Rattus norvegicus

29 known processes

Uchl1

ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Uchl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.113
carboxylic acid metabolic process GO:0019752 289 0.100
organic substance catabolic process GO:1901575 316 0.099
organic acid metabolic process GO:0006082 292 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.076
catabolic process GO:0009056 351 0.074
cell projection organization GO:0030030 302 0.066
response to nutrient levels GO:0031667 370 0.065
cellular amino acid metabolic process GO:0006520 107 0.063
organelle organization GO:0006996 266 0.063
single organism catabolic process GO:0044712 283 0.063
regulation of cell development GO:0060284 263 0.060
brain development GO:0007420 247 0.059
regulation of neuron differentiation GO:0045664 208 0.059
axonogenesis GO:0007409 71 0.057
rna metabolic process GO:0016070 406 0.056
regulation of cell proliferation GO:0042127 359 0.055
regulation of multicellular organismal development GO:2000026 376 0.054
regulation of cellular component organization GO:0051128 368 0.053
regulation of apoptotic process GO:0042981 335 0.052
neuron projection development GO:0031175 273 0.051
regulation of neuron projection development GO:0010975 161 0.051
regulation of programmed cell death GO:0043067 341 0.050
neuron projection morphogenesis GO:0048812 122 0.050
response to estrogen GO:0043627 232 0.049
positive regulation of response to stimulus GO:0048584 285 0.048
neuron differentiation GO:0030182 368 0.047
regulation of molecular function GO:0065009 398 0.047
Human
regulation of cell differentiation GO:0045595 320 0.047
positive regulation of cell differentiation GO:0045597 217 0.046
response to peptide hormone GO:0043434 278 0.045
protein complex biogenesis GO:0070271 263 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.044
positive regulation of cellular component organization GO:0051130 200 0.043
protein complex subunit organization GO:0071822 302 0.043
regulation of anatomical structure size GO:0090066 135 0.042
response to axon injury GO:0048678 59 0.042
central nervous system development GO:0007417 311 0.042
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
intracellular transport GO:0046907 185 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.041
Human
regulation of rna metabolic process GO:0051252 391 0.040
regulation of cell projection organization GO:0031344 175 0.040
head development GO:0060322 247 0.040
regulation of rna biosynthetic process GO:2001141 381 0.039
response to inorganic substance GO:0010035 377 0.039
neuron death GO:0070997 127 0.039
response to radiation GO:0009314 137 0.039
single organism organelle organization GO:1902589 180 0.038
cellular component assembly GO:0022607 360 0.038
transcription dna templated GO:0006351 377 0.037
cellular response to stress GO:0033554 269 0.037
positive regulation of cell communication GO:0010647 271 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
neuron development GO:0048666 286 0.037
positive regulation of neuron projection development GO:0010976 99 0.037
regulation of neurogenesis GO:0050767 247 0.037
regulation of transcription dna templated GO:0006355 374 0.037
macromolecular complex assembly GO:0065003 273 0.036
response to peptide GO:1901652 292 0.036
reproductive process GO:0022414 372 0.036
response to extracellular stimulus GO:0009991 380 0.036
regulation of organelle organization GO:0033043 80 0.036
negative regulation of metabolic process GO:0009892 331 0.035
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.035
regulation of signal transduction GO:0009966 318 0.035
Human
positive regulation of nervous system development GO:0051962 178 0.035
axon development GO:0061564 96 0.035
regulation of neuron death GO:1901214 115 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.034
Human
cellular response to endogenous stimulus GO:0071495 377 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
neuron apoptotic process GO:0051402 88 0.033
programmed cell death GO:0012501 392 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
regulation of nervous system development GO:0051960 264 0.032
eye morphogenesis GO:0048592 4 0.032
cellular ketone metabolic process GO:0042180 51 0.032
cellular catabolic process GO:0044248 295 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
rna biosynthetic process GO:0032774 380 0.031
response to growth factor GO:0070848 189 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
positive regulation of neurogenesis GO:0050769 165 0.030
regulation of catalytic activity GO:0050790 304 0.030
Human
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of cell projection organization GO:0031346 111 0.029
positive regulation of cell death GO:0010942 184 0.029
developmental growth GO:0048589 100 0.029
response to metal ion GO:0010038 253 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
negative regulation of protein metabolic process GO:0051248 114 0.029
Human
nucleic acid templated transcription GO:0097659 379 0.029
regulation of cellular catabolic process GO:0031329 101 0.028
aromatic compound catabolic process GO:0019439 168 0.028
response to wounding GO:0009611 254 0.028
organic acid biosynthetic process GO:0016053 83 0.028
secretion GO:0046903 307 0.028
single organism reproductive process GO:0044702 297 0.028
cellular amine metabolic process GO:0044106 38 0.027
cell part morphogenesis GO:0032990 123 0.027
negative regulation of cell death GO:0060548 229 0.027
cell morphogenesis involved in differentiation GO:0000904 119 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
small molecule biosynthetic process GO:0044283 124 0.027
macromolecule localization GO:0033036 252 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
Human
apoptotic process GO:0006915 381 0.026
synaptic growth at neuromuscular junction GO:0051124 1 0.026
multi organism reproductive process GO:0044703 262 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
Human
cellular response to oxygen containing compound GO:1901701 386 0.026
positive regulation of transport GO:0051050 245 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
