Rattus norvegicus

0 known processes

Fkbp5

FK506 binding protein 5

Fkbp5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 252 0.118
regulation of rna biosynthetic process GO:2001141 381 0.118
rna metabolic process GO:0016070 406 0.112
negative regulation of macromolecule metabolic process GO:0010605 260 0.098
nucleic acid templated transcription GO:0097659 379 0.094
transcription dna templated GO:0006351 377 0.091
negative regulation of metabolic process GO:0009892 331 0.087
carboxylic acid metabolic process GO:0019752 289 0.086
cellular amino acid metabolic process GO:0006520 107 0.078
regulation of molecular function GO:0065009 398 0.075
negative regulation of biosynthetic process GO:0009890 168 0.070
regulation of nucleic acid templated transcription GO:1903506 380 0.070
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.069
cellular ketone metabolic process GO:0042180 51 0.069
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.067
oxoacid metabolic process GO:0043436 290 0.063
organic acid metabolic process GO:0006082 292 0.061
amine metabolic process GO:0009308 38 0.057
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.057
catabolic process GO:0009056 351 0.056
regulation of protein metabolic process GO:0051246 289 0.054
organophosphate metabolic process GO:0019637 370 0.054
rna biosynthetic process GO:0032774 380 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.051
negative regulation of transcription dna templated GO:0045892 116 0.051
regulation of transcription dna templated GO:0006355 374 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
response to peptide GO:1901652 292 0.045
regulation of catalytic activity GO:0050790 304 0.045
organic substance catabolic process GO:1901575 316 0.045
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.045
intracellular signal transduction GO:0035556 314 0.044
regulation of cell proliferation GO:0042127 359 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.043
regulation of cellular ketone metabolic process GO:0010565 27 0.043
apoptotic process GO:0006915 381 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
protein phosphorylation GO:0006468 345 0.040
programmed cell death GO:0012501 392 0.039
single organism biosynthetic process GO:0044711 342 0.039
central nervous system development GO:0007417 311 0.038
regulation of rna metabolic process GO:0051252 391 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.037
positive regulation of response to stimulus GO:0048584 285 0.036
transmembrane transport GO:0055085 412 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.036
cellular response to stress GO:0033554 269 0.035
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
positive regulation of rna metabolic process GO:0051254 203 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
cellular amine metabolic process GO:0044106 38 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
response to extracellular stimulus GO:0009991 380 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
positive regulation of signaling GO:0023056 270 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.033
immune system process GO:0002376 204 0.033
regulation of cellular component organization GO:0051128 368 0.032
Rat
positive regulation of protein metabolic process GO:0051247 178 0.032
response to nutrient levels GO:0031667 370 0.032
positive regulation of molecular function GO:0044093 230 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.031
regulation of signal transduction GO:0009966 318 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.030
defense response GO:0006952 194 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
regulation of programmed cell death GO:0043067 341 0.029
negative regulation of phosphorus metabolic process GO:0010563 80 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
peptidyl amino acid modification GO:0018193 126 0.028
nucleotide metabolic process GO:0009117 279 0.027
positive regulation of cell communication GO:0010647 271 0.027
neuron differentiation GO:0030182 368 0.027
organelle organization GO:0006996 266 0.027
Rat
regulation of cell differentiation GO:0045595 320 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
head development GO:0060322 247 0.026
lipid metabolic process GO:0006629 283 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
Rat
regulation of phosphate metabolic process GO:0019220 349 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
negative regulation of gene expression GO:0010629 199 0.026
response to inorganic substance GO:0010035 377 0.026
single organism intracellular transport GO:1902582 166 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
protein complex subunit organization GO:0071822 302 0.025
Rat
regulation of apoptotic process GO:0042981 335 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
protein localization GO:0008104 191 0.025
homeostatic process GO:0042592 331 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
