Rattus norvegicus

0 known processes

Il12a

interleukin 12A

Il12a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to peptide GO:1901652 292 0.399
response to peptide hormone GO:0043434 278 0.169
cellular amino acid metabolic process GO:0006520 107 0.125
organic acid metabolic process GO:0006082 292 0.108
response to nutrient levels GO:0031667 370 0.105
homeostatic process GO:0042592 331 0.099
cellular component movement GO:0006928 248 0.094
neuropeptide signaling pathway GO:0007218 29 0.093
cellular response to oxygen containing compound GO:1901701 386 0.088
neurological system process GO:0050877 219 0.077
female pregnancy GO:0007565 122 0.072
regulation of phosphorylation GO:0042325 248 0.067
regulation of nervous system development GO:0051960 264 0.067
carboxylic acid metabolic process GO:0019752 289 0.066
cytosolic calcium ion homeostasis GO:0051480 140 0.064
metal ion transport GO:0030001 289 0.064
regulation of cellular amine metabolic process GO:0033238 8 0.064
cellular calcium ion homeostasis GO:0006874 160 0.063
cellular amine metabolic process GO:0044106 38 0.061
hormone secretion GO:0046879 115 0.060
organelle organization GO:0006996 266 0.060
regulation of cellular component movement GO:0051270 150 0.055
regulation of cellular localization GO:0060341 263 0.055
regulation of cell differentiation GO:0045595 320 0.053
amine metabolic process GO:0009308 38 0.053
regulation of peptide transport GO:0090087 87 0.051
immune system process GO:0002376 204 0.051
neuron development GO:0048666 286 0.050
divalent inorganic cation homeostasis GO:0072507 165 0.049
response to oxygen levels GO:0070482 265 0.049
response to other organism GO:0051707 220 0.048
response to lipopolysaccharide GO:0032496 191 0.047
single organism intracellular transport GO:1902582 166 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
cellular ion homeostasis GO:0006873 184 0.046
regulation of cellular protein metabolic process GO:0032268 267 0.045
cell motility GO:0048870 202 0.045
metal ion homeostasis GO:0055065 186 0.043
signal release GO:0023061 145 0.043
regulation of cell proliferation GO:0042127 359 0.042
negative regulation of molecular function GO:0044092 133 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.041
neuron projection development GO:0031175 273 0.039
single organism organelle organization GO:1902589 180 0.039
positive regulation of cell differentiation GO:0045597 217 0.039
calcium ion transport GO:0006816 131 0.039
response to decreased oxygen levels GO:0036293 237 0.039
regulation of cell motility GO:2000145 131 0.039
positive regulation of secretion by cell GO:1903532 128 0.038
aging GO:0007568 241 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.037
regulation of neuron projection development GO:0010975 161 0.037
neuron differentiation GO:0030182 368 0.036
organic substance catabolic process GO:1901575 316 0.036
protein phosphorylation GO:0006468 345 0.036
reactive oxygen species metabolic process GO:0072593 37 0.035
calcium ion homeostasis GO:0055074 162 0.035
cellular ketone metabolic process GO:0042180 51 0.035
cellular divalent inorganic cation homeostasis GO:0072503 162 0.035
cellular homeostasis GO:0019725 252 0.035
intracellular signal transduction GO:0035556 314 0.034
response to extracellular stimulus GO:0009991 380 0.034
cellular metal ion homeostasis GO:0006875 172 0.034
response to inorganic substance GO:0010035 377 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
cellular chemical homeostasis GO:0055082 247 0.033
sodium ion transport GO:0006814 82 0.033
negative regulation of secretion by cell GO:1903531 72 0.032
tissue development GO:0009888 252 0.032
negative regulation of signaling GO:0023057 157 0.032
regulation of programmed cell death GO:0043067 341 0.031
peptidyl amino acid modification GO:0018193 126 0.031
response to external biotic stimulus GO:0043207 221 0.031
response to estrogen GO:0043627 232 0.030
response to radiation GO:0009314 137 0.030
intracellular transport GO:0046907 185 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
regulation of neuron differentiation GO:0045664 208 0.030
regulation of hydrolase activity GO:0051336 143 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
response to carbohydrate GO:0009743 183 0.028
response to acid chemical GO:0001101 222 0.028
cellular cation homeostasis GO:0030003 180 0.028
behavior GO:0007610 205 0.028
regulation of cell migration GO:0030334 128 0.028
peptide hormone secretion GO:0030072 84 0.028
catabolic process GO:0009056 351 0.028
positive regulation of immune system process GO:0002684 90 0.028
salivary gland development GO:0007431 3 0.027
cytoplasmic transport GO:0016482 115 0.027
ion homeostasis GO:0050801 212 0.027
regulation of neurogenesis GO:0050767 247 0.027
divalent inorganic cation transport GO:0072511 134 0.026
regulation of immune system process GO:0002682 123 0.026
regulation of cell development GO:0060284 263 0.026
cellular carbohydrate metabolic process GO:0044262 72 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
positive regulation of peptide secretion GO:0002793 52 0.025
regulation of jak stat cascade GO:0046425 21 0.025
regulation of secretion by cell GO:1903530 208 0.025
