Rattus norvegicus

33 known processes

Ldlr

low density lipoprotein receptor

(Aliases: LDLRA)

Ldlr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of peptide transport GO:0090087 87 0.143
cell projection organization GO:0030030 302 0.138
Fly
cell cell signaling GO:0007267 335 0.125
secretion GO:0046903 307 0.116
regulation of cellular component organization GO:0051128 368 0.100
regulation of secretion GO:0051046 224 0.086
regulation of nucleic acid templated transcription GO:1903506 380 0.082
organic hydroxy compound metabolic process GO:1901615 115 0.082
Mouse
regulation of secretion by cell GO:1903530 208 0.081
rhythmic process GO:0048511 156 0.081
negative regulation of cellular metabolic process GO:0031324 281 0.077
regulation of cell differentiation GO:0045595 320 0.077
regulation of hormone levels GO:0010817 187 0.076
lipid biosynthetic process GO:0008610 128 0.076
Mouse
behavior GO:0007610 205 0.076
negative regulation of multicellular organismal process GO:0051241 203 0.073
cellular response to oxygen containing compound GO:1901701 386 0.073
Rat
neuron development GO:0048666 286 0.073
Fly
programmed cell death GO:0012501 392 0.073
cell projection morphogenesis GO:0048858 123 0.072
Fly
multicellular organism growth GO:0035264 1 0.072
regulation of smooth muscle cell proliferation GO:0048660 75 0.071
positive regulation of catalytic activity GO:0043085 184 0.071
regulation of response to external stimulus GO:0032101 106 0.070
signal release GO:0023061 145 0.069
anatomical structure morphogenesis GO:0009653 298 0.069
Fly
cellular component biogenesis GO:0044085 368 0.068
synaptic transmission GO:0007268 235 0.068
regulation of phosphate metabolic process GO:0019220 349 0.067
Mouse
regulation of catalytic activity GO:0050790 304 0.067
locomotion GO:0040011 237 0.066
multi organism reproductive process GO:0044703 262 0.064
regulation of programmed cell death GO:0043067 341 0.064
lipid metabolic process GO:0006629 283 0.064
Mouse
response to glucocorticoid GO:0051384 223 0.064
negative regulation of metabolic process GO:0009892 331 0.063
vesicle mediated transport GO:0016192 181 0.062
hormone transport GO:0009914 121 0.061
apoptotic process GO:0006915 381 0.061
negative regulation of programmed cell death GO:0043069 183 0.061
response to nutrient GO:0007584 248 0.061
Rat
negative regulation of cell death GO:0060548 229 0.059
response to insulin GO:0032868 133 0.058
Rat
response to inorganic substance GO:0010035 377 0.058
regulation of molecular function GO:0065009 398 0.057
neuron projection development GO:0031175 273 0.057
Fly
regulation of cell proliferation GO:0042127 359 0.056
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.054
positive regulation of cell communication GO:0010647 271 0.054
ion transmembrane transport GO:0034220 365 0.054
reproductive process GO:0022414 372 0.053
negative regulation of gene expression GO:0010629 199 0.053
negative regulation of transport GO:0051051 136 0.053
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.052
small molecule biosynthetic process GO:0044283 124 0.052
transcription dna templated GO:0006351 377 0.051
response to nutrient levels GO:0031667 370 0.051
Rat
response to extracellular stimulus GO:0009991 380 0.051
Rat
rna metabolic process GO:0016070 406 0.050
regulation of neuron death GO:1901214 115 0.048
response to monosaccharide GO:0034284 159 0.048
coenzyme metabolic process GO:0006732 86 0.048
signal transduction by phosphorylation GO:0023014 144 0.047
organelle organization GO:0006996 266 0.047
neuron differentiation GO:0030182 368 0.047
Fly
peptide transport GO:0015833 97 0.046
regulation of transcription dna templated GO:0006355 374 0.046
response to peptide hormone GO:0043434 278 0.044
negative regulation of cellular biosynthetic process GO:0031327 161 0.043
rna biosynthetic process GO:0032774 380 0.043
regeneration GO:0031099 163 0.043
negative regulation of biosynthetic process GO:0009890 168 0.043
response to purine containing compound GO:0014074 126 0.043
negative regulation of transcription dna templated GO:0045892 116 0.042
nucleic acid templated transcription GO:0097659 379 0.042
response to corticosteroid GO:0031960 235 0.042
regulation of apoptotic process GO:0042981 335 0.041
neuron projection morphogenesis GO:0048812 122 0.041
Fly
reproductive system development GO:0061458 128 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.040
secretion by cell GO:0032940 248 0.040
monocarboxylic acid transport GO:0015718 52 0.040
regulation of hormone secretion GO:0046883 106 0.040
muscle cell proliferation GO:0033002 84 0.040
nitrogen compound transport GO:0071705 229 0.039
cellular response to stress GO:0033554 269 0.039
Rat
multi multicellular organism process GO:0044706 138 0.039