immune system process GO:0002376 204 0.026
regulation of protein phosphorylation GO:0001932 183 0.025
Human
response to toxic substance GO:0009636 133 0.025
positive regulation of neuron differentiation GO:0045666 126 0.025
protein transport GO:0015031 132 0.025
regulation of protein metabolic process GO:0051246 289 0.025
Human
response to decreased oxygen levels GO:0036293 237 0.025
amine metabolic process GO:0009308 38 0.025
multicellular organism reproduction GO:0032504 233 0.024
response to nutrient GO:0007584 248 0.024
regeneration GO:0031099 163 0.024
protein phosphorylation GO:0006468 345 0.024
Human
response to oxygen levels GO:0070482 265 0.024
positive regulation of protein metabolic process GO:0051247 178 0.023
cellular component biogenesis GO:0044085 368 0.023
cation transport GO:0006812 382 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
carboxylic acid biosynthetic process GO:0046394 83 0.023
axon cargo transport GO:0008088 1 0.023
regulation of cell motility GO:2000145 131 0.023
regulation of catabolic process GO:0009894 113 0.023
reactive oxygen species metabolic process GO:0072593 37 0.022
regulation of hydrolase activity GO:0051336 143 0.022
single organism biosynthetic process GO:0044711 342 0.022
cellular response to peptide GO:1901653 133 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
protein polymerization GO:0051258 22 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
response to external biotic stimulus GO:0043207 221 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.022
gliogenesis GO:0042063 93 0.022
cellular response to growth factor stimulus GO:0071363 162 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
cytoplasmic transport GO:0016482 115 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
regulation of system process GO:0044057 208 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
cell type specific apoptotic process GO:0097285 134 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
intracellular protein transport GO:0006886 79 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.020
positive regulation of signaling GO:0023056 270 0.020
small molecule catabolic process GO:0044282 59 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
cellular amino acid biosynthetic process GO:0008652 32 0.020
response to ketone GO:1901654 182 0.020
regulation of ion transport GO:0043269 245 0.020
homeostatic process GO:0042592 331 0.020
protein complex assembly GO:0006461 263 0.020
positive regulation of molecular function GO:0044093 230 0.020
organophosphate metabolic process GO:0019637 370 0.020
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
calcium ion homeostasis GO:0055074 162 0.020
intracellular signal transduction GO:0035556 314 0.020
Human
developmental process involved in reproduction GO:0003006 159 0.020
positive regulation of ion transport GO:0043270 94 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
response to hypoxia GO:0001666 231 0.019
aging GO:0007568 241 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
regulation of secretion GO:0051046 224 0.019
cellular component morphogenesis GO:0032989 155 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
positive regulation of signal transduction GO:0009967 175 0.019
regulation of protein modification process GO:0031399 194 0.019
Human
response to molecule of bacterial origin GO:0002237 194 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
protein localization GO:0008104 191 0.018
regulation of kinase activity GO:0043549 117 0.018
Human
negative regulation of protein maturation GO:1903318 47 0.018
response to glucocorticoid GO:0051384 223 0.018
response to oxidative stress GO:0006979 186 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
sexual reproduction GO:0019953 148 0.018
establishment of protein localization GO:0045184 141 0.018
positive regulation of organelle organization GO:0010638 48 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
Human
blood circulation GO:0008015 183 0.018
schwann cell migration GO:0036135 2 0.018
nucleotide catabolic process GO:0009166 139 0.018
positive regulation of hydrolase activity GO:0051345 86 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
response to vitamin GO:0033273 131 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
nucleotide metabolic process GO:0009117 279 0.017
tissue development GO:0009888 252 0.017
regulation of secretion by cell GO:1903530 208 0.017
negative regulation of molecular function GO:0044092 133 0.017
Human
regulation of nucleotide metabolic process GO:0006140 117 0.017
reproduction GO:0000003 245 0.017
protein maturation GO:0051604 68 0.017
chemical homeostasis GO:0048878 292 0.017
ion homeostasis GO:0050801 212 0.017
response to acid chemical GO:0001101 222 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
small gtpase mediated signal transduction GO:0007264 36 0.016
protein processing GO:0016485 68 0.016
negative regulation of catalytic activity GO:0043086 103 0.016
Human
cell projection morphogenesis GO:0048858 123 0.016
purine containing compound catabolic process GO:0072523 138 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
Human
purine containing compound metabolic process GO:0072521 253 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
heterocycle catabolic process GO:0046700 167 0.016
positive regulation of gene expression GO:0010628 244 0.016
ras protein signal transduction GO:0007265 29 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
negative regulation of transport GO:0051051 136 0.016
intermediate filament based process GO:0045103 3 0.016
ribonucleoside catabolic process GO:0042454 126 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
response to lipopolysaccharide GO:0032496 191 0.015
alpha amino acid catabolic process GO:1901606 20 0.015
positive regulation of cell development GO:0010720 176 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
regulation of transferase activity GO:0051338 123 0.015
Human
cell growth GO:0016049 104 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
cell cycle checkpoint GO:0000075 2 0.015
proteolysis GO:0006508 175 0.015
