Rattus norvegicus

0 known processes

Prickle2

prickle homolog 2 (Drosophila)

Prickle2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.102
regulation of molecular function GO:0065009 398 0.087
cellular component biogenesis GO:0044085 368 0.073
regulation of phosphate metabolic process GO:0019220 349 0.066
regulation of programmed cell death GO:0043067 341 0.064
cellular component assembly GO:0022607 360 0.064
positive regulation of signaling GO:0023056 270 0.064
central nervous system development GO:0007417 311 0.052
intracellular signal transduction GO:0035556 314 0.051
regulation of apoptotic process GO:0042981 335 0.049
organophosphate metabolic process GO:0019637 370 0.048
response to growth factor GO:0070848 189 0.047
head development GO:0060322 247 0.046
positive regulation of phosphate metabolic process GO:0045937 262 0.045
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.044
protein complex assembly GO:0006461 263 0.043
catabolic process GO:0009056 351 0.041
regulation of cellular component movement GO:0051270 150 0.040
protein phosphorylation GO:0006468 345 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.039
lipid metabolic process GO:0006629 283 0.039
cellular response to oxygen containing compound GO:1901701 386 0.038
macromolecule localization GO:0033036 252 0.036
Rat
protein complex biogenesis GO:0070271 263 0.036
apoptotic process GO:0006915 381 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.035
localization of cell GO:0051674 202 0.035
protein localization GO:0008104 191 0.035
Rat
macromolecular complex assembly GO:0065003 273 0.035
cellular component movement GO:0006928 248 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
regulation of signal transduction GO:0009966 318 0.033
regulation of canonical wnt signaling pathway GO:0060828 4 0.033
positive regulation of developmental process GO:0051094 283 0.033
cell motility GO:0048870 202 0.033
negative regulation of metabolic process GO:0009892 331 0.033
response to peptide hormone GO:0043434 278 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
positive regulation of catalytic activity GO:0043085 184 0.032
single organism catabolic process GO:0044712 283 0.032
locomotion GO:0040011 237 0.032
cellular lipid metabolic process GO:0044255 208 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
regulation of phosphorylation GO:0042325 248 0.031
regulation of catalytic activity GO:0050790 304 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
brain development GO:0007420 247 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
protein complex subunit organization GO:0071822 302 0.030
positive regulation of phosphorylation GO:0042327 177 0.030
cellular response to stress GO:0033554 269 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
positive regulation of cell communication GO:0010647 271 0.030
organelle organization GO:0006996 266 0.030
regulation of multicellular organismal development GO:2000026 376 0.029
transcription dna templated GO:0006351 377 0.029
purine containing compound catabolic process GO:0072523 138 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
glycosyl compound metabolic process GO:1901657 182 0.027
positive regulation of nucleoside metabolic process GO:0045979 55 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
regulation of cellular component organization GO:0051128 368 0.026
positive regulation of cellular component movement GO:0051272 102 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
negative regulation of nervous system development GO:0051961 79 0.024
positive regulation of molecular function GO:0044093 230 0.024
regulation of protein modification process GO:0031399 194 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
response to wounding GO:0009611 254 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
regulation of cell motility GO:2000145 131 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of protein metabolic process GO:0051246 289 0.023
regulation of neuron death GO:1901214 115 0.022
organic acid metabolic process GO:0006082 292 0.022
regulation of rna metabolic process GO:0051252 391 0.022
cell type specific apoptotic process GO:0097285 134 0.022
defense response GO:0006952 194 0.022
cation homeostasis GO:0055080 195 0.022
organophosphate catabolic process GO:0046434 148 0.022
positive regulation of cell motility GO:2000147 97 0.021
regulation of cell differentiation GO:0045595 320 0.021
cellular homeostasis GO:0019725 252 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
ribonucleoside triphosphate metabolic process GO:0009199 141 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
phospholipid metabolic process GO:0006644 61 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
chemical homeostasis GO:0048878 292 0.020
response to organophosphorus GO:0046683 102 0.020
response to cytokine GO:0034097 215 0.020
carbohydrate metabolic process GO:0005975 130 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
amine metabolic process GO:0009308 38 0.020
single organism organelle organization GO:1902589 180 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
rna biosynthetic process GO:0032774 380 0.020
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
response to nutrient levels GO:0031667 370 0.019
regulation of cellular component biogenesis GO:0044087 86 0.019
positive regulation of locomotion GO:0040017 102 0.019
regulation of hydrolase activity GO:0051336 143 0.019
calcium ion homeostasis GO:0055074 162 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.018
regulation of transcription dna templated GO:0006355 374 0.018
positive regulation of cell death GO:0010942 184 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
gtp metabolic process GO:0046039 72 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
cellular protein localization GO:0034613 122 0.018
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.018
ras protein signal transduction GO:0007265 29 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
negative regulation of cell death GO:0060548 229 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
response to other organism GO:0051707 220 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
mapk cascade GO:0000165 140 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
regulation of mapk cascade GO:0043408 116 0.017
neuron development GO:0048666 286 0.017
Fly
cell cell signaling GO:0007267 335 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
negative regulation of cellular component organization GO:0051129 83 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
response to acid chemical GO:0001101 222 0.017
response to camp GO:0051591 91 0.017
regulation of cellular response to stress GO:0080135 49 0.016
positive regulation of cell development GO:0010720 176 0.016
negative regulation of cell communication GO:0010648 158 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
single organism cellular localization GO:1902580 102 0.016
Rat
regulation of cell development GO:0060284 263 0.016
response to bacterium GO:0009617 200 0.016
neurological system process GO:0050877 219 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
cation transport GO:0006812 382 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
