Rattus norvegicus

0 known processes

Nkx3-1

NK3 homeobox 1

(Aliases: MGC124859)

Nkx3-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to hypoxia GO:0001666 231 0.092
Human
positive regulation of multicellular organismal process GO:0051240 387 0.091
Human
regulation of apoptotic process GO:0042981 335 0.082
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.066
Human
tissue development GO:0009888 252 0.063
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.062
Human
rna biosynthetic process GO:0032774 380 0.058
Human
response to inorganic substance GO:0010035 377 0.057
regulation of blood vessel size GO:0050880 89 0.057
programmed cell death GO:0012501 392 0.055
Human
cellular chemical homeostasis GO:0055082 247 0.054
neuron differentiation GO:0030182 368 0.054
response to peptide hormone GO:0043434 278 0.053
cation transport GO:0006812 382 0.050
apoptotic process GO:0006915 381 0.049
Human
macromolecular complex subunit organization GO:0043933 339 0.049
inorganic cation transmembrane transport GO:0098662 202 0.049
response to carbohydrate GO:0009743 183 0.048
response to nutrient levels GO:0031667 370 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
Human
neuron projection development GO:0031175 273 0.045
transmembrane transport GO:0055085 412 0.045
central nervous system development GO:0007417 311 0.042
cell projection organization GO:0030030 302 0.042
regulation of programmed cell death GO:0043067 341 0.041
Human
response to extracellular stimulus GO:0009991 380 0.040
neuron development GO:0048666 286 0.040
homeostatic process GO:0042592 331 0.039
response to ketone GO:1901654 182 0.039
regulation of multicellular organismal development GO:2000026 376 0.038
positive regulation of rna biosynthetic process GO:1902680 197 0.037
Human
response to insulin GO:0032868 133 0.037
cellular response to oxygen containing compound GO:1901701 386 0.037
regulation of ion transport GO:0043269 245 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.037
Human
anatomical structure morphogenesis GO:0009653 298 0.036
positive regulation of gene expression GO:0010628 244 0.035
Human
aging GO:0007568 241 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.034
Human
cellular homeostasis GO:0019725 252 0.034
cellular amino acid metabolic process GO:0006520 107 0.033
epithelium development GO:0060429 96 0.033
g protein coupled receptor signaling pathway GO:0007186 242 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
Human
metal ion transport GO:0030001 289 0.033
chemical homeostasis GO:0048878 292 0.033
cellular ion homeostasis GO:0006873 184 0.031
cellular divalent inorganic cation homeostasis GO:0072503 162 0.031
response to metal ion GO:0010038 253 0.031
neurological system process GO:0050877 219 0.030
response to hexose GO:0009746 144 0.030
nitrogen compound transport GO:0071705 229 0.030
organic acid metabolic process GO:0006082 292 0.029
monovalent inorganic cation transport GO:0015672 172 0.029
neuron projection morphogenesis GO:0048812 122 0.029
negative regulation of metabolic process GO:0009892 331 0.029
Human
brain development GO:0007420 247 0.029
cellular calcium ion homeostasis GO:0006874 160 0.029
synaptic transmission GO:0007268 235 0.028
regulation of cell proliferation GO:0042127 359 0.028
Human
regulation of phosphorus metabolic process GO:0051174 349 0.028
Human
response to monosaccharide GO:0034284 159 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
Human
regulation of body fluid levels GO:0050878 90 0.027
response to decreased oxygen levels GO:0036293 237 0.027
Human
response to nutrient GO:0007584 248 0.026
oxoacid metabolic process GO:0043436 290 0.026
response to peptide GO:1901652 292 0.026
secretion GO:0046903 307 0.026
Human
carboxylic acid metabolic process GO:0019752 289 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
response to external biotic stimulus GO:0043207 221 0.025
gland development GO:0048732 155 0.025
aromatic compound catabolic process GO:0019439 168 0.025
protein oligomerization GO:0051259 191 0.025
ion transmembrane transport GO:0034220 365 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
regulation of transcription dna templated GO:0006355 374 0.025
Human
cation transmembrane transport GO:0098655 263 0.025
regulation of blood circulation GO:1903522 110 0.025
positive regulation of cell differentiation GO:0045597 217 0.024
cellular amine metabolic process GO:0044106 38 0.024
regulation of anatomical structure size GO:0090066 135 0.024
response to acid chemical GO:0001101 222 0.024
vascular process in circulatory system GO:0003018 96 0.024
negative regulation of gene expression GO:0010629 199 0.024
Human
response to toxic substance GO:0009636 133 0.024
cell motility GO:0048870 202 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
Human
positive regulation of transcription dna templated GO:0045893 197 0.023
Human
small gtpase mediated signal transduction GO:0007264 36 0.023
anion transport GO:0006820 178 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
