Rattus norvegicus

0 known processes

Nphs2

nephrosis 2 homolog (human)

(Aliases: podocin,MGC112589)

Nphs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.046
homeostatic process GO:0042592 331 0.045
organic acid metabolic process GO:0006082 292 0.042
oxoacid metabolic process GO:0043436 290 0.042
cellular response to oxygen containing compound GO:1901701 386 0.039
ion transmembrane transport GO:0034220 365 0.039
response to extracellular stimulus GO:0009991 380 0.038
carboxylic acid metabolic process GO:0019752 289 0.037
cellular amino acid metabolic process GO:0006520 107 0.036
metal ion transport GO:0030001 289 0.036
single organism biosynthetic process GO:0044711 342 0.036
response to nutrient levels GO:0031667 370 0.035
chemical homeostasis GO:0048878 292 0.034
cellular chemical homeostasis GO:0055082 247 0.034
reproductive process GO:0022414 372 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
intracellular signal transduction GO:0035556 314 0.032
cation transport GO:0006812 382 0.032
single organism reproductive process GO:0044702 297 0.032
organophosphate metabolic process GO:0019637 370 0.031
cellular component assembly GO:0022607 360 0.031
cellular amine metabolic process GO:0044106 38 0.031
transmembrane transport GO:0055085 412 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
g protein coupled receptor signaling pathway GO:0007186 242 0.030
regulation of cell proliferation GO:0042127 359 0.030
regulation of molecular function GO:0065009 398 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
multi organism reproductive process GO:0044703 262 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.028
cation homeostasis GO:0055080 195 0.028
amine metabolic process GO:0009308 38 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
cellular component biogenesis GO:0044085 368 0.027
neuron differentiation GO:0030182 368 0.027
secretion GO:0046903 307 0.027
catabolic process GO:0009056 351 0.027
regulation of cellular localization GO:0060341 263 0.027
central nervous system development GO:0007417 311 0.027
cellular homeostasis GO:0019725 252 0.027
cellular ketone metabolic process GO:0042180 51 0.026
regulation of cell differentiation GO:0045595 320 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
negative regulation of metabolic process GO:0009892 331 0.026
ion homeostasis GO:0050801 212 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
lipid metabolic process GO:0006629 283 0.025
cellular response to stress GO:0033554 269 0.025
cellular cation homeostasis GO:0030003 180 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
rna biosynthetic process GO:0032774 380 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
regulation of rna metabolic process GO:0051252 391 0.025
multicellular organism reproduction GO:0032504 233 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
positive regulation of biosynthetic process GO:0009891 319 0.024
transcription dna templated GO:0006351 377 0.024
positive regulation of molecular function GO:0044093 230 0.024
cell cell signaling GO:0007267 335 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
blood circulation GO:0008015 183 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
cation transmembrane transport GO:0098655 263 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
regulation of ion transport GO:0043269 245 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
positive regulation of transport GO:0051050 245 0.024
nucleic acid templated transcription GO:0097659 379 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
negative regulation of cell death GO:0060548 229 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
reproduction GO:0000003 245 0.023
response to peptide GO:1901652 292 0.023
regulation of cellular component organization GO:0051128 368 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
single organism catabolic process GO:0044712 283 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
regulation of secretion by cell GO:1903530 208 0.023
nucleotide metabolic process GO:0009117 279 0.023
neuron projection development GO:0031175 273 0.023
head development GO:0060322 247 0.023
regulation of apoptotic process GO:0042981 335 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
regulation of catalytic activity GO:0050790 304 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
cellular ion homeostasis GO:0006873 184 0.022
positive regulation of signaling GO:0023056 270 0.022
cellular response to lipid GO:0071396 201 0.022
metal ion homeostasis GO:0055065 186 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
neuron development GO:0048666 286 0.022
macromolecular complex assembly GO:0065003 273 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
response to corticosteroid GO:0031960 235 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
secretion by cell GO:0032940 248 0.022
response to acid chemical GO:0001101 222 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
brain development GO:0007420 247 0.022
protein complex biogenesis GO:0070271 263 0.022
protein complex subunit organization GO:0071822 302 0.022
protein phosphorylation GO:0006468 345 0.022
response to estrogen GO:0043627 232 0.022
cellular metal ion homeostasis GO:0006875 172 0.021
response to metal ion GO:0010038 253 0.021
apoptotic process GO:0006915 381 0.021
positive regulation of gene expression GO:0010628 244 0.021
regulation of transcription dna templated GO:0006355 374 0.021
response to oxidative stress GO:0006979 186 0.021
positive regulation of developmental process GO:0051094 283 0.021
intracellular transport GO:0046907 185 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
cellular catabolic process GO:0044248 295 0.021
regulation of nervous system development GO:0051960 264 0.021
cell projection organization GO:0030030 302 0.021
anion transport GO:0006820 178 0.021
organic substance catabolic process GO:1901575 316 0.021
cellular lipid metabolic process GO:0044255 208 0.021
response to oxygen levels GO:0070482 265 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
regulation of phosphorylation GO:0042325 248 0.020
regulation of cell development GO:0060284 263 0.020
regulation of protein metabolic process GO:0051246 289 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
regulation of programmed cell death GO:0043067 341 0.020
