Rattus norvegicus

0 known processes

Rpa2

replication protein A2

Rpa2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.372
cellular response to endogenous stimulus GO:0071495 377 0.320
rna biosynthetic process GO:0032774 380 0.313
regulation of rna biosynthetic process GO:2001141 381 0.194
protein complex subunit organization GO:0071822 302 0.173
regulation of programmed cell death GO:0043067 341 0.166
transcription from rna polymerase ii promoter GO:0006366 252 0.157
nucleic acid templated transcription GO:0097659 379 0.145
regulation of nucleic acid templated transcription GO:1903506 380 0.143
cellular component assembly GO:0022607 360 0.142
single organism reproductive process GO:0044702 297 0.137
response to estradiol GO:0032355 164 0.131
cellular component biogenesis GO:0044085 368 0.127
regulation of rna metabolic process GO:0051252 391 0.124
single organism biosynthetic process GO:0044711 342 0.121
macromolecular complex subunit organization GO:0043933 339 0.120
catabolic process GO:0009056 351 0.119
response to decreased oxygen levels GO:0036293 237 0.116
positive regulation of transcription dna templated GO:0045893 197 0.116
neurological system process GO:0050877 219 0.115
regulation of molecular function GO:0065009 398 0.113
transcription dna templated GO:0006351 377 0.109
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.100
response to estrogen GO:0043627 232 0.099
cellular catabolic process GO:0044248 295 0.099
negative regulation of cellular biosynthetic process GO:0031327 161 0.096
response to nutrient GO:0007584 248 0.095
pyrimidine nucleobase metabolic process GO:0006206 8 0.094
regulation of cell proliferation GO:0042127 359 0.093
macromolecular complex assembly GO:0065003 273 0.092
apoptotic process GO:0006915 381 0.091
response to extracellular stimulus GO:0009991 380 0.091
organic substance catabolic process GO:1901575 316 0.088
response to nutrient levels GO:0031667 370 0.086
positive regulation of gene expression GO:0010628 244 0.085
macromolecule localization GO:0033036 252 0.083
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.083
cellular nitrogen compound catabolic process GO:0044270 163 0.082
positive regulation of rna metabolic process GO:0051254 203 0.080
programmed cell death GO:0012501 392 0.080
regulation of apoptotic process GO:0042981 335 0.080
regulation of catalytic activity GO:0050790 304 0.079
response to amino acid GO:0043200 75 0.079
rna metabolic process GO:0016070 406 0.079
chromatin assembly or disassembly GO:0006333 1 0.077
negative regulation of nucleic acid templated transcription GO:1903507 117 0.076
organelle organization GO:0006996 266 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.075
carboxylic acid metabolic process GO:0019752 289 0.074
response to oxygen levels GO:0070482 265 0.072
protein phosphorylation GO:0006468 345 0.072
response to cadmium ion GO:0046686 35 0.072
protein complex biogenesis GO:0070271 263 0.070
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.069
protein transport GO:0015031 132 0.069
protein complex assembly GO:0006461 263 0.067
cellular response to stress GO:0033554 269 0.067
behavior GO:0007610 205 0.066
reproductive process GO:0022414 372 0.066
response to hypoxia GO:0001666 231 0.066
response to metal ion GO:0010038 253 0.066
organophosphate metabolic process GO:0019637 370 0.064
negative regulation of metabolic process GO:0009892 331 0.064
transforming growth factor beta3 production GO:0032907 2 0.061
cellular response to oxygen containing compound GO:1901701 386 0.060
reproduction GO:0000003 245 0.059
nucleoside triphosphate catabolic process GO:0009143 123 0.058
cellular response to organonitrogen compound GO:0071417 197 0.058
response to inorganic substance GO:0010035 377 0.058
response to acid chemical GO:0001101 222 0.057
nucleoside phosphate metabolic process GO:0006753 283 0.057
cellular component movement GO:0006928 248 0.056
regulation of cellular component organization GO:0051128 368 0.056
single organism behavior GO:0044708 130 0.056
nucleosome organization GO:0034728 1 0.055
positive regulation of apoptotic process GO:0043065 154 0.055
organonitrogen compound biosynthetic process GO:1901566 167 0.053
cellular protein localization GO:0034613 122 0.053
establishment of protein localization GO:0045184 141 0.053
response to growth factor GO:0070848 189 0.052
lipid metabolic process GO:0006629 283 0.051
positive regulation of cellular biosynthetic process GO:0031328 295 0.051
tissue development GO:0009888 252 0.051
organic acid metabolic process GO:0006082 292 0.050
dna metabolic process GO:0006259 96 0.050
tetrahydrofolate metabolic process GO:0046653 9 0.050
positive regulation of biosynthetic process GO:0009891 319 0.050
response to ethanol GO:0045471 162 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.050
cellular response to organic cyclic compound GO:0071407 202 0.049
oxoacid metabolic process GO:0043436 290 0.049
negative regulation of gene expression GO:0010629 199 0.049
positive regulation of rna biosynthetic process GO:1902680 197 0.047
positive regulation of retinal cell programmed cell death GO:0046670 1 0.047
