Rattus norvegicus

0 known processes

Hps1

Hermansky-Pudlak syndrome 1 homolog (human)

(Aliases: Hps)

Hps1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.078
cellular component assembly GO:0022607 360 0.072
homeostatic process GO:0042592 331 0.069
regulation of programmed cell death GO:0043067 341 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.065
nucleobase containing small molecule metabolic process GO:0055086 316 0.061
cellular response to endogenous stimulus GO:0071495 377 0.060
carbohydrate derivative metabolic process GO:1901135 346 0.058
regulation of signal transduction GO:0009966 318 0.057
regulation of phosphate metabolic process GO:0019220 349 0.054
regulation of secretion GO:0051046 224 0.053
organelle organization GO:0006996 266 0.052
macromolecular complex subunit organization GO:0043933 339 0.051
positive regulation of developmental process GO:0051094 283 0.050
cellular amino acid metabolic process GO:0006520 107 0.048
multi organism reproductive process GO:0044703 262 0.048
nucleoside phosphate metabolic process GO:0006753 283 0.047
secretion GO:0046903 307 0.047
single organism reproductive process GO:0044702 297 0.047
regulation of molecular function GO:0065009 398 0.046
brain development GO:0007420 247 0.046
protein oligomerization GO:0051259 191 0.044
negative regulation of metabolic process GO:0009892 331 0.043
reproductive process GO:0022414 372 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
apoptotic process GO:0006915 381 0.041
cellular response to oxygen containing compound GO:1901701 386 0.040
response to hypoxia GO:0001666 231 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
response to inorganic substance GO:0010035 377 0.039
response to peptide hormone GO:0043434 278 0.039
cellular ion homeostasis GO:0006873 184 0.039
regulation of transcription dna templated GO:0006355 374 0.039
central nervous system development GO:0007417 311 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
positive regulation of response to stimulus GO:0048584 285 0.038
organophosphate metabolic process GO:0019637 370 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
multicellular organism reproduction GO:0032504 233 0.036
cellular chemical homeostasis GO:0055082 247 0.035
response to decreased oxygen levels GO:0036293 237 0.035
response to carbohydrate GO:0009743 183 0.034
nucleic acid templated transcription GO:0097659 379 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
transmembrane transport GO:0055085 412 0.034
regulation of cellular localization GO:0060341 263 0.034
chemical homeostasis GO:0048878 292 0.033
rna biosynthetic process GO:0032774 380 0.033
rna metabolic process GO:0016070 406 0.033
secretion by cell GO:0032940 248 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
single organism biosynthetic process GO:0044711 342 0.031
protein complex subunit organization GO:0071822 302 0.031
regulation of protein modification process GO:0031399 194 0.031
response to extracellular stimulus GO:0009991 380 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
ion homeostasis GO:0050801 212 0.031
cellular component biogenesis GO:0044085 368 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.030
regulation of catalytic activity GO:0050790 304 0.030
single organism organelle organization GO:1902589 180 0.029
regulation of protein metabolic process GO:0051246 289 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
neuron differentiation GO:0030182 368 0.029
regulation of cellular component organization GO:0051128 368 0.029
regulation of rna metabolic process GO:0051252 391 0.028
response to nutrient GO:0007584 248 0.028
regeneration GO:0031099 163 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
positive regulation of gene expression GO:0010628 244 0.028
head development GO:0060322 247 0.027
regulation of cell development GO:0060284 263 0.027
organic acid metabolic process GO:0006082 292 0.027
nucleotide metabolic process GO:0009117 279 0.027
regulation of apoptotic process GO:0042981 335 0.027
sensory organ development GO:0007423 74 0.026
intracellular signal transduction GO:0035556 314 0.026
positive regulation of cell communication GO:0010647 271 0.026
response to nutrient levels GO:0031667 370 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
macromolecular complex assembly GO:0065003 273 0.026
aging GO:0007568 241 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
protein complex assembly GO:0006461 263 0.026
positive regulation of cell death GO:0010942 184 0.026
cellular amine metabolic process GO:0044106 38 0.026
cation homeostasis GO:0055080 195 0.026
regulation of cell differentiation GO:0045595 320 0.026
neuron projection development GO:0031175 273 0.025
positive regulation of cell development GO:0010720 176 0.025
response to alkaloid GO:0043279 132 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
anion transport GO:0006820 178 0.025
transcription dna templated GO:0006351 377 0.025
negative regulation of gene expression GO:0010629 199 0.025
cellular cation homeostasis GO:0030003 180 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
muscle cell proliferation GO:0033002 84 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
ribonucleoside metabolic process GO:0009119 174 0.024
cellular homeostasis GO:0019725 252 0.024
amine metabolic process GO:0009308 38 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
