Rattus norvegicus

141 known processes

Pklr

pyruvate kinase, liver and RBC

(Aliases: PK1,Pklg,PKL)

Pklr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.335
carboxylic acid metabolic process GO:0019752 289 0.328
oxoacid metabolic process GO:0043436 290 0.253
positive regulation of multicellular organismal process GO:0051240 387 0.252
cell cell signaling GO:0007267 335 0.224
transmission of nerve impulse GO:0019226 42 0.202
liver development GO:0001889 90 0.180
Rat
response to inorganic substance GO:0010035 377 0.170
neurological system process GO:0050877 219 0.168
cellular response to organic cyclic compound GO:0071407 202 0.167
synaptic transmission GO:0007268 235 0.162
regulation of ion transport GO:0043269 245 0.158
urea metabolic process GO:0019627 5 0.150
vitamin transport GO:0051180 14 0.147
negative regulation of programmed cell death GO:0043069 183 0.141
regeneration GO:0031099 163 0.130
Rat
cellular response to insulin stimulus GO:0032869 81 0.129
transcription dna templated GO:0006351 377 0.129
central nervous system development GO:0007417 311 0.123
cellular response to stress GO:0033554 269 0.122
response to glucose GO:0009749 136 0.120
ion transmembrane transport GO:0034220 365 0.118
rna metabolic process GO:0016070 406 0.112
cellular response to endogenous stimulus GO:0071495 377 0.112
negative regulation of apoptotic process GO:0043066 181 0.105
regulation of nucleic acid templated transcription GO:1903506 380 0.100
rna biosynthetic process GO:0032774 380 0.098
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.093
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.092
cellular response to peptide GO:1901653 133 0.091
response to insulin GO:0032868 133 0.090
protein localization GO:0008104 191 0.089
negative regulation of macromolecule metabolic process GO:0010605 260 0.089
response to starvation GO:0042594 59 0.088
multicellular organismal signaling GO:0035637 44 0.088
single organism behavior GO:0044708 130 0.084
anion transport GO:0006820 178 0.083
cellular amino acid metabolic process GO:0006520 107 0.082
programmed cell death GO:0012501 392 0.082
secretion GO:0046903 307 0.080
transmembrane transport GO:0055085 412 0.080
regulation of molecular function GO:0065009 398 0.078
protein complex subunit organization GO:0071822 302 0.077
skeletal system development GO:0001501 41 0.075
positive regulation of gene expression GO:0010628 244 0.074
cellular response to hormone stimulus GO:0032870 247 0.072
organic acid biosynthetic process GO:0016053 83 0.071
regulation of rna biosynthetic process GO:2001141 381 0.071
apoptotic process GO:0006915 381 0.071
regulation of programmed cell death GO:0043067 341 0.070
alpha amino acid biosynthetic process GO:1901607 23 0.069
cellular response to peptide hormone stimulus GO:0071375 120 0.068
cellular amino acid biosynthetic process GO:0008652 32 0.068
cellular response to nitrogen compound GO:1901699 210 0.068
positive regulation of hydrolase activity GO:0051345 86 0.067
carbohydrate derivative metabolic process GO:1901135 346 0.067
positive regulation of secretion GO:0051047 140 0.067
positive regulation of nucleic acid templated transcription GO:1903508 197 0.067
response to monosaccharide GO:0034284 159 0.067
positive regulation of apoptotic process GO:0043065 154 0.066
cellular response to oxygen containing compound GO:1901701 386 0.065
regulation of apoptotic process GO:0042981 335 0.065
cofactor metabolic process GO:0051186 95 0.065
response to carbohydrate GO:0009743 183 0.064
positive regulation of transcription dna templated GO:0045893 197 0.063
regulation of rna metabolic process GO:0051252 391 0.062
positive regulation of transport GO:0051050 245 0.062
carboxylic acid biosynthetic process GO:0046394 83 0.062
small molecule biosynthetic process GO:0044283 124 0.061
single organism carbohydrate catabolic process GO:0044724 40 0.060
carbohydrate metabolic process GO:0005975 130 0.060
organonitrogen compound biosynthetic process GO:1901566 167 0.059
regulation of transcription dna templated GO:0006355 374 0.058
regulation of cellular localization GO:0060341 263 0.058
organophosphate metabolic process GO:0019637 370 0.058
regulation of secretion by cell GO:1903530 208 0.058
positive regulation of secretion by cell GO:1903532 128 0.058
single organism biosynthetic process GO:0044711 342 0.057
mapk cascade GO:0000165 140 0.055
cellular response to organonitrogen compound GO:0071417 197 0.055
locomotory exploration behavior GO:0035641 1 0.054
regulation of secretion GO:0051046 224 0.054
response to extracellular stimulus GO:0009991 380 0.053
nitrogen compound transport GO:0071705 229 0.053
learning or memory GO:0007611 90 0.052
hormone secretion GO:0046879 115 0.052
nucleic acid templated transcription GO:0097659 379 0.051
cellular component assembly GO:0022607 360 0.050
