Rattus norvegicus

0 known processes

Tmem136

transmembrane protein 136

(Aliases: RGD1565079)

Tmem136 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule localization GO:0033036 252 0.083
organic acid metabolic process GO:0006082 292 0.076
regulation of phosphate metabolic process GO:0019220 349 0.074
regulation of rna biosynthetic process GO:2001141 381 0.071
secretion GO:0046903 307 0.065
regulation of phosphorus metabolic process GO:0051174 349 0.064
carboxylic acid metabolic process GO:0019752 289 0.060
intracellular transport GO:0046907 185 0.059
intracellular signal transduction GO:0035556 314 0.057
response to oxygen levels GO:0070482 265 0.056
negative regulation of metabolic process GO:0009892 331 0.056
regulation of molecular function GO:0065009 398 0.054
cellular response to oxygen containing compound GO:1901701 386 0.053
cellular catabolic process GO:0044248 295 0.053
cellular component biogenesis GO:0044085 368 0.052
cellular amino acid metabolic process GO:0006520 107 0.052
regulation of cell differentiation GO:0045595 320 0.052
cellular response to endogenous stimulus GO:0071495 377 0.050
response to peptide GO:1901652 292 0.050
localization of cell GO:0051674 202 0.050
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
protein complex subunit organization GO:0071822 302 0.049
regulation of transcription dna templated GO:0006355 374 0.049
response to decreased oxygen levels GO:0036293 237 0.048
negative regulation of cellular metabolic process GO:0031324 281 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
cation transport GO:0006812 382 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.045
reproductive process GO:0022414 372 0.045
cellular component assembly GO:0022607 360 0.044
organophosphate metabolic process GO:0019637 370 0.043
cell projection organization GO:0030030 302 0.043
neuron development GO:0048666 286 0.042
oxoacid metabolic process GO:0043436 290 0.042
rna biosynthetic process GO:0032774 380 0.042
positive regulation of cellular protein metabolic process GO:0032270 167 0.041
regulation of cellular localization GO:0060341 263 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
organic substance catabolic process GO:1901575 316 0.041
rna metabolic process GO:0016070 406 0.041
positive regulation of developmental process GO:0051094 283 0.040
regulation of cell development GO:0060284 263 0.040
positive regulation of cell differentiation GO:0045597 217 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.040
regulation of hormone levels GO:0010817 187 0.039
neuron differentiation GO:0030182 368 0.039
cellular divalent inorganic cation homeostasis GO:0072503 162 0.039
neuron projection development GO:0031175 273 0.039
regulation of cell proliferation GO:0042127 359 0.038
cellular component movement GO:0006928 248 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
multicellular organism reproduction GO:0032504 233 0.037
transcription dna templated GO:0006351 377 0.037
head development GO:0060322 247 0.037
regulation of phosphorylation GO:0042325 248 0.037
positive regulation of response to stimulus GO:0048584 285 0.036
protein phosphorylation GO:0006468 345 0.036
response to hypoxia GO:0001666 231 0.036
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
positive regulation of cell proliferation GO:0008284 249 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
catabolic process GO:0009056 351 0.036
cation homeostasis GO:0055080 195 0.035
cell migration GO:0016477 197 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
positive regulation of phosphorus metabolic process GO:0010562 262 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.035
nucleic acid templated transcription GO:0097659 379 0.035
positive regulation of molecular function GO:0044093 230 0.035
homeostatic process GO:0042592 331 0.035
regulation of catalytic activity GO:0050790 304 0.034
single organism intracellular transport GO:1902582 166 0.034
protein oligomerization GO:0051259 191 0.034
regulation of signal transduction GO:0009966 318 0.034
regulation of protein metabolic process GO:0051246 289 0.034
protein localization GO:0008104 191 0.034
cell motility GO:0048870 202 0.033
cellular amine metabolic process GO:0044106 38 0.033
appendage morphogenesis GO:0035107 4 0.033
positive regulation of gene expression GO:0010628 244 0.033
response to metal ion GO:0010038 253 0.032
locomotion GO:0040011 237 0.032
positive regulation of nucleic acid templated transcription GO:1903508 197 0.032
single organism biosynthetic process GO:0044711 342 0.032
multi organism reproductive process GO:0044703 262 0.032
cellular ketone metabolic process GO:0042180 51 0.032
response to estrogen GO:0043627 232 0.032
regulation of cellular component organization GO:0051128 368 0.032
secretion by cell GO:0032940 248 0.031
amine metabolic process GO:0009308 38 0.031
