Rattus norvegicus

0 known processes

Arfgap1

ADP-ribosylation factor GTPase activating protein 1

(Aliases: Arf1gap,Arf GAP1)

Arfgap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.099
nucleotide metabolic process GO:0009117 279 0.095
cell cell signaling GO:0007267 335 0.085
regulation of multicellular organismal development GO:2000026 376 0.079
nucleoside phosphate metabolic process GO:0006753 283 0.075
neuron differentiation GO:0030182 368 0.074
negative regulation of multicellular organismal process GO:0051241 203 0.071
rna biosynthetic process GO:0032774 380 0.068
purine nucleotide metabolic process GO:0006163 229 0.065
nucleobase containing small molecule metabolic process GO:0055086 316 0.062
cellular catabolic process GO:0044248 295 0.062
ribose phosphate metabolic process GO:0019693 235 0.058
secretion GO:0046903 307 0.058
carbohydrate derivative metabolic process GO:1901135 346 0.057
ribonucleotide metabolic process GO:0009259 231 0.057
secretion by cell GO:0032940 248 0.053
positive regulation of biosynthetic process GO:0009891 319 0.052
synaptic transmission GO:0007268 235 0.051
organophosphate metabolic process GO:0019637 370 0.050
positive regulation of transport GO:0051050 245 0.050
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
organonitrogen compound biosynthetic process GO:1901566 167 0.047
cellular response to oxygen containing compound GO:1901701 386 0.047
regulation of locomotion GO:0040012 148 0.047
negative regulation of metabolic process GO:0009892 331 0.046
cellular component movement GO:0006928 248 0.046
protein complex assembly GO:0006461 263 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.046
cation transport GO:0006812 382 0.044
regulation of cell differentiation GO:0045595 320 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.042
transcription dna templated GO:0006351 377 0.042
organophosphate biosynthetic process GO:0090407 143 0.042
organonitrogen compound catabolic process GO:1901565 179 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
negative regulation of rna biosynthetic process GO:1902679 118 0.041
cellular calcium ion homeostasis GO:0006874 160 0.040
regulation of rna metabolic process GO:0051252 391 0.040
neuron projection development GO:0031175 273 0.039
response to inorganic substance GO:0010035 377 0.039
organic substance catabolic process GO:1901575 316 0.039
regulation of neuron differentiation GO:0045664 208 0.039
regulation of cellular component organization GO:0051128 368 0.038
neuron development GO:0048666 286 0.038
heterocycle catabolic process GO:0046700 167 0.037
macromolecular complex assembly GO:0065003 273 0.037
intracellular transport GO:0046907 185 0.036
ribonucleoside metabolic process GO:0009119 174 0.036
metal ion homeostasis GO:0055065 186 0.035
divalent inorganic cation homeostasis GO:0072507 165 0.035
cellular divalent inorganic cation homeostasis GO:0072503 162 0.035
b cell activation involved in immune response GO:0002312 1 0.035
response to extracellular stimulus GO:0009991 380 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
cellular metal ion homeostasis GO:0006875 172 0.034
response to carbohydrate GO:0009743 183 0.034
cell projection organization GO:0030030 302 0.034
calcium ion homeostasis GO:0055074 162 0.034
negative regulation of nervous system development GO:0051961 79 0.034
nucleic acid templated transcription GO:0097659 379 0.034
homeostatic process GO:0042592 331 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
cellular homeostasis GO:0019725 252 0.033
nucleoside triphosphate metabolic process GO:0009141 144 0.033
regulation of neurogenesis GO:0050767 247 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
vesicle mediated transport GO:0016192 181 0.032
response to oxygen levels GO:0070482 265 0.032
regulation of nucleotide metabolic process GO:0006140 117 0.032
cellular component assembly GO:0022607 360 0.032
blood circulation GO:0008015 183 0.031
regulation of cell migration GO:0030334 128 0.031
purine nucleotide biosynthetic process GO:0006164 83 0.030
carbohydrate derivative biosynthetic process GO:1901137 124 0.030
reproductive process GO:0022414 372 0.030
regulation of molecular function GO:0065009 398 0.030
regulation of neuron projection development GO:0010975 161 0.030
cellular component biogenesis GO:0044085 368 0.030
nucleoside phosphate biosynthetic process GO:1901293 102 0.030
rna metabolic process GO:0016070 406 0.030
circulatory system process GO:0003013 183 0.029
cytosolic calcium ion homeostasis GO:0051480 140 0.029
purine containing compound biosynthetic process GO:0072522 85 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
regulation of ion transport GO:0043269 245 0.029
positive regulation of secretion by cell GO:1903532 128 0.029
chemical homeostasis GO:0048878 292 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
nitrogen compound transport GO:0071705 229 0.028
catabolic process GO:0009056 351 0.028
cellular amine metabolic process GO:0044106 38 0.028
purine ribonucleotide biosynthetic process GO:0009152 81 0.027
nucleoside metabolic process GO:0009116 179 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
response to hypoxia GO:0001666 231 0.027
ribonucleoside triphosphate metabolic process GO:0009199 141 0.027
signal release GO:0023061 145 0.027
regulation of transcription dna templated GO:0006355 374 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
negative regulation of gene expression GO:0010629 199 0.026
amine metabolic process GO:0009308 38 0.026
protein complex biogenesis GO:0070271 263 0.026
ribonucleotide catabolic process GO:0009261 136 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
cellular ion homeostasis GO:0006873 184 0.026
cyclic nucleotide biosynthetic process GO:0009190 63 0.026
regulation of system process GO:0044057 208 0.026
proteolysis GO:0006508 175 0.026
