Rattus norvegicus

0 known processes

Me3

malic enzyme 3, NADP(+)-dependent, mitochondrial

Me3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to stress GO:0033554 269 0.058
regulation of cell proliferation GO:0042127 359 0.058
transmembrane transport GO:0055085 412 0.055
response to estrogen GO:0043627 232 0.055
heart contraction GO:0060047 57 0.054
anatomical structure morphogenesis GO:0009653 298 0.050
blood circulation GO:0008015 183 0.046
oxoacid metabolic process GO:0043436 290 0.045
Human
response to inorganic substance GO:0010035 377 0.044
neuron projection development GO:0031175 273 0.041
inorganic cation transmembrane transport GO:0098662 202 0.040
central nervous system development GO:0007417 311 0.039
muscle contraction GO:0006936 88 0.037
positive regulation of cell proliferation GO:0008284 249 0.036
cellular response to endogenous stimulus GO:0071495 377 0.036
response to glucocorticoid GO:0051384 223 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
neuron differentiation GO:0030182 368 0.035
regulation of cellular component organization GO:0051128 368 0.034
inorganic ion transmembrane transport GO:0098660 229 0.034
regulation of molecular function GO:0065009 398 0.033
neuron development GO:0048666 286 0.033
response to decreased oxygen levels GO:0036293 237 0.033
cellular response to hormone stimulus GO:0032870 247 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.032
protein complex biogenesis GO:0070271 263 0.032
cellular response to organic cyclic compound GO:0071407 202 0.032
apoptotic process GO:0006915 381 0.031
carbohydrate metabolic process GO:0005975 130 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
regulation of apoptotic process GO:0042981 335 0.030
amine metabolic process GO:0009308 38 0.030
nucleic acid templated transcription GO:0097659 379 0.030
response to ethanol GO:0045471 162 0.030
single organism biosynthetic process GO:0044711 342 0.029
regulation of cellular localization GO:0060341 263 0.029
regulation of cell differentiation GO:0045595 320 0.028
regulation of ion transport GO:0043269 245 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
metal ion transport GO:0030001 289 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
macromolecular complex subunit organization GO:0043933 339 0.026
response to estradiol GO:0032355 164 0.026
regulation of programmed cell death GO:0043067 341 0.026
negative regulation of metabolic process GO:0009892 331 0.025
cell projection organization GO:0030030 302 0.025
cellular amine metabolic process GO:0044106 38 0.025
secretion GO:0046903 307 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
Human
heart process GO:0003015 57 0.023
cation transport GO:0006812 382 0.023
response to insulin GO:0032868 133 0.023
nucleoside monophosphate metabolic process GO:0009123 93 0.023
regulation of membrane repolarization GO:0060306 1 0.023
regulation of neuron projection development GO:0010975 161 0.022
response to peptide hormone GO:0043434 278 0.022
cellular response to external stimulus GO:0071496 118 0.022
response to reactive oxygen species GO:0000302 120 0.022
rna metabolic process GO:0016070 406 0.022
response to wounding GO:0009611 254 0.022
negative regulation of cell communication GO:0010648 158 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
protein phosphorylation GO:0006468 345 0.022
muscle system process GO:0003012 115 0.022
response to ketone GO:1901654 182 0.022
neurological system process GO:0050877 219 0.022
regulation of rna metabolic process GO:0051252 391 0.022
regulation of synaptic transmission GO:0050804 141 0.022
transcription dna templated GO:0006351 377 0.021
programmed cell death GO:0012501 392 0.021
positive regulation of developmental process GO:0051094 283 0.021
negative regulation of transport GO:0051051 136 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.020
regulation of secretion by cell GO:1903530 208 0.020
homeostatic process GO:0042592 331 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
monovalent inorganic cation transport GO:0015672 172 0.019
protein complex subunit organization GO:0071822 302 0.019
action potential GO:0001508 54 0.019
intracellular signal transduction GO:0035556 314 0.019
regulation of phosphorylation GO:0042325 248 0.019
ribonucleoside monophosphate metabolic process GO:0009161 88 0.019
regulation of cell development GO:0060284 263 0.019
purine nucleoside monophosphate catabolic process GO:0009128 55 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of protein metabolic process GO:0051246 289 0.019
response to metal ion GO:0010038 253 0.019
positive regulation of cell death GO:0010942 184 0.019
head development GO:0060322 247 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
response to peptide GO:1901652 292 0.018
macromolecular complex assembly GO:0065003 273 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
response to extracellular stimulus GO:0009991 380 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
response to nutrient levels GO:0031667 370 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
macromolecule localization GO:0033036 252 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
single organism behavior GO:0044708 130 0.017
negative regulation of signaling GO:0023057 157 0.017
regulation of transcription dna templated GO:0006355 374 0.017
membrane repolarization GO:0086009 1 0.017
cellular component biogenesis GO:0044085 368 0.017
cellular chemical homeostasis GO:0055082 247 0.017
regulation of homeostatic process GO:0032844 101 0.017
cardiac muscle cell contraction GO:0086003 10 0.017
cation transmembrane transport GO:0098655 263 0.017
regeneration GO:0031099 163 0.017
organophosphate metabolic process GO:0019637 370 0.017
cellular ketone metabolic process GO:0042180 51 0.017
negative regulation of neuron differentiation GO:0045665 62 0.017
organic acid metabolic process GO:0006082 292 0.017
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
nucleotide catabolic process GO:0009166 139 0.017
negative regulation of molecular function GO:0044092 133 0.017
cellular component morphogenesis GO:0032989 155 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
intracellular transport GO:0046907 185 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
regulation of metal ion transport GO:0010959 118 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
