Rattus norvegicus

0 known processes

Pdhx

pyruvate dehydrogenase complex, component X

(Aliases: Ac1164)

Pdhx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.223
coenzyme metabolic process GO:0006732 86 0.209
cofactor biosynthetic process GO:0051188 28 0.207
carboxylic acid metabolic process GO:0019752 289 0.180
coenzyme biosynthetic process GO:0009108 22 0.167
catabolic process GO:0009056 351 0.116
acetyl coa metabolic process GO:0006084 17 0.109
organic acid metabolic process GO:0006082 292 0.106
nucleotide metabolic process GO:0009117 279 0.104
sulfur compound biosynthetic process GO:0044272 19 0.099
oxoacid metabolic process GO:0043436 290 0.095
organophosphate metabolic process GO:0019637 370 0.089
response to extracellular stimulus GO:0009991 380 0.089
regulation of catalytic activity GO:0050790 304 0.079
regulation of protein metabolic process GO:0051246 289 0.079
cellular ketone metabolic process GO:0042180 51 0.079
negative regulation of cellular metabolic process GO:0031324 281 0.076
single organism biosynthetic process GO:0044711 342 0.073
regulation of nucleic acid templated transcription GO:1903506 380 0.073
regulation of cellular protein metabolic process GO:0032268 267 0.073
immune system process GO:0002376 204 0.070
negative regulation of metabolic process GO:0009892 331 0.064
response to inorganic substance GO:0010035 377 0.063
response to nutrient levels GO:0031667 370 0.063
purine nucleoside monophosphate metabolic process GO:0009126 84 0.057
macromolecular complex subunit organization GO:0043933 339 0.057
establishment of protein localization GO:0045184 141 0.056
regulation of phosphate metabolic process GO:0019220 349 0.055
regulation of molecular function GO:0065009 398 0.055
oxidation reduction process GO:0055114 304 0.054
nucleoside phosphate metabolic process GO:0006753 283 0.053
regulation of programmed cell death GO:0043067 341 0.053
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
regulation of rna metabolic process GO:0051252 391 0.051
pyruvate metabolic process GO:0006090 27 0.050
cofactor metabolic process GO:0051186 95 0.049
single organism organelle organization GO:1902589 180 0.049
rna biosynthetic process GO:0032774 380 0.048
proteolysis GO:0006508 175 0.048
negative regulation of phosphorus metabolic process GO:0010563 80 0.048
negative regulation of cellular protein metabolic process GO:0032269 106 0.047
apoptotic process GO:0006915 381 0.046
regulation of cell proliferation GO:0042127 359 0.045
regulation of kinase activity GO:0043549 117 0.044
macromolecule localization GO:0033036 252 0.044
atp metabolic process GO:0046034 72 0.043
secretion GO:0046903 307 0.042
nucleoside triphosphate metabolic process GO:0009141 144 0.042
positive regulation of protein metabolic process GO:0051247 178 0.042
secretion by cell GO:0032940 248 0.041
cellular response to stress GO:0033554 269 0.040
protein localization GO:0008104 191 0.040
positive regulation of molecular function GO:0044093 230 0.040
organelle organization GO:0006996 266 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
acetyl coa biosynthetic process GO:0006085 6 0.038
intracellular signal transduction GO:0035556 314 0.038
negative regulation of multicellular organismal process GO:0051241 203 0.038
single organism catabolic process GO:0044712 283 0.038
response to oxygen levels GO:0070482 265 0.037
cellular homeostasis GO:0019725 252 0.037
regulation of hydrolase activity GO:0051336 143 0.036
transcription dna templated GO:0006351 377 0.036
negative regulation of phosphate metabolic process GO:0045936 80 0.036
protein transport GO:0015031 132 0.036
regulation of cell differentiation GO:0045595 320 0.035
purine nucleoside triphosphate metabolic process GO:0009144 141 0.035
transmembrane transport GO:0055085 412 0.035
ribonucleoside metabolic process GO:0009119 174 0.035
regulation of apoptotic process GO:0042981 335 0.034
programmed cell death GO:0012501 392 0.034
homeostatic process GO:0042592 331 0.034
regulation of transcription dna templated GO:0006355 374 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
reactive oxygen species metabolic process GO:0072593 37 0.033
cellular component morphogenesis GO:0032989 155 0.033
response to starvation GO:0042594 59 0.033
organonitrogen compound catabolic process GO:1901565 179 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
response to decreased oxygen levels GO:0036293 237 0.033
dicarboxylic acid metabolic process GO:0043648 42 0.033
ribonucleoside triphosphate metabolic process GO:0009199 141 0.032
positive regulation of cell communication GO:0010647 271 0.032
negative regulation of response to stimulus GO:0048585 155 0.031
signal release GO:0023061 145 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
negative regulation of protein metabolic process GO:0051248 114 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
regulation of transferase activity GO:0051338 123 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
amine metabolic process GO:0009308 38 0.029
response to bacterium GO:0009617 200 0.029
negative regulation of gene expression GO:0010629 199 0.029
organic substance catabolic process GO:1901575 316 0.029
rna metabolic process GO:0016070 406 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
vesicle mediated transport GO:0016192 181 0.028
ribonucleoside monophosphate metabolic process GO:0009161 88 0.028
response to metal ion GO:0010038 253 0.028
response to oxidative stress GO:0006979 186 0.027
glycosyl compound metabolic process GO:1901657 182 0.027
ion transmembrane transport GO:0034220 365 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
single organism cellular localization GO:1902580 102 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
response to external biotic stimulus GO:0043207 221 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
