Rattus norvegicus

0 known processes

Pi16

peptidase inhibitor 16

Pi16 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.164
regulation of nucleic acid templated transcription GO:1903506 380 0.129
regulation of rna biosynthetic process GO:2001141 381 0.127
regulation of rna metabolic process GO:0051252 391 0.109
nucleic acid templated transcription GO:0097659 379 0.108
transcription from rna polymerase ii promoter GO:0006366 252 0.102
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.102
rna metabolic process GO:0016070 406 0.097
regulation of transcription dna templated GO:0006355 374 0.096
rna biosynthetic process GO:0032774 380 0.094
regeneration GO:0031099 163 0.092
regulation of programmed cell death GO:0043067 341 0.089
apoptotic process GO:0006915 381 0.085
response to hypoxia GO:0001666 231 0.085
cellular lipid metabolic process GO:0044255 208 0.072
programmed cell death GO:0012501 392 0.071
response to nutrient levels GO:0031667 370 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.068
organic acid metabolic process GO:0006082 292 0.067
positive regulation of cellular biosynthetic process GO:0031328 295 0.067
regulation of molecular function GO:0065009 398 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.064
positive regulation of cell proliferation GO:0008284 249 0.064
intracellular signal transduction GO:0035556 314 0.062
wound healing GO:0042060 122 0.058
reproductive process GO:0022414 372 0.055
Fly
response to wounding GO:0009611 254 0.054
catabolic process GO:0009056 351 0.054
regulation of signal transduction GO:0009966 318 0.054
regulation of catalytic activity GO:0050790 304 0.053
carboxylic acid metabolic process GO:0019752 289 0.053
negative regulation of cellular metabolic process GO:0031324 281 0.053
response to oxygen levels GO:0070482 265 0.052
response to corticosteroid GO:0031960 235 0.052
cellular response to endogenous stimulus GO:0071495 377 0.051
regulation of protein metabolic process GO:0051246 289 0.051
homeostatic process GO:0042592 331 0.051
regulation of apoptotic process GO:0042981 335 0.049
positive regulation of gene expression GO:0010628 244 0.048
response to decreased oxygen levels GO:0036293 237 0.047
aging GO:0007568 241 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
positive regulation of cell communication GO:0010647 271 0.046
single organism reproductive process GO:0044702 297 0.046
positive regulation of programmed cell death GO:0043068 157 0.046
oxidation reduction process GO:0055114 304 0.046
single organism biosynthetic process GO:0044711 342 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
proteolysis GO:0006508 175 0.043
cellular amine metabolic process GO:0044106 38 0.042
response to extracellular stimulus GO:0009991 380 0.042
cellular response to hormone stimulus GO:0032870 247 0.041
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.041
tissue development GO:0009888 252 0.041
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.041
reproduction GO:0000003 245 0.040
Fly
regulation of cell proliferation GO:0042127 359 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.039
positive regulation of molecular function GO:0044093 230 0.039
negative regulation of metabolic process GO:0009892 331 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.038
cellular response to oxygen containing compound GO:1901701 386 0.038
positive regulation of cell death GO:0010942 184 0.038
single organism catabolic process GO:0044712 283 0.038
organic substance catabolic process GO:1901575 316 0.037
multicellular organism reproduction GO:0032504 233 0.037
Fly
cellular amino acid metabolic process GO:0006520 107 0.037
cation transport GO:0006812 382 0.037
cellular catabolic process GO:0044248 295 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
positive regulation of transcription dna templated GO:0045893 197 0.036
metal ion transport GO:0030001 289 0.035
response to peptide hormone GO:0043434 278 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
cellular response to lipid GO:0071396 201 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
organophosphate metabolic process GO:0019637 370 0.034
positive regulation of rna metabolic process GO:0051254 203 0.034
regulation of phosphorylation GO:0042325 248 0.034
multi multicellular organism process GO:0044706 138 0.034
Fly
purine nucleotide metabolic process GO:0006163 229 0.034
lipid metabolic process GO:0006629 283 0.034
positive regulation of apoptotic process GO:0043065 154 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
single organism carbohydrate metabolic process GO:0044723 118 0.033
multi organism reproductive process GO:0044703 262 0.033
Fly
negative regulation of biosynthetic process GO:0009890 168 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.033
negative regulation of gene expression GO:0010629 199 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
response to inorganic substance GO:0010035 377 0.032
response to cytokine GO:0034097 215 0.032
dephosphorylation GO:0016311 98 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
cellular ketone metabolic process GO:0042180 51 0.031
response to acid chemical GO:0001101 222 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
Fly
oxoacid metabolic process GO:0043436 290 0.030
nucleotide metabolic process GO:0009117 279 0.030
peptidyl amino acid modification GO:0018193 126 0.030
purine containing compound metabolic process GO:0072521 253 0.030
response to biotic stimulus GO:0009607 226 0.029
chemical homeostasis GO:0048878 292 0.029
protein phosphorylation GO:0006468 345 0.029
cellular response to stress GO:0033554 269 0.029
lipid biosynthetic process GO:0008610 128 0.029
secretion GO:0046903 307 0.029
ras protein signal transduction GO:0007265 29 0.029
rhythmic process GO:0048511 156 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.028
Mouse
response to peptide GO:1901652 292 0.028
secretion by cell GO:0032940 248 0.028
positive regulation of signal transduction GO:0009967 175 0.028
regulation of system process GO:0044057 208 0.028
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of cellular component organization GO:0051128 368 0.027
