Rattus norvegicus

0 known processes

Lrrc4b

leucine rich repeat containing 4B

(Aliases: NGL-3,Lrig4)

Lrrc4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.420
inorganic cation transmembrane transport GO:0098662 202 0.397
cardiac muscle cell contraction GO:0086003 10 0.375
cellular component movement GO:0006928 248 0.325
heart contraction GO:0060047 57 0.292
regulation of heart contraction GO:0008016 48 0.277
central nervous system development GO:0007417 311 0.266
heart process GO:0003015 57 0.202
blood circulation GO:0008015 183 0.194
positive regulation of transport GO:0051050 245 0.169
cellular response to endogenous stimulus GO:0071495 377 0.169
regulation of cardiac muscle contraction GO:0055117 17 0.153
muscle contraction GO:0006936 88 0.152
circulatory system process GO:0003013 183 0.148
cellular divalent inorganic cation homeostasis GO:0072503 162 0.140
membrane repolarization GO:0086009 1 0.140
striated muscle contraction GO:0006941 44 0.129
cation transmembrane transport GO:0098655 263 0.128
transmembrane transport GO:0055085 412 0.127
regulation of membrane potential GO:0042391 110 0.126
enzyme linked receptor protein signaling pathway GO:0007167 116 0.123
positive regulation of response to stimulus GO:0048584 285 0.118
muscle system process GO:0003012 115 0.115
metal ion transport GO:0030001 289 0.114
regulation of cellular localization GO:0060341 263 0.114
cell cell signaling GO:0007267 335 0.113
action potential GO:0001508 54 0.112
cardiac muscle contraction GO:0060048 27 0.112
cellular calcium ion homeostasis GO:0006874 160 0.106
positive regulation of multicellular organismal process GO:0051240 387 0.105
cellular ion homeostasis GO:0006873 184 0.103
cytosolic calcium ion homeostasis GO:0051480 140 0.103
actin mediated cell contraction GO:0070252 12 0.097
inflammatory response GO:0006954 150 0.096
cellular metal ion homeostasis GO:0006875 172 0.095
positive regulation of secretion GO:0051047 140 0.091
cellular cation homeostasis GO:0030003 180 0.091
carbohydrate derivative metabolic process GO:1901135 346 0.088
regulation of cellular component movement GO:0051270 150 0.087
cation homeostasis GO:0055080 195 0.086
regulation of membrane repolarization GO:0060306 1 0.086
cellular homeostasis GO:0019725 252 0.081
chemical homeostasis GO:0048878 292 0.079
calcium ion homeostasis GO:0055074 162 0.079
regulation of system process GO:0044057 208 0.076
cellular potassium ion transport GO:0071804 72 0.075
regulation of anatomical structure morphogenesis GO:0022603 141 0.075
brain development GO:0007420 247 0.075
reproductive process GO:0022414 372 0.073
inorganic ion transmembrane transport GO:0098660 229 0.073
secretion by cell GO:0032940 248 0.072
regulation of muscle contraction GO:0006937 53 0.071
locomotion GO:0040011 237 0.069
monovalent inorganic cation transport GO:0015672 172 0.068
cell communication involved in cardiac conduction GO:0086065 2 0.066
neurotrophin production GO:0032898 2 0.066
metal ion homeostasis GO:0055065 186 0.066
circulatory system development GO:0072359 134 0.065
regulation of ion transmembrane transport GO:0034765 121 0.064
single organism reproductive process GO:0044702 297 0.064
neuron projection development GO:0031175 273 0.064
positive regulation of cell proliferation GO:0008284 249 0.063
regulation of nervous system development GO:0051960 264 0.063
regulation of metal ion transport GO:0010959 118 0.061
anatomical structure morphogenesis GO:0009653 298 0.061
cellular response to organic cyclic compound GO:0071407 202 0.060
secretion GO:0046903 307 0.059
protein transport GO:0015031 132 0.058
regulation of secretion by cell GO:1903530 208 0.057
cardiac conduction GO:0061337 2 0.057
apoptotic process GO:0006915 381 0.055
regulation of ion transmembrane transporter activity GO:0032412 48 0.053
response to ethanol GO:0045471 162 0.053
regulation of muscle system process GO:0090257 79 0.052
purine containing compound metabolic process GO:0072521 253 0.051
protein complex assembly GO:0006461 263 0.050
regulation of blood circulation GO:1903522 110 0.049
synaptic transmission GO:0007268 235 0.049
regulation of cell development GO:0060284 263 0.048
divalent inorganic cation homeostasis GO:0072507 165 0.047
ion homeostasis GO:0050801 212 0.046
cellular component biogenesis GO:0044085 368 0.045
cellular chemical homeostasis GO:0055082 247 0.045
