Rattus norvegicus

0 known processes

Klk8

kallikrein related-peptidase 8

(Aliases: bsp1)

Klk8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.408
Rat
response to biotic stimulus GO:0009607 226 0.331
response to molecule of bacterial origin GO:0002237 194 0.327
response to nutrient GO:0007584 248 0.314
Rat
response to oxidative stress GO:0006979 186 0.232
single organism biosynthetic process GO:0044711 342 0.226
cellular lipid metabolic process GO:0044255 208 0.213
response to acid chemical GO:0001101 222 0.199
response to other organism GO:0051707 220 0.196
response to external biotic stimulus GO:0043207 221 0.189
lipid metabolic process GO:0006629 283 0.179
organophosphate biosynthetic process GO:0090407 143 0.178
single organism catabolic process GO:0044712 283 0.164
response to inorganic substance GO:0010035 377 0.161
positive regulation of cell development GO:0010720 176 0.139
response to peptide hormone GO:0043434 278 0.135
response to glucocorticoid GO:0051384 223 0.130
regulation of cell proliferation GO:0042127 359 0.126
response to lipopolysaccharide GO:0032496 191 0.124
response to corticosteroid GO:0031960 235 0.121
response to reactive oxygen species GO:0000302 120 0.119
organic hydroxy compound metabolic process GO:1901615 115 0.113
organophosphate metabolic process GO:0019637 370 0.113
multi organism reproductive process GO:0044703 262 0.113
reproductive process GO:0022414 372 0.109
response to peptide GO:1901652 292 0.107
regulation of metal ion transport GO:0010959 118 0.105
lipid biosynthetic process GO:0008610 128 0.102
response to purine containing compound GO:0014074 126 0.100
Rat
oxoacid metabolic process GO:0043436 290 0.099
positive regulation of kinase activity GO:0033674 77 0.098
glycosyl compound metabolic process GO:1901657 182 0.095
response to amino acid GO:0043200 75 0.093
regulation of molecular function GO:0065009 398 0.093
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.090
alcohol metabolic process GO:0006066 77 0.090
organonitrogen compound biosynthetic process GO:1901566 167 0.085
multicellular organism reproduction GO:0032504 233 0.084
carboxylic acid metabolic process GO:0019752 289 0.083
cellular response to acid chemical GO:0071229 75 0.082
nucleotide metabolic process GO:0009117 279 0.080
response to nutrient levels GO:0031667 370 0.080
Rat
single organism reproductive process GO:0044702 297 0.079
cellular response to oxygen containing compound GO:1901701 386 0.078
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.077
cellular response to endogenous stimulus GO:0071495 377 0.076
regulation of cellular localization GO:0060341 263 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.076
cellular amine metabolic process GO:0044106 38 0.076
ribonucleotide biosynthetic process GO:0009260 85 0.074
organic acid metabolic process GO:0006082 292 0.073
carboxylic acid transport GO:0046942 115 0.073
heart morphogenesis GO:0003007 3 0.072
positive regulation of lipid kinase activity GO:0090218 2 0.071
nucleoside metabolic process GO:0009116 179 0.068
aging GO:0007568 241 0.065
regulation of nervous system development GO:0051960 264 0.065
Mouse Rat
response to bacterium GO:0009617 200 0.064
purine nucleoside metabolic process GO:0042278 169 0.063
cellular response to organonitrogen compound GO:0071417 197 0.063
regulation of cell development GO:0060284 263 0.061
Mouse Rat
phospholipid metabolic process GO:0006644 61 0.061
acrosome assembly GO:0001675 3 0.060
multicellular organismal reproductive process GO:0048609 233 0.060
peptidyl amino acid modification GO:0018193 126 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.059
response to hypoxia GO:0001666 231 0.057
organelle organization GO:0006996 266 0.055
ribonucleoside metabolic process GO:0009119 174 0.055
positive regulation of blood circulation GO:1903524 65 0.054
Rat
response to ethanol GO:0045471 162 0.054
cellular response to lipid GO:0071396 201 0.054
secretion GO:0046903 307 0.054
response to temperature stimulus GO:0009266 94 0.054
steroid metabolic process GO:0008202 73 0.053
amine metabolic process GO:0009308 38 0.052
cell cell signaling GO:0007267 335 0.051
Mouse
regulation of neuron differentiation GO:0045664 208 0.051
Mouse Rat
neurological system process GO:0050877 219 0.050
Mouse
response to cytokine GO:0034097 215 0.050
positive regulation of intracellular signal transduction GO:1902533 138 0.049
nucleoside phosphate metabolic process GO:0006753 283 0.049
response to metal ion GO:0010038 253 0.049
positive regulation of catalytic activity GO:0043085 184 0.049
response to estradiol GO:0032355 164 0.049
ribose phosphate metabolic process GO:0019693 235 0.049
gliogenesis GO:0042063 93 0.049
positive regulation of molecular function GO:0044093 230 0.048
regulation of lipid metabolic process GO:0019216 68 0.048
organic anion transport GO:0015711 132 0.048
positive regulation of cell death GO:0010942 184 0.047
cellular component biogenesis GO:0044085 368 0.046