negative regulation of rna metabolic process GO:0051253 123 0.023
macromolecule localization GO:0033036 252 0.023
reproductive process GO:0022414 372 0.023
macromolecular complex assembly GO:0065003 273 0.023
Rat
response to external biotic stimulus GO:0043207 221 0.022
regulation of kinase activity GO:0043549 117 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
secretion GO:0046903 307 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
response to biotic stimulus GO:0009607 226 0.022
negative regulation of molecular function GO:0044092 133 0.022
response to nutrient GO:0007584 248 0.022
multi organism reproductive process GO:0044703 262 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
single organism organelle organization GO:1902589 180 0.022
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
regulation of protein modification process GO:0031399 194 0.022
cellular component assembly GO:0022607 360 0.022
Rat
cellular response to lipid GO:0071396 201 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
response to other organism GO:0051707 220 0.021
single organism catabolic process GO:0044712 283 0.021
negative regulation of developmental process GO:0051093 125 0.021
response to glucocorticoid GO:0051384 223 0.021
response to lipopolysaccharide GO:0032496 191 0.021
positive regulation of transcription dna templated GO:0045893 197 0.020
response to wounding GO:0009611 254 0.020
cellular catabolic process GO:0044248 295 0.020
anion transport GO:0006820 178 0.020
cellular response to peptide GO:1901653 133 0.020
mapk cascade GO:0000165 140 0.020
positive regulation of gene expression GO:0010628 244 0.020
establishment of protein localization GO:0045184 141 0.020
histone h3 acetylation GO:0043966 2 0.020
dephosphorylation GO:0016311 98 0.020
nucleoside metabolic process GO:0009116 179 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
response to estrogen GO:0043627 232 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
tissue development GO:0009888 252 0.019
response to peptide hormone GO:0043434 278 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
peptidyl tyrosine modification GO:0018212 72 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
regulation of catabolic process GO:0009894 113 0.019
chemical homeostasis GO:0048878 292 0.018
regulation of phosphorylation GO:0042325 248 0.018
cellular response to cytokine stimulus GO:0071345 127 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
ion transmembrane transport GO:0034220 365 0.018
neuron projection development GO:0031175 273 0.018
carbohydrate metabolic process GO:0005975 130 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
cellular component biogenesis GO:0044085 368 0.018
Rat
cellular response to organonitrogen compound GO:0071417 197 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
oxidation reduction process GO:0055114 304 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
brain development GO:0007420 247 0.018
establishment of tissue polarity GO:0007164 2 0.017
purine containing compound metabolic process GO:0072521 253 0.017
protein complex assembly GO:0006461 263 0.017
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.017
negative regulation of immune system process GO:0002683 39 0.017
multicellular organism growth GO:0035264 1 0.017
positive regulation of signal transduction GO:0009967 175 0.017
small molecule biosynthetic process GO:0044283 124 0.017
regulation of hydrolase activity GO:0051336 143 0.016
single organism reproductive process GO:0044702 297 0.016
dna metabolic process GO:0006259 96 0.016
nitrogen compound transport GO:0071705 229 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
negative regulation of cell death GO:0060548 229 0.016
response to decreased oxygen levels GO:0036293 237 0.016
regulation of transferase activity GO:0051338 123 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
axis specification GO:0009798 4 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
positive regulation of developmental process GO:0051094 283 0.016
regulation of protein kinase activity GO:0045859 105 0.016
response to oxygen levels GO:0070482 265 0.016
neuron development GO:0048666 286 0.016
mesoderm development GO:0007498 2 0.016
b cell differentiation GO:0030183 2 0.016
positive regulation of cell differentiation GO:0045597 217 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
cofactor metabolic process GO:0051186 95 0.015
regulation of neurogenesis GO:0050767 247 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
response to corticosteroid GO:0031960 235 0.015
regulation of secretion by cell GO:1903530 208 0.015
regulation of body fluid levels GO:0050878 90 0.015
protein complex biogenesis GO:0070271 263 0.015
Rat
neuron death GO:0070997 127 0.015
intracellular transport GO:0046907 185 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
cell projection organization GO:0030030 302 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
response to ionizing radiation GO:0010212 59 0.014