response to decreased oxygen levels GO:0036293 237 0.025
regulation of synaptic transmission GO:0050804 141 0.025
cell migration GO:0016477 197 0.025
metal ion transport GO:0030001 289 0.025
purine nucleoside catabolic process GO:0006152 124 0.025
response to oxidative stress GO:0006979 186 0.025
aromatic compound catabolic process GO:0019439 168 0.024
apoptotic process GO:0006915 381 0.024
cation homeostasis GO:0055080 195 0.024
regulation of canonical wnt signaling pathway GO:0060828 4 0.024
regulation of cellular localization GO:0060341 263 0.023
carbohydrate derivative catabolic process GO:1901136 147 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
regulation of secretion by cell GO:1903530 208 0.023
oxoacid metabolic process GO:0043436 290 0.023
defense response GO:0006952 194 0.023
protein complex subunit organization GO:0071822 302 0.023
response to growth factor GO:0070848 189 0.023
cellular cation homeostasis GO:0030003 180 0.023
response to nutrient levels GO:0031667 370 0.023
regulation of nervous system development GO:0051960 264 0.023
regulation of cell development GO:0060284 263 0.022
cellular chemical homeostasis GO:0055082 247 0.022
nucleoside phosphate catabolic process GO:1901292 140 0.022
organophosphate catabolic process GO:0046434 148 0.022
multi organism reproductive process GO:0044703 262 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
regulation of nucleotide catabolic process GO:0030811 65 0.022
regulation of membrane potential GO:0042391 110 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
reproduction GO:0000003 245 0.021
nucleotide biosynthetic process GO:0009165 98 0.021
regulation of hormone levels GO:0010817 187 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
purine nucleoside triphosphate catabolic process GO:0009146 122 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
synaptic growth at neuromuscular junction GO:0051124 1 0.021
regulation of cellular component movement GO:0051270 150 0.021
organelle localization GO:0051640 55 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
regulation of catabolic process GO:0009894 113 0.021
regulation of cell proliferation GO:0042127 359 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.020
response to metal ion GO:0010038 253 0.020
cyclic nucleotide metabolic process GO:0009187 80 0.020
purine nucleotide catabolic process GO:0006195 136 0.020
positive regulation of nucleotide metabolic process GO:0045981 91 0.020
response to hydrogen peroxide GO:0042542 89 0.020
multicellular organism reproduction GO:0032504 233 0.020
sex differentiation GO:0007548 113 0.020
regulation of neurotransmitter levels GO:0001505 42 0.020
programmed cell death GO:0012501 392 0.020
ras protein signal transduction GO:0007265 29 0.019
divalent inorganic cation transport GO:0072511 134 0.019
calcium ion transport GO:0006816 131 0.019
cellular response to stress GO:0033554 269 0.019
ion transmembrane transport GO:0034220 365 0.019
macromolecule localization GO:0033036 252 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
biological adhesion GO:0022610 110 0.019
divalent metal ion transport GO:0070838 132 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
nucleotide catabolic process GO:0009166 139 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
organic acid metabolic process GO:0006082 292 0.019
negative regulation of developmental process GO:0051093 125 0.019
neurotransmitter transport GO:0006836 42 0.019
single organism intracellular transport GO:1902582 166 0.018
positive regulation of secretion GO:0051047 140 0.018
lymphocyte activation involved in immune response GO:0002285 3 0.018
positive regulation of developmental process GO:0051094 283 0.018
locomotion GO:0040011 237 0.018
regulation of calcium ion transport GO:0051924 77 0.018
single organism reproductive process GO:0044702 297 0.017
neurological system process GO:0050877 219 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
vesicle localization GO:0051648 33 0.017
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.017
b cell differentiation GO:0030183 2 0.017
response to monosaccharide GO:0034284 159 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
regulation of transmembrane transport GO:0034762 122 0.017
response to hexose GO:0009746 144 0.017
regulation of catalytic activity GO:0050790 304 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
carboxylic acid metabolic process GO:0019752 289 0.016
cellular lipid metabolic process GO:0044255 208 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
positive regulation of nucleoside metabolic process GO:0045979 55 0.016
developmental process involved in reproduction GO:0003006 159 0.016
regulation of metal ion transport GO:0010959 118 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
negative regulation of cell death GO:0060548 229 0.016
synapse organization GO:0050808 46 0.016
cellular component morphogenesis GO:0032989 155 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
cellular ketone metabolic process GO:0042180 51 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
dendrite development GO:0016358 72 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of gtpase activity GO:0043087 57 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
regulation of cell projection organization GO:0031344 175 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
response to glucose GO:0009749 136 0.015
positive regulation of locomotion GO:0040017 102 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
cytoplasmic transport GO:0016482 115 0.015
calcium ion transport into cytosol GO:0060402 38 0.015
regulation of anatomical structure size GO:0090066 135 0.015
tissue development GO:0009888 252 0.015
heart morphogenesis GO:0003007 3 0.015
regulation of programmed cell death GO:0043067 341 0.015
positive regulation of cell motility GO:2000147 97 0.015
