Rattus norvegicus

33 known processes

Pdhb

pyruvate dehydrogenase (lipoamide) beta

(Aliases: MGC94149)

Pdhb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.747
atp synthesis coupled electron transport GO:0042773 2 0.714
sulfur compound biosynthetic process GO:0044272 19 0.638
oxidative phosphorylation GO:0006119 4 0.570
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.437
glycosyl compound metabolic process GO:1901657 182 0.353
hydrogen peroxide metabolic process GO:0042743 13 0.330
electron transport chain GO:0022900 5 0.316
single organism biosynthetic process GO:0044711 342 0.288
oxidation reduction process GO:0055114 304 0.267
organic acid metabolic process GO:0006082 292 0.256
acyl coa biosynthetic process GO:0071616 7 0.219
cofactor biosynthetic process GO:0051188 28 0.213
ribonucleoside triphosphate metabolic process GO:0009199 141 0.200
pyruvate metabolic process GO:0006090 27 0.189
atp metabolic process GO:0046034 72 0.187
thioester metabolic process GO:0035383 28 0.187
nucleoside monophosphate metabolic process GO:0009123 93 0.184
organophosphate metabolic process GO:0019637 370 0.181
energy derivation by oxidation of organic compounds GO:0015980 46 0.176
mitochondrial atp synthesis coupled electron transport GO:0042775 2 0.176
generation of precursor metabolites and energy GO:0006091 62 0.146
purine nucleoside triphosphate metabolic process GO:0009144 141 0.124
ribonucleoside metabolic process GO:0009119 174 0.123
purine ribonucleotide metabolic process GO:0009150 227 0.123
dicarboxylic acid metabolic process GO:0043648 42 0.118
purine nucleotide metabolic process GO:0006163 229 0.116
purine containing compound metabolic process GO:0072521 253 0.116
cellular glucan metabolic process GO:0006073 23 0.113
carboxylic acid metabolic process GO:0019752 289 0.113
nucleoside phosphate metabolic process GO:0006753 283 0.106
nucleobase containing small molecule metabolic process GO:0055086 316 0.099
nucleotide metabolic process GO:0009117 279 0.097
carbohydrate derivative metabolic process GO:1901135 346 0.096
ribonucleoside monophosphate metabolic process GO:0009161 88 0.087
purine nucleoside metabolic process GO:0042278 169 0.087
coenzyme biosynthetic process GO:0009108 22 0.080
oxoacid metabolic process GO:0043436 290 0.077
nucleoside triphosphate metabolic process GO:0009141 144 0.077
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.068
ribonucleotide metabolic process GO:0009259 231 0.068
purine ribonucleoside metabolic process GO:0046128 168 0.063
coenzyme metabolic process GO:0006732 86 0.063
purine nucleoside monophosphate metabolic process GO:0009126 84 0.056
acyl coa metabolic process GO:0006637 28 0.055
dephosphorylation GO:0016311 98 0.055
ribose phosphate metabolic process GO:0019693 235 0.048
cellular respiration GO:0045333 21 0.047
glycogen metabolic process GO:0005977 23 0.045
aerobic respiration GO:0009060 13 0.044
single organism catabolic process GO:0044712 283 0.041
polysaccharide metabolic process GO:0005976 25 0.041
nucleoside metabolic process GO:0009116 179 0.041
regulation of proteasomal protein catabolic process GO:0061136 4 0.039
response to nutrient GO:0007584 248 0.037
sulfur compound metabolic process GO:0006790 70 0.034
negative regulation of hydrogen peroxide biosynthetic process GO:0010730 2 0.033
malate metabolic process GO:0006108 5 0.032
response to nutrient levels GO:0031667 370 0.032
ion transmembrane transport GO:0034220 365 0.031
oxidoreduction coenzyme metabolic process GO:0006733 31 0.029
response to oxidative stress GO:0006979 186 0.027
catabolic process GO:0009056 351 0.027
regulation of apoptotic process GO:0042981 335 0.026
regulation of catabolic process GO:0009894 113 0.026
apoptotic process GO:0006915 381 0.025
response to extracellular stimulus GO:0009991 380 0.025
transmembrane transport GO:0055085 412 0.024
nitrogen compound transport GO:0071705 229 0.024
programmed cell death GO:0012501 392 0.023
reactive oxygen species metabolic process GO:0072593 37 0.022
cellular catabolic process GO:0044248 295 0.022
negative regulation of metabolic process GO:0009892 331 0.022
cellular ketone metabolic process GO:0042180 51 0.022
regulation of transcription dna templated GO:0006355 374 0.021
organic substance catabolic process GO:1901575 316 0.021
chemosensory behavior GO:0007635 2 0.021
aromatic compound catabolic process GO:0019439 168 0.021
tricarboxylic acid cycle GO:0006099 11 0.021
regulation of cell proliferation GO:0042127 359 0.021
sleep GO:0030431 30 0.020
regulation of programmed cell death GO:0043067 341 0.020
purine nucleoside biosynthetic process GO:0042451 21 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.018
