Rattus norvegicus

0 known processes

Sesn1

sestrin 1

Sesn1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 38 0.073
cellular response to oxygen containing compound GO:1901701 386 0.073
carboxylic acid metabolic process GO:0019752 289 0.071
organic acid metabolic process GO:0006082 292 0.071
transcription from rna polymerase ii promoter GO:0006366 252 0.066
intracellular signal transduction GO:0035556 314 0.065
Mouse
cellular amino acid metabolic process GO:0006520 107 0.065
rna metabolic process GO:0016070 406 0.064
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.063
apoptotic process GO:0006915 381 0.063
regulation of apoptotic process GO:0042981 335 0.062
nucleic acid templated transcription GO:0097659 379 0.060
cellular ketone metabolic process GO:0042180 51 0.060
regulation of phosphorus metabolic process GO:0051174 349 0.059
programmed cell death GO:0012501 392 0.058
regulation of programmed cell death GO:0043067 341 0.056
negative regulation of cell death GO:0060548 229 0.055
oxoacid metabolic process GO:0043436 290 0.053
regulation of molecular function GO:0065009 398 0.050
regulation of phosphorylation GO:0042325 248 0.050
response to inorganic substance GO:0010035 377 0.049
transcription dna templated GO:0006351 377 0.049
negative regulation of macromolecule metabolic process GO:0010605 260 0.048
regulation of multicellular organismal development GO:2000026 376 0.048
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.047
regulation of cellular amino acid metabolic process GO:0006521 2 0.047
cellular amine metabolic process GO:0044106 38 0.047
regulation of phosphate metabolic process GO:0019220 349 0.045
organophosphate metabolic process GO:0019637 370 0.043
response to nutrient levels GO:0031667 370 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
negative regulation of metabolic process GO:0009892 331 0.042
regulation of rna biosynthetic process GO:2001141 381 0.042
rna biosynthetic process GO:0032774 380 0.042
lipid metabolic process GO:0006629 283 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
protein complex biogenesis GO:0070271 263 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.040
cellular response to stress GO:0033554 269 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
regulation of rna metabolic process GO:0051252 391 0.040
cellular response to organic cyclic compound GO:0071407 202 0.039
protein complex subunit organization GO:0071822 302 0.039
organic substance catabolic process GO:1901575 316 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.038
positive regulation of biosynthetic process GO:0009891 319 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
regulation of protein modification process GO:0031399 194 0.036
response to extracellular stimulus GO:0009991 380 0.036
regulation of cellular component organization GO:0051128 368 0.035
regulation of transcription dna templated GO:0006355 374 0.035
protein phosphorylation GO:0006468 345 0.035
protein complex assembly GO:0006461 263 0.034
negative regulation of apoptotic process GO:0043066 181 0.034
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
regulation of signal transduction GO:0009966 318 0.033
Mouse
regulation of protein metabolic process GO:0051246 289 0.033
regulation of protein phosphorylation GO:0001932 183 0.033
negative regulation of gene expression GO:0010629 199 0.033
cell projection organization GO:0030030 302 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.032
positive regulation of developmental process GO:0051094 283 0.032
cellular response to endogenous stimulus GO:0071495 377 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.030
macromolecular complex assembly GO:0065003 273 0.030
cellular response to lipid GO:0071396 201 0.030
positive regulation of molecular function GO:0044093 230 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
regulation of cell proliferation GO:0042127 359 0.028
cell cycle checkpoint GO:0000075 2 0.028
negative regulation of rna metabolic process GO:0051253 123 0.028
cellular component biogenesis GO:0044085 368 0.028
regulation of catalytic activity GO:0050790 304 0.028
cellular catabolic process GO:0044248 295 0.027
neuron differentiation GO:0030182 368 0.027
single organism biosynthetic process GO:0044711 342 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
brain development GO:0007420 247 0.027
cellular response to nitrogen compound GO:1901699 210 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
response to acid chemical GO:0001101 222 0.026
positive regulation of cellular component organization GO:0051130 200 0.026
neuron projection development GO:0031175 273 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
sulfur compound metabolic process GO:0006790 70 0.025
positive regulation of cell development GO:0010720 176 0.025
cellular component assembly GO:0022607 360 0.025
regulation of nervous system development GO:0051960 264 0.025
negative regulation of rna biosynthetic process GO:1902679 118 0.025
regulation of cell development GO:0060284 263 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
homeostatic process GO:0042592 331 0.024
regulation of cell cycle GO:0051726 73 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
central nervous system development GO:0007417 311 0.023
mitotic cell cycle checkpoint GO:0007093 1 0.023
head development GO:0060322 247 0.023
chemical homeostasis GO:0048878 292 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
protein oligomerization GO:0051259 191 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
regulation of neuron projection development GO:0010975 161 0.022
response to oxidative stress GO:0006979 186 0.022
regulation of cell projection organization GO:0031344 175 0.022
positive regulation of neuron projection development GO:0010976 99 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
catabolic process GO:0009056 351 0.021
regulation of cellular localization GO:0060341 263 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
response to peptide GO:1901652 292 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
response to glucose GO:0009749 136 0.020
multi organism reproductive process GO:0044703 262 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
response to carbohydrate GO:0009743 183 0.019
positive regulation of gene expression GO:0010628 244 0.019
positive regulation of cell death GO:0010942 184 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
regulation of homotypic cell cell adhesion GO:0034110 4 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
regulation of transferase activity GO:0051338 123 0.019
single organism reproductive process GO:0044702 297 0.019
regulation of cell differentiation GO:0045595 320 0.019
negative regulation of cell cycle phase transition GO:1901988 4 0.019