response to oxygen levels GO:0070482 265 0.045
peptidyl tyrosine modification GO:0018212 72 0.045
reproduction GO:0000003 245 0.044
cellular response to external stimulus GO:0071496 118 0.044
cyclic purine nucleotide metabolic process GO:0052652 62 0.044
negative regulation of transport GO:0051051 136 0.044
developmental process involved in reproduction GO:0003006 159 0.043
response to decreased oxygen levels GO:0036293 237 0.043
negative regulation of gene expression GO:0010629 199 0.043
nucleoside triphosphate metabolic process GO:0009141 144 0.043
regulation of catalytic activity GO:0050790 304 0.043
positive regulation of cell proliferation GO:0008284 249 0.042
protein phosphorylation GO:0006468 345 0.042
cellular response to nitrogen compound GO:1901699 210 0.041
carbohydrate derivative catabolic process GO:1901136 147 0.041
cellular ketone metabolic process GO:0042180 51 0.041
response to toxic substance GO:0009636 133 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
cgmp biosynthetic process GO:0006182 15 0.040
organophosphate catabolic process GO:0046434 148 0.039
cellular response to stress GO:0033554 269 0.039
Mouse
protein complex assembly GO:0006461 263 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
response to antibiotic GO:0046677 39 0.038
regulation of cell differentiation GO:0045595 320 0.038
Mouse Rat
response to alkaloid GO:0043279 132 0.038
Rat
cellular amino acid metabolic process GO:0006520 107 0.037
regulation of neurogenesis GO:0050767 247 0.037
Mouse Rat
positive regulation of apoptotic process GO:0043065 154 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.037
Rat
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.037
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.036
purine ribonucleotide catabolic process GO:0009154 136 0.035
single organism organelle organization GO:1902589 180 0.035
regulation of tube size GO:0035150 89 0.035
Rat
central nervous system development GO:0007417 311 0.035
aromatic compound catabolic process GO:0019439 168 0.035
homeostatic process GO:0042592 331 0.035
transmembrane transport GO:0055085 412 0.035
multi multicellular organism process GO:0044706 138 0.034
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.034
cellular response to extracellular stimulus GO:0031668 73 0.034
cellular response to metal ion GO:0071248 55 0.034
regulation of cellular component organization GO:0051128 368 0.033
Mouse Rat
cell morphogenesis GO:0000902 142 0.033
Mouse
muscle system process GO:0003012 115 0.033
positive regulation of programmed cell death GO:0043068 157 0.033
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.033
glycerolipid metabolic process GO:0046486 67 0.033
phospholipid biosynthetic process GO:0008654 29 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
digestion GO:0007586 26 0.033
response to carbohydrate GO:0009743 183 0.032
purine containing compound metabolic process GO:0072521 253 0.032
macromolecular complex assembly GO:0065003 273 0.032
divalent inorganic cation transport GO:0072511 134 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
regulation of secretion GO:0051046 224 0.031
cellular component assembly GO:0022607 360 0.031
vasoconstriction GO:0042310 54 0.031
Rat
glial cell differentiation GO:0010001 65 0.030
anion transport GO:0006820 178 0.030
striated muscle contraction GO:0006941 44 0.030
organic acid transport GO:0015849 116 0.030
nucleoside phosphate biosynthetic process GO:1901293 102 0.030
oxidation reduction process GO:0055114 304 0.030
apoptotic process GO:0006915 381 0.029
ovulation cycle GO:0042698 67 0.029
purine ribonucleotide metabolic process GO:0009150 227 0.029
ribonucleotide metabolic process GO:0009259 231 0.029
cellular response to peptide GO:1901653 133 0.029
regulation of multicellular organismal development GO:2000026 376 0.028
Mouse Rat
response to transition metal nanoparticle GO:1990267 122 0.028
response to vitamin GO:0033273 131 0.028
cellular biogenic amine metabolic process GO:0006576 30 0.028
response to estrogen GO:0043627 232 0.028
ion transmembrane transport GO:0034220 365 0.028
actin cytoskeleton organization GO:0030036 73 0.028
purine nucleotide catabolic process GO:0006195 136 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.028
response to radiation GO:0009314 137 0.028
striated muscle cell development GO:0055002 26 0.028
rna biosynthetic process GO:0032774 380 0.027
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.027
innate immune response GO:0045087 35 0.027
mesoderm development GO:0007498 2 0.027
purine ribonucleotide biosynthetic process GO:0009152 81 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
regulation of secretion by cell GO:1903530 208 0.027
regulation of hormone levels GO:0010817 187 0.027
ribonucleoside triphosphate metabolic process GO:0009199 141 0.027
cellular response to peptide hormone stimulus GO:0071375 120 0.027
regulation of rna metabolic process GO:0051252 391 0.027