multi organism reproductive process GO:0044703 262 0.027
protein targeting GO:0006605 61 0.027
single organism reproductive process GO:0044702 297 0.027
cellular catabolic process GO:0044248 295 0.027
regulation of nervous system development GO:0051960 264 0.026
cellular amine metabolic process GO:0044106 38 0.026
reproductive process GO:0022414 372 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
cytoskeleton organization GO:0007010 111 0.026
negative regulation of nervous system development GO:0051961 79 0.026
neuron apoptotic process GO:0051402 88 0.025
cellular protein localization GO:0034613 122 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
response to nutrient GO:0007584 248 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
multicellular organism reproduction GO:0032504 233 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
nucleic acid templated transcription GO:0097659 379 0.024
regulation of catabolic process GO:0009894 113 0.024
protein complex subunit organization GO:0071822 302 0.024
negative regulation of cell communication GO:0010648 158 0.024
cellular response to external stimulus GO:0071496 118 0.024
regulation of neurogenesis GO:0050767 247 0.024
centrosome organization GO:0051297 1 0.023
aging GO:0007568 241 0.023
regulation of cellular localization GO:0060341 263 0.023
regulation of cellular component organization GO:0051128 368 0.023
neuron death GO:0070997 127 0.023
ras protein signal transduction GO:0007265 29 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
female pregnancy GO:0007565 122 0.023
nucleoside monophosphate metabolic process GO:0009123 93 0.023
response to reactive oxygen species GO:0000302 120 0.022
positive regulation of developmental process GO:0051094 283 0.022
thioester metabolic process GO:0035383 28 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
cellular response to oxidative stress GO:0034599 76 0.022
oxidoreduction coenzyme metabolic process GO:0006733 31 0.022
regulation of phosphorylation GO:0042325 248 0.022
protein complex biogenesis GO:0070271 263 0.022
protein processing GO:0016485 68 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.021
protein phosphorylation GO:0006468 345 0.021
negative regulation of neurogenesis GO:0050768 78 0.021
response to ethanol GO:0045471 162 0.021
dna metabolic process GO:0006259 96 0.021
intracellular protein transport GO:0006886 79 0.021
anatomical structure morphogenesis GO:0009653 298 0.020
response to hypoxia GO:0001666 231 0.020
positive regulation of signaling GO:0023056 270 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
regulation of growth GO:0040008 105 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
hormone transport GO:0009914 121 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of cell proliferation GO:0008284 249 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
cellular component assembly GO:0022607 360 0.019
cell type specific apoptotic process GO:0097285 134 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
negative regulation of molecular function GO:0044092 133 0.019
regulation of neuron apoptotic process GO:0043523 83 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
response to acid chemical GO:0001101 222 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
acyl coa metabolic process GO:0006637 28 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
multi multicellular organism process GO:0044706 138 0.018
intracellular transport GO:0046907 185 0.018
defense response GO:0006952 194 0.018
negative regulation of signaling GO:0023057 157 0.018
regulation of cell development GO:0060284 263 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
thioester biosynthetic process GO:0035384 7 0.018
developmental process involved in reproduction GO:0003006 159 0.018
cellular macromolecule localization GO:0070727 122 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
negative regulation of cell death GO:0060548 229 0.018
negative regulation of phosphorylation GO:0042326 57 0.017
regulation of protein modification process GO:0031399 194 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
endocytosis GO:0006897 84 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of immune system process GO:0002682 123 0.017
negative regulation of signal transduction GO:0009968 83 0.017
central nervous system development GO:0007417 311 0.017
acyl coa biosynthetic process GO:0071616 7 0.017
protein maturation GO:0051604 68 0.017
regulation of neuron death GO:1901214 115 0.016
negative regulation of neuron death GO:1901215 69 0.016
chemical homeostasis GO:0048878 292 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
single organism intracellular transport GO:1902582 166 0.016
regulation of signal transduction GO:0009966 318 0.016
cytoplasmic transport GO:0016482 115 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
cell part morphogenesis GO:0032990 123 0.016
mapk cascade GO:0000165 140 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
mitotic spindle organization GO:0007052 2 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
spindle organization GO:0007051 2 0.016
regulation of secretion by cell GO:1903530 208 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
response to cytokine GO:0034097 215 0.016
positive regulation of nervous system development GO:0051962 178 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regulation of membrane potential GO:0042391 110 0.015
regulation of organelle organization GO:0033043 80 0.015
localization of cell GO:0051674 202 0.015
establishment of protein localization to organelle GO:0072594 44 0.015
regulation of response to external stimulus GO:0032101 106 0.015
response to alkaloid GO:0043279 132 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