regulation of rna metabolic process GO:0051252 391 0.031
reproduction GO:0000003 245 0.031
cytosolic calcium ion homeostasis GO:0051480 140 0.031
regulation of secretion GO:0051046 224 0.031
response to inorganic substance GO:0010035 377 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
regulation of apoptotic process GO:0042981 335 0.030
cellular cation homeostasis GO:0030003 180 0.030
cellular metal ion homeostasis GO:0006875 172 0.030
regulation of nervous system development GO:0051960 264 0.030
cellular response to hormone stimulus GO:0032870 247 0.030
apoptotic process GO:0006915 381 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.029
regulation of neurogenesis GO:0050767 247 0.029
regulation of protein modification process GO:0031399 194 0.029
central nervous system development GO:0007417 311 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
single organism catabolic process GO:0044712 283 0.028
response to acid chemical GO:0001101 222 0.028
organic acid transport GO:0015849 116 0.028
single organism reproductive process GO:0044702 297 0.028
chemical homeostasis GO:0048878 292 0.028
tissue development GO:0009888 252 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
negative regulation of transport GO:0051051 136 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
metal ion transport GO:0030001 289 0.027
response to extracellular stimulus GO:0009991 380 0.026
regulation of neuron differentiation GO:0045664 208 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
proteolysis GO:0006508 175 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
metal ion homeostasis GO:0055065 186 0.026
negative regulation of gene expression GO:0010629 199 0.026
purine nucleotide metabolic process GO:0006163 229 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
protein transport GO:0015031 132 0.025
positive regulation of cell communication GO:0010647 271 0.025
purine containing compound metabolic process GO:0072521 253 0.025
positive regulation of signaling GO:0023056 270 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
response to nutrient levels GO:0031667 370 0.025
maintenance of location GO:0051235 17 0.025
cellular macromolecule localization GO:0070727 122 0.025
cardiac chamber development GO:0003205 1 0.025
regulation of cellular component movement GO:0051270 150 0.025
regulation of cell projection organization GO:0031344 175 0.025
lipid metabolic process GO:0006629 283 0.025
negative regulation of cell communication GO:0010648 158 0.025
cell projection morphogenesis GO:0048858 123 0.024
cellular homeostasis GO:0019725 252 0.024
cellular response to stress GO:0033554 269 0.024
cellular chemical homeostasis GO:0055082 247 0.024
response to growth factor GO:0070848 189 0.024
carboxylic acid transport GO:0046942 115 0.024
organelle organization GO:0006996 266 0.024
limb morphogenesis GO:0035108 4 0.024
nitrogen compound transport GO:0071705 229 0.024
aging GO:0007568 241 0.023
cellular protein localization GO:0034613 122 0.023
peptidyl amino acid modification GO:0018193 126 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
nucleotide metabolic process GO:0009117 279 0.023
positive regulation of protein modification process GO:0031401 142 0.023
regulation of secretion by cell GO:1903530 208 0.023
immune system process GO:0002376 204 0.023
single organism organelle organization GO:1902589 180 0.023
embryonic skeletal system morphogenesis GO:0048704 3 0.022
organophosphate biosynthetic process GO:0090407 143 0.022
establishment of protein localization GO:0045184 141 0.022
programmed cell death GO:0012501 392 0.022
organ morphogenesis GO:0009887 75 0.022
cellular response to lipid GO:0071396 201 0.022
brain development GO:0007420 247 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
ras protein signal transduction GO:0007265 29 0.022
negative regulation of signaling GO:0023057 157 0.022
cellular ion homeostasis GO:0006873 184 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
ion homeostasis GO:0050801 212 0.021
response to peptide hormone GO:0043434 278 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
macromolecular complex assembly GO:0065003 273 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
protein complex assembly GO:0006461 263 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
negative regulation of signal transduction GO:0009968 83 0.021
calcium ion homeostasis GO:0055074 162 0.020
negative regulation of developmental process GO:0051093 125 0.020
response to corticosteroid GO:0031960 235 0.020
regulation of locomotion GO:0040012 148 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
heart morphogenesis GO:0003007 3 0.020
regulation of ion transport GO:0043269 245 0.020
synaptic transmission GO:0007268 235 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