embryonic pattern specification GO:0009880 1 0.024
rhythmic process GO:0048511 156 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
circulatory system process GO:0003013 183 0.023
protein phosphorylation GO:0006468 345 0.023
organ regeneration GO:0031100 101 0.023
cellular response to peptide GO:1901653 133 0.023
neurological system process GO:0050877 219 0.023
cell cell signaling GO:0007267 335 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
ion transmembrane transport GO:0034220 365 0.023
positive regulation of signaling GO:0023056 270 0.023
regulation of secretion by cell GO:1903530 208 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
programmed cell death GO:0012501 392 0.022
reproduction GO:0000003 245 0.022
cellular ketone metabolic process GO:0042180 51 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
negative regulation of signaling GO:0023057 157 0.022
growth GO:0040007 165 0.022
response to monosaccharide GO:0034284 159 0.021
negative regulation of molecular function GO:0044092 133 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
cellular catabolic process GO:0044248 295 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
protein heterooligomerization GO:0051291 89 0.021
positive regulation of molecular function GO:0044093 230 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
response to oxygen levels GO:0070482 265 0.021
positive regulation of nervous system development GO:0051962 178 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
blood circulation GO:0008015 183 0.020
oxoacid metabolic process GO:0043436 290 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
response to cytokine GO:0034097 215 0.020
positive regulation of signal transduction GO:0009967 175 0.020
proteolysis GO:0006508 175 0.020
cellular response to peptide hormone stimulus GO:0071375 120 0.020
nucleoside metabolic process GO:0009116 179 0.019
developmental process involved in reproduction GO:0003006 159 0.019
female gonad development GO:0008585 53 0.019
cell projection organization GO:0030030 302 0.019
regulation of cell proliferation GO:0042127 359 0.019
transmission of nerve impulse GO:0019226 42 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
protein complex biogenesis GO:0070271 263 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
negative regulation of cell death GO:0060548 229 0.019
response to acid chemical GO:0001101 222 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
defense response GO:0006952 194 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
development of primary sexual characteristics GO:0045137 107 0.019
regulation of nervous system development GO:0051960 264 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
oxidation reduction process GO:0055114 304 0.018
metal ion transport GO:0030001 289 0.018
telencephalon development GO:0021537 62 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
eye development GO:0001654 50 0.018
localization of cell GO:0051674 202 0.018
response to bacterium GO:0009617 200 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
synaptic transmission GO:0007268 235 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
eye morphogenesis GO:0048592 4 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
positive regulation of secretion by cell GO:1903532 128 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
forebrain development GO:0030900 98 0.017
regulation of neurogenesis GO:0050767 247 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
anterior posterior pattern specification GO:0009952 1 0.017
single organism intracellular transport GO:1902582 166 0.017
response to purine containing compound GO:0014074 126 0.017
cell migration GO:0016477 197 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
response to ketone GO:1901654 182 0.017
response to metal ion GO:0010038 253 0.017
neuron development GO:0048666 286 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
organic anion transport GO:0015711 132 0.017
wound healing GO:0042060 122 0.017
gland development GO:0048732 155 0.017
female sex differentiation GO:0046660 59 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
regulation of hydrolase activity GO:0051336 143 0.017
regulation of membrane potential GO:0042391 110 0.017
catabolic process GO:0009056 351 0.016
cellular response to stress GO:0033554 269 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
negative regulation of cell communication GO:0010648 158 0.016
cation transport GO:0006812 382 0.016
purine containing compound metabolic process GO:0072521 253 0.016
response to peptide GO:1901652 292 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
regulation of cell projection organization GO:0031344 175 0.016
response to hexose GO:0009746 144 0.016
biological adhesion GO:0022610 110 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
regulation of system process GO:0044057 208 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
response to biotic stimulus GO:0009607 226 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
sexual reproduction GO:0019953 148 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
metal ion homeostasis GO:0055065 186 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
response to external biotic stimulus GO:0043207 221 0.015
locomotion GO:0040011 237 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
cardiovascular system development GO:0072358 134 0.015
