Rattus norvegicus

0 known processes

Hps3

Hermansky-Pudlak syndrome 3 homolog (human)

Hps3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 208 0.079
response to nutrient levels GO:0031667 370 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.064
regulation of catalytic activity GO:0050790 304 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.055
organophosphate metabolic process GO:0019637 370 0.054
regulation of phosphorus metabolic process GO:0051174 349 0.054
response to decreased oxygen levels GO:0036293 237 0.050
lipid metabolic process GO:0006629 283 0.048
response to acid chemical GO:0001101 222 0.046
organelle organization GO:0006996 266 0.046
response to extracellular stimulus GO:0009991 380 0.044
single organism catabolic process GO:0044712 283 0.042
response to oxygen levels GO:0070482 265 0.040
regulation of phosphate metabolic process GO:0019220 349 0.039
cation transmembrane transport GO:0098655 263 0.038
phosphatidylinositol dephosphorylation GO:0046856 4 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
cellular component biogenesis GO:0044085 368 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
oxidation reduction process GO:0055114 304 0.035
amine metabolic process GO:0009308 38 0.034
regulation of signal transduction GO:0009966 318 0.033
transmembrane transport GO:0055085 412 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
regulation of molecular function GO:0065009 398 0.031
ras protein signal transduction GO:0007265 29 0.031
ribose phosphate metabolic process GO:0019693 235 0.031
cellular response to endogenous stimulus GO:0071495 377 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
oxoacid metabolic process GO:0043436 290 0.030
nucleotide metabolic process GO:0009117 279 0.030
rna metabolic process GO:0016070 406 0.029
single organism cellular localization GO:1902580 102 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
dephosphorylation GO:0016311 98 0.028
cellular response to stress GO:0033554 269 0.028
response to hypoxia GO:0001666 231 0.028
negative regulation of phosphorus metabolic process GO:0010563 80 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
negative regulation of metabolic process GO:0009892 331 0.027
ion transmembrane transport GO:0034220 365 0.027
negative regulation of cell death GO:0060548 229 0.027
protein phosphorylation GO:0006468 345 0.027
single organism biosynthetic process GO:0044711 342 0.026
endocytosis GO:0006897 84 0.025
response to vitamin GO:0033273 131 0.025
transcription dna templated GO:0006351 377 0.025
regulation of phosphorylation GO:0042325 248 0.024
intracellular signal transduction GO:0035556 314 0.024
negative regulation of phosphate metabolic process GO:0045936 80 0.024
response to corticosteroid GO:0031960 235 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
vesicle mediated transport GO:0016192 181 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
organic acid metabolic process GO:0006082 292 0.023
cellular amine metabolic process GO:0044106 38 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
response to cytokine GO:0034097 215 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
regulation of cellular localization GO:0060341 263 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
response to toxic substance GO:0009636 133 0.021
response to glucocorticoid GO:0051384 223 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
cellular protein localization GO:0034613 122 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
response to nutrient GO:0007584 248 0.021
intracellular transport GO:0046907 185 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
cytoskeleton organization GO:0007010 111 0.021
chemical homeostasis GO:0048878 292 0.020
protein oligomerization GO:0051259 191 0.020
homeostatic process GO:0042592 331 0.020
response to metal ion GO:0010038 253 0.020
response to peptide hormone GO:0043434 278 0.020
organophosphate catabolic process GO:0046434 148 0.019
cellular component assembly GO:0022607 360 0.019
macromolecular complex assembly GO:0065003 273 0.019
central nervous system development GO:0007417 311 0.019
single organism organelle organization GO:1902589 180 0.019
catabolic process GO:0009056 351 0.019
neurological system process GO:0050877 219 0.018
response to inorganic substance GO:0010035 377 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
gamete generation GO:0007276 124 0.018
regulation of protein metabolic process GO:0051246 289 0.018
response to estrogen GO:0043627 232 0.018
cellular component morphogenesis GO:0032989 155 0.018
proteolysis GO:0006508 175 0.018
muscle system process GO:0003012 115 0.018
reactive oxygen species metabolic process GO:0072593 37 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
rna biosynthetic process GO:0032774 380 0.017
regulation of anatomical structure size GO:0090066 135 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
positive regulation of molecular function GO:0044093 230 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
phospholipid metabolic process GO:0006644 61 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
single organism reproductive process GO:0044702 297 0.017
neuron development GO:0048666 286 0.017
single organism intracellular transport GO:1902582 166 0.016
protein complex biogenesis GO:0070271 263 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
negative regulation of phosphorylation GO:0042326 57 0.016
macromolecule localization GO:0033036 252 0.016
regulation of hydrolase activity GO:0051336 143 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.016
protein localization to organelle GO:0033365 57 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
protein complex assembly GO:0006461 263 0.016
regulation of transcription dna templated GO:0006355 374 0.016
positive regulation of hydrolase activity GO:0051345 86 0.016
cellular response to external stimulus GO:0071496 118 0.016
cellular homeostasis GO:0019725 252 0.016
negative regulation of protein phosphorylation GO:0001933 44 0.016
response to amino acid GO:0043200 75 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
cellular response to peptide hormone stimulus GO:0071375 120 0.016
nitrogen compound transport GO:0071705 229 0.015
relaxation of muscle GO:0090075 4 0.015
