Rattus norvegicus

15 known processes

Clca1

chloride channel accessory 1

(Aliases: Clca3)

Clca1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.218
cellular response to oxygen containing compound GO:1901701 386 0.136
positive regulation of cell communication GO:0010647 271 0.133
cellular component movement GO:0006928 248 0.130
positive regulation of multicellular organismal process GO:0051240 387 0.128
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.119
regulation of molecular function GO:0065009 398 0.111
regulation of programmed cell death GO:0043067 341 0.108
regulation of cell differentiation GO:0045595 320 0.105
positive regulation of signaling GO:0023056 270 0.092
response to wounding GO:0009611 254 0.092
cellular response to lipid GO:0071396 201 0.088
organelle organization GO:0006996 266 0.080
localization of cell GO:0051674 202 0.079
negative regulation of metabolic process GO:0009892 331 0.079
regulation of transcription dna templated GO:0006355 374 0.078
response to extracellular stimulus GO:0009991 380 0.077
regulation of multicellular organismal development GO:2000026 376 0.075
cellular response to cytokine stimulus GO:0071345 127 0.073
rna metabolic process GO:0016070 406 0.073
nucleic acid templated transcription GO:0097659 379 0.072
cell migration GO:0016477 197 0.071
transcription from rna polymerase ii promoter GO:0006366 252 0.070
regulation of nucleic acid templated transcription GO:1903506 380 0.070
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.069
response to peptide GO:1901652 292 0.067
positive regulation of protein modification process GO:0031401 142 0.065
regulation of cell proliferation GO:0042127 359 0.065
regulation of neurogenesis GO:0050767 247 0.065
positive regulation of rna biosynthetic process GO:1902680 197 0.062
regulation of system process GO:0044057 208 0.062
transcription dna templated GO:0006351 377 0.062
positive regulation of cellular biosynthetic process GO:0031328 295 0.059
cell projection organization GO:0030030 302 0.058
response to nutrient levels GO:0031667 370 0.058
lipid metabolic process GO:0006629 283 0.058
rna biosynthetic process GO:0032774 380 0.058
negative regulation of cellular metabolic process GO:0031324 281 0.055
cellular response to hormone stimulus GO:0032870 247 0.055
tissue development GO:0009888 252 0.055
regeneration GO:0031099 163 0.054
cell growth GO:0016049 104 0.052
hormone secretion GO:0046879 115 0.050
neuron differentiation GO:0030182 368 0.050
regulation of cellular protein metabolic process GO:0032268 267 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.049
organ regeneration GO:0031100 101 0.049
response to molecule of bacterial origin GO:0002237 194 0.048
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.047
organonitrogen compound biosynthetic process GO:1901566 167 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.046
regulation of rna biosynthetic process GO:2001141 381 0.046
protein phosphorylation GO:0006468 345 0.046
response to peptide hormone GO:0043434 278 0.045
regulation of cell motility GO:2000145 131 0.045
regulation of rna metabolic process GO:0051252 391 0.044
positive regulation of biosynthetic process GO:0009891 319 0.044
regulation of signal transduction GO:0009966 318 0.044
negative regulation of cell death GO:0060548 229 0.044
regulation of neuron differentiation GO:0045664 208 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.043
programmed cell death GO:0012501 392 0.043
neuron development GO:0048666 286 0.042
apoptotic process GO:0006915 381 0.042
negative regulation of signaling GO:0023057 157 0.042
oxoacid metabolic process GO:0043436 290 0.041
positive regulation of phosphate metabolic process GO:0045937 262 0.041
muscle system process GO:0003012 115 0.041
negative regulation of programmed cell death GO:0043069 183 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
cell motility GO:0048870 202 0.040
locomotion GO:0040011 237 0.040
regulation of catalytic activity GO:0050790 304 0.039
negative regulation of biosynthetic process GO:0009890 168 0.039
multi organism reproductive process GO:0044703 262 0.039
cellular response to stress GO:0033554 269 0.039
positive regulation of response to stimulus GO:0048584 285 0.038
positive regulation of cell death GO:0010942 184 0.038
response to oxygen levels GO:0070482 265 0.038
positive regulation of transcription dna templated GO:0045893 197 0.038
regulation of cell growth GO:0001558 85 0.037
positive regulation of signal transduction GO:0009967 175 0.037
negative regulation of cell communication GO:0010648 158 0.037
neuron projection development GO:0031175 273 0.036
regulation of homotypic cell cell adhesion GO:0034110 4 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
chemical homeostasis GO:0048878 292 0.036
positive regulation of cell differentiation GO:0045597 217 0.036
regulation of phosphorylation GO:0042325 248 0.036
regulation of protein phosphorylation GO:0001932 183 0.035
regulation of body fluid levels GO:0050878 90 0.035
cellular lipid metabolic process GO:0044255 208 0.035
head development GO:0060322 247 0.035
positive regulation of developmental process GO:0051094 283 0.034