growth GO:0040007 165 0.026
ribose phosphate biosynthetic process GO:0046390 87 0.026
cytoskeleton organization GO:0007010 111 0.026
acid secretion GO:0046717 48 0.026
negative regulation of cell death GO:0060548 229 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
regulation of purine nucleotide catabolic process GO:0033121 65 0.025
regulation of protein metabolic process GO:0051246 289 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
catabolic process GO:0009056 351 0.024
response to mineralocorticoid GO:0051385 49 0.024
response to heat GO:0009408 60 0.024
cellular catabolic process GO:0044248 295 0.024
defense response GO:0006952 194 0.024
nucleoside phosphate catabolic process GO:1901292 140 0.024
purine containing compound catabolic process GO:0072523 138 0.024
organic substance catabolic process GO:1901575 316 0.024
positive regulation of cell communication GO:0010647 271 0.024
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.024
tissue development GO:0009888 252 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
epithelial cell differentiation GO:0030855 71 0.024
regulation of saliva secretion GO:0046877 3 0.024
cellular hormone metabolic process GO:0034754 49 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
Mouse
cellular ion homeostasis GO:0006873 184 0.023
protein localization GO:0008104 191 0.023
programmed cell death GO:0012501 392 0.023
carbohydrate metabolic process GO:0005975 130 0.023
single organism carbohydrate metabolic process GO:0044723 118 0.023
regulation of cell growth GO:0001558 85 0.023
regulation of nucleotide metabolic process GO:0006140 117 0.022
small molecule biosynthetic process GO:0044283 124 0.022
protein complex subunit organization GO:0071822 302 0.022
divalent metal ion transport GO:0070838 132 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
cation transmembrane transport GO:0098655 263 0.022
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.022
cellular carbohydrate metabolic process GO:0044262 72 0.022
response to ketone GO:1901654 182 0.022
ribonucleotide catabolic process GO:0009261 136 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
response to hexose GO:0009746 144 0.021
response to retinoic acid GO:0032526 63 0.021
n methyl d aspartate receptor clustering GO:0097114 2 0.021
neurotransmitter gated ion channel clustering GO:0072578 3 0.021
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.021
ribonucleoside monophosphate metabolic process GO:0009161 88 0.021
hippocampus development GO:0021766 30 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
purine nucleoside monophosphate metabolic process GO:0009126 84 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
muscle tissue development GO:0060537 58 0.021
behavior GO:0007610 205 0.021
Mouse
transcription dna templated GO:0006351 377 0.021
sensory perception GO:0007600 101 0.021
regulation of cell projection organization GO:0031344 175 0.021
Mouse Rat
nucleoside catabolic process GO:0009164 126 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
brain development GO:0007420 247 0.021
multicellular organismal homeostasis GO:0048871 49 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
cellular response to inorganic substance GO:0071241 65 0.020
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.020
circulatory system development GO:0072359 134 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.020
protein complex biogenesis GO:0070271 263 0.020
response to growth factor GO:0070848 189 0.020
acute inflammatory response GO:0002526 58 0.020
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.020
positive regulation of long term synaptic potentiation GO:1900273 4 0.020
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.020
gamete generation GO:0007276 124 0.020
intracellular transport GO:0046907 185 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
response to calcium ion GO:0051592 59 0.020
proteolysis GO:0006508 175 0.020
Human Mouse Rat
cellular response to retinoic acid GO:0071300 27 0.020
regulation of lipid kinase activity GO:0043550 7 0.020
cellular homeostasis GO:0019725 252 0.020
regulation of muscle tissue development GO:1901861 25 0.020
muscle structure development GO:0061061 87 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
secondary metabolic process GO:0019748 15 0.019
regulation of phosphorylation GO:0042325 248 0.019
positive regulation of nucleotide metabolic process GO:0045981 91 0.019
male gonad development GO:0008584 59 0.019
response to mechanical stimulus GO:0009612 134 0.019
rna metabolic process GO:0016070 406 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
positive regulation of signal transduction GO:0009967 175 0.019
response to insulin GO:0032868 133 0.019
regulation of apoptotic process GO:0042981 335 0.019
amino acid transport GO:0006865 70 0.019
regulation of smooth muscle cell proliferation GO:0048660 75 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