cell part morphogenesis GO:0032990 123 0.019
protein complex biogenesis GO:0070271 263 0.019
transmembrane transport GO:0055085 412 0.019
response to wounding GO:0009611 254 0.019
negative regulation of nervous system development GO:0051961 79 0.019
sexual reproduction GO:0019953 148 0.019
regulation of kinase activity GO:0043549 117 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
muscle structure development GO:0061061 87 0.019
cellular response to peptide GO:1901653 133 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.018
response to bacterium GO:0009617 200 0.018
hormone transport GO:0009914 121 0.018
cell morphogenesis GO:0000902 142 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
response to external biotic stimulus GO:0043207 221 0.018
axon development GO:0061564 96 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
cation transmembrane transport GO:0098655 263 0.018
cytoplasmic transport GO:0016482 115 0.018
defense response GO:0006952 194 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
cell cell signaling GO:0007267 335 0.018
positive regulation of cell death GO:0010942 184 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
regulation of cell motility GO:2000145 131 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
gland development GO:0048732 155 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
response to other organism GO:0051707 220 0.017
organic anion transport GO:0015711 132 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
positive regulation of catalytic activity GO:0043085 184 0.016
response to glucocorticoid GO:0051384 223 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
vesicle mediated transport GO:0016192 181 0.016
embryonic appendage morphogenesis GO:0035113 4 0.016
neural crest cell development GO:0014032 2 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
regulation of programmed cell death GO:0043067 341 0.016
eye morphogenesis GO:0048592 4 0.016
embryonic limb morphogenesis GO:0030326 4 0.016
reproductive system development GO:0061458 128 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
regulation of hormone secretion GO:0046883 106 0.016
regulation of protein kinase activity GO:0045859 105 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
regeneration GO:0031099 163 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
neural crest cell differentiation GO:0014033 2 0.015
response to nutrient GO:0007584 248 0.015
response to carbohydrate GO:0009743 183 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
positive regulation of cell migration GO:0030335 96 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of stem cell differentiation GO:2000736 2 0.015
ion transmembrane transport GO:0034220 365 0.015
positive regulation of transport GO:0051050 245 0.015
circulatory system development GO:0072359 134 0.015
cellular response to external stimulus GO:0071496 118 0.015
axis specification GO:0009798 4 0.015
gamete generation GO:0007276 124 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
blood circulation GO:0008015 183 0.015
gastrulation GO:0007369 2 0.015
calcium ion transport GO:0006816 131 0.015
response to fatty acid GO:0070542 65 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
reproductive structure development GO:0048608 128 0.014
cardiac ventricle development GO:0003231 1 0.014
neurological system process GO:0050877 219 0.014
positive regulation of cell development GO:0010720 176 0.014
positive regulation of cell motility GO:2000147 97 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
regulation of homeostatic process GO:0032844 101 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
cellular lipid metabolic process GO:0044255 208 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
response to estradiol GO:0032355 164 0.014
cell adhesion GO:0007155 110 0.014
response to glucose GO:0009749 136 0.014
divalent metal ion transport GO:0070838 132 0.014
protein homooligomerization GO:0051260 91 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
response to biotic stimulus GO:0009607 226 0.014
action potential GO:0001508 54 0.014
small molecule biosynthetic process GO:0044283 124 0.014
organophosphate catabolic process GO:0046434 148 0.014
negative regulation of cell differentiation GO:0045596 99 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
positive regulation of nervous system development GO:0051962 178 0.013
response to ammonium ion GO:0060359 71 0.013
hormone secretion GO:0046879 115 0.013
negative regulation of molecular function GO:0044092 133 0.013
peptide hormone secretion GO:0030072 84 0.013
lipid biosynthetic process GO:0008610 128 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
bmp signaling pathway GO:0030509 4 0.013
regulation of membrane potential GO:0042391 110 0.013
negative regulation of cell death GO:0060548 229 0.013