ribonucleotide metabolic process GO:0009259 231 0.050
purine ribonucleotide catabolic process GO:0009154 136 0.050
coenzyme metabolic process GO:0006732 86 0.049
organic acid transport GO:0015849 116 0.049
cellular ketone metabolic process GO:0042180 51 0.048
regulation of blood pressure GO:0008217 83 0.047
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
response to zinc ion GO:0010043 39 0.047
regulation of multicellular organismal development GO:2000026 376 0.046
nucleotide catabolic process GO:0009166 139 0.045
intracellular signal transduction GO:0035556 314 0.045
acid secretion GO:0046717 48 0.045
regulation of cellular component organization GO:0051128 368 0.045
cellular response to steroid hormone stimulus GO:0071383 93 0.045
positive regulation of synaptic transmission GO:0050806 62 0.045
homeostatic process GO:0042592 331 0.044
nucleoside triphosphate metabolic process GO:0009141 144 0.044
cation transport GO:0006812 382 0.044
response to transition metal nanoparticle GO:1990267 122 0.044
positive regulation of peptide secretion GO:0002793 52 0.043
response to hexose GO:0009746 144 0.043
response to nutrient levels GO:0031667 370 0.043
hepaticobiliary system development GO:0061008 90 0.042
Rat
defense response GO:0006952 194 0.042
inflammatory response GO:0006954 150 0.042
negative regulation of collagen biosynthetic process GO:0032966 4 0.042
organic anion transport GO:0015711 132 0.042
defecation GO:0030421 1 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.041
regulation of cell proliferation GO:0042127 359 0.041
dephosphorylation GO:0016311 98 0.041
single organism carbohydrate metabolic process GO:0044723 118 0.040
regulation of neuron apoptotic process GO:0043523 83 0.040
organophosphate catabolic process GO:0046434 148 0.040
gland development GO:0048732 155 0.040
Rat
response to peptide GO:1901652 292 0.040
organic acid metabolic process GO:0006082 292 0.039
single organism cellular localization GO:1902580 102 0.039
cellular component biogenesis GO:0044085 368 0.039
positive regulation of cell proliferation GO:0008284 249 0.039
response to external biotic stimulus GO:0043207 221 0.039
hexose transport GO:0008645 29 0.039
circulatory system process GO:0003013 183 0.038
macromolecular complex subunit organization GO:0043933 339 0.038
cellular nitrogen compound catabolic process GO:0044270 163 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.037
blood circulation GO:0008015 183 0.037
heterocycle catabolic process GO:0046700 167 0.037
positive regulation of cellular component organization GO:0051130 200 0.037
cytoskeleton organization GO:0007010 111 0.037
response to alkaloid GO:0043279 132 0.036
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.036
amide transport GO:0042886 105 0.036
negative regulation of transcription dna templated GO:0045892 116 0.036
positive regulation of developmental process GO:0051094 283 0.036
negative regulation of metabolic process GO:0009892 331 0.035
regulation of metal ion transport GO:0010959 118 0.035
positive regulation of cellular amine metabolic process GO:0033240 3 0.035
heart morphogenesis GO:0003007 3 0.035
oxidation reduction process GO:0055114 304 0.035
inorganic ion transmembrane transport GO:0098660 229 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
response to estrogen GO:0043627 232 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
regulation of membrane potential GO:0042391 110 0.035
hormone mediated signaling pathway GO:0009755 23 0.035
nicotinamide nucleotide metabolic process GO:0046496 28 0.034
gliogenesis GO:0042063 93 0.034
muscle system process GO:0003012 115 0.034
cytoplasmic transport GO:0016482 115 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.034
regulation of system process GO:0044057 208 0.034
carbohydrate homeostasis GO:0033500 75 0.034
monosaccharide transport GO:0015749 31 0.034
cellular carbohydrate metabolic process GO:0044262 72 0.034
ribose phosphate metabolic process GO:0019693 235 0.033
excretion GO:0007588 24 0.033
brain development GO:0007420 247 0.033
neuronal action potential GO:0019228 35 0.033
purine containing compound metabolic process GO:0072521 253 0.032
negative regulation of cell proliferation GO:0008285 119 0.032
cognition GO:0050890 92 0.032
cellular response to lipid GO:0071396 201 0.032
amine metabolic process GO:0009308 38 0.032
organophosphate biosynthetic process GO:0090407 143 0.032
tissue development GO:0009888 252 0.032
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
amine transport GO:0015837 57 0.031
response to acid chemical GO:0001101 222 0.031
protein homooligomerization GO:0051260 91 0.031
cellular amine metabolic process GO:0044106 38 0.031
nucleoside metabolic process GO:0009116 179 0.030
nucleoside triphosphate catabolic process GO:0009143 123 0.030
