
cellular catabolic process GO:0044248 295 0.087
apoptotic process GO:0006915 381 0.080
positive regulation of cell communication GO:0010647 271 0.076
positive regulation of biosynthetic process GO:0009891 319 0.072
regulation of transcription dna templated GO:0006355 374 0.071
response to molecule of bacterial origin GO:0002237 194 0.071
oxoacid metabolic process GO:0043436 290 0.070
negative regulation of metabolic process GO:0009892 331 0.067
rna metabolic process GO:0016070 406 0.067
single organism biosynthetic process GO:0044711 342 0.067
response to peptide hormone GO:0043434 278 0.062
reproductive process GO:0022414 372 0.061
nucleic acid templated transcription GO:0097659 379 0.059
cellular component biogenesis GO:0044085 368 0.058
negative regulation of macromolecule metabolic process GO:0010605 260 0.056
organic acid metabolic process GO:0006082 292 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
intracellular signal transduction GO:0035556 314 0.054
organophosphate metabolic process GO:0019637 370 0.054
cellular response to corticosteroid stimulus GO:0071384 69 0.054
negative regulation of cellular metabolic process GO:0031324 281 0.054
regulation of neuron projection development GO:0010975 161 0.052
anterior posterior pattern specification GO:0009952 1 0.052
response to mechanical stimulus GO:0009612 134 0.051
neuron development GO:0048666 286 0.051
positive regulation of cell differentiation GO:0045597 217 0.050
negative regulation of gene expression GO:0010629 199 0.050
regulation of protein metabolic process GO:0051246 289 0.050
regulation of apoptotic process GO:0042981 335 0.050
rna biosynthetic process GO:0032774 380 0.049
multicellular organism reproduction GO:0032504 233 0.048
cellular response to oxygen containing compound GO:1901701 386 0.048
organelle organization GO:0006996 266 0.047
single organism catabolic process GO:0044712 283 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.045
regulation of programmed cell death GO:0043067 341 0.045
positive regulation of transport GO:0051050 245 0.045
response to external biotic stimulus GO:0043207 221 0.045
locomotion GO:0040011 237 0.044
regulation of multicellular organismal development GO:2000026 376 0.044
cellular response to hormone stimulus GO:0032870 247 0.042
neuron differentiation GO:0030182 368 0.041
regulation of nervous system development GO:0051960 264 0.041
transcription dna templated GO:0006351 377 0.041
positive regulation of cell motility GO:2000147 97 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.041
neuron projection development GO:0031175 273 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.040
regulation of cell differentiation GO:0045595 320 0.039
response to wounding GO:0009611 254 0.039
regulation of phosphorus metabolic process GO:0051174 349 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
regulation of molecular function GO:0065009 398 0.038
regulation of cellular component organization GO:0051128 368 0.038
positive regulation of developmental process GO:0051094 283 0.037
response to growth factor GO:0070848 189 0.036
single organism organelle organization GO:1902589 180 0.034
positive regulation of signaling GO:0023056 270 0.034
heterocycle catabolic process GO:0046700 167 0.034
organic substance catabolic process GO:1901575 316 0.034
response to nutrient GO:0007584 248 0.034
regulation of rna metabolic process GO:0051252 391 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.034
response to other organism GO:0051707 220 0.033
cellular component movement GO:0006928 248 0.033
cell projection organization GO:0030030 302 0.033
cellular response to endogenous stimulus GO:0071495 377 0.033
sexual reproduction GO:0019953 148 0.033
catabolic process GO:0009056 351 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
protein phosphorylation GO:0006468 345 0.032
negative regulation of biosynthetic process GO:0009890 168 0.032
regulation of signal transduction GO:0009966 318 0.032
regulation of cell projection organization GO:0031344 175 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
response to nutrient levels GO:0031667 370 0.032
central nervous system development GO:0007417 311 0.032
carboxylic acid metabolic process GO:0019752 289 0.032
organic hydroxy compound metabolic process GO:1901615 115 0.031
positive regulation of transcription dna templated GO:0045893 197 0.031
purine containing compound metabolic process GO:0072521 253 0.031
positive regulation of cell proliferation GO:0008284 249 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
defense response GO:0006952 194 0.030
positive regulation of nervous system development GO:0051962 178 0.030
positive regulation of gene expression GO:0010628 244 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
response to cytokine GO:0034097 215 0.030
regulation of neurogenesis GO:0050767 247 0.030
purine nucleotide metabolic process GO:0006163 229 0.030
embryonic skeletal system development GO:0048706 3 0.029
reproduction GO:0000003 245 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
regulation of response to stress GO:0080134 126 0.029
response to extracellular stimulus GO:0009991 380 0.029
nucleotide catabolic process GO:0009166 139 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
cellular response to steroid hormone stimulus GO:0071383 93 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
positive regulation of locomotion GO:0040017 102 0.027
cellular component assembly GO:0022607 360 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
cellular response to peptide hormone stimulus GO:0071375 120 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
regeneration GO:0031099 163 0.027
