Rattus norvegicus

95 known processes

Nlgn3

neuroligin 3

Nlgn3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.634
synaptic transmission GO:0007268 235 0.530
learning or memory GO:0007611 90 0.515
Human Mouse
synapse organization GO:0050808 46 0.496
cognition GO:0050890 92 0.475
Human Mouse
locomotion GO:0040011 237 0.444
Rat
positive regulation of signaling GO:0023056 270 0.432
Mouse Rat
regulation of synaptic transmission GO:0050804 141 0.421
response to mechanical stimulus GO:0009612 134 0.411
regulation of multicellular organismal development GO:2000026 376 0.314
positive regulation of cell communication GO:0010647 271 0.280
Mouse Rat
neurotransmitter transport GO:0006836 42 0.279
Rat
positive regulation of transport GO:0051050 245 0.270
Mouse Rat
cellular protein localization GO:0034613 122 0.268
Rat
positive regulation of synaptic transmission GO:0050806 62 0.266
Mouse Rat
positive regulation of signal transduction GO:0009967 175 0.253
Mouse Rat
protein localization GO:0008104 191 0.245
Rat
regulation of neurotransmitter levels GO:0001505 42 0.243
Rat
cellular component biogenesis GO:0044085 368 0.211
regulation of ion transport GO:0043269 245 0.193
Mouse Rat
regulation of cellular localization GO:0060341 263 0.192
Rat
asymmetric protein localization GO:0008105 2 0.191
protein localization to membrane GO:0072657 36 0.187
Rat
immune system process GO:0002376 204 0.185
neuron development GO:0048666 286 0.184
neuron neuron synaptic transmission GO:0007270 60 0.181
Mouse Rat Fly
gamma aminobutyric acid secretion GO:0014051 6 0.176
synaptic vesicle endocytosis GO:0048488 4 0.167
Rat
regulation of vesicle mediated transport GO:0060627 81 0.164
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.163
positive regulation of intracellular signal transduction GO:1902533 138 0.162
Rat
cellular macromolecule localization GO:0070727 122 0.159
Rat
positive regulation of membrane potential GO:0045838 16 0.154
Mouse Rat
neurotransmitter secretion GO:0007269 33 0.152
Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.151
regulation of cellular component organization GO:0051128 368 0.147
regulation of neurotransmitter secretion GO:0046928 19 0.147
Rat
carboxylic acid transport GO:0046942 115 0.144
anion transport GO:0006820 178 0.143
regulation of secretion by cell GO:1903530 208 0.133
Rat
response to nicotine GO:0035094 51 0.132
neurological system process GO:0050877 219 0.127
Human Mouse
regulation of protein phosphorylation GO:0001932 183 0.126
positive regulation of cell differentiation GO:0045597 217 0.125
Rat
circulatory system process GO:0003013 183 0.124
regulation of system process GO:0044057 208 0.123
Mouse
cellular ion homeostasis GO:0006873 184 0.122
single organism behavior GO:0044708 130 0.122
Human Mouse Rat Fly
vascular process in circulatory system GO:0003018 96 0.117
synaptic transmission gabaergic GO:0051932 22 0.115
Rat Fly
macromolecule localization GO:0033036 252 0.111
Rat
response to alkaloid GO:0043279 132 0.110
nucleobase containing small molecule metabolic process GO:0055086 316 0.108
regulation of blood vessel size GO:0050880 89 0.106
regulation of postsynaptic membrane potential GO:0060078 25 0.104
nitrogen compound transport GO:0071705 229 0.103
g protein coupled acetylcholine receptor signaling pathway GO:0007213 5 0.101
acid secretion GO:0046717 48 0.099
cellular response to organic cyclic compound GO:0071407 202 0.098
neuron differentiation GO:0030182 368 0.096
regulation of intracellular signal transduction GO:1902531 218 0.094
Rat
positive regulation of developmental process GO:0051094 283 0.092
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.092
negative regulation of cell communication GO:0010648 158 0.088
protein transport GO:0015031 132 0.086
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.085
regulation of synaptic plasticity GO:0048167 70 0.084
Mouse
multicellular organism growth GO:0035264 1 0.083
regulation of anatomical structure morphogenesis GO:0022603 141 0.083
Mouse
gamma aminobutyric acid transport GO:0015812 8 0.083
behavior GO:0007610 205 0.082
Human Mouse Rat Fly
regulation of muscle system process GO:0090257 79 0.080
regulation of anatomical structure size GO:0090066 135 0.079