gliogenesis GO:0042063 93 0.045
regulation of molecular function GO:0065009 398 0.045
positive regulation of cell migration GO:0030335 96 0.044
neuron development GO:0048666 286 0.044
cellular component assembly GO:0022607 360 0.043
potassium ion transmembrane transport GO:0071805 71 0.043
positive regulation of nervous system development GO:0051962 178 0.042
positive regulation of cell communication GO:0010647 271 0.042
regulation of phosphorylation GO:0042325 248 0.041
homeostatic process GO:0042592 331 0.040
positive regulation of signaling GO:0023056 270 0.038
cardiovascular system development GO:0072358 134 0.036
response to estrogen GO:0043627 232 0.036
defense response GO:0006952 194 0.036
multi organism reproductive process GO:0044703 262 0.036
rna metabolic process GO:0016070 406 0.035
divalent inorganic cation transport GO:0072511 134 0.035
sodium ion transmembrane transport GO:0035725 67 0.034
regulation of striated muscle contraction GO:0006942 21 0.034
response to alkaloid GO:0043279 132 0.033
regulation of ion transport GO:0043269 245 0.033
ventricular cardiac muscle cell action potential GO:0086005 2 0.033
purine ribonucleotide metabolic process GO:0009150 227 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.032
organelle localization GO:0051640 55 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.031
positive regulation of neuron projection development GO:0010976 99 0.031
response to cytokine GO:0034097 215 0.030
immune system process GO:0002376 204 0.030
single organism intracellular transport GO:1902582 166 0.030
response to inorganic substance GO:0010035 377 0.030
regulation of neuron differentiation GO:0045664 208 0.030
cell growth GO:0016049 104 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.029
head development GO:0060322 247 0.029
ribose phosphate biosynthetic process GO:0046390 87 0.029
regulation of synaptic transmission GO:0050804 141 0.029
actin filament based process GO:0030029 86 0.029
sexual reproduction GO:0019953 148 0.029
potassium ion transport GO:0006813 97 0.029
cellular component morphogenesis GO:0032989 155 0.029
intracellular transport GO:0046907 185 0.028
positive regulation of cell development GO:0010720 176 0.028
protein phosphorylation GO:0006468 345 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
regulation of growth GO:0040008 105 0.027
positive regulation of signal transduction GO:0009967 175 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
cell motility GO:0048870 202 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.026
cognition GO:0050890 92 0.026
regulation of neurogenesis GO:0050767 247 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
leptin mediated signaling pathway GO:0033210 3 0.025
neurological system process GO:0050877 219 0.025
protein localization GO:0008104 191 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
ion transmembrane transport GO:0034220 365 0.025
cell migration GO:0016477 197 0.025
cellular response to oxygen containing compound GO:1901701 386 0.024
regulation of transmembrane transport GO:0034762 122 0.024
regulation of cardiac muscle cell contraction GO:0086004 11 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
response to hypoxia GO:0001666 231 0.024
localization of cell GO:0051674 202 0.024
positive regulation of heart contraction GO:0045823 15 0.024
calcium ion transport GO:0006816 131 0.023
response to oxygen levels GO:0070482 265 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
intracellular signal transduction GO:0035556 314 0.023
cellular response to mechanical stimulus GO:0071260 48 0.023
regulation of cell differentiation GO:0045595 320 0.023
positive regulation of developmental process GO:0051094 283 0.023
regulation of secretion GO:0051046 224 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
spermatogenesis GO:0007283 99 0.023
response to estradiol GO:0032355 164 0.023
ribose phosphate metabolic process GO:0019693 235 0.022
regulation of cellular component organization GO:0051128 368 0.022
ribonucleoside monophosphate metabolic process GO:0009161 88 0.022
protein tetramerization GO:0051262 38 0.022
cellular protein localization GO:0034613 122 0.022
regulation of cell proliferation GO:0042127 359 0.022
behavior GO:0007610 205 0.022
multicellular organism reproduction GO:0032504 233 0.022
regulation of neuron projection development GO:0010975 161 0.021