regulation of cellular protein metabolic process GO:0032268 267 0.039
reproductive structure development GO:0048608 128 0.039
cellular ketone metabolic process GO:0042180 51 0.039
positive regulation of locomotion GO:0040017 102 0.038
response to estrogen GO:0043627 232 0.038
dendrite development GO:0016358 72 0.038
cellular response to hormone stimulus GO:0032870 247 0.038
Rat
response to glucose GO:0009749 136 0.037
circadian regulation of gene expression GO:0032922 3 0.037
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
oxoacid metabolic process GO:0043436 290 0.036
response to carbohydrate GO:0009743 183 0.035
hormone secretion GO:0046879 115 0.035
transcription from rna polymerase ii promoter GO:0006366 252 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.034
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.034
regulation of system process GO:0044057 208 0.034
intracellular signal transduction GO:0035556 314 0.034
cellular metal ion homeostasis GO:0006875 172 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.033
carboxylic acid transport GO:0046942 115 0.033
single organism reproductive process GO:0044702 297 0.033
negative regulation of rna metabolic process GO:0051253 123 0.033
organic acid metabolic process GO:0006082 292 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.033
response to estradiol GO:0032355 164 0.032
regulation of protein kinase activity GO:0045859 105 0.032
inorganic ion transmembrane transport GO:0098660 229 0.032
glandular epithelial cell differentiation GO:0002067 4 0.032
dendrite morphogenesis GO:0048813 43 0.032
cellular component morphogenesis GO:0032989 155 0.032
Fly
regulation of kinase activity GO:0043549 117 0.032
regulation of vesicle mediated transport GO:0060627 81 0.032
regulation of peptide secretion GO:0002791 82 0.031
response to hexose GO:0009746 144 0.031
gland development GO:0048732 155 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
positive regulation of cell differentiation GO:0045597 217 0.030
regulation of fatty acid transport GO:2000191 10 0.030
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
amide transport GO:0042886 105 0.030
regulation of mapk cascade GO:0043408 116 0.030
cellular amine metabolic process GO:0044106 38 0.030
Mouse
macromolecular complex subunit organization GO:0043933 339 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
positive regulation of signaling GO:0023056 270 0.030
heart morphogenesis GO:0003007 3 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
cellular homeostasis GO:0019725 252 0.029
regulation of protein phosphorylation GO:0001932 183 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
organ morphogenesis GO:0009887 75 0.029
endocytosis GO:0006897 84 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
regulation of dendrite development GO:0050773 59 0.028
cellular lipid metabolic process GO:0044255 208 0.028
Mouse
regulation of cellular response to stress GO:0080135 49 0.028
peptide hormone secretion GO:0030072 84 0.028
protein phosphorylation GO:0006468 345 0.028
response to metal ion GO:0010038 253 0.028
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
steroid biosynthetic process GO:0006694 48 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
anion transport GO:0006820 178 0.027
Mouse
wound healing GO:0042060 122 0.027
regulation of rna metabolic process GO:0051252 391 0.027
cellular response to lipid GO:0071396 201 0.027
Rat
camera type eye development GO:0043010 48 0.027
regulation of synaptic transmission GO:0050804 141 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
central nervous system development GO:0007417 311 0.027
Rat
carboxylic acid metabolic process GO:0019752 289 0.027
smooth muscle cell proliferation GO:0048659 77 0.026
tissue development GO:0009888 252 0.026
response to oxygen levels GO:0070482 265 0.026
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.026
single organism biosynthetic process GO:0044711 342 0.026
Mouse
organic anion transport GO:0015711 132 0.026
Mouse
oxidation reduction process GO:0055114 304 0.025
negative regulation of cell differentiation GO:0045596 99 0.025
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.025
Mouse
ion homeostasis GO:0050801 212 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
Mouse
neurological system process GO:0050877 219 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
response to wounding GO:0009611 254 0.025
response to peptide GO:1901652 292 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
protein complex subunit organization GO:0071822 302 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
response to ethanol GO:0045471 162 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of cell motility GO:2000145 131 0.024