response to metal ion GO:0010038 253 0.016
single organism intracellular transport GO:1902582 166 0.016
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
response to external biotic stimulus GO:0043207 221 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
synaptic transmission GO:0007268 235 0.016
glycerophospholipid metabolic process GO:0006650 47 0.016
intracellular transport GO:0046907 185 0.015
Rat
cellular response to peptide GO:1901653 133 0.015
reproductive process GO:0022414 372 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
organic substance catabolic process GO:1901575 316 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
central nervous system neuron axonogenesis GO:0021955 1 0.015
positive regulation of cell migration GO:0030335 96 0.015
establishment of protein localization GO:0045184 141 0.015
Rat
response to inorganic substance GO:0010035 377 0.015
regulation of response to stress GO:0080134 126 0.015
cellular chemical homeostasis GO:0055082 247 0.015
regulation of gtp catabolic process GO:0033124 58 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
single organism membrane organization GO:0044802 74 0.015
regulation of locomotion GO:0040012 148 0.015
cellular cation homeostasis GO:0030003 180 0.015
ion homeostasis GO:0050801 212 0.015
regulation of catabolic process GO:0009894 113 0.015
negative regulation of signaling GO:0023057 157 0.015
actin filament based process GO:0030029 86 0.014
homeostatic process GO:0042592 331 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of nervous system development GO:0051960 264 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
purine containing compound metabolic process GO:0072521 253 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
negative regulation of gene expression GO:0010629 199 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
neuron projection development GO:0031175 273 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
eye morphogenesis GO:0048592 4 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
cell projection organization GO:0030030 302 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
multi organism reproductive process GO:0044703 262 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
cellular ion homeostasis GO:0006873 184 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
neuron differentiation GO:0030182 368 0.013
Fly
purine ribonucleoside metabolic process GO:0046128 168 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
negative regulation of developmental process GO:0051093 125 0.013
response to extracellular stimulus GO:0009991 380 0.013
regulation of nucleotide catabolic process GO:0030811 65 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
cellular component maintenance GO:0043954 4 0.013
response to monosaccharide GO:0034284 159 0.013
regulation of cell proliferation GO:0042127 359 0.013
nucleotide catabolic process GO:0009166 139 0.013
single organism biosynthetic process GO:0044711 342 0.013
protein oligomerization GO:0051259 191 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
neuron apoptotic process GO:0051402 88 0.013
dna metabolic process GO:0006259 96 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
response to glucocorticoid GO:0051384 223 0.013
nucleic acid templated transcription GO:0097659 379 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
negative regulation of biosynthetic process GO:0009890 168 0.012
response to carbohydrate GO:0009743 183 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
gtp catabolic process GO:0006184 71 0.012
cell projection morphogenesis GO:0048858 123 0.012
mitotic spindle organization GO:0007052 2 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
regulation of hormone levels GO:0010817 187 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
rho protein signal transduction GO:0007266 11 0.012
response to reactive oxygen species GO:0000302 120 0.012
salivary gland development GO:0007431 3 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
actin cytoskeleton organization GO:0030036 73 0.012
regulation of response to external stimulus GO:0032101 106 0.012
metal ion homeostasis GO:0055065 186 0.012
phasic smooth muscle contraction GO:0014821 3 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
dendrite development GO:0016358 72 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
response to corticosteroid GO:0031960 235 0.012
heterocycle catabolic process GO:0046700 167 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
positive regulation of transferase activity GO:0051347 81 0.012
cellular response to lipid GO:0071396 201 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
salivary gland morphogenesis GO:0007435 1 0.012
inflammatory response GO:0006954 150 0.012
regulation of transferase activity GO:0051338 123 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
proteolysis GO:0006508 175 0.012
oxoacid metabolic process GO:0043436 290 0.012
axis specification GO:0009798 4 0.011
spermatogenesis GO:0007283 99 0.011
neuron death GO:0070997 127 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
response to lipopolysaccharide GO:0032496 191 0.011
synapse organization GO:0050808 46 0.011
regulation of cell projection organization GO:0031344 175 0.011
single organism reproductive process GO:0044702 297 0.011
positive regulation of gene expression GO:0010628 244 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
regulation of kinase activity GO:0043549 117 0.011
response to peptide GO:1901652 292 0.011
response to ethanol GO:0045471 162 0.011
developmental process involved in reproduction GO:0003006 159 0.011
regulation of gtpase activity GO:0043087 57 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
secretion by cell GO:0032940 248 0.011
reproduction GO:0000003 245 0.011
protein homooligomerization GO:0051260 91 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
negative regulation of viral process GO:0048525 4 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
negative regulation of innate immune response GO:0045824 4 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
dendrite morphogenesis GO:0048813 43 0.011
gamete generation GO:0007276 124 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
cell migration GO:0016477 197 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
regulation of cell migration GO:0030334 128 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
response to estradiol GO:0032355 164 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
regulation of response to wounding GO:1903034 69 0.010
immune system process GO:0002376 204 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
cytoplasmic transport GO:0016482 115 0.010
Rat
multicellular organism growth GO:0035264 1 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
secretion GO:0046903 307 0.010
cellular amino acid metabolic process GO:0006520 107 0.010

Prickle2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
Human
nervous system disease DOID:863 0 0.037
Human
central nervous system disease DOID:331 0 0.026
Human
brain disease DOID:936 0 0.017
Human
muscular disease DOID:0080000 0 0.011
musculoskeletal system disease DOID:17 0 0.011
myopathy DOID:423 0 0.010
muscular dystrophy DOID:9884 0 0.010
muscle tissue disease DOID:66 0 0.010