Rattus norvegicus

25 known processes

Runx2

runt-related transcription factor 2

(Aliases: Cbfa1)

Runx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.067
cellular response to endogenous stimulus GO:0071495 377 0.064
organic acid metabolic process GO:0006082 292 0.062
oxoacid metabolic process GO:0043436 290 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.060
Human
regulation of transcription dna templated GO:0006355 374 0.060
Human
rna biosynthetic process GO:0032774 380 0.055
Human
regulation of cell proliferation GO:0042127 359 0.054
intracellular signal transduction GO:0035556 314 0.054
regulation of multicellular organismal development GO:2000026 376 0.053
Rat
cellular response to oxygen containing compound GO:1901701 386 0.049
cation transport GO:0006812 382 0.048
cell motility GO:0048870 202 0.047
rna metabolic process GO:0016070 406 0.047
Human
apoptotic process GO:0006915 381 0.047
cellular response to hormone stimulus GO:0032870 247 0.047
negative regulation of metabolic process GO:0009892 331 0.047
Human
blood circulation GO:0008015 183 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.045
Human
regulation of cell development GO:0060284 263 0.045
regulation of system process GO:0044057 208 0.045
Rat
programmed cell death GO:0012501 392 0.045
regulation of apoptotic process GO:0042981 335 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.044
Human
muscle cell proliferation GO:0033002 84 0.044
positive regulation of biosynthetic process GO:0009891 319 0.044
Human
response to bacterium GO:0009617 200 0.043
regulation of rna biosynthetic process GO:2001141 381 0.043
Human
behavior GO:0007610 205 0.043
regulation of cell differentiation GO:0045595 320 0.042
response to biotic stimulus GO:0009607 226 0.042
cellular ketone metabolic process GO:0042180 51 0.042
response to extracellular stimulus GO:0009991 380 0.041
cellular catabolic process GO:0044248 295 0.041
response to molecule of bacterial origin GO:0002237 194 0.041
cell projection organization GO:0030030 302 0.041
Fly
regulation of programmed cell death GO:0043067 341 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
Human
organic substance catabolic process GO:1901575 316 0.040
regulation of molecular function GO:0065009 398 0.040
negative regulation of biosynthetic process GO:0009890 168 0.040
Human
cellular response to external stimulus GO:0071496 118 0.039
cellular divalent inorganic cation homeostasis GO:0072503 162 0.039
positive regulation of cell death GO:0010942 184 0.039
cellular calcium ion homeostasis GO:0006874 160 0.038
positive regulation of rna biosynthetic process GO:1902680 197 0.038
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.038
positive regulation of molecular function GO:0044093 230 0.037
localization of cell GO:0051674 202 0.037
cellular metal ion homeostasis GO:0006875 172 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
Human
cellular cation homeostasis GO:0030003 180 0.036
neuron death GO:0070997 127 0.036
protein phosphorylation GO:0006468 345 0.036
negative regulation of transcription dna templated GO:0045892 116 0.035
Human
cation homeostasis GO:0055080 195 0.035
cellular component movement GO:0006928 248 0.035
carbohydrate metabolic process GO:0005975 130 0.035
cell cell signaling GO:0007267 335 0.035
Rat
catabolic process GO:0009056 351 0.035
cellular response to lipid GO:0071396 201 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
regulation of secretion by cell GO:1903530 208 0.035
Rat
positive regulation of rna metabolic process GO:0051254 203 0.035
Human
regulation of phosphate metabolic process GO:0019220 349 0.035
regulation of cellular component organization GO:0051128 368 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
Human
regulation of ion transport GO:0043269 245 0.034
neuron projection development GO:0031175 273 0.034
Fly
calcium ion homeostasis GO:0055074 162 0.034
negative regulation of rna metabolic process GO:0051253 123 0.034
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
metal ion transport GO:0030001 289 0.033
circulatory system process GO:0003013 183 0.033
cellular chemical homeostasis GO:0055082 247 0.033
positive regulation of apoptotic process GO:0043065 154 0.033
response to nutrient levels GO:0031667 370 0.033
metal ion homeostasis GO:0055065 186 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.033
divalent inorganic cation homeostasis GO:0072507 165 0.033
cellular component assembly GO:0022607 360 0.033
negative regulation of cell proliferation GO:0008285 119 0.033
single organism reproductive process GO:0044702 297 0.033
Rat
response to cytokine GO:0034097 215 0.032
single organism carbohydrate metabolic process GO:0044723 118 0.032
cellular ion homeostasis GO:0006873 184 0.032