developmental process involved in reproduction GO:0003006 159 0.046
cellular response to peptide hormone stimulus GO:0071375 120 0.046
regulation of growth GO:0040008 105 0.046
purine containing compound metabolic process GO:0072521 253 0.046
regulation of response to stress GO:0080134 126 0.046
cellular amino acid metabolic process GO:0006520 107 0.045
response to ketone GO:1901654 182 0.045
protein localization GO:0008104 191 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
cell cycle checkpoint GO:0000075 2 0.043
cellular macromolecule localization GO:0070727 122 0.043
circadian regulation of gene expression GO:0032922 3 0.043
multi organism reproductive process GO:0044703 262 0.043
response to reactive oxygen species GO:0000302 120 0.043
sexual reproduction GO:0019953 148 0.042
positive regulation of developmental process GO:0051094 283 0.042
negative regulation of rna biosynthetic process GO:1902679 118 0.042
response to peptide hormone GO:0043434 278 0.042
cell cycle GO:0007049 101 0.041
positive regulation of cell death GO:0010942 184 0.040
cellular response to hormone stimulus GO:0032870 247 0.040
cognition GO:0050890 92 0.040
learning or memory GO:0007611 90 0.040
aromatic compound catabolic process GO:0019439 168 0.039
gonad development GO:0008406 104 0.039
negative regulation of programmed cell death GO:0043069 183 0.039
cardiovascular system development GO:0072358 134 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
organic cyclic compound catabolic process GO:1901361 175 0.038
neuron differentiation GO:0030182 368 0.037
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.036
negative regulation of cell proliferation GO:0008285 119 0.035
nucleobase containing compound catabolic process GO:0034655 152 0.035
locomotion GO:0040011 237 0.035
mitotic cell cycle phase transition GO:0044772 20 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
growth GO:0040007 165 0.034
nucleoside triphosphate metabolic process GO:0009141 144 0.033
nucleocytoplasmic transport GO:0006913 48 0.033
brain development GO:0007420 247 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
purine ribonucleoside metabolic process GO:0046128 168 0.033
positive regulation of programmed cell death GO:0043068 157 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
organ regeneration GO:0031100 101 0.032
cellular response to external stimulus GO:0071496 118 0.032
double strand break repair GO:0006302 1 0.032
nucleoside phosphate biosynthetic process GO:1901293 102 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
meiosis i GO:0007127 2 0.032
axis specification GO:0009798 4 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
heterocycle catabolic process GO:0046700 167 0.031
positive regulation of cell proliferation GO:0008284 249 0.031
forebrain development GO:0030900 98 0.031
gamete generation GO:0007276 124 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
response to radiation GO:0009314 137 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
folic acid containing compound metabolic process GO:0006760 10 0.028
single organism catabolic process GO:0044712 283 0.028
ribonucleoside monophosphate metabolic process GO:0009161 88 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
purine ribonucleotide metabolic process GO:0009150 227 0.028
aging GO:0007568 241 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
regeneration GO:0031099 163 0.028
intracellular signal transduction GO:0035556 314 0.028
nucleotide metabolic process GO:0009117 279 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
purine nucleotide metabolic process GO:0006163 229 0.027
cellular response to lipid GO:0071396 201 0.027
negative regulation of cell cycle phase transition GO:1901988 4 0.027
cellular modified amino acid metabolic process GO:0006575 61 0.027
cellular modified amino acid biosynthetic process GO:0042398 18 0.027
meiotic cell cycle process GO:1903046 3 0.027
male sex differentiation GO:0046661 64 0.027
mitotic cell cycle GO:0000278 49 0.026
cell cell signaling GO:0007267 335 0.026
response to wounding GO:0009611 254 0.026
response to mechanical stimulus GO:0009612 134 0.026
organonitrogen compound catabolic process GO:1901565 179 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
circulatory system development GO:0072359 134 0.025
wound healing GO:0042060 122 0.025
development of primary sexual characteristics GO:0045137 107 0.025
reproductive system development GO:0061458 128 0.025
mitotic dna damage checkpoint GO:0044773 1 0.025
positive regulation of response to stimulus GO:0048584 285 0.024
head development GO:0060322 247 0.024
intracellular transport GO:0046907 185 0.024
response to toxic substance GO:0009636 133 0.024
gland development GO:0048732 155 0.024
response to purine containing compound GO:0014074 126 0.024
negative regulation of cell death GO:0060548 229 0.024
developmental growth GO:0048589 100 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
response to anoxia GO:0034059 4 0.024
spermatogenesis GO:0007283 99 0.024
cellular response to nitrogen compound GO:1901699 210 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