response to peptide GO:1901652 292 0.027
response to biotic stimulus GO:0009607 226 0.027
inflammatory response GO:0006954 150 0.027
response to inorganic substance GO:0010035 377 0.026
response to alkaloid GO:0043279 132 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
regulation of cell development GO:0060284 263 0.026
mapk cascade GO:0000165 140 0.026
single organism reproductive process GO:0044702 297 0.026
response to lipopolysaccharide GO:0032496 191 0.026
regulation of neuron differentiation GO:0045664 208 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
positive regulation of molecular function GO:0044093 230 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
regulation of cellular localization GO:0060341 263 0.025
immune system process GO:0002376 204 0.025
nephric duct development GO:0072176 1 0.025
negative regulation of cell death GO:0060548 229 0.025
cell cell signaling GO:0007267 335 0.024
response to acid chemical GO:0001101 222 0.024
multi organism reproductive process GO:0044703 262 0.024
hormone transport GO:0009914 121 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
positive regulation of cellular component movement GO:0051272 102 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
regulation of catalytic activity GO:0050790 304 0.023
cellular response to lipid GO:0071396 201 0.023
nucleoside metabolic process GO:0009116 179 0.023
nucleotide metabolic process GO:0009117 279 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
tissue development GO:0009888 252 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
gamete generation GO:0007276 124 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
homeostatic process GO:0042592 331 0.022
negative regulation of cell proliferation GO:0008285 119 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
cofactor metabolic process GO:0051186 95 0.022
amine metabolic process GO:0009308 38 0.022
nitrogen compound transport GO:0071705 229 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
regulation of vesicle mediated transport GO:0060627 81 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
regulation of locomotion GO:0040012 148 0.021
cell morphogenesis GO:0000902 142 0.021
cytoskeleton organization GO:0007010 111 0.021
cellular response to glucocorticoid stimulus GO:0071385 68 0.021
embryonic pattern specification GO:0009880 1 0.021
coenzyme metabolic process GO:0006732 86 0.021
axis specification GO:0009798 4 0.021
cellular response to peptide GO:1901653 133 0.021
protein complex biogenesis GO:0070271 263 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
organophosphate catabolic process GO:0046434 148 0.021
ras protein signal transduction GO:0007265 29 0.021
response to insulin GO:0032868 133 0.020
head development GO:0060322 247 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
cellular amine metabolic process GO:0044106 38 0.020
aromatic compound catabolic process GO:0019439 168 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
intracellular transport GO:0046907 185 0.020
oxidation reduction process GO:0055114 304 0.020
proteolysis GO:0006508 175 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
positive regulation of cell development GO:0010720 176 0.020
cellular component morphogenesis GO:0032989 155 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
positive regulation of programmed cell death GO:0043068 157 0.019
leukocyte migration GO:0050900 38 0.019
response to oxidative stress GO:0006979 186 0.019
brain development GO:0007420 247 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
positive regulation of signal transduction GO:0009967 175 0.019
ribose phosphate biosynthetic process GO:0046390 87 0.019
response to carbohydrate GO:0009743 183 0.019
purine containing compound biosynthetic process GO:0072522 85 0.018
regulation of mapk cascade GO:0043408 116 0.018
neurological system process GO:0050877 219 0.018
male gamete generation GO:0048232 99 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
regulation of anatomical structure size GO:0090066 135 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
response to hypoxia GO:0001666 231 0.018
localization of cell GO:0051674 202 0.018
spermatogenesis GO:0007283 99 0.017
cation transport GO:0006812 382 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
response to estrogen GO:0043627 232 0.017
cell part morphogenesis GO:0032990 123 0.017
positive regulation of secretion GO:0051047 140 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
embryonic skeletal system morphogenesis GO:0048704 3 0.017
cell type specific apoptotic process GO:0097285 134 0.017
developmental growth GO:0048589 100 0.017
regulation of phosphorylation GO:0042325 248 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
positive regulation of cell death GO:0010942 184 0.017
response to estradiol GO:0032355 164 0.017
cell motility GO:0048870 202 0.017
hormone secretion GO:0046879 115 0.017
regulation of secretion by cell GO:1903530 208 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
secretion by cell GO:0032940 248 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
motor neuron axon guidance GO:0008045 1 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
dendrite development GO:0016358 72 0.016
ephrin receptor signaling pathway GO:0048013 3 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to antibiotic GO:0046677 39 0.016
cellular chemical homeostasis GO:0055082 247 0.016
negative regulation of developmental process GO:0051093 125 0.016
cellular ketone metabolic process GO:0042180 51 0.016
neuron projection morphogenesis GO:0048812 122 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
response to bacterium GO:0009617 200 0.016