single organism behavior GO:0044708 130 0.024
regulation of cell projection organization GO:0031344 175 0.024
organ regeneration GO:0031100 101 0.024
catabolic process GO:0009056 351 0.024
Mouse
cellular component assembly GO:0022607 360 0.023
regulation of cellular component biogenesis GO:0044087 86 0.023
regulation of protein modification process GO:0031399 194 0.023
reproduction GO:0000003 245 0.023
positive regulation of molecular function GO:0044093 230 0.023
response to light stimulus GO:0009416 52 0.023
proteolysis GO:0006508 175 0.023
positive regulation of developmental process GO:0051094 283 0.023
cellular ion homeostasis GO:0006873 184 0.023
protein autophosphorylation GO:0046777 66 0.022
regulation of neuron projection development GO:0010975 161 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
circadian rhythm GO:0007623 88 0.022
positive regulation of transferase activity GO:0051347 81 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.022
single organism organelle organization GO:1902589 180 0.022
insulin secretion GO:0030073 69 0.022
placenta development GO:0001890 22 0.022
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
regulation of phosphorylation GO:0042325 248 0.021
organic substance catabolic process GO:1901575 316 0.021
Mouse
response to molecule of bacterial origin GO:0002237 194 0.021
Rat
regulation of cell migration GO:0030334 128 0.021
stress activated mapk cascade GO:0051403 35 0.021
microvillus assembly GO:0030033 2 0.021
regulation of map kinase activity GO:0043405 53 0.021
regulation of dendrite morphogenesis GO:0048814 33 0.021
transforming growth factor beta3 production GO:0032907 2 0.021
skeletal muscle tissue development GO:0007519 31 0.021
response to cytokine GO:0034097 215 0.021
Rat
positive regulation of mapk cascade GO:0043410 92 0.020
protein complex assembly GO:0006461 263 0.020
regulation of membrane potential GO:0042391 110 0.020
alcohol metabolic process GO:0006066 77 0.020
Mouse
anion transmembrane transport GO:0098656 77 0.020
cellular component movement GO:0006928 248 0.020
regulation of protein metabolic process GO:0051246 289 0.020
transmission of nerve impulse GO:0019226 42 0.020
negative regulation of protein import into nucleus translocation GO:0033159 1 0.020
response to ketone GO:1901654 182 0.020
homeostatic process GO:0042592 331 0.020
Human Mouse
negative regulation of phosphorus metabolic process GO:0010563 80 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
regulation of cellular localization GO:0060341 263 0.020
response to external biotic stimulus GO:0043207 221 0.020
Rat
peptide secretion GO:0002790 86 0.020
transmembrane transport GO:0055085 412 0.020
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.019
olfactory learning GO:0008355 1 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
regulation of mesenchymal cell proliferation GO:0010464 4 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
response to other organism GO:0051707 220 0.019
Rat
embryonic cranial skeleton morphogenesis GO:0048701 2 0.019
positive regulation of secretion GO:0051047 140 0.019
amine metabolic process GO:0009308 38 0.019
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
sensory organ development GO:0007423 74 0.019
cell part morphogenesis GO:0032990 123 0.019
Fly
actin cytoskeleton organization GO:0030036 73 0.019
olfactory bulb interneuron differentiation GO:0021889 1 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
Mouse
response to bacterium GO:0009617 200 0.019
Rat
lipid modification GO:0030258 52 0.019
regulation of cellular component movement GO:0051270 150 0.019
mapk cascade GO:0000165 140 0.019
sexual reproduction GO:0019953 148 0.018
positive regulation of protein modification process GO:0031401 142 0.018
response to hypoxia GO:0001666 231 0.018
multicellular organism reproduction GO:0032504 233 0.018
axis specification GO:0009798 4 0.018
jnk cascade GO:0007254 28 0.018
response to lipopolysaccharide GO:0032496 191 0.018
Rat
neuron death GO:0070997 127 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
positive regulation of transport GO:0051050 245 0.018
aging GO:0007568 241 0.018
regulation of neuron differentiation GO:0045664 208 0.018
negative regulation of signaling GO:0023057 157 0.018
negative regulation of molecular function GO:0044092 133 0.018
regulation of activation of jak2 kinase activity GO:0010534 1 0.017
stress activated protein kinase signaling cascade GO:0031098 37 0.017
positive regulation of signal transduction GO:0009967 175 0.017
localization of cell GO:0051674 202 0.017
glial cell differentiation GO:0010001 65 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
cellular response to insulin stimulus GO:0032869 81 0.017
Rat