reproductive process GO:0022414 372 0.019
regulation of neuron differentiation GO:0045664 208 0.019
regulation of system process GO:0044057 208 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
purine containing compound metabolic process GO:0072521 253 0.018
cellular response to peptide GO:1901653 133 0.018
regulation of catabolic process GO:0009894 113 0.018
muscle system process GO:0003012 115 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
dna integrity checkpoint GO:0031570 2 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
response to metal ion GO:0010038 253 0.017
response to peptide hormone GO:0043434 278 0.017
cell cycle GO:0007049 101 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
multicellular organism growth GO:0035264 1 0.017
peptidyl amino acid modification GO:0018193 126 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
Mouse
positive regulation of response to stimulus GO:0048584 285 0.017
growth GO:0040007 165 0.017
positive regulation of cell differentiation GO:0045597 217 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
positive regulation of transport GO:0051050 245 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
cellular response to external stimulus GO:0071496 118 0.016
response to hexose GO:0009746 144 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
response to monosaccharide GO:0034284 159 0.016
intracellular transport GO:0046907 185 0.016
cellular chemical homeostasis GO:0055082 247 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
nucleotide metabolic process GO:0009117 279 0.015
ras protein signal transduction GO:0007265 29 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
single organism intracellular transport GO:1902582 166 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
ion transmembrane transport GO:0034220 365 0.015
regulation of kinase activity GO:0043549 117 0.014
nucleotide catabolic process GO:0009166 139 0.014
cell type specific apoptotic process GO:0097285 134 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
response to nutrient GO:0007584 248 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
neuron death GO:0070997 127 0.014
ion homeostasis GO:0050801 212 0.014
cytoplasmic transport GO:0016482 115 0.014
anion transport GO:0006820 178 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cellular homeostasis GO:0019725 252 0.014
organic anion transport GO:0015711 132 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
vesicle mediated transport GO:0016192 181 0.014
neuron development GO:0048666 286 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
immune system process GO:0002376 204 0.014
negative regulation of cell communication GO:0010648 158 0.013
nucleoside metabolic process GO:0009116 179 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
response to glucocorticoid GO:0051384 223 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
regulation of muscle system process GO:0090257 79 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
negative regulation of transport GO:0051051 136 0.013
positive regulation of ion transport GO:0043270 94 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
nitrogen compound transport GO:0071705 229 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
positive regulation of neurogenesis GO:0050769 165 0.012
metal ion transport GO:0030001 289 0.012
negative regulation of developmental process GO:0051093 125 0.012
negative regulation of signaling GO:0023057 157 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
organic acid transport GO:0015849 116 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
response to decreased oxygen levels GO:0036293 237 0.012
heart morphogenesis GO:0003007 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
response to reactive oxygen species GO:0000302 120 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
response to insulin GO:0032868 133 0.012
mapk cascade GO:0000165 140 0.012
dna metabolic process GO:0006259 96 0.012
small molecule biosynthetic process GO:0044283 124 0.012
response to lipopolysaccharide GO:0032496 191 0.012
carboxylic acid transport GO:0046942 115 0.012
multicellular organism reproduction GO:0032504 233 0.012
oxidation reduction process GO:0055114 304 0.012
response to bacterium GO:0009617 200 0.012
regulation of neurogenesis GO:0050767 247 0.012
regulation of hormone levels GO:0010817 187 0.012
response to biotic stimulus GO:0009607 226 0.012
cellular lipid metabolic process GO:0044255 208 0.012
response to corticosteroid GO:0031960 235 0.012
defense response GO:0006952 194 0.012
single organism catabolic process GO:0044712 283 0.011
cellular response to oxidative stress GO:0034599 76 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
response to alkaloid GO:0043279 132 0.011
cellular macromolecule localization GO:0070727 122 0.011
transmembrane transport GO:0055085 412 0.011
biological adhesion GO:0022610 110 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
cofactor metabolic process GO:0051186 95 0.011
positive regulation of protein modification process GO:0031401 142 0.011
reproduction GO:0000003 245 0.011
cell adhesion GO:0007155 110 0.011
response to growth factor GO:0070848 189 0.011
transmission of nerve impulse GO:0019226 42 0.011
heterocycle catabolic process GO:0046700 167 0.011
cation homeostasis GO:0055080 195 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
positive regulation of cell communication GO:0010647 271 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
mitotic dna damage checkpoint GO:0044773 1 0.011
cellular response to acid chemical GO:0071229 75 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
regulation of homeostatic process GO:0032844 101 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of neuron death GO:1901214 115 0.011
neurological system process GO:0050877 219 0.011
spindle organization GO:0007051 2 0.011
cell growth GO:0016049 104 0.010
regulation of membrane potential GO:0042391 110 0.010
regulation of ion transport GO:0043269 245 0.010
protein heterooligomerization GO:0051291 89 0.010
gamete generation GO:0007276 124 0.010
muscle structure development GO:0061061 87 0.010
mitotic spindle organization GO:0007052 2 0.010
positive regulation of transferase activity GO:0051347 81 0.010
regulation of gtpase activity GO:0043087 57 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
cell cell signaling GO:0007267 335 0.010
regulation of protein kinase activity GO:0045859 105 0.010
amide transport GO:0042886 105 0.010

Sesn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.017
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
muscle tissue disease DOID:66 0 0.017
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
cardiovascular system disease DOID:1287 0 0.011