amine metabolic process GO:0009308 38 0.034
negative regulation of apoptotic process GO:0043066 181 0.034
positive regulation of transport GO:0051050 245 0.034
positive regulation of protein metabolic process GO:0051247 178 0.034
negative regulation of rna metabolic process GO:0051253 123 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
regulation of protein modification process GO:0031399 194 0.033
cellular calcium ion homeostasis GO:0006874 160 0.033
regulation of nervous system development GO:0051960 264 0.033
ribose phosphate metabolic process GO:0019693 235 0.032
negative regulation of developmental process GO:0051093 125 0.032
nucleoside metabolic process GO:0009116 179 0.032
regulation of cell cell adhesion GO:0022407 14 0.032
regulation of neuron projection development GO:0010975 161 0.032
reproductive process GO:0022414 372 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
calcium ion homeostasis GO:0055074 162 0.032
cellular response to organic cyclic compound GO:0071407 202 0.031
negative regulation of rna biosynthetic process GO:1902679 118 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
homeostatic process GO:0042592 331 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
regulation of apoptotic process GO:0042981 335 0.030
carbohydrate metabolic process GO:0005975 130 0.030
negative regulation of gene expression GO:0010629 199 0.030
establishment of anatomical structure orientation GO:0048560 1 0.030
positive regulation of programmed cell death GO:0043068 157 0.029
kidney development GO:0001822 67 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
cellular ion homeostasis GO:0006873 184 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.029
biological adhesion GO:0022610 110 0.029
dna metabolic process GO:0006259 96 0.028
secretion by cell GO:0032940 248 0.028
response to corticosteroid GO:0031960 235 0.028
response to estrogen GO:0043627 232 0.028
positive regulation of protein phosphorylation GO:0001934 135 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
intracellular signal transduction GO:0035556 314 0.028
cell adhesion GO:0007155 110 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
regulation of protein metabolic process GO:0051246 289 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
renal system development GO:0072001 67 0.027
positive regulation of gene expression GO:0010628 244 0.027
organic substance catabolic process GO:1901575 316 0.027
epithelial cell proliferation GO:0050673 54 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
ion transmembrane transport GO:0034220 365 0.026
secretion GO:0046903 307 0.026
organic acid metabolic process GO:0006082 292 0.026
organic anion transport GO:0015711 132 0.026
chromosome segregation GO:0007059 2 0.025
cellular ketone metabolic process GO:0042180 51 0.025
regulation of locomotion GO:0040012 148 0.025
catabolic process GO:0009056 351 0.025
reproduction GO:0000003 245 0.024
response to hypoxia GO:0001666 231 0.024
negative regulation of cell differentiation GO:0045596 99 0.024
regulation of cell development GO:0060284 263 0.024
gland development GO:0048732 155 0.024
positive regulation of molecular function GO:0044093 230 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
immune system process GO:0002376 204 0.024
response to ketone GO:1901654 182 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.024
urogenital system development GO:0001655 78 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
regulation of cell adhesion GO:0030155 52 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
central nervous system development GO:0007417 311 0.023
wound healing GO:0042060 122 0.023
regulation of response to stress GO:0080134 126 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
cellular catabolic process GO:0044248 295 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
single organism catabolic process GO:0044712 283 0.022
positive regulation of hormone secretion GO:0046887 65 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
single organismal cell cell adhesion GO:0016337 42 0.022
single organism carbohydrate catabolic process GO:0044724 40 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
positive regulation of secretion by cell GO:1903532 128 0.022
cellular homeostasis GO:0019725 252 0.021
carbohydrate catabolic process GO:0016052 40 0.021
cell morphogenesis GO:0000902 142 0.021
hormone transport GO:0009914 121 0.021
cellular amine metabolic process GO:0044106 38 0.021
brain development GO:0007420 247 0.021
embryonic appendage morphogenesis GO:0035113 4 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
response to lipopolysaccharide GO:0032496 191 0.021
epithelium development GO:0060429 96 0.021
muscle tissue development GO:0060537 58 0.021
growth GO:0040007 165 0.020
single organism reproductive process GO:0044702 297 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
regulation of transferase activity GO:0051338 123 0.020
cellular chemical homeostasis GO:0055082 247 0.020
embryonic skeletal system development GO:0048706 3 0.020
negative regulation of molecular function GO:0044092 133 0.020
nitrogen compound transport GO:0071705 229 0.020
