Rattus norvegicus

33 known processes

Ccr4

chemokine (C-C motif) receptor 4

(Aliases: Cmkbr4)

Ccr4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception GO:0007600 101 0.180
regulation of cell proliferation GO:0042127 359 0.151
Rat
forebrain development GO:0030900 98 0.122
Rat
locomotion GO:0040011 237 0.119
response to inorganic substance GO:0010035 377 0.112
positive regulation of response to stimulus GO:0048584 285 0.112
positive regulation of cell proliferation GO:0008284 249 0.104
Rat
inorganic cation transmembrane transport GO:0098662 202 0.102
cellular homeostasis GO:0019725 252 0.098
Rat
immune system process GO:0002376 204 0.097
Mouse Rat
regulation of secretion by cell GO:1903530 208 0.086
positive regulation of developmental process GO:0051094 283 0.084
Rat
response to bacterium GO:0009617 200 0.080
cation transmembrane transport GO:0098655 263 0.075
defense response GO:0006952 194 0.073
Mouse Rat
positive regulation of multicellular organismal process GO:0051240 387 0.070
Rat
apoptotic process GO:0006915 381 0.068
Rat
protein homotrimerization GO:0070207 15 0.066
transcription dna templated GO:0006351 377 0.065
multi multicellular organism process GO:0044706 138 0.064
monovalent inorganic cation transport GO:0015672 172 0.064
regulation of phosphorylation GO:0042325 248 0.063
Rat
positive regulation of gene expression GO:0010628 244 0.062
cation homeostasis GO:0055080 195 0.062
Rat
cellular chemical homeostasis GO:0055082 247 0.061
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.060
Mouse Rat
negative regulation of cell death GO:0060548 229 0.058
Rat
intracellular signal transduction GO:0035556 314 0.057
Rat
homeostatic process GO:0042592 331 0.057
Rat
brain development GO:0007420 247 0.056
Rat
response to molecule of bacterial origin GO:0002237 194 0.054
Rat
reproductive process GO:0022414 372 0.054
cellular metal ion homeostasis GO:0006875 172 0.053
Rat
nitrogen compound transport GO:0071705 229 0.052
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.052
signal transduction by phosphorylation GO:0023014 144 0.052
Rat
response to biotic stimulus GO:0009607 226 0.051
cation transport GO:0006812 382 0.051
Rat
transmembrane transport GO:0055085 412 0.050
response to other organism GO:0051707 220 0.050
head development GO:0060322 247 0.050
Rat
regulation of synaptic transmission GO:0050804 141 0.049
Rat
response to ammonium ion GO:0060359 71 0.049
regulation of behavior GO:0050795 61 0.048
ion transmembrane transport GO:0034220 365 0.048
programmed cell death GO:0012501 392 0.048
Rat
angiotensin mediated drinking behavior GO:0003051 2 0.048
response to wounding GO:0009611 254 0.047
Rat
negative regulation of developmental process GO:0051093 125 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
Rat
neuron differentiation GO:0030182 368 0.043
Rat
regulation of apoptotic process GO:0042981 335 0.043
Rat
rna metabolic process GO:0016070 406 0.042
taxis GO:0042330 67 0.042
positive regulation of protein phosphorylation GO:0001934 135 0.042
sensory perception of pain GO:0019233 73 0.042
regulation of anatomical structure morphogenesis GO:0022603 141 0.042
Rat
nucleic acid templated transcription GO:0097659 379 0.041
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.041
regulation of molecular function GO:0065009 398 0.041
multicellular organism reproduction GO:0032504 233 0.040
neurological system process GO:0050877 219 0.040
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.040
reproduction GO:0000003 245 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.040
regulation of chemotaxis GO:0050920 29 0.039
positive regulation of cellular component movement GO:0051272 102 0.039
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
immune response GO:0006955 104 0.039
Rat
regulation of cell development GO:0060284 263 0.038
Rat
multicellular organismal reproductive process GO:0048609 233 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.038
secretion GO:0046903 307 0.037
aging GO:0007568 241 0.037
cellular component assembly GO:0022607 360 0.037
inorganic ion transmembrane transport GO:0098660 229 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.036
Rat
regulation of epithelial cell proliferation GO:0050678 49 0.036
behavior GO:0007610 205 0.036
single organism biosynthetic process GO:0044711 342 0.036
chemical homeostasis GO:0048878 292 0.035
Rat
anatomical structure morphogenesis GO:0009653 298 0.035
Rat
cellular ion homeostasis GO:0006873 184 0.035
Rat
response to ketone GO:1901654 182 0.035
mapk cascade GO:0000165 140 0.035
Rat