response to growth factor GO:0070848 189 0.015
camera type eye development GO:0043010 48 0.015
positive regulation of secretion GO:0051047 140 0.015
organic substance catabolic process GO:1901575 316 0.015
multicellular organism growth GO:0035264 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
response to wounding GO:0009611 254 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
jak stat cascade GO:0007259 26 0.014
regulation of anatomical structure size GO:0090066 135 0.014
sex differentiation GO:0007548 113 0.014
tissue development GO:0009888 252 0.014
response to radiation GO:0009314 137 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
regulation of neuron differentiation GO:0045664 208 0.014
liver development GO:0001889 90 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
response to other organism GO:0051707 220 0.014
response to vitamin GO:0033273 131 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
regulation of neuron projection development GO:0010975 161 0.014
purine containing compound catabolic process GO:0072523 138 0.013
vesicle mediated transport GO:0016192 181 0.013
response to glucose GO:0009749 136 0.013
learning or memory GO:0007611 90 0.013
signal release GO:0023061 145 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
cell type specific apoptotic process GO:0097285 134 0.013
reproductive system development GO:0061458 128 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
vasculogenesis GO:0001570 3 0.013
response to toxic substance GO:0009636 133 0.013
embryonic skeletal system development GO:0048706 3 0.013
cellular component morphogenesis GO:0032989 155 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
reproductive structure development GO:0048608 128 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
gamete generation GO:0007276 124 0.013
intracellular transport GO:0046907 185 0.013
regulation of phosphorylation GO:0042325 248 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
organophosphate catabolic process GO:0046434 148 0.013
neuron projection morphogenesis GO:0048812 122 0.013
positive regulation of transport GO:0051050 245 0.013
carbohydrate metabolic process GO:0005975 130 0.013
cellular response to lipid GO:0071396 201 0.012
salivary gland development GO:0007431 3 0.012
dendrite development GO:0016358 72 0.012
negative regulation of developmental process GO:0051093 125 0.012
axis specification GO:0009798 4 0.012
single organism catabolic process GO:0044712 283 0.012
calcium ion homeostasis GO:0055074 162 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
regulation of homeostatic process GO:0032844 101 0.012
ras protein signal transduction GO:0007265 29 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
cell motility GO:0048870 202 0.012
epithelial cell differentiation GO:0030855 71 0.012
single organism behavior GO:0044708 130 0.012
macromolecule localization GO:0033036 252 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
nucleotide catabolic process GO:0009166 139 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
axon development GO:0061564 96 0.012
ovulation cycle GO:0042698 67 0.012
female pregnancy GO:0007565 122 0.012
response to ethanol GO:0045471 162 0.012
circulatory system development GO:0072359 134 0.012
negative regulation of signal transduction GO:0009968 83 0.012
cognition GO:0050890 92 0.012
cellular component movement GO:0006928 248 0.012
appendage morphogenesis GO:0035107 4 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
gastrulation GO:0007369 2 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
protein homooligomerization GO:0051260 91 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
single organism membrane organization GO:0044802 74 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
lipid storage GO:0019915 1 0.011
ovulation cycle process GO:0022602 50 0.011
immune system process GO:0002376 204 0.011
male sex differentiation GO:0046661 64 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
actin filament based process GO:0030029 86 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
nucleoside catabolic process GO:0009164 126 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
divalent inorganic cation transport GO:0072511 134 0.011
behavior GO:0007610 205 0.011
response to estrogen GO:0043627 232 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
organ morphogenesis GO:0009887 75 0.011
cell morphogenesis GO:0000902 142 0.011
negative regulation of transport GO:0051051 136 0.011
memory GO:0007613 54 0.011
interleukin 1 beta secretion GO:0050702 3 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
regulation of interleukin 1 secretion GO:0050704 3 0.011
embryonic axis specification GO:0000578 1 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
regulation of hormone levels GO:0010817 187 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
neuronal action potential GO:0019228 35 0.010
regulation of blood circulation GO:1903522 110 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
regulation of blood vessel size GO:0050880 89 0.010
response to organophosphorus GO:0046683 102 0.010
multicellular organismal signaling GO:0035637 44 0.010
action potential GO:0001508 54 0.010
lipid metabolic process GO:0006629 283 0.010
cofactor metabolic process GO:0051186 95 0.010

Hps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.016
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.011