Rattus norvegicus

0 known processes

Abca8a

ATP-binding cassette, subfamily A (ABC1), member 8a

Abca8a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.136
ion transmembrane transport GO:0034220 365 0.077
carboxylic acid metabolic process GO:0019752 289 0.068
single organism biosynthetic process GO:0044711 342 0.065
regulation of cellular component organization GO:0051128 368 0.060
regulation of ion transport GO:0043269 245 0.059
organophosphate metabolic process GO:0019637 370 0.059
cellular amino acid metabolic process GO:0006520 107 0.059
positive regulation of signaling GO:0023056 270 0.058
cation transmembrane transport GO:0098655 263 0.055
response to inorganic substance GO:0010035 377 0.054
rna metabolic process GO:0016070 406 0.052
inorganic ion transmembrane transport GO:0098660 229 0.048
regulation of nervous system development GO:0051960 264 0.048
regulation of transcription dna templated GO:0006355 374 0.046
positive regulation of biosynthetic process GO:0009891 319 0.046
regulation of phosphate metabolic process GO:0019220 349 0.046
brain development GO:0007420 247 0.045
regulation of cell projection organization GO:0031344 175 0.045
positive regulation of cell projection organization GO:0031346 111 0.045
intracellular signal transduction GO:0035556 314 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
cation transport GO:0006812 382 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
regulation of phosphorylation GO:0042325 248 0.042
head development GO:0060322 247 0.042
cellular response to endogenous stimulus GO:0071495 377 0.041
cellular amine metabolic process GO:0044106 38 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.041
transcription dna templated GO:0006351 377 0.040
amine metabolic process GO:0009308 38 0.040
regulation of multicellular organismal development GO:2000026 376 0.040
oxoacid metabolic process GO:0043436 290 0.037
inorganic cation transmembrane transport GO:0098662 202 0.037
neurological system process GO:0050877 219 0.036
protein phosphorylation GO:0006468 345 0.036
cell projection organization GO:0030030 302 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.035
cellular component movement GO:0006928 248 0.035
regulation of secretion by cell GO:1903530 208 0.035
regulation of membrane potential GO:0042391 110 0.035
nucleoside phosphate metabolic process GO:0006753 283 0.035
organophosphate biosynthetic process GO:0090407 143 0.033
cellular homeostasis GO:0019725 252 0.033
regulation of cell development GO:0060284 263 0.033
neuron development GO:0048666 286 0.033
regulation of cell differentiation GO:0045595 320 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
regulation of molecular function GO:0065009 398 0.033
positive regulation of developmental process GO:0051094 283 0.033
regulation of protein metabolic process GO:0051246 289 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
central nervous system development GO:0007417 311 0.032
regulation of signal transduction GO:0009966 318 0.032
cellular component biogenesis GO:0044085 368 0.032
transmission of nerve impulse GO:0019226 42 0.032
regulation of neurogenesis GO:0050767 247 0.032
programmed cell death GO:0012501 392 0.032
positive regulation of response to stimulus GO:0048584 285 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
response to nutrient levels GO:0031667 370 0.031
multicellular organismal signaling GO:0035637 44 0.031
positive regulation of neuron projection development GO:0010976 99 0.031
protein localization GO:0008104 191 0.030
positive regulation of protein phosphorylation GO:0001934 135 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
secretion GO:0046903 307 0.030
response to metal ion GO:0010038 253 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
neuron projection development GO:0031175 273 0.030
nucleic acid templated transcription GO:0097659 379 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
cellular ketone metabolic process GO:0042180 51 0.029
organic acid metabolic process GO:0006082 292 0.029
regulation of protein modification process GO:0031399 194 0.028
cellular cation homeostasis GO:0030003 180 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
neuron differentiation GO:0030182 368 0.028
response to extracellular stimulus GO:0009991 380 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
regulation of apoptotic process GO:0042981 335 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
positive regulation of cell communication GO:0010647 271 0.028
positive regulation of cellular component organization GO:0051130 200 0.027
cellular component assembly GO:0022607 360 0.027
action potential GO:0001508 54 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
homeostatic process GO:0042592 331 0.027
negative regulation of transport GO:0051051 136 0.027
response to nutrient GO:0007584 248 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
cellular metal ion homeostasis GO:0006875 172 0.027
rna biosynthetic process GO:0032774 380 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
purine containing compound metabolic process GO:0072521 253 0.026
lipid metabolic process GO:0006629 283 0.026
positive regulation of signal transduction GO:0009967 175 0.026
regulation of neuron differentiation GO:0045664 208 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
protein complex biogenesis GO:0070271 263 0.026
regulation of programmed cell death GO:0043067 341 0.025
apoptotic process GO:0006915 381 0.025
cell cell signaling GO:0007267 335 0.025
cation homeostasis GO:0055080 195 0.025
metal ion transport GO:0030001 289 0.025
cellular ion homeostasis GO:0006873 184 0.025