positive regulation of cell death GO:0010942 184 0.030
single organism reproductive process GO:0044702 297 0.030
purine nucleotide catabolic process GO:0006195 136 0.030
negative regulation of multicellular organismal process GO:0051241 203 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.030
positive regulation of rna metabolic process GO:0051254 203 0.029
glial cell differentiation GO:0010001 65 0.029
response to glucocorticoid GO:0051384 223 0.029
mesoderm development GO:0007498 2 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.029
neuron apoptotic process GO:0051402 88 0.029
macromolecule localization GO:0033036 252 0.029
anterior posterior pattern specification GO:0009952 1 0.029
chemical homeostasis GO:0048878 292 0.028
purine nucleoside triphosphate metabolic process GO:0009144 141 0.028
regulation of catalytic activity GO:0050790 304 0.028
action potential GO:0001508 54 0.028
catabolic process GO:0009056 351 0.028
muscle contraction GO:0006936 88 0.028
purine ribonucleoside metabolic process GO:0046128 168 0.028
cellular response to glucocorticoid stimulus GO:0071385 68 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
cytokine production GO:0001816 61 0.027
cellular response to extracellular stimulus GO:0031668 73 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
regulation of protein localization GO:0032880 81 0.027
head development GO:0060322 247 0.027
vesicle mediated transport GO:0016192 181 0.027
ion homeostasis GO:0050801 212 0.027
catecholamine secretion GO:0050432 33 0.026
cellular response to external stimulus GO:0071496 118 0.026
secretion by cell GO:0032940 248 0.026
reproductive process GO:0022414 372 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.025
response to decreased oxygen levels GO:0036293 237 0.025
regulation of peptide secretion GO:0002791 82 0.025
nucleoside phosphate catabolic process GO:1901292 140 0.025
actin cytoskeleton organization GO:0030036 73 0.025
purine nucleoside metabolic process GO:0042278 169 0.025
positive regulation of molecular function GO:0044093 230 0.024
regulation of synaptic transmission GO:0050804 141 0.024
glycosyl compound catabolic process GO:1901658 126 0.024
erk1 and erk2 cascade GO:0070371 48 0.024
cellular protein localization GO:0034613 122 0.024
urea cycle GO:0000050 5 0.024
organic substance catabolic process GO:1901575 316 0.024
cellular response to alcohol GO:0097306 87 0.024
positive regulation of cell communication GO:0010647 271 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
regulation of cell differentiation GO:0045595 320 0.024
response to oxygen levels GO:0070482 265 0.023
metal ion transport GO:0030001 289 0.023
negative regulation of gene expression GO:0010629 199 0.023
response to purine containing compound GO:0014074 126 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
regulation of insulin secretion GO:0050796 65 0.023
response to temperature stimulus GO:0009266 94 0.023
monosaccharide metabolic process GO:0005996 61 0.023
Rat
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
positive regulation of homeostatic process GO:0032846 49 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
axis specification GO:0009798 4 0.022
regulation of homeostatic process GO:0032844 101 0.022
organ regeneration GO:0031100 101 0.022
Rat
fructose 2 6 bisphosphate metabolic process GO:0006003 2 0.022
negative regulation of cell communication GO:0010648 158 0.022
regulation of ion transmembrane transport GO:0034765 121 0.022
organelle organization GO:0006996 266 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
response to mineralocorticoid GO:0051385 49 0.022
regulation of cellular response to stress GO:0080135 49 0.021
protein complex biogenesis GO:0070271 263 0.021
regulation of hydrolase activity GO:0051336 143 0.021
regulation of hormone levels GO:0010817 187 0.021
synaptic growth at neuromuscular junction GO:0051124 1 0.021
regulation of growth GO:0040008 105 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
regulation of peptide transport GO:0090087 87 0.021
response to peptide hormone GO:0043434 278 0.021
negative regulation of transport GO:0051051 136 0.021
purine nucleoside triphosphate catabolic process GO:0009146 122 0.021
carboxylic acid transport GO:0046942 115 0.021
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
regulation of cell development GO:0060284 263 0.021
developmental process involved in reproduction GO:0003006 159 0.020
protein oligomerization GO:0051259 191 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
sensory organ development GO:0007423 74 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
response to retinoic acid GO:0032526 63 0.020
positive regulation of signaling GO:0023056 270 0.020
cellular catabolic process GO:0044248 295 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