synaptic vesicle exocytosis GO:0016079 15 0.077
Rat
positive regulation of cell development GO:0010720 176 0.076
Rat
brain development GO:0007420 247 0.076
sensory perception GO:0007600 101 0.076
carbohydrate derivative metabolic process GO:1901135 346 0.076
regulation of locomotion GO:0040012 148 0.075
regulation of membrane potential GO:0042391 110 0.074
mapk cascade GO:0000165 140 0.074
cellular component movement GO:0006928 248 0.074
cellular component assembly GO:0022607 360 0.072
synaptic growth at neuromuscular junction GO:0051124 1 0.071
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.069
regulation of cell differentiation GO:0045595 320 0.067
Mouse Rat
secretion by cell GO:0032940 248 0.067
Rat
regulation of mapk cascade GO:0043408 116 0.067
response to metal ion GO:0010038 253 0.066
cellular divalent inorganic cation homeostasis GO:0072503 162 0.066
receptor localization to synapse GO:0097120 2 0.066
membrane organization GO:0061024 94 0.066
positive regulation of synaptic vesicle endocytosis GO:1900244 1 0.065
Rat
cellular chemical homeostasis GO:0055082 247 0.064
rhythmic process GO:0048511 156 0.064
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.063
Mouse Rat
dicarboxylic acid transport GO:0006835 34 0.062
cell projection organization GO:0030030 302 0.062
positive regulation of nervous system development GO:0051962 178 0.061
regulation of cell migration GO:0030334 128 0.061
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.061
learning GO:0007612 33 0.061
Human Mouse
amino acid transport GO:0006865 70 0.061
positive regulation of cellular component organization GO:0051130 200 0.060
sodium ion transport GO:0006814 82 0.060
cellular response to stress GO:0033554 269 0.058
cellular response to cytokine stimulus GO:0071345 127 0.057
rhythmic synaptic transmission GO:0060024 1 0.056
positive regulation of ion transport GO:0043270 94 0.056
Mouse
negative regulation of signaling GO:0023057 157 0.055
vesicle mediated transport GO:0016192 181 0.055
signal release GO:0023061 145 0.055
Rat
positive regulation of cell projection organization GO:0031346 111 0.054
Rat
negative regulation of cell proliferation GO:0008285 119 0.054
response to inorganic substance GO:0010035 377 0.053
regulation of phosphate metabolic process GO:0019220 349 0.053
protein autophosphorylation GO:0046777 66 0.053
regulation of synaptic transmission glutamatergic GO:0051966 26 0.053
Mouse Rat
cellular amine metabolic process GO:0044106 38 0.053
cellular amino acid metabolic process GO:0006520 107 0.053
positive regulation of neuron projection development GO:0010976 99 0.052
Rat
regulation of synapse assembly GO:0051963 15 0.052
metal ion homeostasis GO:0055065 186 0.052
organic anion transport GO:0015711 132 0.051
single organism membrane organization GO:0044802 74 0.051
amine metabolic process GO:0009308 38 0.051
regulation of synaptic transmission gabaergic GO:0032228 17 0.051
Rat
locomotory behavior GO:0007626 15 0.051
Rat Fly
ion homeostasis GO:0050801 212 0.050
synaptic transmission glutamatergic GO:0035249 33 0.050
Mouse Rat
cellular homeostasis GO:0019725 252 0.049
reproductive process GO:0022414 372 0.049
Fly
positive regulation of phosphorus metabolic process GO:0010562 262 0.048
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.048
neuron projection development GO:0031175 273 0.047
regulation of axonogenesis GO:0050770 37 0.047
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.047
Mouse Rat
response to cytokine GO:0034097 215 0.046
sensory perception of pain GO:0019233 73 0.046
single organism cellular localization GO:1902580 102 0.045
Rat
cellular response to lipid GO:0071396 201 0.045
regulation of endocytosis GO:0030100 42 0.045
Rat
regulation of blood circulation GO:1903522 110 0.045
heart process GO:0003015 57 0.044
cell part morphogenesis GO:0032990 123 0.044
regulation of tube size GO:0035150 89 0.044
negative regulation of ion transport GO:0043271 51 0.043
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.043
response to mineralocorticoid GO:0051385 49 0.043
regulation of nervous system development GO:0051960 264 0.043
protein oligomerization GO:0051259 191 0.043
Rat