cellular component movement GO:0006928 248 0.016
generation of precursor metabolites and energy GO:0006091 62 0.016
cellular response to insulin stimulus GO:0032869 81 0.016
response to acid chemical GO:0001101 222 0.016
behavior GO:0007610 205 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
regulation of catabolic process GO:0009894 113 0.016
cellular response to lipid GO:0071396 201 0.016
cardiac muscle contraction GO:0060048 27 0.016
purine containing compound metabolic process GO:0072521 253 0.016
positive regulation of transport GO:0051050 245 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
response to hypoxia GO:0001666 231 0.015
negative regulation of protein import into nucleus translocation GO:0033159 1 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
protein complex assembly GO:0006461 263 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
single organism catabolic process GO:0044712 283 0.015
rna biosynthetic process GO:0032774 380 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
regulation of cell projection organization GO:0031344 175 0.015
regulation of neurogenesis GO:0050767 247 0.015
organelle organization GO:0006996 266 0.015
regulation of membrane potential GO:0042391 110 0.015
growth GO:0040007 165 0.015
chemical homeostasis GO:0048878 292 0.015
response to oxygen levels GO:0070482 265 0.015
response to corticosteroid GO:0031960 235 0.015
regulation of dna metabolic process GO:0051052 60 0.015
protein oligomerization GO:0051259 191 0.014
l glutamate import GO:0051938 2 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
response to testosterone GO:0033574 55 0.014
cell cycle GO:0007049 101 0.014
reproductive process GO:0022414 372 0.014
anion transport GO:0006820 178 0.014
positive regulation of molecular function GO:0044093 230 0.014
positive regulation of signaling GO:0023056 270 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
response to monosaccharide GO:0034284 159 0.014
ion transmembrane transport GO:0034220 365 0.014
negative regulation of developmental process GO:0051093 125 0.014
response to hydrogen peroxide GO:0042542 89 0.014
cell communication involved in cardiac conduction GO:0086065 2 0.013
regulation of nervous system development GO:0051960 264 0.013
lipid storage GO:0019915 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
sodium ion transport GO:0006814 82 0.013
circulatory system process GO:0003013 183 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
cell growth GO:0016049 104 0.013
cellular homeostasis GO:0019725 252 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
response to glucose GO:0009749 136 0.013
muscle structure development GO:0061061 87 0.013
reproductive system development GO:0061458 128 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
cell adhesion GO:0007155 110 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
aging GO:0007568 241 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
potassium ion transmembrane transport GO:0071805 71 0.013
single organism cellular localization GO:1902580 102 0.013
nucleoside metabolic process GO:0009116 179 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
cation homeostasis GO:0055080 195 0.013
negative regulation of gene expression GO:0010629 199 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.012
regulation of cell growth GO:0001558 85 0.012
response to temperature stimulus GO:0009266 94 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
calcium ion transport GO:0006816 131 0.012
regulation of protein transport GO:0051223 68 0.012
regulation of catalytic activity GO:0050790 304 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
renal system development GO:0072001 67 0.012
gland development GO:0048732 155 0.012
tube development GO:0035295 89 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
Human
energy derivation by oxidation of organic compounds GO:0015980 46 0.012
regulation of protein modification process GO:0031399 194 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
potassium ion transport GO:0006813 97 0.011
regulation of signal transduction GO:0009966 318 0.011
regulation of peptide transport GO:0090087 87 0.011
response to hexose GO:0009746 144 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
cellular ion homeostasis GO:0006873 184 0.011
catabolic process GO:0009056 351 0.011
response to starvation GO:0042594 59 0.011
cellular cation homeostasis GO:0030003 180 0.011
nucleotide metabolic process GO:0009117 279 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
kidney development GO:0001822 67 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
glucose homeostasis GO:0042593 75 0.011
purine containing compound catabolic process GO:0072523 138 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
response to cytokine GO:0034097 215 0.011
peptidyl amino acid modification GO:0018193 126 0.011
chemosensory behavior GO:0007635 2 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
cell cell signaling GO:0007267 335 0.011
axis specification GO:0009798 4 0.011
regulation of neuron differentiation GO:0045664 208 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
cellular catabolic process GO:0044248 295 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
regulation of transmembrane transport GO:0034762 122 0.011
cytoplasmic transport GO:0016482 115 0.011
ras protein signal transduction GO:0007265 29 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
actin mediated cell contraction GO:0070252 12 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
nitrogen compound transport GO:0071705 229 0.010
maintenance of location GO:0051235 17 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
regulation of actin filament based process GO:0032970 42 0.010
aromatic compound catabolic process GO:0019439 168 0.010
regulation of system process GO:0044057 208 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
heart morphogenesis GO:0003007 3 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
muscle cell proliferation GO:0033002 84 0.010
tissue development GO:0009888 252 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
regulation of protein localization GO:0032880 81 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.010
protein heterooligomerization GO:0051291 89 0.010

Me3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
long qt syndrome DOID:2843 0 0.037