Mouse
positive regulation of signaling GO:0023056 270 0.026
response to growth factor GO:0070848 189 0.026
growth GO:0040007 165 0.026
Mouse
response to glucocorticoid GO:0051384 223 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
sexual reproduction GO:0019953 148 0.025
Fly
purine nucleoside metabolic process GO:0042278 169 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
blood circulation GO:0008015 183 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.025
cellular response to alcohol GO:0097306 87 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
cellular component biogenesis GO:0044085 368 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
regulation of immune system process GO:0002682 123 0.024
negative regulation of cell communication GO:0010648 158 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
circadian rhythm GO:0007623 88 0.024
response to nutrient GO:0007584 248 0.024
response to monosaccharide GO:0034284 159 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
cellular component assembly GO:0022607 360 0.023
response to hexose GO:0009746 144 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
circulatory system development GO:0072359 134 0.023
Mouse
response to bacterium GO:0009617 200 0.023
response to glucose GO:0009749 136 0.023
negative regulation of molecular function GO:0044092 133 0.023
positive regulation of transport GO:0051050 245 0.023
neuron projection development GO:0031175 273 0.022
head development GO:0060322 247 0.022
localization of cell GO:0051674 202 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
regulation of secretion GO:0051046 224 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
cell growth GO:0016049 104 0.021
Mouse
response to mechanical stimulus GO:0009612 134 0.021
defense response GO:0006952 194 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
carbohydrate metabolic process GO:0005975 130 0.021
inflammatory response GO:0006954 150 0.020
negative regulation of signaling GO:0023057 157 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
amine metabolic process GO:0009308 38 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
gamete generation GO:0007276 124 0.020
regulation of transferase activity GO:0051338 123 0.020
positive regulation of cellular component movement GO:0051272 102 0.020
transmembrane transport GO:0055085 412 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
protein oligomerization GO:0051259 191 0.020
regulation of metal ion transport GO:0010959 118 0.020
neuron differentiation GO:0030182 368 0.020
mapk cascade GO:0000165 140 0.019
regulation of muscle system process GO:0090257 79 0.019
Mouse
response to estradiol GO:0032355 164 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
central nervous system development GO:0007417 311 0.019
organophosphate catabolic process GO:0046434 148 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
ion homeostasis GO:0050801 212 0.019
cellular homeostasis GO:0019725 252 0.019
regulation of inflammatory response GO:0050727 48 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
protein maturation GO:0051604 68 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
female pregnancy GO:0007565 122 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
nucleoside triphosphate catabolic process GO:0009143 123 0.018
response to carbohydrate GO:0009743 183 0.018
response to ketone GO:1901654 182 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
response to vitamin GO:0033273 131 0.018
cellular chemical homeostasis GO:0055082 247 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of response to external stimulus GO:0032101 106 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
transmission of nerve impulse GO:0019226 42 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
response to insulin GO:0032868 133 0.017
nucleoside metabolic process GO:0009116 179 0.017
muscle system process GO:0003012 115 0.017
Mouse
developmental growth GO:0048589 100 0.017
Mouse
purine ribonucleotide catabolic process GO:0009154 136 0.017
nucleoside catabolic process GO:0009164 126 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
taxis GO:0042330 67 0.017
protein complex subunit organization GO:0071822 302 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
establishment of protein localization GO:0045184 141 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
response to oxidative stress GO:0006979 186 0.016
anterior posterior pattern specification GO:0009952 1 0.016
biological adhesion GO:0022610 110 0.016
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.016
regulation of cell cycle GO:0051726 73 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
organelle organization GO:0006996 266 0.016
regulation of synaptic transmission GO:0050804 141 0.016
protein complex assembly GO:0006461 263 0.016
protein processing GO:0016485 68 0.016
cellular component morphogenesis GO:0032989 155 0.016
nitrogen compound transport GO:0071705 229 0.016
cellular response to steroid hormone stimulus GO:0071383 93 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
cellular response to external stimulus GO:0071496 118 0.016
cell projection organization GO:0030030 302 0.016
response to lipopolysaccharide GO:0032496 191 0.015
monosaccharide metabolic process GO:0005996 61 0.015
cell motility GO:0048870 202 0.015
heterocycle catabolic process GO:0046700 167 0.015
tissue remodeling GO:0048771 40 0.015
regulation of response to wounding GO:1903034 69 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
renal system development GO:0072001 67 0.015
nucleotide catabolic process GO:0009166 139 0.015
regulation of protein maturation GO:1903317 50 0.015
calcium ion transport GO:0006816 131 0.015
negative regulation of cell death GO:0060548 229 0.015
regulation of blood circulation GO:1903522 110 0.015
regulation of cell differentiation GO:0045595 320 0.015
Mouse
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
cellular cation homeostasis GO:0030003 180 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
positive regulation of mapk cascade GO:0043410 92 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