regulation of catalytic activity GO:0050790 304 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
reproductive process GO:0022414 372 0.032
Rat
neurological system process GO:0050877 219 0.032
regulation of neurogenesis GO:0050767 247 0.032
multi organism reproductive process GO:0044703 262 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
amine metabolic process GO:0009308 38 0.032
positive regulation of programmed cell death GO:0043068 157 0.031
single organism catabolic process GO:0044712 283 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
response to external biotic stimulus GO:0043207 221 0.031
monocarboxylic acid metabolic process GO:0032787 152 0.031
cellular response to cytokine stimulus GO:0071345 127 0.031
cellular amine metabolic process GO:0044106 38 0.031
response to lipopolysaccharide GO:0032496 191 0.031
homeostatic process GO:0042592 331 0.031
nucleic acid templated transcription GO:0097659 379 0.030
Human
cellular homeostasis GO:0019725 252 0.030
locomotion GO:0040011 237 0.030
transcription dna templated GO:0006351 377 0.030
Human
cell migration GO:0016477 197 0.030
chemical homeostasis GO:0048878 292 0.030
regulation of cell projection organization GO:0031344 175 0.030
regulation of protein metabolic process GO:0051246 289 0.030
ion homeostasis GO:0050801 212 0.030
regulation of blood circulation GO:1903522 110 0.030
response to nutrient GO:0007584 248 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.029
Human
muscle system process GO:0003012 115 0.029
neuron differentiation GO:0030182 368 0.029
Fly
lipid metabolic process GO:0006629 283 0.029
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
Human
regulation of neuron death GO:1901214 115 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.028
g protein coupled receptor signaling pathway GO:0007186 242 0.028
brain development GO:0007420 247 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
Human
aging GO:0007568 241 0.027
single organism biosynthetic process GO:0044711 342 0.027
single organism behavior GO:0044708 130 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.027
Human
regulation of cellular protein metabolic process GO:0032268 267 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
negative regulation of molecular function GO:0044092 133 0.027
response to inorganic substance GO:0010035 377 0.027
neuron development GO:0048666 286 0.027
Fly
response to mechanical stimulus GO:0009612 134 0.027
positive regulation of developmental process GO:0051094 283 0.027
Rat
secretion by cell GO:0032940 248 0.027
Rat
organophosphate metabolic process GO:0019637 370 0.027
negative regulation of cell death GO:0060548 229 0.027
regulation of hormone secretion GO:0046883 106 0.027
Rat
negative regulation of gene expression GO:0010629 199 0.027
Human
circulatory system development GO:0072359 134 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
regulation of cell motility GO:2000145 131 0.026
regulation of locomotion GO:0040012 148 0.026
regulation of cell migration GO:0030334 128 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
regulation of smooth muscle cell proliferation GO:0048660 75 0.026
regulation of protein modification process GO:0031399 194 0.026
regulation of metal ion transport GO:0010959 118 0.026
response to ketone GO:1901654 182 0.026
regulation of hormone levels GO:0010817 187 0.025
Rat
tissue development GO:0009888 252 0.025
central nervous system development GO:0007417 311 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
response to oxygen levels GO:0070482 265 0.025
positive regulation of cell differentiation GO:0045597 217 0.024
smooth muscle cell proliferation GO:0048659 77 0.024
response to wounding GO:0009611 254 0.024
response to hypoxia GO:0001666 231 0.024
multicellular organism reproduction GO:0032504 233 0.024
Rat
response to decreased oxygen levels GO:0036293 237 0.024
response to peptide hormone GO:0043434 278 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
Human
regulation of nervous system development GO:0051960 264 0.024
response to acid chemical GO:0001101 222 0.024
cellular response to stress GO:0033554 269 0.023
regulation of cellular component movement GO:0051270 150 0.023
oxidation reduction process GO:0055114 304 0.023
positive regulation of nervous system development GO:0051962 178 0.023
defense response GO:0006952 194 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.023
cellular component biogenesis GO:0044085 368 0.023
regulation of rna metabolic process GO:0051252 391 0.023
Human
regulation of cellular localization GO:0060341 263 0.022
Rat
divalent metal ion transport GO:0070838 132 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
Human
cellular carbohydrate metabolic process GO:0044262 72 0.022