positive regulation of biosynthetic process GO:0009891 319 0.035
smooth muscle contraction GO:0006939 37 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.034
micturition GO:0060073 4 0.033
growth GO:0040007 165 0.033
multicellular organismal response to stress GO:0033555 25 0.033
response to nutrient levels GO:0031667 370 0.033
response to external biotic stimulus GO:0043207 221 0.033
regulation of blood pressure GO:0008217 83 0.033
cellular response to abiotic stimulus GO:0071214 85 0.033
regulation of protein modification process GO:0031399 194 0.033
response to extracellular stimulus GO:0009991 380 0.032
response to acid chemical GO:0001101 222 0.032
response to lipopolysaccharide GO:0032496 191 0.032
Rat
metal ion transport GO:0030001 289 0.032
Rat
regulation of multicellular organismal development GO:2000026 376 0.031
Rat
protein phosphorylation GO:0006468 345 0.031
response to metal ion GO:0010038 253 0.031
muscle system process GO:0003012 115 0.031
Rat
phasic smooth muscle contraction GO:0014821 3 0.031
localization of cell GO:0051674 202 0.031
Mouse Rat
regulation of sensory perception of pain GO:0051930 29 0.030
rna biosynthetic process GO:0032774 380 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
Rat
negative regulation of signaling GO:0023057 157 0.030
response to radiation GO:0009314 137 0.030
negative regulation of multicellular organismal process GO:0051241 203 0.030
cellular cation homeostasis GO:0030003 180 0.030
Rat
positive regulation of secretion GO:0051047 140 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
positive regulation of locomotion GO:0040017 102 0.029
response to estradiol GO:0032355 164 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
positive regulation of cell death GO:0010942 184 0.028
Rat
positive regulation of rna metabolic process GO:0051254 203 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
Rat
regulation of muscle system process GO:0090257 79 0.028
response to decreased oxygen levels GO:0036293 237 0.027
Rat
negative regulation of chronic inflammatory response GO:0002677 2 0.027
Rat
renal system development GO:0072001 67 0.027
Rat
catecholamine secretion GO:0050432 33 0.027
positive regulation of secretion by cell GO:1903532 128 0.027
negative regulation of apoptotic process GO:0043066 181 0.027
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.026
regulation of system process GO:0044057 208 0.026
regulation of transcription dna templated GO:0006355 374 0.026
positive regulation of cell communication GO:0010647 271 0.026
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
cell chemotaxis GO:0060326 31 0.026
Rat
regulation of leukocyte migration GO:0002685 24 0.026
Rat
cell migration GO:0016477 197 0.025
Mouse Rat
amide transport GO:0042886 105 0.025
smooth muscle cell proliferation GO:0048659 77 0.025
response to toxic substance GO:0009636 133 0.025
negative regulation of cell communication GO:0010648 158 0.025
epithelial cell proliferation GO:0050673 54 0.025
sexual reproduction GO:0019953 148 0.025
erk1 and erk2 cascade GO:0070371 48 0.025
Rat
response to ethanol GO:0045471 162 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
positive regulation of transport GO:0051050 245 0.025
negative regulation of glutamate secretion GO:0014050 9 0.024
protein oligomerization GO:0051259 191 0.024
response to estrogen GO:0043627 232 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
positive regulation of catalytic activity GO:0043085 184 0.023
telencephalon development GO:0021537 62 0.023
Rat
positive regulation of protein metabolic process GO:0051247 178 0.023
response to oxidative stress GO:0006979 186 0.023
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.023
muscle cell proliferation GO:0033002 84 0.023
protein complex assembly GO:0006461 263 0.023
ossification GO:0001503 70 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
neuron death GO:0070997 127 0.022
metal ion homeostasis GO:0055065 186 0.022
Rat
negative regulation of secretion GO:0051048 82 0.022
regulation of protein metabolic process GO:0051246 289 0.022
regulation of programmed cell death GO:0043067 341 0.022
Rat
carboxylic acid metabolic process GO:0019752 289 0.021
regulation of neurogenesis GO:0050767 247 0.021
Rat
sensory perception of bitter taste GO:0050913 4 0.021
urinary tract smooth muscle contraction GO:0014848 4 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
response to reactive oxygen species GO:0000302 120 0.021
regulation of secretion GO:0051046 224 0.021
tissue development GO:0009888 252 0.021
Rat
single organism reproductive process GO:0044702 297 0.020