regulation of hydrolase activity GO:0051336 143 0.020
positive regulation of transferase activity GO:0051347 81 0.020
nucleotide metabolic process GO:0009117 279 0.020
intracellular transport GO:0046907 185 0.020
saliva secretion GO:0046541 3 0.019
regulation of hormone levels GO:0010817 187 0.019
cellular protein localization GO:0034613 122 0.019
positive regulation of nervous system development GO:0051962 178 0.019
positive regulation of cell development GO:0010720 176 0.019
actin mediated cell contraction GO:0070252 12 0.019
embryonic limb morphogenesis GO:0030326 4 0.019
regulation of growth GO:0040008 105 0.019
regulation of catabolic process GO:0009894 113 0.019
negative regulation of transport GO:0051051 136 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.019
response to decreased oxygen levels GO:0036293 237 0.019
amide transport GO:0042886 105 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
behavior GO:0007610 205 0.018
multicellular organism reproduction GO:0032504 233 0.018
macromolecule localization GO:0033036 252 0.018
cellular component morphogenesis GO:0032989 155 0.018
gamete generation GO:0007276 124 0.018
establishment of organ orientation GO:0048561 1 0.018
organophosphate metabolic process GO:0019637 370 0.018
neurological system process GO:0050877 219 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
inflammatory response GO:0006954 150 0.018
ion homeostasis GO:0050801 212 0.018
proteolysis GO:0006508 175 0.018
response to radiation GO:0009314 137 0.018
regulation of secretion by cell GO:1903530 208 0.018
regulation of cell projection organization GO:0031344 175 0.018
heart morphogenesis GO:0003007 3 0.018
cellular carbohydrate metabolic process GO:0044262 72 0.018
blood vessel development GO:0001568 69 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
actin filament based process GO:0030029 86 0.018
response to oxidative stress GO:0006979 186 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
response to bacterium GO:0009617 200 0.017
regulation of hormone secretion GO:0046883 106 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
regulation of cell migration GO:0030334 128 0.017
response to cytokine GO:0034097 215 0.017
embryonic skeletal system morphogenesis GO:0048704 3 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
positive regulation of homotypic cell cell adhesion GO:0034112 2 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
gonad development GO:0008406 104 0.017
response to nutrient GO:0007584 248 0.017
axis specification GO:0009798 4 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
single organism biosynthetic process GO:0044711 342 0.017
muscle structure development GO:0061061 87 0.017
maintenance of location GO:0051235 17 0.017
negative regulation of nervous system development GO:0051961 79 0.017
heterocycle catabolic process GO:0046700 167 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
negative regulation of response to stimulus GO:0048585 155 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.016
response to ionizing radiation GO:0010212 59 0.016
limb morphogenesis GO:0035108 4 0.016
response to glucocorticoid GO:0051384 223 0.016
regulation of kinase activity GO:0043549 117 0.016
regulation of fat cell differentiation GO:0045598 3 0.016
aromatic compound catabolic process GO:0019439 168 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
tube development GO:0035295 89 0.016
jak stat cascade GO:0007259 26 0.016
transmembrane transport GO:0055085 412 0.016
regulation of cellular component movement GO:0051270 150 0.016
regulation of immune system process GO:0002682 123 0.016
response to estradiol GO:0032355 164 0.016
striated muscle tissue development GO:0014706 58 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
signal release GO:0023061 145 0.016
single organism organelle organization GO:1902589 180 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
spermatogenesis GO:0007283 99 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
regulation of lipid metabolic process GO:0019216 68 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
locomotor rhythm GO:0045475 1 0.015
lipid oxidation GO:0034440 30 0.015
positive regulation of kinase activity GO:0033674 77 0.015
generation of precursor metabolites and energy GO:0006091 62 0.015
regulation of organelle organization GO:0033043 80 0.015
response to tumor necrosis factor GO:0034612 56 0.015
lipid storage GO:0019915 1 0.015
cytoskeleton organization GO:0007010 111 0.015
metal ion homeostasis GO:0055065 186 0.015
actin cytoskeleton organization GO:0030036 73 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
rhythmic process GO:0048511 156 0.015
protein localization GO:0008104 191 0.015
purine containing compound metabolic process GO:0072521 253 0.015
regulation of anatomical structure size GO:0090066 135 0.015
regulation of epithelial cell proliferation GO:0050678 49 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
response to mechanical stimulus GO:0009612 134 0.014
response to acid chemical GO:0001101 222 0.014
multicellular organism growth GO:0035264 1 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.014
ras protein signal transduction GO:0007265 29 0.014