regulation of peptide transport GO:0090087 87 0.018
regulation of protein metabolic process GO:0051246 289 0.018
protein complex subunit organization GO:0071822 302 0.018
Fly
cellular amine metabolic process GO:0044106 38 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
regulation of molecular function GO:0065009 398 0.017
lipid biosynthetic process GO:0008610 128 0.017
spindle organization GO:0007051 2 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
intracellular transport GO:0046907 185 0.017
energy reserve metabolic process GO:0006112 25 0.016
meiotic cell cycle process GO:1903046 3 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
negative regulation of hydrogen peroxide metabolic process GO:0010727 2 0.016
negative regulation of chromosome organization GO:2001251 1 0.016
response to external biotic stimulus GO:0043207 221 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
protein localization to chromosome centromeric region GO:0071459 1 0.015
cellular polysaccharide metabolic process GO:0044264 23 0.015
organelle organization GO:0006996 266 0.015
Fly
regulation of catalytic activity GO:0050790 304 0.015
regulation of hydrogen peroxide metabolic process GO:0010310 3 0.014
anion transport GO:0006820 178 0.014
multi organism reproductive process GO:0044703 262 0.014
sexual reproduction GO:0019953 148 0.014
neuron development GO:0048666 286 0.014
protein localization GO:0008104 191 0.014
lipid storage GO:0019915 1 0.014
progesterone biosynthetic process GO:0006701 3 0.014
regulation of apoptotic signaling pathway GO:2001233 13 0.014
response to other organism GO:0051707 220 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of peptide secretion GO:0002791 82 0.013
ras protein signal transduction GO:0007265 29 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
central nervous system development GO:0007417 311 0.013
negative regulation of gene expression GO:0010629 199 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
postsynaptic density protein 95 clustering GO:0097119 2 0.013
cell projection morphogenesis GO:0048858 123 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
macroautophagy GO:0016236 4 0.013
negative regulation of protein modification by small protein conjugation or removal GO:1903321 4 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
epithelium development GO:0060429 96 0.012
proteolysis GO:0006508 175 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
anterior posterior pattern specification GO:0009952 1 0.012
pyridine containing compound metabolic process GO:0072524 32 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
amine metabolic process GO:0009308 38 0.012
response to activity GO:0014823 73 0.012
positive regulation of peptide hormone secretion GO:0090277 50 0.012
metaphase anaphase transition of cell cycle GO:0044784 1 0.012
peptide hormone secretion GO:0030072 84 0.012
single organism reproductive process GO:0044702 297 0.012
cell redox homeostasis GO:0045454 1 0.011
mitotic spindle organization GO:0007052 2 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cellular macromolecule localization GO:0070727 122 0.011
maintenance of location GO:0051235 17 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
multicellular organism reproduction GO:0032504 233 0.011
macromolecule localization GO:0033036 252 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
negative regulation of protein maturation GO:1903318 47 0.011
positive regulation of transport GO:0051050 245 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.010
cilium morphogenesis GO:0060271 2 0.010
regulation of cellular component organization GO:0051128 368 0.010
brain development GO:0007420 247 0.010
regulation of cellular localization GO:0060341 263 0.010
neuron projection morphogenesis GO:0048812 122 0.010
homeostatic process GO:0042592 331 0.010
purine nucleobase metabolic process GO:0006144 4 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.010
pyridine nucleotide metabolic process GO:0019362 28 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
anion transmembrane transport GO:0098656 77 0.010
developmental process involved in reproduction GO:0003006 159 0.010
chromatin organization GO:0006325 34 0.010
regulation of gluconeogenesis GO:0006111 4 0.010

Pdhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.015
sensory system disease DOID:0050155 0 0.015
disease of anatomical entity DOID:7 0 0.015
eye and adnexa disease DOID:1492 0 0.015
nervous system disease DOID:863 0 0.015
eye disease DOID:5614 0 0.015
disease of metabolism DOID:0014667 0 0.015
amino acid metabolic disorder DOID:9252 0 0.015
inherited metabolic disorder DOID:655 0 0.015
organic acidemia DOID:0060159 0 0.015