Rattus norvegicus

0 known processes

Tiam1

T-cell lymphoma invasion and metastasis 1

Tiam1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.124
oxoacid metabolic process GO:0043436 290 0.103
neuron development GO:0048666 286 0.085
regulation of cellular component organization GO:0051128 368 0.078
regulation of multicellular organismal development GO:2000026 376 0.076
neuron projection development GO:0031175 273 0.071
carboxylic acid metabolic process GO:0019752 289 0.069
regulation of cell projection organization GO:0031344 175 0.066
ion transmembrane transport GO:0034220 365 0.060
transmembrane transport GO:0055085 412 0.059
cell projection organization GO:0030030 302 0.057
regulation of nervous system development GO:0051960 264 0.055
response to peptide hormone GO:0043434 278 0.054
neuron differentiation GO:0030182 368 0.048
response to nutrient GO:0007584 248 0.048
cellular component assembly GO:0022607 360 0.048
regulation of neuron projection development GO:0010975 161 0.047
regulation of cell differentiation GO:0045595 320 0.046
regulation of neurogenesis GO:0050767 247 0.046
macromolecular complex subunit organization GO:0043933 339 0.045
protein complex subunit organization GO:0071822 302 0.045
cellular amine metabolic process GO:0044106 38 0.043
cellular ketone metabolic process GO:0042180 51 0.042
inorganic cation transmembrane transport GO:0098662 202 0.041
cell motility GO:0048870 202 0.041
regulation of neuron differentiation GO:0045664 208 0.040
transcription dna templated GO:0006351 377 0.039
regulation of phosphorus metabolic process GO:0051174 349 0.039
cation transmembrane transport GO:0098655 263 0.038
response to extracellular stimulus GO:0009991 380 0.038
response to nutrient levels GO:0031667 370 0.038
positive regulation of developmental process GO:0051094 283 0.038
cellular component biogenesis GO:0044085 368 0.037
protein complex assembly GO:0006461 263 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.036
cellular response to peptide hormone stimulus GO:0071375 120 0.036
central nervous system development GO:0007417 311 0.036
inorganic ion transmembrane transport GO:0098660 229 0.036
anterior posterior pattern specification GO:0009952 1 0.035
regulation of cell development GO:0060284 263 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
metal ion transport GO:0030001 289 0.035
response to oxygen levels GO:0070482 265 0.034
protein complex biogenesis GO:0070271 263 0.034
cellular response to stress GO:0033554 269 0.034
cell projection morphogenesis GO:0048858 123 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
negative regulation of metabolic process GO:0009892 331 0.034
response to inorganic substance GO:0010035 377 0.033
regulation of anatomical structure morphogenesis GO:0022603 141 0.033
macromolecular complex assembly GO:0065003 273 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
response to glucocorticoid GO:0051384 223 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.030
positive regulation of cell communication GO:0010647 271 0.030
negative regulation of cell development GO:0010721 82 0.030
catabolic process GO:0009056 351 0.030
regulation of phosphate metabolic process GO:0019220 349 0.029
cellular homeostasis GO:0019725 252 0.029
ion homeostasis GO:0050801 212 0.029
brain development GO:0007420 247 0.028
cellular component morphogenesis GO:0032989 155 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.028
response to wounding GO:0009611 254 0.028
nucleic acid templated transcription GO:0097659 379 0.028
cellular chemical homeostasis GO:0055082 247 0.028
metal ion homeostasis GO:0055065 186 0.028
response to decreased oxygen levels GO:0036293 237 0.028
regeneration GO:0031099 163 0.028
rna biosynthetic process GO:0032774 380 0.028
nucleotide metabolic process GO:0009117 279 0.028
regulation of signal transduction GO:0009966 318 0.028
cellular response to oxygen containing compound GO:1901701 386 0.027
positive regulation of neuron projection development GO:0010976 99 0.027
regulation of protein metabolic process GO:0051246 289 0.027
cellular cation homeostasis GO:0030003 180 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
organic substance catabolic process GO:1901575 316 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
cell morphogenesis GO:0000902 142 0.026
carboxylic acid transport GO:0046942 115 0.026
single organism organelle organization GO:1902589 180 0.026
response to growth factor GO:0070848 189 0.026
response to peptide GO:1901652 292 0.026
rna metabolic process GO:0016070 406 0.026
head development GO:0060322 247 0.026
regulation of transcription dna templated GO:0006355 374 0.026
organophosphate metabolic process GO:0019637 370 0.026
proteolysis GO:0006508 175 0.026
regulation of molecular function GO:0065009 398 0.026
anion transport GO:0006820 178 0.026
cation transport GO:0006812 382 0.026
cellular component movement GO:0006928 248 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
negative regulation of protein metabolic process GO:0051248 114 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
neuron projection morphogenesis GO:0048812 122 0.025
reproduction GO:0000003 245 0.025
regulation of dendrite development GO:0050773 59 0.025
amine metabolic process GO:0009308 38 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