cation transport GO:0006812 382 0.042
nucleotide catabolic process GO:0009166 139 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.042
intracellular transport GO:0046907 185 0.042
Rat
calcium ion homeostasis GO:0055074 162 0.041
organelle organization GO:0006996 266 0.041
Rat
positive regulation of response to stimulus GO:0048584 285 0.041
Mouse Rat
blood circulation GO:0008015 183 0.041
monovalent inorganic cation transport GO:0015672 172 0.041
biological adhesion GO:0022610 110 0.041
response to tumor necrosis factor GO:0034612 56 0.040
smooth muscle contraction GO:0006939 37 0.040
negative regulation of response to stimulus GO:0048585 155 0.040
intracellular signal transduction GO:0035556 314 0.040
Rat
inflammatory response GO:0006954 150 0.040
response to radiation GO:0009314 137 0.039
Mouse
purine containing compound metabolic process GO:0072521 253 0.039
transcription dna templated GO:0006351 377 0.039
response to cgmp GO:0070305 3 0.039
organophosphate metabolic process GO:0019637 370 0.039
metal ion transport GO:0030001 289 0.039
glutamate secretion GO:0014047 19 0.038
positive regulation of phosphorylation GO:0042327 177 0.038
secretion GO:0046903 307 0.038
Rat
regulation of secretion GO:0051046 224 0.038
Rat
developmental process involved in reproduction GO:0003006 159 0.037
organic acid transport GO:0015849 116 0.037
l glutamate import GO:0051938 2 0.037
regulation of neuron differentiation GO:0045664 208 0.037
Mouse Rat
synapse assembly GO:0007416 29 0.036
somatic stem cell division GO:0048103 2 0.036
response to oxygen levels GO:0070482 265 0.036
enzyme linked receptor protein signaling pathway GO:0007167 116 0.036
defense response GO:0006952 194 0.036
negative regulation of signal transduction GO:0009968 83 0.036
response to oxidative stress GO:0006979 186 0.035
response to corticosteroid GO:0031960 235 0.035
positive regulation of cellular protein metabolic process GO:0032270 167 0.035
cell type specific apoptotic process GO:0097285 134 0.035
regulation of cellular amine metabolic process GO:0033238 8 0.035
transmembrane transport GO:0055085 412 0.035
Mouse Rat
ribonucleotide metabolic process GO:0009259 231 0.034
establishment of protein localization GO:0045184 141 0.034
Rat
associative learning GO:0008306 19 0.034
Mouse
regulation of behavior GO:0050795 61 0.034
ossification GO:0001503 70 0.034
regulation of potassium ion transport GO:0043266 29 0.033
positive regulation of secretion GO:0051047 140 0.033
Rat
organophosphate catabolic process GO:0046434 148 0.033
protein phosphorylation GO:0006468 345 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
head development GO:0060322 247 0.033
response to hypoxia GO:0001666 231 0.032
positive regulation of cellular amine metabolic process GO:0033240 3 0.032
chemical homeostasis GO:0048878 292 0.032
regulation of ion transmembrane transporter activity GO:0032412 48 0.032
Mouse Rat
purine nucleoside metabolic process GO:0042278 169 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
positive regulation of molecular function GO:0044093 230 0.032
Mouse
gonad development GO:0008406 104 0.031
regulation of neuron apoptotic process GO:0043523 83 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
negative regulation of transport GO:0051051 136 0.031
regulation of signal transduction GO:0009966 318 0.031
Mouse Rat
regulation of immune system process GO:0002682 123 0.031
cell morphogenesis GO:0000902 142 0.031
rna biosynthetic process GO:0032774 380 0.031
serotonin metabolic process GO:0042428 3 0.031
membrane hyperpolarization GO:0060081 11 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.030
Mouse
response to ketone GO:1901654 182 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.030
positive regulation of gamma aminobutyric acid secretion GO:0014054 4 0.029
apoptotic process GO:0006915 381 0.029
positive regulation of camp metabolic process GO:0030816 31 0.029
regulation of neurotransmitter transport GO:0051588 21 0.029
Rat
anatomical structure morphogenesis GO:0009653 298 0.029
cellular cation homeostasis GO:0030003 180 0.029
hematopoietic progenitor cell differentiation GO:0002244 2 0.029
regulation of rna metabolic process GO:0051252 391 0.029