regulation of cell differentiation GO:0045595 320 0.023
cellular response to organic cyclic compound GO:0071407 202 0.022
Human
positive regulation of rna metabolic process GO:0051254 203 0.022
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.022
response to vitamin GO:0033273 131 0.022
response to ethanol GO:0045471 162 0.022
ion homeostasis GO:0050801 212 0.022
response to glucose GO:0009749 136 0.022
proteolysis GO:0006508 175 0.022
Human
head development GO:0060322 247 0.021
protein homooligomerization GO:0051260 91 0.021
transcription dna templated GO:0006351 377 0.021
Human
catabolic process GO:0009056 351 0.021
regulation of cell development GO:0060284 263 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
Human
cellular component movement GO:0006928 248 0.021
positive regulation of developmental process GO:0051094 283 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
anion transmembrane transport GO:0098656 77 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
Human
macromolecular complex assembly GO:0065003 273 0.020
regulation of rna metabolic process GO:0051252 391 0.020
Human
cellular response to abiotic stimulus GO:0071214 85 0.020
single organism reproductive process GO:0044702 297 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
cellular component assembly GO:0022607 360 0.020
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.020
positive regulation of cell death GO:0010942 184 0.020
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.019
Human
response to other organism GO:0051707 220 0.019
rhythmic process GO:0048511 156 0.019
amine metabolic process GO:0009308 38 0.019
protein complex assembly GO:0006461 263 0.019
regulation of cell projection organization GO:0031344 175 0.019
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
Human
negative regulation of multicellular organismal process GO:0051241 203 0.018
heart contraction GO:0060047 57 0.018
cellular component morphogenesis GO:0032989 155 0.018
locomotion GO:0040011 237 0.018
response to ammonium ion GO:0060359 71 0.018
calcium ion homeostasis GO:0055074 162 0.018
urogenital system development GO:0001655 78 0.018
regulation of anion transport GO:0044070 43 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
Human
striated muscle contraction GO:0006941 44 0.018
developmental growth GO:0048589 100 0.018
defense response GO:0006952 194 0.018
regulation of neurogenesis GO:0050767 247 0.017
regulation of nervous system development GO:0051960 264 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
membrane organization GO:0061024 94 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
regulation of signal transduction GO:0009966 318 0.017
Human
purine containing compound metabolic process GO:0072521 253 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
nucleotide metabolic process GO:0009117 279 0.017
action potential GO:0001508 54 0.017
regulation of cellular component organization GO:0051128 368 0.017
intracellular signal transduction GO:0035556 314 0.017
Human
response to estrogen GO:0043627 232 0.017
regulation of phosphate metabolic process GO:0019220 349 0.016
Human
regulation of cellular amine metabolic process GO:0033238 8 0.016
cell migration GO:0016477 197 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
cellular ketone metabolic process GO:0042180 51 0.016
organophosphate metabolic process GO:0019637 370 0.016
multicellular organismal signaling GO:0035637 44 0.016
single organism biosynthetic process GO:0044711 342 0.016
response to cytokine GO:0034097 215 0.016
Human
cellular cation homeostasis GO:0030003 180 0.016
ras protein signal transduction GO:0007265 29 0.016
cation homeostasis GO:0055080 195 0.016
blood circulation GO:0008015 183 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.015
response to corticosteroid GO:0031960 235 0.015
regulation of cellular localization GO:0060341 263 0.015
Human
response to mechanical stimulus GO:0009612 134 0.015
response to estradiol GO:0032355 164 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
nucleic acid templated transcription GO:0097659 379 0.015
Human
purine ribonucleoside metabolic process GO:0046128 168 0.015
response to growth factor GO:0070848 189 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
Human
regulation of catalytic activity GO:0050790 304 0.015
Human
response to glucocorticoid GO:0051384 223 0.015
response to oxygen levels GO:0070482 265 0.015
Human
rna metabolic process GO:0016070 406 0.015
Human
positive regulation of programmed cell death GO:0043068 157 0.015
Human
heterocycle catabolic process GO:0046700 167 0.015
cellular component biogenesis GO:0044085 368 0.014
localization of cell GO:0051674 202 0.014
regulation of protein kinase activity GO:0045859 105 0.014
Human
multi multicellular organism process GO:0044706 138 0.014
cell part morphogenesis GO:0032990 123 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