skeletal system development GO:0001501 41 0.022
divalent inorganic cation transport GO:0072511 134 0.022
response to peptide GO:1901652 292 0.022
reproductive system development GO:0061458 128 0.022
Rat
gland development GO:0048732 155 0.022
response to metal ion GO:0010038 253 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
positive regulation of protein modification process GO:0031401 142 0.021
transmembrane transport GO:0055085 412 0.021
regulation of secretion GO:0051046 224 0.021
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
positive regulation of cell development GO:0010720 176 0.021
response to ethanol GO:0045471 162 0.021
response to monosaccharide GO:0034284 159 0.021
multi multicellular organism process GO:0044706 138 0.021
response to purine containing compound GO:0014074 126 0.021
response to estrogen GO:0043627 232 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
inflammatory response GO:0006954 150 0.021
generation of precursor metabolites and energy GO:0006091 62 0.021
positive regulation of locomotion GO:0040017 102 0.021
synaptic transmission GO:0007268 235 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.021
anatomical structure morphogenesis GO:0009653 298 0.020
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
calcium ion transport GO:0006816 131 0.020
negative regulation of developmental process GO:0051093 125 0.020
organ regeneration GO:0031100 101 0.020
regeneration GO:0031099 163 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
Human
nitrogen compound transport GO:0071705 229 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
reproduction GO:0000003 245 0.020
Rat
secretion GO:0046903 307 0.019
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
Human
regulation of catabolic process GO:0009894 113 0.019
protein complex subunit organization GO:0071822 302 0.019
cardiovascular system development GO:0072358 134 0.019
organelle organization GO:0006996 266 0.019
response to insulin GO:0032868 133 0.019
regulation of neuron apoptotic process GO:0043523 83 0.019
positive regulation of gene expression GO:0010628 244 0.019
Human
ribose phosphate metabolic process GO:0019693 235 0.019
response to hexose GO:0009746 144 0.019
response to temperature stimulus GO:0009266 94 0.019
response to glucose GO:0009749 136 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
regulation of smooth muscle cell migration GO:0014910 36 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.018
gliogenesis GO:0042063 93 0.018
muscle cell migration GO:0014812 36 0.018
response to carbohydrate GO:0009743 183 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
regulation of kinase activity GO:0043549 117 0.018
regulation of calcium ion transport GO:0051924 77 0.018
nucleotide metabolic process GO:0009117 279 0.018
response to vitamin GO:0033273 131 0.018
proteolysis GO:0006508 175 0.018
peptidyl amino acid modification GO:0018193 126 0.018
protein complex biogenesis GO:0070271 263 0.018
regulation of transferase activity GO:0051338 123 0.018
fatty acid metabolic process GO:0006631 99 0.018
muscle contraction GO:0006936 88 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.017
hormone transport GO:0009914 121 0.017
Rat
protein complex assembly GO:0006461 263 0.017
ion transmembrane transport GO:0034220 365 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
vascular process in circulatory system GO:0003018 96 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
Human
cell growth GO:0016049 104 0.017
heart process GO:0003015 57 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
heart morphogenesis GO:0003007 3 0.017
lipid biosynthetic process GO:0008610 128 0.017
cell morphogenesis GO:0000902 142 0.016
Fly
muscle structure development GO:0061061 87 0.016
reactive oxygen species metabolic process GO:0072593 37 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
response to other organism GO:0051707 220 0.016
cellular response to alcohol GO:0097306 87 0.016
cognition GO:0050890 92 0.016
heterocycle catabolic process GO:0046700 167 0.016
positive regulation of cell communication GO:0010647 271 0.016
Rat
intestinal absorption GO:0050892 3 0.016
cell type specific apoptotic process GO:0097285 134 0.016
ras protein signal transduction GO:0007265 29 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
development of primary sexual characteristics GO:0045137 107 0.016
Rat
regulation of anatomical structure size GO:0090066 135 0.016
female pregnancy GO:0007565 122 0.016
neuron apoptotic process GO:0051402 88 0.016
positive regulation of secretion GO:0051047 140 0.016
Rat
forebrain development GO:0030900 98 0.016
embryonic appendage morphogenesis GO:0035113 4 0.016
sexual reproduction GO:0019953 148 0.016