nucleoside monophosphate metabolic process GO:0009123 93 0.023
regulation of developmental growth GO:0048638 45 0.023
neuronal action potential GO:0019228 35 0.023
cellular response to insulin stimulus GO:0032869 81 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
central nervous system development GO:0007417 311 0.023
secretion GO:0046903 307 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
chromosome segregation GO:0007059 2 0.022
cellular ketone metabolic process GO:0042180 51 0.022
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.022
response to transition metal nanoparticle GO:1990267 122 0.021
regulation of protein metabolic process GO:0051246 289 0.021
response to peptide GO:1901652 292 0.021
action potential GO:0001508 54 0.021
nucleotide biosynthetic process GO:0009165 98 0.021
response to lipopolysaccharide GO:0032496 191 0.021
sensory organ development GO:0007423 74 0.021
positive regulation of response to external stimulus GO:0032103 51 0.021
regulation of cell cycle GO:0051726 73 0.021
positive regulation of cell communication GO:0010647 271 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.021
nucleotide catabolic process GO:0009166 139 0.021
muscle structure development GO:0061061 87 0.020
multicellular organism reproduction GO:0032504 233 0.020
negative regulation of cell communication GO:0010648 158 0.020
cellular lipid metabolic process GO:0044255 208 0.020
intracellular protein transport GO:0006886 79 0.020
protein oligomerization GO:0051259 191 0.020
response to glucocorticoid GO:0051384 223 0.020
nucleoside metabolic process GO:0009116 179 0.019
defense response GO:0006952 194 0.019
response to alkaloid GO:0043279 132 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
eye morphogenesis GO:0048592 4 0.019
reproductive structure development GO:0048608 128 0.019
renal system development GO:0072001 67 0.019
mitotic cell cycle checkpoint GO:0007093 1 0.019
positive regulation of secretion GO:0051047 140 0.019
chromatin remodeling GO:0006338 3 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
purine nucleoside catabolic process GO:0006152 124 0.018
alpha amino acid metabolic process GO:1901605 71 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
cellular response to dna damage stimulus GO:0006974 19 0.018
cell cycle g1 s phase transition GO:0044843 13 0.018
neuron development GO:0048666 286 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
response to corticosteroid GO:0031960 235 0.018
interleukin 1 beta secretion GO:0050702 3 0.018
muscle organ development GO:0007517 50 0.018
organophosphate catabolic process GO:0046434 148 0.018
response to vitamin GO:0033273 131 0.018
response to testosterone GO:0033574 55 0.018
mitotic spindle organization GO:0007052 2 0.018
transmission of nerve impulse GO:0019226 42 0.018
bmp signaling pathway GO:0030509 4 0.018
glycosyl compound metabolic process GO:1901657 182 0.017
amine metabolic process GO:0009308 38 0.017
cell migration GO:0016477 197 0.017
regulation of membrane potential GO:0042391 110 0.017
cellular macromolecular complex assembly GO:0034622 58 0.017
dna packaging GO:0006323 4 0.017
pteridine containing compound metabolic process GO:0042558 14 0.017
nucleoside monophosphate biosynthetic process GO:0009124 28 0.017
single organism organelle organization GO:1902589 180 0.017
epithelial cell differentiation GO:0030855 71 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
embryonic pattern specification GO:0009880 1 0.017
cell morphogenesis GO:0000902 142 0.017
positive regulation of molecular function GO:0044093 230 0.017
localization of cell GO:0051674 202 0.016
response to ionizing radiation GO:0010212 59 0.016
positive regulation of signal transduction GO:0009967 175 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
cellular amine metabolic process GO:0044106 38 0.016
male gamete generation GO:0048232 99 0.016
deoxyribose phosphate metabolic process GO:0019692 9 0.016
cell cycle process GO:0022402 57 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
nitrogen compound transport GO:0071705 229 0.016
centrosome organization GO:0051297 1 0.016
deoxyribonucleotide biosynthetic process GO:0009263 6 0.016
positive regulation of cardiac muscle tissue development GO:0055025 9 0.016
cellular response to reactive oxygen species GO:0034614 55 0.015
positive regulation of lipid catabolic process GO:0050996 4 0.015
response to oxidative stress GO:0006979 186 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.015
cellular response to peptide GO:1901653 133 0.015
rhythmic process GO:0048511 156 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
positive regulation of transport GO:0051050 245 0.015
multicellular organism growth GO:0035264 1 0.015
ventricular cardiac muscle cell development GO:0055015 2 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
spindle organization GO:0007051 2 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
deoxyribonucleoside monophosphate metabolic process GO:0009162 6 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
limb morphogenesis GO:0035108 4 0.014
