Rattus norvegicus

0 known processes

Spg7

spastic paraplegia 7 homolog (human)

Spg7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 351 0.057
homeostatic process GO:0042592 331 0.044
cellular catabolic process GO:0044248 295 0.044
organic acid metabolic process GO:0006082 292 0.042
carboxylic acid metabolic process GO:0019752 289 0.035
oxoacid metabolic process GO:0043436 290 0.035
transmembrane transport GO:0055085 412 0.034
single organism biosynthetic process GO:0044711 342 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
organelle organization GO:0006996 266 0.031
ion transmembrane transport GO:0034220 365 0.030
cellular component assembly GO:0022607 360 0.029
cellular lipid metabolic process GO:0044255 208 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
protein phosphorylation GO:0006468 345 0.028
chemical homeostasis GO:0048878 292 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
programmed cell death GO:0012501 392 0.028
cation transport GO:0006812 382 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
protein complex subunit organization GO:0071822 302 0.026
organic substance catabolic process GO:1901575 316 0.026
metal ion transport GO:0030001 289 0.026
cellular component biogenesis GO:0044085 368 0.025
secretion by cell GO:0032940 248 0.025
cation transmembrane transport GO:0098655 263 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
response to peptide hormone GO:0043434 278 0.023
macromolecular complex assembly GO:0065003 273 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
single organism catabolic process GO:0044712 283 0.023
lipid metabolic process GO:0006629 283 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
positive regulation of transport GO:0051050 245 0.022
intracellular transport GO:0046907 185 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
cellular ketone metabolic process GO:0042180 51 0.021
single organism intracellular transport GO:1902582 166 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
secretion GO:0046903 307 0.020
cellular amine metabolic process GO:0044106 38 0.020
response to inorganic substance GO:0010035 377 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
neuron differentiation GO:0030182 368 0.020
reproductive process GO:0022414 372 0.019
positive regulation of developmental process GO:0051094 283 0.019
cell projection organization GO:0030030 302 0.019
amine metabolic process GO:0009308 38 0.019
regulation of apoptotic process GO:0042981 335 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
positive regulation of cell communication GO:0010647 271 0.019
organophosphate metabolic process GO:0019637 370 0.018
oxidation reduction process GO:0055114 304 0.018
cellular homeostasis GO:0019725 252 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
apoptotic process GO:0006915 381 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
small molecule biosynthetic process GO:0044283 124 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
organic acid biosynthetic process GO:0016053 83 0.018
regulation of cell proliferation GO:0042127 359 0.017
reproduction GO:0000003 245 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
response to nutrient levels GO:0031667 370 0.017
positive regulation of nervous system development GO:0051962 178 0.017
regulation of molecular function GO:0065009 398 0.017
intracellular signal transduction GO:0035556 314 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
negative regulation of metabolic process GO:0009892 331 0.017
proteolysis GO:0006508 175 0.017
Human
positive regulation of neuron projection development GO:0010976 99 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
positive regulation of protein modification process GO:0031401 142 0.017
single organism behavior GO:0044708 130 0.017
locomotion GO:0040011 237 0.017
circulatory system process GO:0003013 183 0.017
regulation of cellular localization GO:0060341 263 0.017
protein complex assembly GO:0006461 263 0.017
regulation of cellular component organization GO:0051128 368 0.016
regulation of cell differentiation GO:0045595 320 0.016
positive regulation of signaling GO:0023056 270 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
neurological system process GO:0050877 219 0.016
behavior GO:0007610 205 0.016
single organism organelle organization GO:1902589 180 0.016
spindle organization GO:0007051 2 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
macromolecule localization GO:0033036 252 0.016
regulation of secretion GO:0051046 224 0.016
positive regulation of gene expression GO:0010628 244 0.015
regulation of system process GO:0044057 208 0.015
cellular component morphogenesis GO:0032989 155 0.015
response to ketone GO:1901654 182 0.015
tissue development GO:0009888 252 0.015
positive regulation of cell development GO:0010720 176 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
regulation of neuron projection development GO:0010975 161 0.015
regulation of rna metabolic process GO:0051252 391 0.015
regulation of programmed cell death GO:0043067 341 0.015