pyridine containing compound metabolic process GO:0072524 32 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
regulation of mapk cascade GO:0043408 116 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
cell cycle GO:0007049 101 0.015
positive regulation of secretion GO:0051047 140 0.015
regulation of peptidase activity GO:0052547 55 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
negative regulation of neuron apoptotic process GO:0043524 45 0.014
negative regulation of developmental process GO:0051093 125 0.014
regulation of neuron projection development GO:0010975 161 0.014
response to lipopolysaccharide GO:0032496 191 0.014
mitochondrion organization GO:0007005 35 0.014
peptidyl amino acid modification GO:0018193 126 0.014
cell fate determination GO:0001709 2 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
cellular component biogenesis GO:0044085 368 0.014
cellular response to oxygen levels GO:0071453 60 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
negative regulation of transport GO:0051051 136 0.014
neuron differentiation GO:0030182 368 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of synaptic transmission GO:0050804 141 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
positive regulation of gene expression GO:0010628 244 0.013
behavior GO:0007610 205 0.013
cellular response to lipid GO:0071396 201 0.013
centrosome cycle GO:0007098 1 0.013
regulation of protein maturation GO:1903317 50 0.013
brain development GO:0007420 247 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
cell motility GO:0048870 202 0.013
cell cell signaling GO:0007267 335 0.013
negative regulation of cell development GO:0010721 82 0.013
negative regulation of innate immune response GO:0045824 4 0.013
positive regulation of transport GO:0051050 245 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
protein localization to organelle GO:0033365 57 0.013
transmission of nerve impulse GO:0019226 42 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
response to insulin GO:0032868 133 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
reproduction GO:0000003 245 0.012
membrane organization GO:0061024 94 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
immune response GO:0006955 104 0.012
negative regulation of protein maturation GO:1903318 47 0.012
nucleoside metabolic process GO:0009116 179 0.012
atp synthesis coupled electron transport GO:0042773 2 0.012
regulation of dendrite development GO:0050773 59 0.012
aromatic compound catabolic process GO:0019439 168 0.012
cell morphogenesis GO:0000902 142 0.012
regulation of peptide secretion GO:0002791 82 0.012
cellular respiration GO:0045333 21 0.012
neuron projection development GO:0031175 273 0.012
behavioral response to ethanol GO:0048149 1 0.012
nitrogen compound transport GO:0071705 229 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
macromolecular complex assembly GO:0065003 273 0.012
hemopoiesis GO:0030097 34 0.012
anterior posterior pattern specification GO:0009952 1 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
nucleotide catabolic process GO:0009166 139 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of endopeptidase activity GO:0052548 51 0.012
macromolecule catabolic process GO:0009057 58 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
posttranscriptional regulation of gene expression GO:0010608 37 0.012
regulation of stem cell differentiation GO:2000736 2 0.011
dephosphorylation GO:0016311 98 0.011
cellular response to peptide GO:1901653 133 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
regulation of peptide transport GO:0090087 87 0.011
regulation of anatomical structure size GO:0090066 135 0.011
dendrite development GO:0016358 72 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
head development GO:0060322 247 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
organophosphate catabolic process GO:0046434 148 0.011
protein import GO:0017038 37 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
single organism membrane organization GO:0044802 74 0.011
cellular component movement GO:0006928 248 0.011
cell adhesion GO:0007155 110 0.011
metal ion transport GO:0030001 289 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
cardiac ventricle development GO:0003231 1 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
single organism behavior GO:0044708 130 0.011
regulation of neuron differentiation GO:0045664 208 0.011
multicellular organismal signaling GO:0035637 44 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
action potential GO:0001508 54 0.011
positive regulation of mitochondrion organization GO:0010822 4 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
sulfur compound metabolic process GO:0006790 70 0.010
carbohydrate homeostasis GO:0033500 75 0.010
regulation of proteolysis GO:0030162 66 0.010
amide transport GO:0042886 105 0.010
branched chain amino acid catabolic process GO:0009083 4 0.010
actin filament based process GO:0030029 86 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
peptide biosynthetic process GO:0043043 3 0.010
synaptic transmission GO:0007268 235 0.010
regulation of protein processing GO:0070613 50 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
hematopoietic or lymphoid organ development GO:0048534 36 0.010
chromosome segregation GO:0007059 2 0.010
cellular component maintenance GO:0043954 4 0.010

Pdhx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.022
sensory system disease DOID:0050155 0 0.022
disease of anatomical entity DOID:7 0 0.022
eye and adnexa disease DOID:1492 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022
disease of metabolism DOID:0014667 0 0.015
amino acid metabolic disorder DOID:9252 0 0.013
inherited metabolic disorder DOID:655 0 0.013
organic acidemia DOID:0060159 0 0.013
musculoskeletal system disease DOID:17 0 0.013