cellular response to inorganic substance GO:0071241 65 0.014
single organism intracellular transport GO:1902582 166 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
cell part morphogenesis GO:0032990 123 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
response to bacterium GO:0009617 200 0.014
homeostatic process GO:0042592 331 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
embryonic appendage morphogenesis GO:0035113 4 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
lens development in camera type eye GO:0002088 13 0.014
regulation of cellular localization GO:0060341 263 0.014
ensheathment of neurons GO:0007272 40 0.014
regulation of organ growth GO:0046620 13 0.014
organ morphogenesis GO:0009887 75 0.014
negative regulation of signal transduction GO:0009968 83 0.014
response to epidermal growth factor GO:0070849 18 0.014
response to amine GO:0014075 46 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
neuron projection development GO:0031175 273 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
regulation of nucleocytoplasmic transport GO:0046822 28 0.013
anion transport GO:0006820 178 0.013
regulation of signal transduction GO:0009966 318 0.013
jak stat cascade GO:0007259 26 0.013
regulation of hydrolase activity GO:0051336 143 0.013
centrosome cycle GO:0007098 1 0.013
regulation of kinase activity GO:0043549 117 0.013
response to insulin GO:0032868 133 0.013
regulation of organelle organization GO:0033043 80 0.013
vasculature development GO:0001944 70 0.013
regulation of secretion GO:0051046 224 0.013
regulation of protein localization GO:0032880 81 0.013
single organism nuclear import GO:1902593 35 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
response to cobalt ion GO:0032025 12 0.013
protein targeting GO:0006605 61 0.013
dna replication GO:0006260 37 0.012
cellular response to oxidative stress GO:0034599 76 0.012
male gonad development GO:0008584 59 0.012
nucleoside monophosphate catabolic process GO:0009125 56 0.012
camera type eye development GO:0043010 48 0.012
regulation of cardiac muscle tissue growth GO:0055021 12 0.012
multicellular organismal signaling GO:0035637 44 0.012
inflammatory response GO:0006954 150 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of adherens junction organization GO:1903393 2 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
dna integrity checkpoint GO:0031570 2 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
positive regulation of interleukin 1 secretion GO:0050716 3 0.012
regulation of microtubule based process GO:0032886 14 0.012
response to carbohydrate GO:0009743 183 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
memory GO:0007613 54 0.012
protein maturation GO:0051604 68 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.011
regulation of cell migration GO:0030334 128 0.011
peptidyl amino acid modification GO:0018193 126 0.011
mrna metabolic process GO:0016071 20 0.011
regulation of muscle organ development GO:0048634 26 0.011
kidney development GO:0001822 67 0.011
nuclear transport GO:0051169 49 0.011
positive regulation of signaling GO:0023056 270 0.011
heart development GO:0007507 72 0.011
chemical homeostasis GO:0048878 292 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
cell cycle phase transition GO:0044770 21 0.011
purine containing compound catabolic process GO:0072523 138 0.011
appendage morphogenesis GO:0035107 4 0.011
palate development GO:0060021 2 0.011
embryonic axis specification GO:0000578 1 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of protein transport GO:0051223 68 0.011
cytoskeleton organization GO:0007010 111 0.011
protein sumoylation GO:0016925 4 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
response to other organism GO:0051707 220 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
dna recombination GO:0006310 3 0.011
2 deoxyribonucleotide biosynthetic process GO:0009265 6 0.011
regulation of microtubule cytoskeleton organization GO:0070507 14 0.011
regulation of interleukin 1 beta production GO:0032651 7 0.011
cellular component morphogenesis GO:0032989 155 0.011
protein homooligomerization GO:0051260 91 0.011
regulation of response to external stimulus GO:0032101 106 0.011
nucleoside catabolic process GO:0009164 126 0.011
establishment of protein localization to organelle GO:0072594 44 0.011
organic acid biosynthetic process GO:0016053 83 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
circadian rhythm GO:0007623 88 0.010
regulation of retinal cell programmed cell death GO:0046668 1 0.010
response to cytokine GO:0034097 215 0.010
negative regulation of signaling GO:0023057 157 0.010
axon ensheathment GO:0008366 40 0.010
dna damage checkpoint GO:0000077 2 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
rna localization GO:0006403 4 0.010
single fertilization GO:0007338 3 0.010
response to glucose GO:0009749 136 0.010
positive regulation of jak stat cascade GO:0046427 19 0.010

Rpa2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.054
cancer DOID:162 0 0.027
organ system cancer DOID:0050686 0 0.021
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011