alpha amino acid metabolic process GO:1901605 71 0.019
regulation of catecholamine secretion GO:0050433 32 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
intracellular transport GO:0046907 185 0.019
regulation of peptide hormone secretion GO:0090276 80 0.019
response to cytokine GO:0034097 215 0.019
forebrain development GO:0030900 98 0.019
single organism catabolic process GO:0044712 283 0.019
actin filament based process GO:0030029 86 0.019
cellular modified amino acid metabolic process GO:0006575 61 0.019
regulation of ion homeostasis GO:2000021 63 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
pyruvate metabolic process GO:0006090 27 0.018
signal release GO:0023061 145 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
macromolecular complex assembly GO:0065003 273 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
glycogen metabolic process GO:0005977 23 0.018
organelle localization GO:0051640 55 0.018
intracellular protein transport GO:0006886 79 0.018
cellular modified amino acid biosynthetic process GO:0042398 18 0.017
energy derivation by oxidation of organic compounds GO:0015980 46 0.017
response to estradiol GO:0032355 164 0.017
cellular macromolecule localization GO:0070727 122 0.017
stress activated mapk cascade GO:0051403 35 0.017
nucleocytoplasmic transport GO:0006913 48 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
cellular response to corticosteroid stimulus GO:0071384 69 0.017
regulation of blood circulation GO:1903522 110 0.017
anion transmembrane transport GO:0098656 77 0.017
response to wounding GO:0009611 254 0.017
Rat
regulation of anatomical structure size GO:0090066 135 0.017
positive regulation of ion transport GO:0043270 94 0.017
aging GO:0007568 241 0.017
protein complex assembly GO:0006461 263 0.017
regulation of phosphorylation GO:0042325 248 0.017
divalent metal ion transport GO:0070838 132 0.016
coenzyme biosynthetic process GO:0009108 22 0.016
nuclear transport GO:0051169 49 0.016
protein transport GO:0015031 132 0.016
response to axon injury GO:0048678 59 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
cellular response to camp GO:0071320 26 0.016
growth GO:0040007 165 0.016
Rat
atp catabolic process GO:0006200 54 0.016
single organism organelle organization GO:1902589 180 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
negative regulation of cell death GO:0060548 229 0.016
ossification GO:0001503 70 0.016
organic hydroxy compound transport GO:0015850 77 0.016
response to hypoxia GO:0001666 231 0.016
cell projection morphogenesis GO:0048858 123 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
peptide secretion GO:0002790 86 0.015
glucan metabolic process GO:0044042 23 0.015
cellular lipid metabolic process GO:0044255 208 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
muscle cell proliferation GO:0033002 84 0.015
positive regulation of cytokine production GO:0001819 42 0.015
behavior GO:0007610 205 0.015
single organism intracellular transport GO:1902582 166 0.015
reproductive structure development GO:0048608 128 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
cellular response to vitamin e GO:0071306 3 0.015
regulation of catabolic process GO:0009894 113 0.015
regulation of neuron projection development GO:0010975 161 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
male sex differentiation GO:0046661 64 0.015
ribonucleoside monophosphate metabolic process GO:0009161 88 0.015
cellular response to oxygen levels GO:0071453 60 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
regulation of carbohydrate metabolic process GO:0006109 41 0.015
memory GO:0007613 54 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
response to cocaine GO:0042220 39 0.015
negative regulation of molecular function GO:0044092 133 0.015
tissue regeneration GO:0042246 36 0.014
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
regulation of organelle organization GO:0033043 80 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
neuron differentiation GO:0030182 368 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
glucose metabolic process GO:0006006 52 0.014
Rat
regulation of nervous system development GO:0051960 264 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
regulation of erk1 and erk2 cascade GO:0070372 41 0.014
glucose homeostasis GO:0042593 75 0.014
axon ensheathment GO:0008366 40 0.014
vesicle localization GO:0051648 33 0.014
regulation of response to external stimulus GO:0032101 106 0.014
regulation of neurogenesis GO:0050767 247 0.014
response to corticosterone GO:0051412 40 0.014
nucleoside monophosphate catabolic process GO:0009125 56 0.014
negative regulation of ion transport GO:0043271 51 0.014
negative regulation of neuron death GO:1901215 69 0.014
cellular polysaccharide metabolic process GO:0044264 23 0.014