regulation of cell migration GO:0030334 128 0.013
response to cytokine GO:0034097 215 0.013
epithelium development GO:0060429 96 0.013
single organism cellular localization GO:1902580 102 0.013
sequestering of metal ion GO:0051238 9 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
regulation of mapk cascade GO:0043408 116 0.013
heart development GO:0007507 72 0.013
regulation of transferase activity GO:0051338 123 0.013
cell cycle GO:0007049 101 0.013
regulation of system process GO:0044057 208 0.013
amino acid transport GO:0006865 70 0.013
neuron projection morphogenesis GO:0048812 122 0.013
positive regulation of immune system process GO:0002684 90 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
regulation of neuron death GO:1901214 115 0.013
developmental process involved in reproduction GO:0003006 159 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
lipid transport GO:0006869 61 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
heterocycle catabolic process GO:0046700 167 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
negative regulation of cell development GO:0010721 82 0.012
nucleoside metabolic process GO:0009116 179 0.012
nuclear transport GO:0051169 49 0.012
spermatogenesis GO:0007283 99 0.012
oligopeptide transport GO:0006857 4 0.012
axon guidance GO:0007411 24 0.012
tube development GO:0035295 89 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
multi multicellular organism process GO:0044706 138 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
development of primary sexual characteristics GO:0045137 107 0.012
endocytosis GO:0006897 84 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
regulation of body fluid levels GO:0050878 90 0.012
rhythmic process GO:0048511 156 0.012
sex differentiation GO:0007548 113 0.012
embryonic skeletal system development GO:0048706 3 0.012
mesoderm development GO:0007498 2 0.011
actin filament based process GO:0030029 86 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
circulatory system process GO:0003013 183 0.011
positive regulation of neuron migration GO:2001224 2 0.011
amide transport GO:0042886 105 0.011
regulation of neuron projection development GO:0010975 161 0.011
response to alkaloid GO:0043279 132 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
neural crest cell migration GO:0001755 1 0.011
cytoskeleton organization GO:0007010 111 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of hydrolase activity GO:0051336 143 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of catabolic process GO:0009894 113 0.011
sequestering of calcium ion GO:0051208 8 0.011
response to oxidative stress GO:0006979 186 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to monosaccharide GO:0034284 159 0.011
divalent inorganic cation transport GO:0072511 134 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
regulation of response to stress GO:0080134 126 0.011
male gamete generation GO:0048232 99 0.011
chemosensory behavior GO:0007635 2 0.011
growth GO:0040007 165 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
response to vitamin GO:0033273 131 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of protein localization GO:0032880 81 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
peptide transport GO:0015833 97 0.011
organic hydroxy compound transport GO:0015850 77 0.011
cellular component morphogenesis GO:0032989 155 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
positive regulation of kinase activity GO:0033674 77 0.010
protein localization to organelle GO:0033365 57 0.010
protein heterooligomerization GO:0051291 89 0.010
rho protein signal transduction GO:0007266 11 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
tissue morphogenesis GO:0048729 22 0.010
sulfur compound metabolic process GO:0006790 70 0.010
regulation of intracellular transport GO:0032386 65 0.010
regulation of protein transport GO:0051223 68 0.010
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 3 0.010
response to reactive oxygen species GO:0000302 120 0.010
response to axon injury GO:0048678 59 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
response to mechanical stimulus GO:0009612 134 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
response to hexose GO:0009746 144 0.010
mapk cascade GO:0000165 140 0.010
neuron death GO:0070997 127 0.010
establishment of tissue polarity GO:0007164 2 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
biological adhesion GO:0022610 110 0.010
negative regulation of secretion GO:0051048 82 0.010
intracellular protein transport GO:0006886 79 0.010

Tmem136 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
musculoskeletal system disease DOID:17 0 0.015
cardiovascular system disease DOID:1287 0 0.012
muscular disease DOID:0080000 0 0.011
retinal disease DOID:5679 0 0.011
muscle tissue disease DOID:66 0 0.010