small gtpase mediated signal transduction GO:0007264 36 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
anion transport GO:0006820 178 0.015
regulation of homeostatic process GO:0032844 101 0.015
cellular response to lipopolysaccharide GO:0071222 55 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
developmental process involved in reproduction GO:0003006 159 0.015
Rat
response to estradiol GO:0032355 164 0.015
organophosphate catabolic process GO:0046434 148 0.015
purine containing compound metabolic process GO:0072521 253 0.015
regulation of neuron differentiation GO:0045664 208 0.015
regulation of carbohydrate metabolic process GO:0006109 41 0.015
heart contraction GO:0060047 57 0.015
regulation of peptide secretion GO:0002791 82 0.015
striated muscle tissue development GO:0014706 58 0.015
striated muscle contraction GO:0006941 44 0.015
cation transmembrane transport GO:0098655 263 0.015
regulation of phosphorylation GO:0042325 248 0.015
cellular lipid metabolic process GO:0044255 208 0.015
action potential GO:0001508 54 0.015
anterior posterior pattern specification GO:0009952 1 0.015
positive regulation of signaling GO:0023056 270 0.015
Rat
head development GO:0060322 247 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
gastrulation GO:0007369 2 0.015
cell activation GO:0001775 97 0.015
cellular response to organonitrogen compound GO:0071417 197 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
cellular component morphogenesis GO:0032989 155 0.014
Fly
single organism organelle organization GO:1902589 180 0.014
membrane organization GO:0061024 94 0.014
regulation of membrane potential GO:0042391 110 0.014
rhythmic process GO:0048511 156 0.014
Rat
organic cyclic compound catabolic process GO:1901361 175 0.014
reproductive structure development GO:0048608 128 0.014
Rat
cellular response to tumor necrosis factor GO:0071356 46 0.014
appendage morphogenesis GO:0035107 4 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
regulation of blood vessel size GO:0050880 89 0.014
limb morphogenesis GO:0035108 4 0.014
smooth muscle cell migration GO:0014909 36 0.014
positive regulation of smooth muscle cell migration GO:0014911 27 0.014
acute inflammatory response GO:0002526 58 0.014
gonad development GO:0008406 104 0.014
Rat
inorganic ion transmembrane transport GO:0098660 229 0.014
growth GO:0040007 165 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
positive regulation of cell motility GO:2000147 97 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
Rat
regulation of cell growth GO:0001558 85 0.014
eye morphogenesis GO:0048592 4 0.014
positive regulation of transport GO:0051050 245 0.014
Rat
positive regulation of cell migration GO:0030335 96 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
macromolecular complex assembly GO:0065003 273 0.014
single organism carbohydrate catabolic process GO:0044724 40 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
peptide hormone secretion GO:0030072 84 0.014
regulation of tube size GO:0035150 89 0.013
cellular response to acid chemical GO:0071229 75 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
positive regulation of blood circulation GO:1903524 65 0.013
protein oligomerization GO:0051259 191 0.013
alcohol metabolic process GO:0006066 77 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
positive regulation of neuron death GO:1901216 43 0.013
response to corticosteroid GO:0031960 235 0.013
response to radiation GO:0009314 137 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of neuron projection development GO:0010975 161 0.013
glial cell differentiation GO:0010001 65 0.013
response to organophosphorus GO:0046683 102 0.013
regulation of blood pressure GO:0008217 83 0.013
response to oxidative stress GO:0006979 186 0.013
immune response GO:0006955 104 0.013
macromolecule localization GO:0033036 252 0.013
Rat
cholesterol homeostasis GO:0042632 3 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
negative regulation of cell communication GO:0010648 158 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of body fluid levels GO:0050878 90 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
negative regulation of transport GO:0051051 136 0.013
inorganic cation transmembrane transport GO:0098662 202 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.012
nucleoside metabolic process GO:0009116 179 0.012
response to camp GO:0051591 91 0.012
regulation of growth GO:0040008 105 0.012
carbohydrate catabolic process GO:0016052 40 0.012
regulation of muscle system process GO:0090257 79 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
multicellular organism growth GO:0035264 1 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
Rat