macromolecular complex assembly GO:0065003 273 0.021
divalent metal ion transport GO:0070838 132 0.021
positive regulation of synaptic transmission GO:0050806 62 0.021
response to growth factor GO:0070848 189 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
response to mechanical stimulus GO:0009612 134 0.021
macromolecule localization GO:0033036 252 0.021
signal release GO:0023061 145 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
positive regulation of immune system process GO:0002684 90 0.021
ribonucleotide biosynthetic process GO:0009260 85 0.021
transcription dna templated GO:0006351 377 0.020
regulation of programmed cell death GO:0043067 341 0.020
regulation of transporter activity GO:0032409 50 0.020
aging GO:0007568 241 0.020
second messenger mediated signaling GO:0019932 51 0.020
nucleoside monophosphate metabolic process GO:0009123 93 0.020
melanocyte differentiation GO:0030318 2 0.020
regulation of peptide transport GO:0090087 87 0.020
amine metabolic process GO:0009308 38 0.020
response to ketone GO:1901654 182 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
gamete generation GO:0007276 124 0.020
regulation of catabolic process GO:0009894 113 0.019
vasculature development GO:0001944 70 0.019
calcium ion transport into cytosol GO:0060402 38 0.019
cell projection organization GO:0030030 302 0.019
regulation of transcription dna templated GO:0006355 374 0.019
negative regulation of cell death GO:0060548 229 0.019
positive regulation of blood circulation GO:1903524 65 0.019
blood vessel development GO:0001568 69 0.019
neuron projection morphogenesis GO:0048812 122 0.019
single organism behavior GO:0044708 130 0.019
neuron differentiation GO:0030182 368 0.019
cellular response to organonitrogen compound GO:0071417 197 0.018
secretion by tissue GO:0032941 37 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
regulation of heart rate GO:0002027 16 0.018
sodium ion transport GO:0006814 82 0.018
peptide secretion GO:0002790 86 0.018
positive regulation of ion transport GO:0043270 94 0.018
actin filament based movement GO:0030048 16 0.018
programmed cell death GO:0012501 392 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
negative regulation of metabolic process GO:0009892 331 0.018
nucleotide biosynthetic process GO:0009165 98 0.017
regulation of vesicle mediated transport GO:0060627 81 0.017
regulation of signal transduction GO:0009966 318 0.017
establishment of protein localization GO:0045184 141 0.017
regulation of blood pressure GO:0008217 83 0.017
oxoacid metabolic process GO:0043436 290 0.017
cellular response to drug GO:0035690 30 0.017
protein complex subunit organization GO:0071822 302 0.017
regulation of anatomical structure size GO:0090066 135 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
purine nucleotide biosynthetic process GO:0006164 83 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
positive regulation of calcium ion transport GO:0051928 36 0.017
response to carbohydrate GO:0009743 183 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
neuroepithelial cell differentiation GO:0060563 2 0.017
adult locomotory behavior GO:0008344 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
cellular response to steroid hormone stimulus GO:0071383 93 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
positive regulation of transmembrane transport GO:0034764 25 0.016
male gamete generation GO:0048232 99 0.016
regulation of epithelial cell proliferation GO:0050678 49 0.016
regulation of catalytic activity GO:0050790 304 0.016
maintenance of location GO:0051235 17 0.016
positive regulation of ion transmembrane transport GO:0034767 24 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
sensory perception of pain GO:0019233 73 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
response to glucocorticoid GO:0051384 223 0.015
cell type specific apoptotic process GO:0097285 134 0.015
regulation of locomotion GO:0040012 148 0.015
cardiac muscle cell action potential GO:0086001 5 0.015
neuron projection extension GO:1990138 26 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
regulation of apoptotic process GO:0042981 335 0.015
atp metabolic process GO:0046034 72 0.015
negative regulation of signaling GO:0023057 157 0.015
response to radiation GO:0009314 137 0.015
response to insulin GO:0032868 133 0.015
catabolic process GO:0009056 351 0.015