regulation of heart contraction GO:0008016 48 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
rna metabolic process GO:0016070 406 0.029
cation transmembrane transport GO:0098655 263 0.028
monocarboxylic acid transport GO:0015718 52 0.028
detection of external stimulus GO:0009581 13 0.028
regulation of cell motility GO:2000145 131 0.028
mechanoreceptor differentiation GO:0042490 2 0.028
monoamine transport GO:0015844 43 0.028
regulation of cell morphogenesis GO:0022604 77 0.028
Mouse
multicellular organismal reproductive process GO:0048609 233 0.028
Fly
regulation of vascular smooth muscle contraction GO:0003056 3 0.027
aging GO:0007568 241 0.027
plasma membrane organization GO:0007009 17 0.027
cellular response to nicotine GO:0071316 7 0.027
neuron projection morphogenesis GO:0048812 122 0.027
response to osmotic stress GO:0006970 42 0.027
regulation of neurogenesis GO:0050767 247 0.026
Mouse Rat
multicellular organism reproduction GO:0032504 233 0.026
Fly
response to nutrient levels GO:0031667 370 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.026
neuron apoptotic process GO:0051402 88 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
regulation of kinase activity GO:0043549 117 0.026
reproduction GO:0000003 245 0.025
Fly
regulation of synapse organization GO:0050807 19 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.025
glutamate receptor signaling pathway GO:0007215 43 0.025
Mouse Rat
regulation of protein metabolic process GO:0051246 289 0.025
nucleoside metabolic process GO:0009116 179 0.025
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.025
Mouse
memory GO:0007613 54 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
central nervous system development GO:0007417 311 0.025
Mouse
cellular response to abiotic stimulus GO:0071214 85 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
muscle system process GO:0003012 115 0.024
response to growth factor GO:0070848 189 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
positive regulation of neurotransmitter secretion GO:0001956 9 0.024
Rat
neurotransmitter uptake GO:0001504 3 0.024
regulation of cell projection organization GO:0031344 175 0.024
Mouse Rat
response to histamine GO:0034776 3 0.024
protein complex assembly GO:0006461 263 0.024
Rat
olfactory learning GO:0008355 1 0.024
homeostatic process GO:0042592 331 0.024
central nervous system neuron development GO:0021954 5 0.024
thigmotaxis GO:0001966 1 0.024
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
Rat
positive regulation of synapse assembly GO:0051965 12 0.023
response to ethanol GO:0045471 162 0.023
response to estradiol GO:0032355 164 0.023
cellular response to cgmp GO:0071321 2 0.023
regulation of neuron projection development GO:0010975 161 0.023
Mouse Rat
positive regulation of synaptic transmission gabaergic GO:0032230 9 0.023
Rat
auditory receptor cell differentiation GO:0042491 2 0.023
central nervous system neuron axonogenesis GO:0021955 1 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
erk1 and erk2 cascade GO:0070371 48 0.022
positive regulation of mapk cascade GO:0043410 92 0.022
regulation of cell development GO:0060284 263 0.022
Mouse Rat
regulation of erk1 and erk2 cascade GO:0070372 41 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
regulation of sodium ion transport GO:0002028 21 0.022
potassium ion transport GO:0006813 97 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
long term synaptic potentiation GO:0060291 21 0.022
Mouse
regulation of neuronal synaptic plasticity GO:0048168 31 0.022
respiratory gaseous exchange GO:0007585 4 0.022
Mouse
synaptic transmission cholinergic GO:0007271 11 0.022
protein complex subunit organization GO:0071822 302 0.021
Rat
nucleic acid templated transcription GO:0097659 379 0.021
response to cocaine GO:0042220 39 0.021
regulation of cell proliferation GO:0042127 359 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
camp metabolic process GO:0046058 63 0.021
action potential GO:0001508 54 0.021
peptidyl amino acid modification GO:0018193 126 0.021
embryonic pattern specification GO:0009880 1 0.021
regulation of response to stress GO:0080134 126 0.021
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.021