tissue development GO:0009888 252 0.020
Human
defense response GO:0006952 194 0.020
response to decreased oxygen levels GO:0036293 237 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
regulation of system process GO:0044057 208 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
programmed cell death GO:0012501 392 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
regulation of hormone levels GO:0010817 187 0.020
synaptic transmission GO:0007268 235 0.020
calcium ion homeostasis GO:0055074 162 0.020
regulation of signal transduction GO:0009966 318 0.019
aging GO:0007568 241 0.019
organic acid transport GO:0015849 116 0.019
organelle organization GO:0006996 266 0.019
Human
regulation of intracellular signal transduction GO:1902531 218 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of membrane potential GO:0042391 110 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
regeneration GO:0031099 163 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
circulatory system process GO:0003013 183 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
single organism intracellular transport GO:1902582 166 0.019
neurological system process GO:0050877 219 0.019
ribonucleoside metabolic process GO:0009119 174 0.018
developmental process involved in reproduction GO:0003006 159 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
regulation of neuron differentiation GO:0045664 208 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
response to glucocorticoid GO:0051384 223 0.018
regulation of neurogenesis GO:0050767 247 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
nitrogen compound transport GO:0071705 229 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
cellular component movement GO:0006928 248 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
nucleoside metabolic process GO:0009116 179 0.018
muscle system process GO:0003012 115 0.018
response to nutrient GO:0007584 248 0.018
rna metabolic process GO:0016070 406 0.018
macromolecule localization GO:0033036 252 0.018
positive regulation of catalytic activity GO:0043085 184 0.017
negative regulation of transport GO:0051051 136 0.017
sexual reproduction GO:0019953 148 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
response to carbohydrate GO:0009743 183 0.017
response to wounding GO:0009611 254 0.017
positive regulation of cell communication GO:0010647 271 0.017
response to peptide hormone GO:0043434 278 0.017
regulation of secretion GO:0051046 224 0.017
negative regulation of gene expression GO:0010629 199 0.017
oxidation reduction process GO:0055114 304 0.017
carboxylic acid transport GO:0046942 115 0.017
response to monosaccharide GO:0034284 159 0.017
behavior GO:0007610 205 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
response to radiation GO:0009314 137 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
growth GO:0040007 165 0.017
cellular response to external stimulus GO:0071496 118 0.016
calcium ion transport GO:0006816 131 0.016
protein complex assembly GO:0006461 263 0.016
response to ketone GO:1901654 182 0.016
divalent inorganic cation transport GO:0072511 134 0.016
response to ethanol GO:0045471 162 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
circulatory system development GO:0072359 134 0.016
organic anion transport GO:0015711 132 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
response to bacterium GO:0009617 200 0.016
positive regulation of ion transport GO:0043270 94 0.016
regulation of metal ion transport GO:0010959 118 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
regulation of cell projection organization GO:0031344 175 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
hormone transport GO:0009914 121 0.016
response to hypoxia GO:0001666 231 0.016
small molecule biosynthetic process GO:0044283 124 0.016
single organism organelle organization GO:1902589 180 0.015
Human
response to glucose GO:0009749 136 0.015
response to biotic stimulus GO:0009607 226 0.015
ras protein signal transduction GO:0007265 29 0.015
response to growth factor GO:0070848 189 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
response to lipopolysaccharide GO:0032496 191 0.015
localization of cell GO:0051674 202 0.015
protein localization GO:0008104 191 0.015
response to estradiol GO:0032355 164 0.015
heart morphogenesis GO:0003007 3 0.015
lipid biosynthetic process GO:0008610 128 0.015
protein oligomerization GO:0051259 191 0.015
response to external biotic stimulus GO:0043207 221 0.015
signal release GO:0023061 145 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
wound healing GO:0042060 122 0.015
positive regulation of secretion GO:0051047 140 0.015
inflammatory response GO:0006954 150 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
regulation of synaptic transmission GO:0050804 141 0.014
gamete generation GO:0007276 124 0.014
gastrulation GO:0007369 2 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
response to hexose GO:0009746 144 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
regulation of protein modification process GO:0031399 194 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
response to reactive oxygen species GO:0000302 120 0.014
positive regulation of cell development GO:0010720 176 0.014
mapk cascade GO:0000165 140 0.014
anterior posterior pattern specification GO:0009952 1 0.014
proteolysis GO:0006508 175 0.014
response to cytokine GO:0034097 215 0.014
rhythmic process GO:0048511 156 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
positive regulation of signal transduction GO:0009967 175 0.014
regulation of homeostatic process GO:0032844 101 0.014
divalent metal ion transport GO:0070838 132 0.014
response to other organism GO:0051707 220 0.014
regulation of neuron projection development GO:0010975 161 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of anatomical structure size GO:0090066 135 0.013
negative regulation of cell communication GO:0010648 158 0.013
reproductive system development GO:0061458 128 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
establishment of tissue polarity GO:0007164 2 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
hormone secretion GO:0046879 115 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to alkaloid GO:0043279 132 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