gamete generation GO:0007276 124 0.020
regulation of neurological system process GO:0031644 43 0.020
leukocyte activation GO:0045321 76 0.020
Rat
angiogenesis GO:0001525 53 0.020
Rat
negative regulation of secretion by cell GO:1903531 72 0.020
calcium ion homeostasis GO:0055074 162 0.020
Rat
protein homooligomerization GO:0051260 91 0.020
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.020
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.020
Rat
organ morphogenesis GO:0009887 75 0.020
amino acid transport GO:0006865 70 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
developmental process involved in reproduction GO:0003006 159 0.019
regulation of transferase activity GO:0051338 123 0.019
gonad development GO:0008406 104 0.019
cytokine production GO:0001816 61 0.019
Rat
regulation of ossification GO:0030278 32 0.019
regulation of catalytic activity GO:0050790 304 0.019
regulation of amine transport GO:0051952 54 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
regulation of signal transduction GO:0009966 318 0.019
Rat
cellular response to endogenous stimulus GO:0071495 377 0.019
Rat
male gonad development GO:0008584 59 0.018
macromolecule localization GO:0033036 252 0.018
regulation of rna metabolic process GO:0051252 391 0.018
regulation of metal ion transport GO:0010959 118 0.018
Rat
divalent metal ion transport GO:0070838 132 0.018
Rat
peristalsis GO:0030432 2 0.018
positive regulation of immune system process GO:0002684 90 0.018
Rat
regulation of cellular localization GO:0060341 263 0.018
cardiovascular system development GO:0072358 134 0.018
Rat
cell cell signaling GO:0007267 335 0.018
positive regulation of signal transduction GO:0009967 175 0.018
Rat
positive regulation of muscle contraction GO:0045933 22 0.018
regulation of immune system process GO:0002682 123 0.018
Rat
regulation of membrane potential GO:0042391 110 0.018
regulation of cell motility GO:2000145 131 0.017
Rat
positive regulation of transcription dna templated GO:0045893 197 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
Rat
multi organism reproductive process GO:0044703 262 0.017
detection of chemical stimulus GO:0009593 10 0.017
regulation of locomotion GO:0040012 148 0.017
regulation of kinase activity GO:0043549 117 0.017
positive regulation of leukocyte migration GO:0002687 21 0.017
Rat
inflammatory response GO:0006954 150 0.017
Mouse Rat
cellular amine metabolic process GO:0044106 38 0.017
nucleoside metabolic process GO:0009116 179 0.017
regulation of cell differentiation GO:0045595 320 0.017
Rat
positive regulation of protein modification process GO:0031401 142 0.017
positive regulation of cell development GO:0010720 176 0.017
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.016
central nervous system development GO:0007417 311 0.016
Rat
metanephric tubule morphogenesis GO:0072173 2 0.016
Rat
positive regulation of ion transport GO:0043270 94 0.016
organic acid metabolic process GO:0006082 292 0.016
response to growth factor GO:0070848 189 0.016
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
Rat
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
circulatory system process GO:0003013 183 0.016
Rat
vascular process in circulatory system GO:0003018 96 0.016
Rat
nucleotide metabolic process GO:0009117 279 0.016
positive regulation of nervous system development GO:0051962 178 0.016
Rat
negative regulation of response to stimulus GO:0048585 155 0.016
Rat
negative regulation of transport GO:0051051 136 0.016
muscle contraction GO:0006936 88 0.015
Rat
negative regulation of programmed cell death GO:0043069 183 0.015
Rat
regulation of sensory perception GO:0051931 29 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
Rat
renal sodium excretion GO:0035812 20 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
gland development GO:0048732 155 0.015
negative regulation of lyase activity GO:0051350 8 0.015
regulation of neuron death GO:1901214 115 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
Rat
rhythmic process GO:0048511 156 0.015
angioblast cell migration GO:0035476 1 0.015
Rat
regulation of blood vessel size GO:0050880 89 0.015
single organism intracellular transport GO:1902582 166 0.015
sodium ion transport GO:0006814 82 0.015
regulation of mapk cascade GO:0043408 116 0.015
Rat
negative regulation of cyclic nucleotide metabolic process GO:0030800 15 0.014
eosinophil chemotaxis GO:0048245 3 0.014
Rat
developmental induction GO:0031128 2 0.014
cellular response to external stimulus GO:0071496 118 0.014
peptide transport GO:0015833 97 0.014
cell fate determination GO:0001709 2 0.014