protein targeting GO:0006605 61 0.021
Rat
amine transport GO:0015837 57 0.021
glycerolipid metabolic process GO:0046486 67 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
response to glucocorticoid GO:0051384 223 0.020
regulation of anion transport GO:0044070 43 0.020
regulation of homeostatic process GO:0032844 101 0.020
adult locomotory behavior GO:0008344 4 0.020
Rat Fly
calcium mediated signaling GO:0019722 23 0.020
response to decreased oxygen levels GO:0036293 237 0.020
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.020
positive regulation of immune system process GO:0002684 90 0.020
asymmetric stem cell division GO:0098722 2 0.020
salivary gland development GO:0007431 3 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.020
axis specification GO:0009798 4 0.020
regulation of protein serine threonine kinase activity GO:0071900 64 0.020
retinal ganglion cell axon guidance GO:0031290 1 0.020
macromolecular complex assembly GO:0065003 273 0.020
Rat
response to amino acid GO:0043200 75 0.020
cellular nitrogen compound catabolic process GO:0044270 163 0.019
synaptic vesicle recycling GO:0036465 5 0.019
Rat
localization of cell GO:0051674 202 0.019
regeneration GO:0031099 163 0.019
locomotor rhythm GO:0045475 1 0.019
second messenger mediated signaling GO:0019932 51 0.019
oxoacid metabolic process GO:0043436 290 0.019
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.019
regulation of neuron death GO:1901214 115 0.019
optic nerve development GO:0021554 3 0.019
divalent inorganic cation transport GO:0072511 134 0.019
dorsal ventral axon guidance GO:0033563 1 0.019
response to retinoic acid GO:0032526 63 0.019
regulation of protein modification process GO:0031399 194 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
positive regulation of nucleotide metabolic process GO:0045981 91 0.019
regulation of ion transmembrane transport GO:0034765 121 0.018
Mouse Rat
regulation of transporter activity GO:0032409 50 0.018
Mouse Rat
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 5 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
Rat
olfactory behavior GO:0042048 2 0.018
negative regulation of secretion GO:0051048 82 0.018
regulation of cellular component movement GO:0051270 150 0.018
ribonucleotide catabolic process GO:0009261 136 0.017
regulation of meiotic cell cycle GO:0051445 3 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
dephosphorylation GO:0016311 98 0.017
ribose phosphate biosynthetic process GO:0046390 87 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
cellular component morphogenesis GO:0032989 155 0.017
cell motility GO:0048870 202 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.017
regulation of stress activated mapk cascade GO:0032872 23 0.017
regulation of protein localization GO:0032880 81 0.017
nucleotide metabolic process GO:0009117 279 0.017
sensory perception of temperature stimulus GO:0050951 5 0.017
cell projection morphogenesis GO:0048858 123 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
response to hexose GO:0009746 144 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.017
positive regulation of intracellular protein transport GO:0090316 20 0.016
nucleoside catabolic process GO:0009164 126 0.016
cellular component maintenance GO:0043954 4 0.016
Fly
positive regulation of long term synaptic potentiation GO:1900273 4 0.016
negative regulation of circadian sleep wake cycle sleep GO:0042321 5 0.016
gliogenesis GO:0042063 93 0.016
Mouse
organic acid metabolic process GO:0006082 292 0.016
ras protein signal transduction GO:0007265 29 0.016
positive regulation of synaptic transmission glutamatergic GO:0051968 13 0.016
Mouse Rat
sexual reproduction GO:0019953 148 0.016
Fly
neuronal stem cell division GO:0036445 1 0.016
single organism reproductive process GO:0044702 297 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
single organism catabolic process GO:0044712 283 0.016
positive regulation of cell motility GO:2000147 97 0.016
phosphatidylinositol dephosphorylation GO:0046856 4 0.016
negative regulation of locomotion GO:0040013 41 0.016
regulation of protein transport GO:0051223 68 0.015
regulation of transmembrane transporter activity GO:0022898 49 0.015