gland development GO:0048732 155 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
cell part morphogenesis GO:0032990 123 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
regulation of blood circulation GO:1903522 110 0.013
action potential GO:0001508 54 0.013
response to vitamin GO:0033273 131 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
cellular response to alcohol GO:0097306 87 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
axis specification GO:0009798 4 0.013
cardiovascular system development GO:0072358 134 0.013
reproductive structure development GO:0048608 128 0.013
positive regulation of nervous system development GO:0051962 178 0.013
cellular response to peptide GO:1901653 133 0.013
response to mechanical stimulus GO:0009612 134 0.013
positive regulation of protein modification process GO:0031401 142 0.013
aromatic compound catabolic process GO:0019439 168 0.013
multi multicellular organism process GO:0044706 138 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
cytoplasmic transport GO:0016482 115 0.012
regulation of catabolic process GO:0009894 113 0.012
sequestering of metal ion GO:0051238 9 0.012
regulation of hydrolase activity GO:0051336 143 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
carbohydrate metabolic process GO:0005975 130 0.012
maintenance of location GO:0051235 17 0.012
chromosome segregation GO:0007059 2 0.012
muscle contraction GO:0006936 88 0.012
development of primary sexual characteristics GO:0045137 107 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
regulation of hormone secretion GO:0046883 106 0.012
sequestering of calcium ion GO:0051208 8 0.012
positive regulation of cell death GO:0010942 184 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
vascular process in circulatory system GO:0003018 96 0.012
cell morphogenesis GO:0000902 142 0.012
regulation of transmembrane transport GO:0034762 122 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
locomotion GO:0040011 237 0.012
female pregnancy GO:0007565 122 0.012
establishment of protein localization GO:0045184 141 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
nucleotide catabolic process GO:0009166 139 0.012
forebrain development GO:0030900 98 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
multicellular organismal signaling GO:0035637 44 0.012
cellular component morphogenesis GO:0032989 155 0.012
regulation of kinase activity GO:0043549 117 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
response to toxic substance GO:0009636 133 0.012
immune system process GO:0002376 204 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
heterocycle catabolic process GO:0046700 167 0.012
eye morphogenesis GO:0048592 4 0.012
vesicle mediated transport GO:0016192 181 0.012
potassium ion transport GO:0006813 97 0.011
cell migration GO:0016477 197 0.011
chemosensory behavior GO:0007635 2 0.011
amide transport GO:0042886 105 0.011
cell motility GO:0048870 202 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of cellular component movement GO:0051270 150 0.011
regulation of protein kinase activity GO:0045859 105 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
protein transport GO:0015031 132 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
regulation of transferase activity GO:0051338 123 0.011
peptide transport GO:0015833 97 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of signaling GO:0023057 157 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of peptide secretion GO:0002791 82 0.011
regulation of blood vessel size GO:0050880 89 0.011
muscle structure development GO:0061061 87 0.011
cellular protein localization GO:0034613 122 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
response to hydrogen peroxide GO:0042542 89 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
purine containing compound catabolic process GO:0072523 138 0.011
regulation of mapk cascade GO:0043408 116 0.011
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
membrane organization GO:0061024 94 0.011
embryonic appendage morphogenesis GO:0035113 4 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
cell type specific apoptotic process GO:0097285 134 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
cell projection morphogenesis GO:0048858 123 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of body fluid levels GO:0050878 90 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
gliogenesis GO:0042063 93 0.011
organic acid biosynthetic process GO:0016053 83 0.010
cofactor metabolic process GO:0051186 95 0.010
gonad development GO:0008406 104 0.010
peptide hormone secretion GO:0030072 84 0.010
regulation of muscle system process GO:0090257 79 0.010
coenzyme metabolic process GO:0006732 86 0.010
neuronal action potential GO:0019228 35 0.010
lipid storage GO:0019915 1 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
transmission of nerve impulse GO:0019226 42 0.010
anion transmembrane transport GO:0098656 77 0.010
regulation of locomotion GO:0040012 148 0.010
dephosphorylation GO:0016311 98 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
embryonic pattern specification GO:0009880 1 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
male gamete generation GO:0048232 99 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
response to purine containing compound GO:0014074 126 0.010
mesoderm development GO:0007498 2 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of tube size GO:0035150 89 0.010
regulation of response to stress GO:0080134 126 0.010
regulation of blood pressure GO:0008217 83 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
hepaticobiliary system development GO:0061008 90 0.010
negative regulation of innate immune response GO:0045824 4 0.010
peptide secretion GO:0002790 86 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
heart development GO:0007507 72 0.010

Nphs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
Human
nervous system disease DOID:863 0 0.025
musculoskeletal system disease DOID:17 0 0.019
disease of metabolism DOID:0014667 0 0.018
sensory system disease DOID:0050155 0 0.016
cardiovascular system disease DOID:1287 0 0.012
central nervous system disease DOID:331 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
connective tissue disease DOID:65 0 0.011
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010