regulation of protein metabolic process GO:0051246 289 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of membrane potential GO:0042391 110 0.015
cofactor metabolic process GO:0051186 95 0.014
single organism reproductive process GO:0044702 297 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
rna metabolic process GO:0016070 406 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
negative regulation of cell death GO:0060548 229 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
neuron development GO:0048666 286 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
synaptic transmission GO:0007268 235 0.014
peptidyl amino acid modification GO:0018193 126 0.014
protein complex biogenesis GO:0070271 263 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
membrane organization GO:0061024 94 0.014
cation homeostasis GO:0055080 195 0.014
dephosphorylation GO:0016311 98 0.014
multi organism reproductive process GO:0044703 262 0.014
cellular response to oxygen containing compound GO:1901701 386 0.013
signal release GO:0023061 145 0.013
response to growth factor GO:0070848 189 0.013
response to extracellular stimulus GO:0009991 380 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of hormone levels GO:0010817 187 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
response to peptide GO:1901652 292 0.013
regulation of cell development GO:0060284 263 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
adult locomotory behavior GO:0008344 4 0.013
chromosome segregation GO:0007059 2 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
regulation of nervous system development GO:0051960 264 0.013
purine containing compound metabolic process GO:0072521 253 0.013
cell cell signaling GO:0007267 335 0.013
regulation of neurogenesis GO:0050767 247 0.013
response to oxygen levels GO:0070482 265 0.013
nucleic acid templated transcription GO:0097659 379 0.013
blood circulation GO:0008015 183 0.012
coenzyme metabolic process GO:0006732 86 0.012
fatty acid metabolic process GO:0006631 99 0.012
ras protein signal transduction GO:0007265 29 0.012
nucleotide metabolic process GO:0009117 279 0.012
muscle system process GO:0003012 115 0.012
response to oxidative stress GO:0006979 186 0.012
immune system process GO:0002376 204 0.012
regulation of signal transduction GO:0009966 318 0.012
cytoplasmic transport GO:0016482 115 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
action potential GO:0001508 54 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
anion transport GO:0006820 178 0.012
regulation of catalytic activity GO:0050790 304 0.012
organic anion transport GO:0015711 132 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
epithelium development GO:0060429 96 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
central nervous system development GO:0007417 311 0.012
multicellular organism reproduction GO:0032504 233 0.012
head development GO:0060322 247 0.012
cell migration GO:0016477 197 0.012
ion homeostasis GO:0050801 212 0.011
brain development GO:0007420 247 0.011
aging GO:0007568 241 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
regulation of cell projection organization GO:0031344 175 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
metal ion homeostasis GO:0055065 186 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cellular chemical homeostasis GO:0055082 247 0.011
rna biosynthetic process GO:0032774 380 0.011
protein localization GO:0008104 191 0.011
lipid storage GO:0019915 1 0.011
response to decreased oxygen levels GO:0036293 237 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
response to wounding GO:0009611 254 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
transcription dna templated GO:0006351 377 0.011
positive regulation of cell death GO:0010942 184 0.011
axis specification GO:0009798 4 0.011
regulation of transporter activity GO:0032409 50 0.011
nucleoside catabolic process GO:0009164 126 0.011
amide transport GO:0042886 105 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
sensory organ development GO:0007423 74 0.011
small molecule catabolic process GO:0044282 59 0.010
lipid biosynthetic process GO:0008610 128 0.010
regulation of phosphorylation GO:0042325 248 0.010
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
regulation of transcription dna templated GO:0006355 374 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
cellular component movement GO:0006928 248 0.010
negative regulation of transport GO:0051051 136 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
protein oligomerization GO:0051259 191 0.010
nucleotide catabolic process GO:0009166 139 0.010
cellular response to external stimulus GO:0071496 118 0.010

Spg7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
Human
musculoskeletal system disease DOID:17 0 0.024
nervous system disease DOID:863 0 0.017
Human
central nervous system disease DOID:331 0 0.016
Human
muscular disease DOID:0080000 0 0.015
disease of metabolism DOID:0014667 0 0.013
myopathy DOID:423 0 0.012
muscle tissue disease DOID:66 0 0.012
inherited metabolic disorder DOID:655 0 0.011