negative regulation of molecular function GO:0044092 133 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
Rat
regulation of tube size GO:0035150 89 0.014
macromolecular complex assembly GO:0065003 273 0.014
positive regulation of response to external stimulus GO:0032103 51 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
oxoacid metabolic process GO:0043436 290 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
Rat
response to testosterone GO:0033574 55 0.014
detection of stimulus GO:0051606 24 0.014
positive regulation of synaptic transmission gabaergic GO:0032230 9 0.014
negative regulation of long term synaptic potentiation GO:1900272 1 0.014
Rat
chemotaxis GO:0006935 66 0.013
regulation of hormone levels GO:0010817 187 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
urinary bladder smooth muscle contraction GO:0014832 4 0.013
innate immune response GO:0045087 35 0.013
cellular component biogenesis GO:0044085 368 0.013
learning or memory GO:0007611 90 0.013
Rat
lung development GO:0030324 43 0.013
negative regulation of camp biosynthetic process GO:0030818 12 0.013
amine metabolic process GO:0009308 38 0.013
positive regulation of molecular function GO:0044093 230 0.013
female pregnancy GO:0007565 122 0.013
actin filament organization GO:0007015 42 0.013
negative regulation of chronic inflammatory response to non antigenic stimulus GO:0002881 1 0.013
Rat
heart process GO:0003015 57 0.013
Rat
positive regulation of homeostatic process GO:0032846 49 0.013
cell cycle GO:0007049 101 0.012
sex differentiation GO:0007548 113 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
cytoskeleton organization GO:0007010 111 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
reproductive structure development GO:0048608 128 0.012
regulation of cell cycle GO:0051726 73 0.012
positive regulation of signaling GO:0023056 270 0.012
Rat
response to fatty acid GO:0070542 65 0.012
saliva secretion GO:0046541 3 0.012
regulation of muscle contraction GO:0006937 53 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
synaptic transmission GO:0007268 235 0.012
cell type specific apoptotic process GO:0097285 134 0.012
Rat
negative regulation of gene expression GO:0010629 199 0.012
negative regulation of signal transduction GO:0009968 83 0.012
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.012
carboxylic acid transport GO:0046942 115 0.012
response to hypoxia GO:0001666 231 0.012
Rat
negative regulation of amine transport GO:0051953 24 0.012
hormone metabolic process GO:0042445 69 0.012
organic hydroxy compound transport GO:0015850 77 0.012
negative regulation of ion transport GO:0043271 51 0.012
organelle organization GO:0006996 266 0.012
response to mechanical stimulus GO:0009612 134 0.012
organophosphate metabolic process GO:0019637 370 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cytoplasmic transport GO:0016482 115 0.011
anion transport GO:0006820 178 0.011
ion homeostasis GO:0050801 212 0.011
Rat
negative regulation of catalytic activity GO:0043086 103 0.011
catecholamine transport GO:0051937 37 0.011
regulation of ion transport GO:0043269 245 0.011
Rat
nucleoside monophosphate metabolic process GO:0009123 93 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
cell motility GO:0048870 202 0.011
Mouse Rat
cell adhesion GO:0007155 110 0.011
regulation of ion homeostasis GO:2000021 63 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
Rat
secretion by cell GO:0032940 248 0.011
cellular response to drug GO:0035690 30 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
detection of chemical stimulus involved in sensory perception of taste GO:0050912 6 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
Rat
metanephric tubule development GO:0072170 4 0.011
Rat
drinking behavior GO:0042756 11 0.011
response to alkaloid GO:0043279 132 0.011
response to glucocorticoid GO:0051384 223 0.011
myeloid leukocyte activation GO:0002274 36 0.010
Rat
response to peptide GO:1901652 292 0.010
purine containing compound metabolic process GO:0072521 253 0.010
regulation of growth GO:0040008 105 0.010
positive regulation of epithelial cell proliferation GO:0050679 32 0.010
response to corticosteroid GO:0031960 235 0.010
cellular response to estradiol stimulus GO:0071392 16 0.010
single organism behavior GO:0044708 130 0.010
Rat
kidney development GO:0001822 67 0.010
Rat
negative regulation of metabolic process GO:0009892 331 0.010
epithelial cell migration GO:0010631 19 0.010
limbic system development GO:0021761 38 0.010

Ccr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.011