negative regulation of metabolic process GO:0009892 331 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
regulation of locomotion GO:0040012 148 0.025
establishment of protein localization GO:0045184 141 0.025
negative regulation of cell death GO:0060548 229 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
response to hypoxia GO:0001666 231 0.024
phenol containing compound metabolic process GO:0018958 30 0.024
action potential GO:0001508 54 0.024
defense response GO:0006952 194 0.024
sequestering of metal ion GO:0051238 9 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
brain development GO:0007420 247 0.023
jak stat cascade GO:0007259 26 0.023
positive regulation of peptide hormone secretion GO:0090277 50 0.023
regulation of cellular component organization GO:0051128 368 0.023
immune response GO:0006955 104 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
negative regulation of transport GO:0051051 136 0.023
regulation of protein metabolic process GO:0051246 289 0.023
regulation of apoptotic process GO:0042981 335 0.023
programmed cell death GO:0012501 392 0.022
apoptotic process GO:0006915 381 0.022
regulation of behavior GO:0050795 61 0.022
response to nicotine GO:0035094 51 0.022
sequestering of calcium ion GO:0051208 8 0.022
hormone transport GO:0009914 121 0.022
regulation of anatomical structure size GO:0090066 135 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
negative regulation of catalytic activity GO:0043086 103 0.021
regulation of peptide hormone secretion GO:0090276 80 0.021
positive regulation of hormone secretion GO:0046887 65 0.021
response to reactive oxygen species GO:0000302 120 0.021
protein transport GO:0015031 132 0.021
single organism behavior GO:0044708 130 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
regulation of reactive oxygen species metabolic process GO:2000377 26 0.020
peptide transport GO:0015833 97 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
motor neuron axon guidance GO:0008045 1 0.020
central nervous system development GO:0007417 311 0.020
blood circulation GO:0008015 183 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
inflammatory response GO:0006954 150 0.020
multi multicellular organism process GO:0044706 138 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
secretion GO:0046903 307 0.020
response to metal ion GO:0010038 253 0.020
regulation of membrane potential GO:0042391 110 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
regulation of peptide secretion GO:0002791 82 0.019
response to oxidative stress GO:0006979 186 0.019
regulation of cell projection organization GO:0031344 175 0.019
regeneration GO:0031099 163 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
adult locomotory behavior GO:0008344 4 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
phasic smooth muscle contraction GO:0014821 3 0.019
positive regulation of jak stat cascade GO:0046427 19 0.019
developmental growth GO:0048589 100 0.019
digestion GO:0007586 26 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
cell cell signaling GO:0007267 335 0.018
peptide secretion GO:0002790 86 0.018
response to mineralocorticoid GO:0051385 49 0.018
positive regulation of cell development GO:0010720 176 0.018
calcium ion transport into cytosol GO:0060402 38 0.018
multi organism reproductive process GO:0044703 262 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
cellular response to lipid GO:0071396 201 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
protein complex biogenesis GO:0070271 263 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.018
cation homeostasis GO:0055080 195 0.018
regulation of axonogenesis GO:0050770 37 0.018
positive regulation of hydrolase activity GO:0051345 86 0.017
regulation of catalytic activity GO:0050790 304 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
cation transport GO:0006812 382 0.017
cellular response to stress GO:0033554 269 0.017
renal system development GO:0072001 67 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
axon development GO:0061564 96 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
positive regulation of leukocyte activation GO:0002696 30 0.016
positive regulation of cell communication GO:0010647 271 0.016
transmission of nerve impulse GO:0019226 42 0.016
cellular response to tumor necrosis factor GO:0071356 46 0.016
response to biotic stimulus GO:0009607 226 0.016
regulation of leukocyte activation GO:0002694 45 0.016
calcium ion import GO:0070509 22 0.016
response to glucose GO:0009749 136 0.016
positive regulation of signaling GO:0023056 270 0.016
learning GO:0007612 33 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
regulation of hormone secretion GO:0046883 106 0.015
response to corticosteroid GO:0031960 235 0.015
positive regulation of locomotion GO:0040017 102 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
cellular component assembly GO:0022607 360 0.015
amide transport GO:0042886 105 0.015
response to bacterium GO:0009617 200 0.015
sensory organ development GO:0007423 74 0.015
regulation of axon extension GO:0030516 24 0.015
regulation of neuron death GO:1901214 115 0.015
cytoskeleton organization GO:0007010 111 0.015
cellular response to peptide GO:1901653 133 0.015
regulation of system process GO:0044057 208 0.014