Mouse Rat
maintenance of location GO:0051235 17 0.015
morphogenesis of embryonic epithelium GO:0016331 3 0.015
response to extracellular stimulus GO:0009991 380 0.015
purine containing compound catabolic process GO:0072523 138 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
cell proliferation in external granule layer GO:0021924 1 0.015
regulation of camp metabolic process GO:0030814 43 0.015
somatostatin receptor signaling pathway GO:0038169 4 0.015
response to lipopolysaccharide GO:0032496 191 0.015
membrane depolarization GO:0051899 32 0.015
Mouse Rat
establishment of neuroblast polarity GO:0045200 1 0.015
receptor metabolic process GO:0043112 18 0.015
locomotory exploration behavior GO:0035641 1 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
heart morphogenesis GO:0003007 3 0.014
neuron death GO:0070997 127 0.014
heart contraction GO:0060047 57 0.014
regulation of catalytic activity GO:0050790 304 0.014
regulation of establishment of protein localization GO:0070201 69 0.014
protein homooligomerization GO:0051260 91 0.014
regulation of ion homeostasis GO:2000021 63 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
positive regulation of response to external stimulus GO:0032103 51 0.014
calcium ion transport GO:0006816 131 0.014
choline transport GO:0015871 4 0.014
divalent metal ion transport GO:0070838 132 0.014
regulation of map kinase activity GO:0043405 53 0.014
vasoconstriction GO:0042310 54 0.014
cell cycle GO:0007049 101 0.014
regulation of hydrolase activity GO:0051336 143 0.014
response to light stimulus GO:0009416 52 0.014
Mouse
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.013
triglyceride homeostasis GO:0070328 2 0.013
positive regulation of camp biosynthetic process GO:0030819 28 0.013
presynaptic membrane assembly GO:0097105 3 0.013
positive regulation of blood circulation GO:1903524 65 0.013
dendrite development GO:0016358 72 0.013
Mouse Rat
negative regulation of metabolic process GO:0009892 331 0.013
response to amine GO:0014075 46 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
urinary tract smooth muscle contraction GO:0014848 4 0.013
response to wounding GO:0009611 254 0.013
single organism organelle organization GO:1902589 180 0.013
regulation of axon extension GO:0030516 24 0.013
hair cell differentiation GO:0035315 2 0.013
generation of precursor metabolites and energy GO:0006091 62 0.013
regulation of dendrite development GO:0050773 59 0.013
Mouse Rat
response to monosaccharide GO:0034284 159 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
regulation of calcium ion transport GO:0051924 77 0.013
response to electrical stimulus GO:0051602 56 0.013
endocytosis GO:0006897 84 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
regulation of developmental growth GO:0048638 45 0.013
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.013
programmed cell death GO:0012501 392 0.012
regulation of molecular function GO:0065009 398 0.012
Mouse Rat
receptor internalization GO:0031623 14 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
establishment of vesicle localization GO:0051650 31 0.012
Rat
regulation of cellular response to stress GO:0080135 49 0.012
calcium ion dependent exocytosis GO:0017156 16 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
positive regulation of transferase activity GO:0051347 81 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
synaptic vesicle transport GO:0048489 23 0.012
Rat
positive regulation of neuron differentiation GO:0045666 126 0.012
Rat
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
cellular response to alkaloid GO:0071312 25 0.012
acidic amino acid transport GO:0015800 10 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
organic substance catabolic process GO:1901575 316 0.012

Nlgn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.040
disease of anatomical entity DOID:7 0 0.040
cardiovascular system disease DOID:1287 0 0.040
central nervous system disease DOID:331 0 0.036
brain disease DOID:936 0 0.036
nervous system disease DOID:863 0 0.036
epilepsy syndrome DOID:1826 0 0.028
gastrointestinal system cancer DOID:3119 0 0.020
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.012