regulation of nervous system development GO:0051960 264 0.014
striated muscle tissue development GO:0014706 58 0.014
Mouse
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
regulation of secretion by cell GO:1903530 208 0.014
neurological system process GO:0050877 219 0.014
neuron development GO:0048666 286 0.014
positive regulation of cell migration GO:0030335 96 0.014
cell cycle checkpoint GO:0000075 2 0.014
muscle cell proliferation GO:0033002 84 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of kinase activity GO:0043549 117 0.014
response to metal ion GO:0010038 253 0.014
cell cycle GO:0007049 101 0.014
cellular component movement GO:0006928 248 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
positive regulation of cell motility GO:2000147 97 0.013
vesicle mediated transport GO:0016192 181 0.013
heart development GO:0007507 72 0.013
Mouse
regulation of cell growth GO:0001558 85 0.013
Mouse
positive regulation of cellular component organization GO:0051130 200 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
organ regeneration GO:0031100 101 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
single organism organelle organization GO:1902589 180 0.013
response to external biotic stimulus GO:0043207 221 0.013
protein localization GO:0008104 191 0.013
positive regulation of transferase activity GO:0051347 81 0.013
positive regulation of protein modification process GO:0031401 142 0.013
negative regulation of developmental process GO:0051093 125 0.013
Mouse
metal ion homeostasis GO:0055065 186 0.013
heart morphogenesis GO:0003007 3 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
divalent inorganic cation transport GO:0072511 134 0.013
regulation of cellular component movement GO:0051270 150 0.013
synaptic transmission GO:0007268 235 0.013
multicellular organismal signaling GO:0035637 44 0.013
cardiac chamber development GO:0003205 1 0.013
regulation of proteolysis GO:0030162 66 0.012
regulation of ion transport GO:0043269 245 0.012
cell migration GO:0016477 197 0.012
cell adhesion GO:0007155 110 0.012
Rat
glucose metabolic process GO:0006006 52 0.012
immune effector process GO:0002252 53 0.012
regulation of cell development GO:0060284 263 0.012
Mouse
muscle structure development GO:0061061 87 0.012
Mouse
regulation of hydrolase activity GO:0051336 143 0.012
limb morphogenesis GO:0035108 4 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
cell cell signaling GO:0007267 335 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
kidney development GO:0001822 67 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
Rat
positive regulation of secretion by cell GO:1903532 128 0.012
regulation of g0 to g1 transition GO:0070316 3 0.012
regulation of cell adhesion GO:0030155 52 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
negative regulation of protein maturation GO:1903318 47 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
cytoskeleton organization GO:0007010 111 0.012
brain development GO:0007420 247 0.012
regulation of neurogenesis GO:0050767 247 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
small molecule biosynthetic process GO:0044283 124 0.012
divalent metal ion transport GO:0070838 132 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
epithelium development GO:0060429 96 0.011
spermatogenesis GO:0007283 99 0.011
salivary gland development GO:0007431 3 0.011
embryonic limb morphogenesis GO:0030326 4 0.011
response to estrogen GO:0043627 232 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
tissue regeneration GO:0042246 36 0.011
embryonic pattern specification GO:0009880 1 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
acute inflammatory response GO:0002526 58 0.011
response to temperature stimulus GO:0009266 94 0.011
developmental induction GO:0031128 2 0.011
aromatic compound catabolic process GO:0019439 168 0.011
macromolecular complex assembly GO:0065003 273 0.011
hexose metabolic process GO:0019318 58 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
urogenital system development GO:0001655 78 0.011
ion transmembrane transport GO:0034220 365 0.011
regulation of catabolic process GO:0009894 113 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
cellular protein localization GO:0034613 122 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
regulation of membrane potential GO:0042391 110 0.011
response to increased oxygen levels GO:0036296 45 0.011
cation transmembrane transport GO:0098655 263 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
response to ethanol GO:0045471 162 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
axis specification GO:0009798 4 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
negative regulation of transport GO:0051051 136 0.011
positive regulation of locomotion GO:0040017 102 0.011
regulation of body fluid levels GO:0050878 90 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of protein processing GO:0010955 47 0.011
developmental process involved in reproduction GO:0003006 159 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of response to stress GO:0080134 126 0.011
positive regulation of kinase activity GO:0033674 77 0.011
regulation of neuron projection development GO:0010975 161 0.011
regulation of protein processing GO:0070613 50 0.010
regulation of protein modification process GO:0031399 194 0.010
protein complex biogenesis GO:0070271 263 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
fertilization GO:0009566 3 0.010
cell cycle process GO:0022402 57 0.010
negative regulation of signal transduction GO:0009968 83 0.010
sodium ion transport GO:0006814 82 0.010
glucose homeostasis GO:0042593 75 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010
regulation of neuron differentiation GO:0045664 208 0.010
regulation of anatomical structure size GO:0090066 135 0.010
regulation of cytokine production GO:0001817 56 0.010
male gamete generation GO:0048232 99 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
potassium ion transport GO:0006813 97 0.010

Pi16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
bone disease DOID:0080001 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011