serine family amino acid biosynthetic process GO:0009070 4 0.014
connective tissue development GO:0061448 33 0.014
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.014
protein targeting GO:0006605 61 0.014
cellular glucan metabolic process GO:0006073 23 0.014
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
organic cyclic compound catabolic process GO:1901361 175 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
neuron projection development GO:0031175 273 0.013
lipid metabolic process GO:0006629 283 0.013
embryonic pattern specification GO:0009880 1 0.013
response to ketone GO:1901654 182 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.013
cardiac chamber development GO:0003205 1 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
cell cycle checkpoint GO:0000075 2 0.013
endocrine process GO:0050886 32 0.013
spindle organization GO:0007051 2 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.013
urogenital system development GO:0001655 78 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
oxidoreduction coenzyme metabolic process GO:0006733 31 0.013
glucose transport GO:0015758 28 0.013
second messenger mediated signaling GO:0019932 51 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
response to corticosteroid GO:0031960 235 0.013
regulation of neuron death GO:1901214 115 0.013
purine containing compound catabolic process GO:0072523 138 0.013
immune system process GO:0002376 204 0.013
regulation of cell growth GO:0001558 85 0.013
cellular response to hypoxia GO:0071456 51 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.012
cell type specific apoptotic process GO:0097285 134 0.012
inorganic anion transport GO:0015698 41 0.012
wound healing GO:0042060 122 0.012
Rat
cellular response to starvation GO:0009267 27 0.012
positive regulation of phagocytosis engulfment GO:0060100 4 0.012
ensheathment of neurons GO:0007272 40 0.012
exocytosis GO:0006887 60 0.012
oligodendrocyte differentiation GO:0048709 32 0.012
sequestering of metal ion GO:0051238 9 0.012
muscle structure development GO:0061061 87 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
protein import GO:0017038 37 0.012
cellular response to acid chemical GO:0071229 75 0.012
regulation of amine transport GO:0051952 54 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
peptide transport GO:0015833 97 0.012
protein phosphorylation GO:0006468 345 0.012
nucleotide metabolic process GO:0009117 279 0.012
negative regulation of nervous system development GO:0051961 79 0.012
neuron development GO:0048666 286 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
regulation of transcription regulatory region dna binding GO:2000677 4 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
regulation of neuron differentiation GO:0045664 208 0.012
response to fatty acid GO:0070542 65 0.012
response to ethanol GO:0045471 162 0.011
stress activated protein kinase signaling cascade GO:0031098 37 0.011
response to vitamin GO:0033273 131 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of protein metabolic process GO:0051246 289 0.011
antibiotic transport GO:0042891 2 0.011
multicellular organism reproduction GO:0032504 233 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
response to toxic substance GO:0009636 133 0.011
response to platinum ion GO:0070541 4 0.011
visual learning GO:0008542 8 0.011
membrane depolarization GO:0051899 32 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
carbohydrate catabolic process GO:0016052 40 0.011
positive regulation of exocytosis GO:0045921 19 0.011
regulation of hormone secretion GO:0046883 106 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
muscle cell differentiation GO:0042692 52 0.011
regulation of muscle contraction GO:0006937 53 0.011
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.011
regulation of exocytosis GO:0017157 37 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
synapse organization GO:0050808 46 0.011
platelet aggregation GO:0070527 4 0.010
digestive system development GO:0055123 41 0.010
positive regulation of serotonin secretion GO:0014064 1 0.010
embryonic axis specification GO:0000578 1 0.010
extracellular matrix constituent secretion GO:0070278 4 0.010
catecholamine transport GO:0051937 37 0.010
aromatic compound catabolic process GO:0019439 168 0.010
purine nucleoside monophosphate catabolic process GO:0009128 55 0.010
positive regulation of hormone secretion GO:0046887 65 0.010
leukocyte mediated immunity GO:0002443 28 0.010
dicarboxylic acid metabolic process GO:0043648 42 0.010
regulation of tube size GO:0035150 89 0.010
negative regulation of calcium ion import GO:0090281 2 0.010

Pklr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.019
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.013
inherited metabolic disorder DOID:655 0 0.012
connective tissue disease DOID:65 0 0.011