response to estradiol GO:0032355 164 0.015
cellular catabolic process GO:0044248 295 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cell projection organization GO:0030030 302 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
secretion GO:0046903 307 0.015
nucleic acid templated transcription GO:0097659 379 0.015
cell growth GO:0016049 104 0.015
neuron differentiation GO:0030182 368 0.015
response to retinoic acid GO:0032526 63 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
response to osmotic stress GO:0006970 42 0.015
positive regulation of nervous system development GO:0051962 178 0.015
purine containing compound metabolic process GO:0072521 253 0.015
cation transport GO:0006812 382 0.015
response to growth factor GO:0070848 189 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
protein complex subunit organization GO:0071822 302 0.015
regulation of multicellular organismal development GO:2000026 376 0.014
regeneration GO:0031099 163 0.014
peptide transport GO:0015833 97 0.014
regulation of rna metabolic process GO:0051252 391 0.014
eye morphogenesis GO:0048592 4 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
behavioral response to ethanol GO:0048149 1 0.014
cellular component movement GO:0006928 248 0.014
protein heterooligomerization GO:0051291 89 0.014
negative regulation of molecular function GO:0044092 133 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
amide transport GO:0042886 105 0.014
axon cargo transport GO:0008088 1 0.014
regulation of system process GO:0044057 208 0.014
alcohol metabolic process GO:0006066 77 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
cytoplasmic transport GO:0016482 115 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
actin cytoskeleton organization GO:0030036 73 0.014
regulation of nervous system development GO:0051960 264 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of protein kinase activity GO:0045859 105 0.013
male gamete generation GO:0048232 99 0.013
response to monosaccharide GO:0034284 159 0.013
regulation of cell differentiation GO:0045595 320 0.013
reproduction GO:0000003 245 0.013
regulation of cellular component organization GO:0051128 368 0.013
regulation of hormone levels GO:0010817 187 0.013
synaptic vesicle endocytosis GO:0048488 4 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of transferase activity GO:0051338 123 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular response to nutrient levels GO:0031669 60 0.013
response to carbohydrate GO:0009743 183 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
cellular response to lipid GO:0071396 201 0.013
positive regulation of gene expression GO:0010628 244 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
lipid biosynthetic process GO:0008610 128 0.012
regulation of kinase activity GO:0043549 117 0.012
cell cell signaling GO:0007267 335 0.012
macroautophagy GO:0016236 4 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
anion transport GO:0006820 178 0.012
regulation of catabolic process GO:0009894 113 0.012
organic hydroxy compound transport GO:0015850 77 0.012
fatty acid metabolic process GO:0006631 99 0.012
multi organism reproductive process GO:0044703 262 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
positive regulation of transport GO:0051050 245 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
cellular response to peptide GO:1901653 133 0.012
small molecule biosynthetic process GO:0044283 124 0.012
response to peptide GO:1901652 292 0.012
regulation of programmed cell death GO:0043067 341 0.012
cellular chemical homeostasis GO:0055082 247 0.012
aging GO:0007568 241 0.012
synaptic vesicle priming GO:0016082 4 0.012
mapk cascade GO:0000165 140 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of neurogenesis GO:0050767 247 0.012
sequestering of metal ion GO:0051238 9 0.012
actin filament based process GO:0030029 86 0.012
neuron projection development GO:0031175 273 0.012
maintenance of location GO:0051235 17 0.012
blood circulation GO:0008015 183 0.011
response to glucose GO:0009749 136 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
secretion by cell GO:0032940 248 0.011
circulatory system process GO:0003013 183 0.011
neuron projection morphogenesis GO:0048812 122 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
lipid modification GO:0030258 52 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
reproductive process GO:0022414 372 0.011
response to hexose GO:0009746 144 0.011
apoptotic process GO:0006915 381 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
behavior GO:0007610 205 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
positive regulation of signal transduction GO:0009967 175 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
peptide hormone secretion GO:0030072 84 0.011
response to starvation GO:0042594 59 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
organic acid transport GO:0015849 116 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
hormone transport GO:0009914 121 0.011
chromosome segregation GO:0007059 2 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
regulation of body fluid levels GO:0050878 90 0.010
muscle contraction GO:0006936 88 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
metal ion transport GO:0030001 289 0.010
positive regulation of transcription factor import into nucleus GO:0042993 4 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
small molecule catabolic process GO:0044282 59 0.010
sexual reproduction GO:0019953 148 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
organic substance catabolic process GO:1901575 316 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
immune system process GO:0002376 204 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
peptide secretion GO:0002790 86 0.010
positive regulation of cell development GO:0010720 176 0.010
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010

Hps3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
central nervous system disease DOID:331 0 0.014
primary immunodeficiency disease DOID:612 0 0.012
severe combined immunodeficiency DOID:627 0 0.012
combined t cell and b cell immunodeficiency DOID:628 0 0.012
immune system disease DOID:2914 0 0.012
sensory system disease DOID:0050155 0 0.011