transmission of nerve impulse GO:0019226 42 0.012
nucleotide catabolic process GO:0009166 139 0.012
hormone secretion GO:0046879 115 0.012
Rat
hexose metabolic process GO:0019318 58 0.012
intracellular transport GO:0046907 185 0.012
steroid metabolic process GO:0008202 73 0.012
signal release GO:0023061 145 0.012
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
Fly
axis specification GO:0009798 4 0.012
regulation of synaptic transmission GO:0050804 141 0.012
gamete generation GO:0007276 124 0.012
multicellular organismal signaling GO:0035637 44 0.012
embryonic limb morphogenesis GO:0030326 4 0.012
response to tumor necrosis factor GO:0034612 56 0.012
potassium ion transport GO:0006813 97 0.012
dna metabolic process GO:0006259 96 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
amide transport GO:0042886 105 0.012
sex differentiation GO:0007548 113 0.012
Rat
vasculature development GO:0001944 70 0.012
axon development GO:0061564 96 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
vesicle mediated transport GO:0016192 181 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
formation of primary germ layer GO:0001704 1 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
response to retinoic acid GO:0032526 63 0.011
phospholipid metabolic process GO:0006644 61 0.011
peptide secretion GO:0002790 86 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
sensory perception GO:0007600 101 0.011
regulation of phagocytosis engulfment GO:0060099 4 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
negative regulation of innate immune response GO:0045824 4 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
cytoplasmic transport GO:0016482 115 0.011
second messenger mediated signaling GO:0019932 51 0.011
regulation of muscle contraction GO:0006937 53 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
chemosensory behavior GO:0007635 2 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
embryonic skeletal system morphogenesis GO:0048704 3 0.011
chromosome segregation GO:0007059 2 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
response to activity GO:0014823 73 0.011
response to interleukin 1 GO:0070555 55 0.011
learning or memory GO:0007611 90 0.011
sequestering of calcium ion GO:0051208 8 0.011
embryonic skeletal system development GO:0048706 3 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
sequestering of metal ion GO:0051238 9 0.011
organic acid transport GO:0015849 116 0.011
neuronal action potential GO:0019228 35 0.011
regulation of response to stress GO:0080134 126 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
lipid storage GO:0019915 1 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
sterol homeostasis GO:0055092 3 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
Fly
positive regulation of cell projection organization GO:0031346 111 0.011
regulation of epithelial cell proliferation GO:0050678 49 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
embryonic pattern specification GO:0009880 1 0.011
rho protein signal transduction GO:0007266 11 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
organic anion transport GO:0015711 132 0.011
positive regulation of ion transport GO:0043270 94 0.011
negative regulation of signaling GO:0023057 157 0.011
steroid biosynthetic process GO:0006694 48 0.011
establishment of tissue polarity GO:0007164 2 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
nucleoside catabolic process GO:0009164 126 0.011
positive regulation of transferase activity GO:0051347 81 0.010
tube development GO:0035295 89 0.010
dephosphorylation GO:0016311 98 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
purine containing compound catabolic process GO:0072523 138 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
response to alkaloid GO:0043279 132 0.010
positive regulation of phagocytosis engulfment GO:0060100 4 0.010
positive regulation of peptide secretion GO:0002793 52 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of defense response GO:0031347 68 0.010
cell cycle checkpoint GO:0000075 2 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
salivary gland development GO:0007431 3 0.010
blood vessel development GO:0001568 69 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
single organism intracellular transport GO:1902582 166 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
olfactory behavior GO:0042048 2 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010

Runx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
Human
musculoskeletal system disease DOID:17 0 0.042
Human
bone disease DOID:0080001 0 0.022
Human
connective tissue disease DOID:65 0 0.022
Human
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.011
cardiovascular system disease DOID:1287 0 0.011