lymphoid progenitor cell differentiation GO:0002320 2 0.019
peptidyl tyrosine phosphorylation GO:0018108 72 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
regulation of nucleotide biosynthetic process GO:0030808 47 0.019
nucleotide catabolic process GO:0009166 139 0.018
positive regulation of nucleoside metabolic process GO:0045979 55 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
generation of precursor metabolites and energy GO:0006091 62 0.018
c21 steroid hormone biosynthetic process GO:0006700 10 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
learning or memory GO:0007611 90 0.018
Mouse
glycosyl compound catabolic process GO:1901658 126 0.018
anterior posterior pattern specification GO:0009952 1 0.018
nucleoside triphosphate catabolic process GO:0009143 123 0.018
positive regulation of saliva secretion GO:0046878 3 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
b cell differentiation GO:0030183 2 0.018
single organism carbohydrate catabolic process GO:0044724 40 0.018
cell projection morphogenesis GO:0048858 123 0.018
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.018
cyclic nucleotide metabolic process GO:0009187 80 0.018
insecticide metabolic process GO:0017143 4 0.017
positive regulation of signaling GO:0023056 270 0.017
response to wounding GO:0009611 254 0.017
Mouse
leydig cell differentiation GO:0033327 8 0.017
response to activity GO:0014823 73 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
axis specification GO:0009798 4 0.017
regulation of kinase activity GO:0043549 117 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
regulation of neurotransmitter levels GO:0001505 42 0.017
hematopoietic progenitor cell differentiation GO:0002244 2 0.016
protein homooligomerization GO:0051260 91 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
carboxylic acid biosynthetic process GO:0046394 83 0.016
intracellular signal transduction GO:0035556 314 0.016
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.016
positive regulation of lipid metabolic process GO:0045834 33 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
male sex differentiation GO:0046661 64 0.016
organ regeneration GO:0031100 101 0.016
nucleic acid templated transcription GO:0097659 379 0.016
circulatory system process GO:0003013 183 0.016
Rat
response to xenobiotic stimulus GO:0009410 23 0.016
cellular response to nutrient levels GO:0031669 60 0.016
organic hydroxy compound biosynthetic process GO:1901617 51 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
peptide biosynthetic process GO:0043043 3 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
nucleoside monophosphate metabolic process GO:0009123 93 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
regulation of programmed cell death GO:0043067 341 0.015
macromolecule localization GO:0033036 252 0.015
cardiovascular system development GO:0072358 134 0.015
head development GO:0060322 247 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
synaptic transmission glutamatergic GO:0035249 33 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
cellular chemical homeostasis GO:0055082 247 0.015
embryonic cranial skeleton morphogenesis GO:0048701 2 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
alcohol biosynthetic process GO:0046165 38 0.015
regulation of renin secretion into blood stream GO:1900133 1 0.015
cellular component morphogenesis GO:0032989 155 0.015
Mouse
signal release GO:0023061 145 0.015
urinary tract smooth muscle contraction GO:0014848 4 0.015
regulation of homotypic cell cell adhesion GO:0034110 4 0.015
positive regulation of transmembrane transport GO:0034764 25 0.015
single organism cellular localization GO:1902580 102 0.015
reproductive system development GO:0061458 128 0.015
response to caffeine GO:0031000 18 0.015
Rat
neuromuscular process GO:0050905 2 0.015
pallium development GO:0021543 42 0.014
negative regulation of metabolic process GO:0009892 331 0.014
involuntary skeletal muscle contraction GO:0003011 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
response to mercury ion GO:0046689 15 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
establishment of protein localization GO:0045184 141 0.014
positive regulation of nervous system development GO:0051962 178 0.014
regulation of neuron projection development GO:0010975 161 0.014
Mouse Rat
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.014
neuron development GO:0048666 286 0.014
Mouse Rat
neuron projection development GO:0031175 273 0.014
Mouse Rat
dibenzo p dioxin metabolic process GO:0018894 10 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
cellular response to reactive oxygen species GO:0034614 55 0.014
single organism intracellular transport GO:1902582 166 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
cyclic nucleotide biosynthetic process GO:0009190 63 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of cellular response to stress GO:0080135 49 0.014
Mouse