regulation of protein modification process GO:0031399 194 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
response to cytokine GO:0034097 215 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
regulation of metal ion transport GO:0010959 118 0.014
positive regulation of developmental process GO:0051094 283 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
chemical homeostasis GO:0048878 292 0.014
response to hexose GO:0009746 144 0.014
negative regulation of cell communication GO:0010648 158 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
macromolecular complex subunit organization GO:0043933 339 0.013
regulation of extent of cell growth GO:0061387 25 0.013
response to estradiol GO:0032355 164 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
protein complex subunit organization GO:0071822 302 0.013
response to light stimulus GO:0009416 52 0.013
proteolysis GO:0006508 175 0.013
axonogenesis GO:0007409 71 0.013
gland development GO:0048732 155 0.013
regulation of insulin secretion GO:0050796 65 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
organelle localization GO:0051640 55 0.013
regulation of response to external stimulus GO:0032101 106 0.013
regulation of molecular function GO:0065009 398 0.013
ras protein signal transduction GO:0007265 29 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
heterocycle catabolic process GO:0046700 167 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of hormone secretion GO:0046888 46 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
locomotion GO:0040011 237 0.013
response to food GO:0032094 27 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
regulation of protein transport GO:0051223 68 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
positive regulation of cell activation GO:0050867 34 0.013
response to electrical stimulus GO:0051602 56 0.013
chemotaxis GO:0006935 66 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of ion transport GO:0043269 245 0.013
cell projection organization GO:0030030 302 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
positive regulation of gene expression GO:0010628 244 0.012
circulatory system process GO:0003013 183 0.012
leukocyte activation GO:0045321 76 0.012
response to corticosterone GO:0051412 40 0.012
response to axon injury GO:0048678 59 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
insulin secretion GO:0030073 69 0.012
gliogenesis GO:0042063 93 0.012
regulation of secretion GO:0051046 224 0.012
negative regulation of cell development GO:0010721 82 0.012
positive regulation of long term synaptic potentiation GO:1900273 4 0.012
response to alkaloid GO:0043279 132 0.012
sensory perception GO:0007600 101 0.012
negative regulation of nervous system development GO:0051961 79 0.012
sensory perception of pain GO:0019233 73 0.012
regulation of intracellular transport GO:0032386 65 0.012
intracellular protein transport GO:0006886 79 0.012
response to hydrogen peroxide GO:0042542 89 0.012
nitrogen compound transport GO:0071705 229 0.012
response to toxic substance GO:0009636 133 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
cation transmembrane transport GO:0098655 263 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
localization of cell GO:0051674 202 0.012
head development GO:0060322 247 0.012
growth GO:0040007 165 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.011
response to ethanol GO:0045471 162 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
amino acid transport GO:0006865 70 0.011
secretion by cell GO:0032940 248 0.011
cell type specific apoptotic process GO:0097285 134 0.011
cell migration GO:0016477 197 0.011
response to tumor necrosis factor GO:0034612 56 0.011
actin filament based process GO:0030029 86 0.011
dna metabolic process GO:0006259 96 0.011
epithelium development GO:0060429 96 0.011
oxoacid metabolic process GO:0043436 290 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
negative regulation of neuron death GO:1901215 69 0.011
positive regulation of response to external stimulus GO:0032103 51 0.011
negative regulation of response to external stimulus GO:0032102 37 0.011
muscle cell proliferation GO:0033002 84 0.011
developmental growth involved in morphogenesis GO:0060560 33 0.011
regulation of saliva secretion GO:0046877 3 0.011
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.011
regulation of cell cycle GO:0051726 73 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
associative learning GO:0008306 19 0.011
response to monosaccharide GO:0034284 159 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
negative regulation of secretion GO:0051048 82 0.011
response to growth factor GO:0070848 189 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
neuron death GO:0070997 127 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
rhythmic behavior GO:0007622 24 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
carbohydrate metabolic process GO:0005975 130 0.010
nucleocytoplasmic transport GO:0006913 48 0.010
regulation of nucleic acid templated transcription GO:1903506 380 0.010

Il12a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
nervous system disease DOID:863 0 0.063
central nervous system disease DOID:331 0 0.025