transmission of nerve impulse GO:0019226 42 0.015
regulation of protein metabolic process GO:0051246 289 0.015
regulation of cell projection organization GO:0031344 175 0.015
calcium ion transmembrane transport GO:0070588 70 0.015
protein complex biogenesis GO:0070271 263 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
regulation of cell growth GO:0001558 85 0.014
cellular amine metabolic process GO:0044106 38 0.014
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.014
membrane depolarization during action potential GO:0086010 1 0.014
regulation of actin filament based movement GO:1903115 12 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
response to purine containing compound GO:0014074 126 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.014
cell cycle GO:0007049 101 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
regulation of transmembrane transporter activity GO:0022898 49 0.013
single organism catabolic process GO:0044712 283 0.013
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.013
renal system development GO:0072001 67 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
reproduction GO:0000003 245 0.013
response to nutrient levels GO:0031667 370 0.013
sequestering of calcium ion GO:0051208 8 0.013
cellular macromolecule localization GO:0070727 122 0.013
response to decreased oxygen levels GO:0036293 237 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
positive regulation of molecular function GO:0044093 230 0.013
immune effector process GO:0002252 53 0.013
sequestering of metal ion GO:0051238 9 0.013
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
response to metal ion GO:0010038 253 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
heart morphogenesis GO:0003007 3 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
organelle organization GO:0006996 266 0.012
regulation of axonogenesis GO:0050770 37 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
neuromuscular process GO:0050905 2 0.012
response to ammonium ion GO:0060359 71 0.012
regulation of homeostatic process GO:0032844 101 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
cell activation GO:0001775 97 0.012
membrane organization GO:0061024 94 0.012
nucleoside metabolic process GO:0009116 179 0.012
vesicle mediated transport GO:0016192 181 0.012
locomotory exploration behavior GO:0035641 1 0.012
response to extracellular stimulus GO:0009991 380 0.012
positive regulation of ion transmembrane transporter activity GO:0032414 13 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of action potential GO:0098900 14 0.012
leukocyte migration GO:0050900 38 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
n methyl d aspartate receptor clustering GO:0097114 2 0.011
anterior posterior pattern specification GO:0009952 1 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
nitrogen compound transport GO:0071705 229 0.011
neurotransmitter gated ion channel clustering GO:0072578 3 0.011
regulation of sensory perception of pain GO:0051930 29 0.011
regulation of neuron death GO:1901214 115 0.011
regulation of defense response GO:0031347 68 0.011
cellular response to external stimulus GO:0071496 118 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
protein oligomerization GO:0051259 191 0.011
single organism membrane organization GO:0044802 74 0.011
negative regulation of cytosolic calcium ion concentration GO:0051481 10 0.011
amide transport GO:0042886 105 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
purine nucleoside monophosphate catabolic process GO:0009128 55 0.011
regulation of protein modification process GO:0031399 194 0.011
calcium mediated signaling GO:0019722 23 0.011
body fluid secretion GO:0007589 41 0.011
lipid storage GO:0019915 1 0.011
glial cell differentiation GO:0010001 65 0.010
response to corticosteroid GO:0031960 235 0.010
positive regulation of leukocyte migration GO:0002687 21 0.010
positive regulation of action potential GO:0045760 8 0.010

Lrrc4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
long qt syndrome DOID:2843 0 0.067
disease of metabolism DOID:0014667 0 0.049
carbohydrate metabolic disorder DOID:2978 0 0.049
inherited metabolic disorder DOID:655 0 0.049
disease of anatomical entity DOID:7 0 0.017
cardiovascular system disease DOID:1287 0 0.017
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013
heart conduction disease DOID:10273 0 0.011