negative regulation of gene expression GO:0010629 199 0.025
cellular catabolic process GO:0044248 295 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
regulation of cellular component movement GO:0051270 150 0.024
positive regulation of nervous system development GO:0051962 178 0.024
response to purine containing compound GO:0014074 126 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
tissue development GO:0009888 252 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
chemical homeostasis GO:0048878 292 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
synaptic transmission GO:0007268 235 0.023
regulation of phosphorylation GO:0042325 248 0.023
embryonic skeletal system development GO:0048706 3 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
response to cytokine GO:0034097 215 0.023
single organism reproductive process GO:0044702 297 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
organic anion transport GO:0015711 132 0.023
cellular lipid metabolic process GO:0044255 208 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
response to carbohydrate GO:0009743 183 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
homeostatic process GO:0042592 331 0.022
positive regulation of cell development GO:0010720 176 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
lipid metabolic process GO:0006629 283 0.022
multi organism reproductive process GO:0044703 262 0.021
response to corticosteroid GO:0031960 235 0.021
positive regulation of cell projection organization GO:0031346 111 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
cation homeostasis GO:0055080 195 0.021
locomotion GO:0040011 237 0.021
bmp signaling pathway GO:0030509 4 0.021
response to metal ion GO:0010038 253 0.021
secretion GO:0046903 307 0.021
regulation of hormone levels GO:0010817 187 0.021
intracellular signal transduction GO:0035556 314 0.021
gastrulation GO:0007369 2 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
regulation of rna metabolic process GO:0051252 391 0.021
regulation of cell proliferation GO:0042127 359 0.021
calcium ion homeostasis GO:0055074 162 0.021
organelle organization GO:0006996 266 0.021
response to axon injury GO:0048678 59 0.021
protein oligomerization GO:0051259 191 0.021
cytoskeleton organization GO:0007010 111 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
protein phosphorylation GO:0006468 345 0.020
single organism intracellular transport GO:1902582 166 0.020
regulation of cell morphogenesis GO:0022604 77 0.020
negative regulation of neurogenesis GO:0050768 78 0.020
response to hexose GO:0009746 144 0.020
single organism biosynthetic process GO:0044711 342 0.020
response to hypoxia GO:0001666 231 0.020
single organism catabolic process GO:0044712 283 0.020
dendrite development GO:0016358 72 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
regulation of protein modification process GO:0031399 194 0.020
cellular ion homeostasis GO:0006873 184 0.020
divalent inorganic cation transport GO:0072511 134 0.019
aging GO:0007568 241 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
cell adhesion GO:0007155 110 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
cell part morphogenesis GO:0032990 123 0.019
multicellular organism reproduction GO:0032504 233 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
organic acid transport GO:0015849 116 0.019
regulation of programmed cell death GO:0043067 341 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
sensory organ development GO:0007423 74 0.019
oxidation reduction process GO:0055114 304 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.018
response to oxidative stress GO:0006979 186 0.018
growth GO:0040007 165 0.018
regulation of catalytic activity GO:0050790 304 0.018
reproductive process GO:0022414 372 0.018
feeding behavior GO:0007631 53 0.018
axon development GO:0061564 96 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.018
programmed cell death GO:0012501 392 0.018
negative regulation of nervous system development GO:0051961 79 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
response to acid chemical GO:0001101 222 0.017
cell growth GO:0016049 104 0.017
neuron death GO:0070997 127 0.017
gliogenesis GO:0042063 93 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.016
calcium ion transport GO:0006816 131 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
regulation of anatomical structure size GO:0090066 135 0.016
positive regulation of molecular function GO:0044093 230 0.016
cell cell signaling GO:0007267 335 0.016
developmental process involved in reproduction GO:0003006 159 0.016
embryonic skeletal system morphogenesis GO:0048704 3 0.016
regulation of locomotion GO:0040012 148 0.016
intracellular transport GO:0046907 185 0.016
regulation of axonogenesis GO:0050770 37 0.016
apoptotic process GO:0006915 381 0.016
purine containing compound metabolic process GO:0072521 253 0.016
localization of cell GO:0051674 202 0.016
sexual reproduction GO:0019953 148 0.016
vesicle mediated transport GO:0016192 181 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
multi multicellular organism process GO:0044706 138 0.016
negative regulation of molecular function GO:0044092 133 0.016
nitrogen compound transport GO:0071705 229 0.016