regulation of nervous system development GO:0051960 264 0.014
branched chain amino acid transport GO:0015803 2 0.014
ras protein signal transduction GO:0007265 29 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
response to purine containing compound GO:0014074 126 0.014
gastrulation GO:0007369 2 0.014
proteolysis GO:0006508 175 0.014
positive regulation of protein modification process GO:0031401 142 0.014
growth GO:0040007 165 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
organic anion transport GO:0015711 132 0.014
metal ion transport GO:0030001 289 0.014
Rat
regulation of immune system process GO:0002682 123 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
jak stat cascade GO:0007259 26 0.014
response to ethanol GO:0045471 162 0.014
multi multicellular organism process GO:0044706 138 0.014
regulation of activation of janus kinase activity GO:0010533 1 0.014
regulation of cell development GO:0060284 263 0.014
regulation of hormone levels GO:0010817 187 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
protein transport GO:0015031 132 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
organic acid transport GO:0015849 116 0.013
aging GO:0007568 241 0.013
response to radiation GO:0009314 137 0.013
heterocycle catabolic process GO:0046700 167 0.013
protein oligomerization GO:0051259 191 0.013
synaptic transmission GO:0007268 235 0.013
positive regulation of cell death GO:0010942 184 0.013
positive regulation of cell development GO:0010720 176 0.013
response to bacterium GO:0009617 200 0.013
single organism cellular localization GO:1902580 102 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
regulation of synaptic transmission GO:0050804 141 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of signaling GO:0023057 157 0.013
regulation of neuron differentiation GO:0045664 208 0.013
carboxylic acid transport GO:0046942 115 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
gland development GO:0048732 155 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
cation transmembrane transport GO:0098655 263 0.012
endocrine system development GO:0035270 30 0.012
cell cell signaling GO:0007267 335 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
positive regulation of transport GO:0051050 245 0.012
response to metal ion GO:0010038 253 0.012
response to glucose GO:0009749 136 0.012
response to organophosphorus GO:0046683 102 0.012
anterior posterior pattern specification GO:0009952 1 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
response to acid chemical GO:0001101 222 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
cellular component movement GO:0006928 248 0.012
regulation of growth GO:0040008 105 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
lipid biosynthetic process GO:0008610 128 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
amino acid transport GO:0006865 70 0.012
cation transport GO:0006812 382 0.012
Rat
locomotion GO:0040011 237 0.012
embryonic pattern specification GO:0009880 1 0.012
cell type specific apoptotic process GO:0097285 134 0.012
negative regulation of phosphorylation GO:0042326 57 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
cytokine production involved in inflammatory response GO:0002534 1 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
response to carbohydrate GO:0009743 183 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
cellular protein localization GO:0034613 122 0.011
negative regulation of collagen biosynthetic process GO:0032966 4 0.011
response to cytokine GO:0034097 215 0.011
ion homeostasis GO:0050801 212 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
negative regulation of skeletal muscle tissue development GO:0048642 3 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
organophosphate catabolic process GO:0046434 148 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
response to hypoxia GO:0001666 231 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
aromatic compound catabolic process GO:0019439 168 0.011
hormone metabolic process GO:0042445 69 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
response to oxidative stress GO:0006979 186 0.011
organic acid biosynthetic process GO:0016053 83 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
regulation of homeostatic process GO:0032844 101 0.011
glucose homeostasis GO:0042593 75 0.011
positive regulation of transferase activity GO:0051347 81 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
lens fiber cell differentiation GO:0070306 3 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
regulation of system process GO:0044057 208 0.010
skeletal muscle tissue development GO:0007519 31 0.010
circadian rhythm GO:0007623 88 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
female pregnancy GO:0007565 122 0.010
regulation of cellular localization GO:0060341 263 0.010
lipid storage GO:0019915 1 0.010

Fkbp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.011
cancer DOID:162 0 0.011