regulation of rna metabolic process GO:0051252 391 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
cellular lipid metabolic process GO:0044255 208 0.025
locomotion GO:0040011 237 0.024
catabolic process GO:0009056 351 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
neuronal action potential GO:0019228 35 0.024
cellular chemical homeostasis GO:0055082 247 0.024
regulation of cellular localization GO:0060341 263 0.024
negative regulation of cell death GO:0060548 229 0.024
calcium ion homeostasis GO:0055074 162 0.024
positive regulation of secretion GO:0051047 140 0.024
eye morphogenesis GO:0048592 4 0.024
calcium ion transport GO:0006816 131 0.024
positive regulation of phosphorylation GO:0042327 177 0.023
adult locomotory behavior GO:0008344 4 0.023
secretion by cell GO:0032940 248 0.023
metal ion homeostasis GO:0055065 186 0.023
regulation of catalytic activity GO:0050790 304 0.023
regulation of secretion GO:0051046 224 0.023
cellular calcium ion homeostasis GO:0006874 160 0.023
negative regulation of metabolic process GO:0009892 331 0.023
regulation of cell proliferation GO:0042127 359 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
nucleotide metabolic process GO:0009117 279 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
chemical homeostasis GO:0048878 292 0.022
single organism reproductive process GO:0044702 297 0.022
negative regulation of cell communication GO:0010648 158 0.022
nitrogen compound transport GO:0071705 229 0.022
response to acid chemical GO:0001101 222 0.022
macromolecule localization GO:0033036 252 0.022
ribose phosphate metabolic process GO:0019693 235 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
behavior GO:0007610 205 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
positive regulation of molecular function GO:0044093 230 0.021
rhythmic process GO:0048511 156 0.021
single organism catabolic process GO:0044712 283 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
negative regulation of gene expression GO:0010629 199 0.020
ras protein signal transduction GO:0007265 29 0.020
ensheathment of neurons GO:0007272 40 0.020
response to peptide GO:1901652 292 0.020
positive regulation of cell death GO:0010942 184 0.020
regulation of neuron projection development GO:0010975 161 0.020
aging GO:0007568 241 0.020
macromolecular complex subunit organization GO:0043933 339 0.019
positive regulation of nervous system development GO:0051962 178 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
response to ethanol GO:0045471 162 0.019
oxidation reduction process GO:0055114 304 0.019
ion homeostasis GO:0050801 212 0.019
positive regulation of cell development GO:0010720 176 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
organic anion transport GO:0015711 132 0.019
positive regulation of gene expression GO:0010628 244 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
response to other organism GO:0051707 220 0.018
cellular catabolic process GO:0044248 295 0.018
organic substance catabolic process GO:1901575 316 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
blood circulation GO:0008015 183 0.018
regulation of mapk cascade GO:0043408 116 0.018
multicellular organism reproduction GO:0032504 233 0.018
gliogenesis GO:0042063 93 0.018
maintenance of location GO:0051235 17 0.018
proteolysis GO:0006508 175 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
regulation of anatomical structure size GO:0090066 135 0.018
regulation of system process GO:0044057 208 0.017
protein complex assembly GO:0006461 263 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
glial cell differentiation GO:0010001 65 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
organic hydroxy compound transport GO:0015850 77 0.017
response to purine containing compound GO:0014074 126 0.017
cell projection morphogenesis GO:0048858 123 0.017
ribose phosphate biosynthetic process GO:0046390 87 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
axon ensheathment GO:0008366 40 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
synaptic transmission GO:0007268 235 0.017
organic acid transport GO:0015849 116 0.017
divalent metal ion transport GO:0070838 132 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
cellular macromolecule localization GO:0070727 122 0.017
forebrain development GO:0030900 98 0.017
positive regulation of protein modification process GO:0031401 142 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
reproductive process GO:0022414 372 0.016
positive regulation of transport GO:0051050 245 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
carboxylic acid transport GO:0046942 115 0.016
peptidyl amino acid modification GO:0018193 126 0.016
response to cytokine GO:0034097 215 0.016
myelination GO:0042552 39 0.016
intracellular transport GO:0046907 185 0.016
regulation of transmembrane transport GO:0034762 122 0.016
anion transport GO:0006820 178 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
multi organism reproductive process GO:0044703 262 0.016
response to external biotic stimulus GO:0043207 221 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
purine containing compound biosynthetic process GO:0072522 85 0.015
circulatory system process GO:0003013 183 0.015
cellular response to stress GO:0033554 269 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
axis specification GO:0009798 4 0.015
calcium ion transmembrane transport GO:0070588 70 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
reproduction GO:0000003 245 0.015
negative regulation of signaling GO:0023057 157 0.015
growth GO:0040007 165 0.015
circulatory system development GO:0072359 134 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.014