cellular component movement GO:0006928 248 0.015
negative regulation of neuron death GO:1901215 69 0.015
sequestering of calcium ion GO:0051208 8 0.015
nucleoside metabolic process GO:0009116 179 0.015
response to alkaloid GO:0043279 132 0.014
cellular amino acid catabolic process GO:0009063 21 0.014
response to cytokine GO:0034097 215 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
oxidation reduction process GO:0055114 304 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of body fluid levels GO:0050878 90 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
cell migration GO:0016477 197 0.014
immune response GO:0006955 104 0.014
negative regulation of microtubule depolymerization GO:0007026 3 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
localization of cell GO:0051674 202 0.014
axis specification GO:0009798 4 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
behavior GO:0007610 205 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of phosphorylation GO:0042325 248 0.013
Human
female pregnancy GO:0007565 122 0.013
carboxylic acid catabolic process GO:0046395 49 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
Human
negative regulation of cell proliferation GO:0008285 119 0.013
circulatory system process GO:0003013 183 0.013
single organism intracellular transport GO:1902582 166 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
regulation of cell cycle GO:0051726 73 0.013
gland development GO:0048732 155 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
regulation of axonogenesis GO:0050770 37 0.013
cellular protein localization GO:0034613 122 0.013
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
camera type eye morphogenesis GO:0048593 2 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
cell cycle GO:0007049 101 0.013
regulation of response to stress GO:0080134 126 0.013
regulation of immune system process GO:0002682 123 0.013
intermediate filament bundle assembly GO:0045110 1 0.013
positive regulation of developmental process GO:0051094 283 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
lipid metabolic process GO:0006629 283 0.012
sequestering of metal ion GO:0051238 9 0.012
response to ammonium ion GO:0060359 71 0.012
release of cytochrome c from mitochondria GO:0001836 8 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
spindle organization GO:0007051 2 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
growth GO:0040007 165 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of purine nucleotide catabolic process GO:0033121 65 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
negative regulation of neuron apoptotic process GO:0043524 45 0.012
response to purine containing compound GO:0014074 126 0.012
male mating behavior GO:0060179 3 0.012
response to other organism GO:0051707 220 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
cell morphogenesis GO:0000902 142 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
multi multicellular organism process GO:0044706 138 0.012
response to corticosteroid GO:0031960 235 0.012
response to zinc ion GO:0010043 39 0.012
organic acid catabolic process GO:0016054 49 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
regulation of protein maturation GO:1903317 50 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
regulation of metal ion transport GO:0010959 118 0.011
metal ion transport GO:0030001 289 0.011
gtp catabolic process GO:0006184 71 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
peptidyl amino acid modification GO:0018193 126 0.011
apoptotic signaling pathway GO:0097190 27 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
transmembrane transport GO:0055085 412 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.011
Human
cellular chemical homeostasis GO:0055082 247 0.011
lipid biosynthetic process GO:0008610 128 0.011
defense response GO:0006952 194 0.011
macroautophagy GO:0016236 4 0.011
regulation of cellular component size GO:0032535 51 0.011
neuron projection regeneration GO:0031102 35 0.011
nucleoside catabolic process GO:0009164 126 0.011
cellular protein complex assembly GO:0043623 44 0.011
response to estradiol GO:0032355 164 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
response to bacterium GO:0009617 200 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
calcium ion transport GO:0006816 131 0.011
regulation of hormone levels GO:0010817 187 0.011
retina morphogenesis in camera type eye GO:0060042 1 0.011
negative regulation of cell communication GO:0010648 158 0.011
Human
carbohydrate catabolic process GO:0016052 40 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
Human
neurotransmitter uptake GO:0001504 3 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
organelle localization GO:0051640 55 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
regulation of protein processing GO:0070613 50 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
circulatory system development GO:0072359 134 0.010
regulation of schwann cell migration GO:1900147 2 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
axon regeneration GO:0031103 28 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
regulation of cellular localization GO:0060341 263 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
intermediate filament cytoskeleton organization GO:0045104 3 0.010
response to organophosphorus GO:0046683 102 0.010
regulation of synaptic transmission GO:0050804 141 0.010
maintenance of location GO:0051235 17 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
organic hydroxy compound transport GO:0015850 77 0.010
actin cytoskeleton organization GO:0030036 73 0.010
cellular homeostasis GO:0019725 252 0.010
regulation of protein kinase activity GO:0045859 105 0.010
Human
positive regulation of microtubule polymerization or depolymerization GO:0031112 7 0.010
response to heat GO:0009408 60 0.010
synaptic transmission GO:0007268 235 0.010
response to amino acid GO:0043200 75 0.010
regulation of extent of cell growth GO:0061387 25 0.010
actin filament based process GO:0030029 86 0.010

Uchl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.010