positive regulation of biosynthetic process GO:0009891 319 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
biological adhesion GO:0022610 110 0.015
actin filament based process GO:0030029 86 0.015
gland development GO:0048732 155 0.015
cellular response to peptide GO:1901653 133 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
neurological system process GO:0050877 219 0.015
response to amino acid GO:0043200 75 0.015
regulation of ion transport GO:0043269 245 0.015
calcium ion transmembrane transport GO:0070588 70 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
ras protein signal transduction GO:0007265 29 0.014
positive regulation of signaling GO:0023056 270 0.014
macromolecule localization GO:0033036 252 0.014
heart morphogenesis GO:0003007 3 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
small molecule catabolic process GO:0044282 59 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
cellular response to external stimulus GO:0071496 118 0.014
cell migration GO:0016477 197 0.014
cellular amino acid catabolic process GO:0009063 21 0.014
positive regulation of gene expression GO:0010628 244 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
regulation of cell migration GO:0030334 128 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
cardiovascular system development GO:0072358 134 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
divalent metal ion transport GO:0070838 132 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
positive regulation of protein modification process GO:0031401 142 0.013
salivary gland development GO:0007431 3 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
sequestering of calcium ion GO:0051208 8 0.013
urogenital system development GO:0001655 78 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
embryonic pattern specification GO:0009880 1 0.013
regulation of cell growth GO:0001558 85 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
response to ketone GO:1901654 182 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
response to vitamin GO:0033273 131 0.012
peptidyl amino acid modification GO:0018193 126 0.012
multicellular organism growth GO:0035264 1 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
motor neuron axon guidance GO:0008045 1 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
response to alkaloid GO:0043279 132 0.012
central nervous system neuron axonogenesis GO:0021955 1 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
regulation of system process GO:0044057 208 0.012
anion transmembrane transport GO:0098656 77 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
organic acid catabolic process GO:0016054 49 0.012
female pregnancy GO:0007565 122 0.012
regulation of homeostatic process GO:0032844 101 0.012
negative regulation of developmental process GO:0051093 125 0.012
developmental growth GO:0048589 100 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
response to estrogen GO:0043627 232 0.011
eye morphogenesis GO:0048592 4 0.011
positive regulation of cell death GO:0010942 184 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
axis specification GO:0009798 4 0.011
regulation of catabolic process GO:0009894 113 0.011
heterocycle catabolic process GO:0046700 167 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
establishment of tissue polarity GO:0007164 2 0.011
alpha amino acid metabolic process GO:1901605 71 0.011
potassium ion transport GO:0006813 97 0.011
negative regulation of signaling GO:0023057 157 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
chemosensory behavior GO:0007635 2 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
salivary gland morphogenesis GO:0007435 1 0.011
maintenance of location GO:0051235 17 0.011
rhythmic process GO:0048511 156 0.011
learning or memory GO:0007611 90 0.011
renal system development GO:0072001 67 0.011
nucleoside metabolic process GO:0009116 179 0.011
adult locomotory behavior GO:0008344 4 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
regulation of cell adhesion GO:0030155 52 0.011
behavior GO:0007610 205 0.011
cellular protein localization GO:0034613 122 0.011
reproductive structure development GO:0048608 128 0.010
protein maturation GO:0051604 68 0.010
lipid storage GO:0019915 1 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
fatty acid metabolic process GO:0006631 99 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
mapk cascade GO:0000165 140 0.010
negative regulation of secretion GO:0051048 82 0.010
hormone metabolic process GO:0042445 69 0.010
regulation of membrane potential GO:0042391 110 0.010
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
epithelium development GO:0060429 96 0.010
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
aromatic compound catabolic process GO:0019439 168 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
negative regulation of cell communication GO:0010648 158 0.010
neural crest cell differentiation GO:0014033 2 0.010
response to monosaccharide GO:0034284 159 0.010
gamete generation GO:0007276 124 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
male mating behavior GO:0060179 3 0.010

Tiam1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
central nervous system disease DOID:331 0 0.014
musculoskeletal system disease DOID:17 0 0.011