response to wounding GO:0009611 254 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
response to camp GO:0051591 91 0.014
regulation of calcium ion transport GO:0051924 77 0.014
potassium ion transport GO:0006813 97 0.014
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
response to fatty acid GO:0070542 65 0.014
regulation of metal ion transport GO:0010959 118 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
vesicle mediated transport GO:0016192 181 0.014
response to growth factor GO:0070848 189 0.014
cell motility GO:0048870 202 0.014
divalent inorganic cation transport GO:0072511 134 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
regulation of hormone levels GO:0010817 187 0.014
response to biotic stimulus GO:0009607 226 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
nucleoside metabolic process GO:0009116 179 0.014
response to glucocorticoid GO:0051384 223 0.014
cellular protein localization GO:0034613 122 0.013
response to estrogen GO:0043627 232 0.013
cell growth GO:0016049 104 0.013
response to ketone GO:1901654 182 0.013
cell part morphogenesis GO:0032990 123 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
positive regulation of transferase activity GO:0051347 81 0.013
protein oligomerization GO:0051259 191 0.013
single organism membrane organization GO:0044802 74 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
heart contraction GO:0060047 57 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
anion transmembrane transport GO:0098656 77 0.013
retina morphogenesis in camera type eye GO:0060042 1 0.013
macromolecular complex assembly GO:0065003 273 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
cell adhesion GO:0007155 110 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
circadian rhythm GO:0007623 88 0.013
response to bacterium GO:0009617 200 0.013
gastrulation GO:0007369 2 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
cell type specific apoptotic process GO:0097285 134 0.012
positive regulation of blood circulation GO:1903524 65 0.012
single organism behavior GO:0044708 130 0.012
protein complex subunit organization GO:0071822 302 0.012
response to oxidative stress GO:0006979 186 0.012
small molecule biosynthetic process GO:0044283 124 0.012
single organism intracellular transport GO:1902582 166 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
response to oxygen levels GO:0070482 265 0.012
carbohydrate metabolic process GO:0005975 130 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
muscle system process GO:0003012 115 0.012
telencephalon development GO:0021537 62 0.012
single organism cellular localization GO:1902580 102 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
cell cycle checkpoint GO:0000075 2 0.012
cardiovascular system development GO:0072358 134 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
vascular process in circulatory system GO:0003018 96 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
regulation of catabolic process GO:0009894 113 0.012
cytoplasmic transport GO:0016482 115 0.012
coenzyme metabolic process GO:0006732 86 0.012
response to organophosphorus GO:0046683 102 0.012
regulation of synaptic transmission GO:0050804 141 0.011
negative regulation of neuron death GO:1901215 69 0.011
neuron death GO:0070997 127 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
regulation of transferase activity GO:0051338 123 0.011
response to calcium ion GO:0051592 59 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
multicellular organism growth GO:0035264 1 0.011
mapk cascade GO:0000165 140 0.011
biological adhesion GO:0022610 110 0.011
regulation of blood circulation GO:1903522 110 0.011
response to decreased oxygen levels GO:0036293 237 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
cell migration GO:0016477 197 0.011
developmental process involved in reproduction GO:0003006 159 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
cofactor metabolic process GO:0051186 95 0.011
motor neuron axon guidance GO:0008045 1 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
regulation of cell growth GO:0001558 85 0.011
regulation of protein kinase activity GO:0045859 105 0.011
amine transport GO:0015837 57 0.011
phospholipid metabolic process GO:0006644 61 0.011
establishment of protein localization GO:0045184 141 0.011
regulation of organelle organization GO:0033043 80 0.011
response to carbohydrate GO:0009743 183 0.011
positive regulation of ion transport GO:0043270 94 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
regulation of neuron death GO:1901214 115 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
positive regulation of kinase activity GO:0033674 77 0.010
anterior posterior pattern specification GO:0009952 1 0.010
immune system process GO:0002376 204 0.010
negative regulation of developmental process GO:0051093 125 0.010
heart morphogenesis GO:0003007 3 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
feeding behavior GO:0007631 53 0.010
regulation of growth GO:0040008 105 0.010
sex differentiation GO:0007548 113 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
response to toxic substance GO:0009636 133 0.010
salivary gland development GO:0007431 3 0.010
lipid storage GO:0019915 1 0.010
neuron projection morphogenesis GO:0048812 122 0.010
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.010

Abca8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.028
eye disease DOID:5614 0 0.028
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023
retinal disease DOID:5679 0 0.014
central nervous system disease DOID:331 0 0.013
disease of cellular proliferation DOID:14566 0 0.010