heart development GO:0007507 72 0.014
regulation of microtubule polymerization or depolymerization GO:0031110 12 0.014
positive regulation of map kinase activity GO:0043406 46 0.014
response to hydrogen peroxide GO:0042542 89 0.014
limbic system development GO:0021761 38 0.014
secretion by cell GO:0032940 248 0.014
ethanolamine containing compound metabolic process GO:0042439 14 0.014
vesicle mediated transport GO:0016192 181 0.014
hormone metabolic process GO:0042445 69 0.014
neuronal stem cell maintenance GO:0097150 2 0.014
regulation of transcription dna templated GO:0006355 374 0.014
positive regulation of transferase activity GO:0051347 81 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.014
hepaticobiliary system development GO:0061008 90 0.014
camp biosynthetic process GO:0006171 47 0.013
calcium ion transport GO:0006816 131 0.013
cardiac muscle tissue morphogenesis GO:0055008 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
gonad development GO:0008406 104 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
positive regulation of renin secretion into blood stream GO:1900135 1 0.013
cellular cation homeostasis GO:0030003 180 0.013
protein processing GO:0016485 68 0.013
metal ion transport GO:0030001 289 0.013
muscle tissue morphogenesis GO:0060415 1 0.013
atp metabolic process GO:0046034 72 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
response to tumor necrosis factor GO:0034612 56 0.013
reproductive structure development GO:0048608 128 0.013
positive regulation of nucleotide catabolic process GO:0030813 53 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
Mouse
response to testosterone GO:0033574 55 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
development of primary sexual characteristics GO:0045137 107 0.012
actin filament based process GO:0030029 86 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
single organism behavior GO:0044708 130 0.012
Mouse
nucleobase containing compound catabolic process GO:0034655 152 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
sex differentiation GO:0007548 113 0.012
ossification GO:0001503 70 0.012
respiratory system process GO:0003016 3 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
response to cadmium ion GO:0046686 35 0.012
response to monosaccharide GO:0034284 159 0.012
chemical homeostasis GO:0048878 292 0.012
cation transport GO:0006812 382 0.012
response to monoamine GO:0071867 17 0.012
cell growth GO:0016049 104 0.012
diaphragm contraction GO:0002086 2 0.012
rhythmic process GO:0048511 156 0.012
digestive system process GO:0022600 24 0.012
telencephalon development GO:0021537 62 0.011
negative regulation of nervous system development GO:0051961 79 0.011
Mouse
protein lipid complex remodeling GO:0034368 1 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
regulation of mapk cascade GO:0043408 116 0.011
negative regulation of neuron death GO:1901215 69 0.011
formation of primary germ layer GO:0001704 1 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
renin secretion into blood stream GO:0002001 1 0.011
positive regulation of developmental process GO:0051094 283 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
regulation of transferase activity GO:0051338 123 0.011
regulation of potassium ion transport GO:0043266 29 0.011
renal system process GO:0003014 40 0.011
response to glucose GO:0009749 136 0.011
tube development GO:0035295 89 0.011
protein localization to membrane GO:0072657 36 0.011
protein maturation GO:0051604 68 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.011
detection of temperature stimulus GO:0016048 4 0.011
salivary gland development GO:0007431 3 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
monocarboxylic acid transport GO:0015718 52 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
Mouse
cellular response to cytokine stimulus GO:0071345 127 0.011
response to cold GO:0009409 29 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
ras protein signal transduction GO:0007265 29 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of signal transduction GO:0009966 318 0.010
cellular response to oxygen levels GO:0071453 60 0.010
cognition GO:0050890 92 0.010
Mouse
positive regulation of cellular catabolic process GO:0031331 71 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
response to vitamin e GO:0033197 24 0.010
regulation of blood circulation GO:1903522 110 0.010
Rat
hair cell differentiation GO:0035315 2 0.010
gastrulation GO:0007369 2 0.010
urogenital system development GO:0001655 78 0.010

Klk8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.022
congenital adrenal hyperplasia DOID:0050811 0 0.019
disease of metabolism DOID:0014667 0 0.019
lipid metabolism disorder DOID:3146 0 0.019
inherited metabolic disorder DOID:655 0 0.019
steroid inherited metabolic disorder DOID:1701 0 0.019
muscular disease DOID:0080000 0 0.017
myopathy DOID:423 0 0.014
muscle tissue disease DOID:66 0 0.014
nervous system disease DOID:863 0 0.011