protein complex biogenesis GO:0070271 263 0.017
response to organophosphorus GO:0046683 102 0.017
response to temperature stimulus GO:0009266 94 0.017
regulation of signal transduction GO:0009966 318 0.017
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.017
neuronal action potential GO:0019228 35 0.016
metal ion transport GO:0030001 289 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
Rat
inner ear morphogenesis GO:0042472 1 0.016
pancreatic stellate cell proliferation GO:0072343 2 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
regulation of response to stress GO:0080134 126 0.016
developmental process involved in reproduction GO:0003006 159 0.016
tube development GO:0035295 89 0.016
peptidyl amino acid modification GO:0018193 126 0.016
cofactor metabolic process GO:0051186 95 0.016
positive regulation of dendrite development GO:1900006 35 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
acetyl coa metabolic process GO:0006084 17 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
positive regulation of peptide secretion GO:0002793 52 0.016
negative regulation of cell communication GO:0010648 158 0.016
regulation of homeostatic process GO:0032844 101 0.016
Mouse
response to acid chemical GO:0001101 222 0.016
positive regulation of cell death GO:0010942 184 0.015
response to decreased oxygen levels GO:0036293 237 0.015
regulation of anatomical structure size GO:0090066 135 0.015
muscle structure development GO:0061061 87 0.015
organelle localization GO:0051640 55 0.015
brain development GO:0007420 247 0.015
Rat
entrainment of circadian clock GO:0009649 3 0.015
embryo development GO:0009790 49 0.015
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.015
regulation of peptide hormone secretion GO:0090276 80 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
Mouse
regulation of protein serine threonine kinase activity GO:0071900 64 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
cellular chemical homeostasis GO:0055082 247 0.015
chemical homeostasis GO:0048878 292 0.015
Human Mouse
regulation of cell morphogenesis GO:0022604 77 0.015
female pregnancy GO:0007565 122 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
embryonic pattern specification GO:0009880 1 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
positive regulation of gene expression GO:0010628 244 0.015
cellular response to nitrite GO:0071250 2 0.015
response to activity GO:0014823 73 0.015
regulation of transferase activity GO:0051338 123 0.015
response to vitamin GO:0033273 131 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
neuromuscular process GO:0050905 2 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
neuron projection regeneration GO:0031102 35 0.014
fatty acid metabolic process GO:0006631 99 0.014
establishment of organelle localization GO:0051656 37 0.014
developmental growth involved in morphogenesis GO:0060560 33 0.014
liver development GO:0001889 90 0.014
camera type eye morphogenesis GO:0048593 2 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
sensory perception GO:0007600 101 0.014
response to growth factor GO:0070848 189 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
cell growth GO:0016049 104 0.014
positive regulation of defense response GO:0031349 37 0.014
spindle organization GO:0007051 2 0.014
regulation of growth GO:0040008 105 0.014
organic hydroxy compound biosynthetic process GO:1901617 51 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
cellular response to alcohol GO:0097306 87 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
macromolecular complex assembly GO:0065003 273 0.014
cellular cation homeostasis GO:0030003 180 0.013
activation of jak2 kinase activity GO:0042977 2 0.013
head development GO:0060322 247 0.013
Rat
nucleotide metabolic process GO:0009117 279 0.013
response to mechanical stimulus GO:0009612 134 0.013
growth GO:0040007 165 0.013
positive regulation of sodium ion transmembrane transporter activity GO:2000651 1 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
Rat
negative regulation of growth GO:0045926 37 0.013
positive regulation of nervous system development GO:0051962 178 0.013
endochondral bone growth GO:0003416 3 0.013
response to oxidative stress GO:0006979 186 0.013
regulation of smoothened signaling pathway GO:0008589 2 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.013
postnatal olfactory bulb interneuron migration GO:0021827 1 0.013
heart development GO:0007507 72 0.013
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
hepaticobiliary system development GO:0061008 90 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
Mouse
muscle cell differentiation GO:0042692 52 0.013
fatty acid oxidation GO:0019395 29 0.013
salivary gland development GO:0007431 3 0.013