alcohol metabolic process GO:0006066 77 0.014
epithelial cell differentiation GO:0030855 71 0.014
cation homeostasis GO:0055080 195 0.014
atp metabolic process GO:0046034 72 0.014
transmission of nerve impulse GO:0019226 42 0.014
vascular process in circulatory system GO:0003018 96 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
response to carbohydrate GO:0009743 183 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
organ morphogenesis GO:0009887 75 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
single organism intracellular transport GO:1902582 166 0.013
retina morphogenesis in camera type eye GO:0060042 1 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
ovulation cycle GO:0042698 67 0.013
regulation of muscle system process GO:0090257 79 0.013
multi multicellular organism process GO:0044706 138 0.013
cellular response to acid chemical GO:0071229 75 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
membrane organization GO:0061024 94 0.013
cell differentiation involved in kidney development GO:0061005 4 0.013
sensory organ development GO:0007423 74 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
cell substrate adhesion GO:0031589 29 0.013
regulation of saliva secretion GO:0046877 3 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.012
male gamete generation GO:0048232 99 0.012
vesicle mediated transport GO:0016192 181 0.012
cellular response to peptide GO:1901653 133 0.012
energy derivation by oxidation of organic compounds GO:0015980 46 0.012
macromolecule catabolic process GO:0009057 58 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.012
mitochondrion organization GO:0007005 35 0.012
cell cell signaling GO:0007267 335 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of membrane potential GO:0042391 110 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
single organism cell adhesion GO:0098602 46 0.012
reproductive structure development GO:0048608 128 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
circadian rhythm GO:0007623 88 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cardiac muscle cell contraction GO:0086003 10 0.012
cytoplasmic transport GO:0016482 115 0.012
response to glucose GO:0009749 136 0.012
cell part morphogenesis GO:0032990 123 0.012
mapk cascade GO:0000165 140 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
regulation of peptide secretion GO:0002791 82 0.012
peptide transport GO:0015833 97 0.012
response to vitamin GO:0033273 131 0.011
lipid localization GO:0010876 62 0.011
appendage morphogenesis GO:0035107 4 0.011
gliogenesis GO:0042063 93 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
metanephric comma shaped body morphogenesis GO:0072278 2 0.011
anion transport GO:0006820 178 0.011
sexual reproduction GO:0019953 148 0.011
regulation of blood circulation GO:1903522 110 0.011
positive regulation of cell migration GO:0030335 96 0.011
response to inorganic substance GO:0010035 377 0.011
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
dephosphorylation GO:0016311 98 0.011
sex differentiation GO:0007548 113 0.011
regulation of response to external stimulus GO:0032101 106 0.011
response to insulin GO:0032868 133 0.011
negative regulation of cell development GO:0010721 82 0.011
gastrulation GO:0007369 2 0.011
regulation of cellular localization GO:0060341 263 0.011
palate development GO:0060021 2 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
positive regulation of peptide hormone secretion GO:0090277 50 0.011
regulation of secretion GO:0051046 224 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
peptide secretion GO:0002790 86 0.011
positive regulation of locomotion GO:0040017 102 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
vasculature development GO:0001944 70 0.011
response to biotic stimulus GO:0009607 226 0.011
regulation of response to wounding GO:1903034 69 0.011
mesonephros development GO:0001823 14 0.011
cellular response to external stimulus GO:0071496 118 0.011
negative regulation of organ growth GO:0046621 3 0.011
regulation of peptide transport GO:0090087 87 0.011
regulation of peptide hormone secretion GO:0090276 80 0.010
negative regulation of growth GO:0045926 37 0.010
cellular response to tumor necrosis factor GO:0071356 46 0.010
carboxylic acid catabolic process GO:0046395 49 0.010
muscle organ development GO:0007517 50 0.010
eye morphogenesis GO:0048592 4 0.010
cellular response to hypoxia GO:0071456 51 0.010
potassium ion transport GO:0006813 97 0.010
positive regulation of peptide secretion GO:0002793 52 0.010
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.010
embryonic pattern specification GO:0009880 1 0.010
oxidation reduction process GO:0055114 304 0.010
positive regulation of saliva secretion GO:0046878 3 0.010
developmental growth GO:0048589 100 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
developmental process involved in reproduction GO:0003006 159 0.010
endocrine process GO:0050886 32 0.010
meiotic cell cycle process GO:1903046 3 0.010

Clca1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
sensory system disease DOID:0050155 0 0.013
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010