membrane organization GO:0061024 94 0.015
positive regulation of signaling GO:0023056 270 0.015
nucleoside catabolic process GO:0009164 126 0.015
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
hormone transport GO:0009914 121 0.014
gtp metabolic process GO:0046039 72 0.014
establishment of organelle localization GO:0051656 37 0.014
regulation of secretion GO:0051046 224 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
regulation of postsynaptic membrane potential GO:0060078 25 0.014
response to biotic stimulus GO:0009607 226 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
response to organophosphorus GO:0046683 102 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
localization of cell GO:0051674 202 0.014
guanosine containing compound catabolic process GO:1901069 71 0.014
organelle organization GO:0006996 266 0.014
regulation of transmembrane transporter activity GO:0022898 49 0.014
negative regulation of neuron death GO:1901215 69 0.014
protein localization GO:0008104 191 0.014
response to molecule of fungal origin GO:0002238 3 0.014
regulation of stem cell differentiation GO:2000736 2 0.014
organic hydroxy compound biosynthetic process GO:1901617 51 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
aminoglycan biosynthetic process GO:0006023 4 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
response to nutrient GO:0007584 248 0.013
neuron neuron synaptic transmission GO:0007270 60 0.013
regulation of transporter activity GO:0032409 50 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cellular response to lipid GO:0071396 201 0.013
behavior GO:0007610 205 0.013
maintenance of location GO:0051235 17 0.013
phospholipid metabolic process GO:0006644 61 0.013
sequestering of metal ion GO:0051238 9 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
response to peptide hormone GO:0043434 278 0.013
ion homeostasis GO:0050801 212 0.013
sequestering of calcium ion GO:0051208 8 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
intracellular signal transduction GO:0035556 314 0.013
reproductive system development GO:0061458 128 0.013
meiotic cell cycle process GO:1903046 3 0.013
gtp catabolic process GO:0006184 71 0.013
gonad development GO:0008406 104 0.013
potassium ion transport GO:0006813 97 0.013
protein modification by small protein conjugation or removal GO:0070647 35 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
hormone secretion GO:0046879 115 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
neuron projection morphogenesis GO:0048812 122 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of blood circulation GO:1903522 110 0.013
positive regulation of cell development GO:0010720 176 0.013
cell motility GO:0048870 202 0.012
central nervous system development GO:0007417 311 0.012
embryonic pattern specification GO:0009880 1 0.012
positive regulation of nervous system development GO:0051962 178 0.012
glycosaminoglycan biosynthetic process GO:0006024 4 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
negative regulation of neuron apoptotic process GO:0043524 45 0.012
glial cell differentiation GO:0010001 65 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
protein phosphorylation GO:0006468 345 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of protein metabolic process GO:0051246 289 0.012
response to bacterium GO:0009617 200 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
cgmp biosynthetic process GO:0006182 15 0.012
carbohydrate metabolic process GO:0005975 130 0.012
response to external biotic stimulus GO:0043207 221 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.012
positive regulation of ion transport GO:0043270 94 0.012
response to estradiol GO:0032355 164 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of ras protein signal transduction GO:0046578 45 0.011
dendrite morphogenesis GO:0048813 43 0.011
regulation of immune system process GO:0002682 123 0.011
lipid biosynthetic process GO:0008610 128 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
positive regulation of molecular function GO:0044093 230 0.011
regulation of transferase activity GO:0051338 123 0.011
response to other organism GO:0051707 220 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regulation of tube size GO:0035150 89 0.011
response to cytokine GO:0034097 215 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
actin polymerization or depolymerization GO:0008154 14 0.011
positive regulation of gene expression GO:0010628 244 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
regulation of phosphorylation GO:0042325 248 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
immune system process GO:0002376 204 0.011
response to ketone GO:1901654 182 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
growth GO:0040007 165 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
response to peptide GO:1901652 292 0.011
positive regulation of synaptic transmission GO:0050806 62 0.011
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
head development GO:0060322 247 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
protein oligomerization GO:0051259 191 0.010
positive regulation of cell migration GO:0030335 96 0.010
immune response GO:0006955 104 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010
negative regulation of transport GO:0051051 136 0.010
regulation of gtp catabolic process GO:0033124 58 0.010

Arfgap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
nervous system disease DOID:863 0 0.014
muscular disease DOID:0080000 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
myopathy DOID:423 0 0.012
heart disease DOID:114 0 0.012
cardiomyopathy DOID:0050700 0 0.012
dilated cardiomyopathy DOID:12930 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012
cardiovascular system disease DOID:1287 0 0.012
muscle tissue disease DOID:66 0 0.012
muscular dystrophy DOID:9884 0 0.010