organic substance catabolic process GO:1901575 316 0.014
nucleoside metabolic process GO:0009116 179 0.014
response to alkaloid GO:0043279 132 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
Human
ribonucleoside catabolic process GO:0042454 126 0.014
cell morphogenesis GO:0000902 142 0.014
growth GO:0040007 165 0.013
sodium ion transmembrane transport GO:0035725 67 0.013
positive regulation of molecular function GO:0044093 230 0.013
Human
protein phosphorylation GO:0006468 345 0.013
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.013
Human
regulation of transmembrane transport GO:0034762 122 0.013
regulation of neuron differentiation GO:0045664 208 0.013
regulation of cellular component movement GO:0051270 150 0.013
response to progesterone GO:0032570 48 0.013
metal ion homeostasis GO:0055065 186 0.013
transmission of nerve impulse GO:0019226 42 0.013
response to wounding GO:0009611 254 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
Human
epithelial cell differentiation GO:0030855 71 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
Human
calcium ion transport GO:0006816 131 0.012
regulation of neuron projection development GO:0010975 161 0.012
cellular response to stress GO:0033554 269 0.012
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
multicellular organism reproduction GO:0032504 233 0.012
gonad development GO:0008406 104 0.012
regulation of protein modification process GO:0031399 194 0.012
Human
circulatory system process GO:0003013 183 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of synaptic transmission GO:0050804 141 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
negative regulation of transport GO:0051051 136 0.012
activation of phospholipase d activity GO:0031584 2 0.012
muscle system process GO:0003012 115 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
phosphatidylinositol dephosphorylation GO:0046856 4 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
reproductive system development GO:0061458 128 0.012
multi organism reproductive process GO:0044703 262 0.012
cell projection morphogenesis GO:0048858 123 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
Human
lipid metabolic process GO:0006629 283 0.012
response to radiation GO:0009314 137 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to electrical stimulus GO:0051602 56 0.012
regulation of membrane potential GO:0042391 110 0.011
regulation of heart contraction GO:0008016 48 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
regulation of metal ion transport GO:0010959 118 0.011
organelle organization GO:0006996 266 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
glucose homeostasis GO:0042593 75 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
protein complex subunit organization GO:0071822 302 0.011
lens fiber cell differentiation GO:0070306 3 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
circadian rhythm GO:0007623 88 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
response to lipopolysaccharide GO:0032496 191 0.011
multicellular organismal water homeostasis GO:0050891 4 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
rho protein signal transduction GO:0007266 11 0.011
liver development GO:0001889 90 0.011
sexual reproduction GO:0019953 148 0.011
cytoplasmic transport GO:0016482 115 0.011
single organism catabolic process GO:0044712 283 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
Human
response to oxidative stress GO:0006979 186 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
reproductive structure development GO:0048608 128 0.011
divalent metal ion transport GO:0070838 132 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
saliva secretion GO:0046541 3 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
organic anion transport GO:0015711 132 0.011
axis specification GO:0009798 4 0.011
negative regulation of cell communication GO:0010648 158 0.011
positive regulation of cell development GO:0010720 176 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
Human
amino acid transport GO:0006865 70 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
Human
response to biotic stimulus GO:0009607 226 0.010
response to activity GO:0014823 73 0.010
cellular response to mechanical stimulus GO:0071260 48 0.010
rna localization GO:0006403 4 0.010
regulation of protein maturation GO:1903317 50 0.010
regulation of neuron death GO:1901214 115 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of protein metabolic process GO:0051246 289 0.010
Human
protein complex biogenesis GO:0070271 263 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
cellular response to external stimulus GO:0071496 118 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
Human
sodium ion transport GO:0006814 82 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010

Nkx3-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
urinary system disease DOID:18 0 0.014
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
sensory system disease DOID:0050155 0 0.011