axon development GO:0061564 96 0.015
response to hexose GO:0009746 144 0.015
axonogenesis GO:0007409 71 0.015
purine containing compound catabolic process GO:0072523 138 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
response to decreased oxygen levels GO:0036293 237 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
regulation of cell migration GO:0030334 128 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
response to radiation GO:0009314 137 0.015
regulation of cell motility GO:2000145 131 0.015
response to axon injury GO:0048678 59 0.014
kidney development GO:0001822 67 0.014
response to glucose GO:0009749 136 0.014
positive regulation of cell migration GO:0030335 96 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
dna metabolic process GO:0006259 96 0.014
regulation of hormone levels GO:0010817 187 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
response to glucocorticoid GO:0051384 223 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
lipid storage GO:0019915 1 0.014
embryonic axis specification GO:0000578 1 0.014
regulation of transferase activity GO:0051338 123 0.014
protein localization GO:0008104 191 0.014
regulation of response to external stimulus GO:0032101 106 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.013
maintenance of location GO:0051235 17 0.013
phasic smooth muscle contraction GO:0014821 3 0.013
cellular homeostasis GO:0019725 252 0.013
regulation of catabolic process GO:0009894 113 0.013
gliogenesis GO:0042063 93 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
gastrulation GO:0007369 2 0.013
reproductive structure development GO:0048608 128 0.013
eye morphogenesis GO:0048592 4 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
forebrain development GO:0030900 98 0.013
macromolecular complex assembly GO:0065003 273 0.013
secretion GO:0046903 307 0.013
gtp catabolic process GO:0006184 71 0.013
behavior GO:0007610 205 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of hydrolase activity GO:0051336 143 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
cardiovascular system development GO:0072358 134 0.013
synaptic transmission GO:0007268 235 0.013
neuron apoptotic process GO:0051402 88 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
protein transport GO:0015031 132 0.013
protein complex assembly GO:0006461 263 0.013
eye development GO:0001654 50 0.012
macromolecule localization GO:0033036 252 0.012
positive regulation of kinase activity GO:0033674 77 0.012
protein autophosphorylation GO:0046777 66 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
protein complex subunit organization GO:0071822 302 0.012
negative regulation of innate immune response GO:0045824 4 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
sensory perception GO:0007600 101 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
single organism cellular localization GO:1902580 102 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
actin filament based process GO:0030029 86 0.012
brain renin angiotensin system GO:0002035 3 0.012
response to ketone GO:1901654 182 0.012
response to monosaccharide GO:0034284 159 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
lipid metabolic process GO:0006629 283 0.012
cell growth GO:0016049 104 0.012
cellular response to stress GO:0033554 269 0.012
neuron death GO:0070997 127 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
regulation of immune system process GO:0002682 123 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
cytoplasmic transport GO:0016482 115 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of synaptic transmission GO:0050804 141 0.011
regulation of system process GO:0044057 208 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
oxidoreduction coenzyme metabolic process GO:0006733 31 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of ion transport GO:0043269 245 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
carboxylic acid transport GO:0046942 115 0.011
detection of visible light GO:0009584 3 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
regulation of saliva secretion GO:0046877 3 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
chemical homeostasis GO:0048878 292 0.011
exocytosis GO:0006887 60 0.011
heart development GO:0007507 72 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
response to amino acid GO:0043200 75 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
response to metal ion GO:0010038 253 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
negative regulation of proteolysis GO:0045861 41 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
positive regulation of response to external stimulus GO:0032103 51 0.011
response to vitamin GO:0033273 131 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
multi multicellular organism process GO:0044706 138 0.010
chemosensory behavior GO:0007635 2 0.010
response to electrical stimulus GO:0051602 56 0.010
regulation of protein kinase activity GO:0045859 105 0.010
regulation of protein modification process GO:0031399 194 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
cellular cation homeostasis GO:0030003 180 0.010
chromosome segregation GO:0007059 2 0.010
peptidyl amino acid modification GO:0018193 126 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
regulation of membrane potential GO:0042391 110 0.010
cell migration GO:0016477 197 0.010
negative regulation of signaling GO:0023057 157 0.010
fertilization GO:0009566 3 0.010

Gpx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
gastrointestinal system disease DOID:77 0 0.012
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
central nervous system disease DOID:331 0 0.010