embryonic neurocranium morphogenesis GO:0048702 2 0.013
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.013
regulation of triglyceride biosynthetic process GO:0010866 4 0.013
Mouse
regulation of behavior GO:0050795 61 0.013
regulation of cellular component size GO:0032535 51 0.013
mammary gland development GO:0030879 38 0.013
positive regulation of response to wounding GO:1903036 34 0.013
protein oligomerization GO:0051259 191 0.013
regulation of insulin secretion GO:0050796 65 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
circulatory system process GO:0003013 183 0.013
exocytosis GO:0006887 60 0.013
intracellular transport GO:0046907 185 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
Mouse
organic acid transport GO:0015849 116 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
odontogenesis GO:0042476 32 0.012
glucan biosynthetic process GO:0009250 15 0.012
calcium ion transport GO:0006816 131 0.012
positive regulation of dendritic spine morphogenesis GO:0061003 3 0.012
gliogenesis GO:0042063 93 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
negative regulation of nervous system development GO:0051961 79 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
response to radiation GO:0009314 137 0.012
eye morphogenesis GO:0048592 4 0.012
nucleoside metabolic process GO:0009116 179 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
male gamete generation GO:0048232 99 0.012
negative regulation of phosphorylation GO:0042326 57 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
hexose metabolic process GO:0019318 58 0.012
activation of phospholipase d activity GO:0031584 2 0.012
gastrulation GO:0007369 2 0.012
response to food GO:0032094 27 0.012
response to alkaloid GO:0043279 132 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
mammary gland epithelium development GO:0061180 1 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
negative regulation of cell development GO:0010721 82 0.012
organic acid biosynthetic process GO:0016053 83 0.012
cardiac ventricle development GO:0003231 1 0.012
vesicle localization GO:0051648 33 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
positive regulation of dendrite morphogenesis GO:0050775 21 0.012
fatty acid transport GO:0015908 25 0.012
response to reactive oxygen species GO:0000302 120 0.012
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.012
lipid storage GO:0019915 1 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
Rat
chemosensory behavior GO:0007635 2 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
single organism catabolic process GO:0044712 283 0.011
Mouse
ephrin receptor signaling pathway GO:0048013 3 0.011
positive regulation of receptor activity GO:2000273 4 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
macrophage chemotaxis GO:0048246 2 0.011
mesoderm development GO:0007498 2 0.011
aromatic compound catabolic process GO:0019439 168 0.011
hindbrain morphogenesis GO:0021575 2 0.011
detection of visible light GO:0009584 3 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
regulation of cell development GO:0060284 263 0.011
hormone metabolic process GO:0042445 69 0.011
positive regulation of cell motility GO:2000147 97 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
behavioral response to nicotine GO:0035095 2 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
activation of protein kinase activity GO:0032147 47 0.011
negative regulation of secretion GO:0051048 82 0.011
adult locomotory behavior GO:0008344 4 0.011
cellular polysaccharide biosynthetic process GO:0033692 15 0.011
ras protein signal transduction GO:0007265 29 0.011
cardiac muscle tissue morphogenesis GO:0055008 1 0.011
synaptic vesicle endocytosis GO:0048488 4 0.011
energy derivation by oxidation of organic compounds GO:0015980 46 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.011
cell motility GO:0048870 202 0.011
lung development GO:0030324 43 0.011
regulation of transforming growth factor beta3 production GO:0032910 2 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
protein maturation GO:0051604 68 0.011
tube morphogenesis GO:0035239 23 0.011

Ldlr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.054
Human
disease of anatomical entity DOID:7 0 0.053
musculoskeletal system disease DOID:17 0 0.053
connective tissue disease DOID:65 0 0.042
bone disease DOID:0080001 0 0.018
gastrointestinal system cancer DOID:3119 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
nervous system disease DOID:863 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
carbohydrate metabolic disorder DOID:2978 0 0.011
inherited metabolic disorder DOID:655 0 0.011
Human
stomach cancer DOID:10534 0 0.011
neuromuscular disease DOID:440 0 0.011
neuropathy DOID:870 0 0.011