Rattus norvegicus

0 known processes

Alkbh5

alkB, alkylation repair homolog 5 (E. coli)

(Aliases: RGD1309496)

Alkbh5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 316 0.109
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.108
negative regulation of cellular metabolic process GO:0031324 281 0.090
nucleic acid templated transcription GO:0097659 379 0.084
regulation of protein metabolic process GO:0051246 289 0.082
cation transport GO:0006812 382 0.082
regulation of rna biosynthetic process GO:2001141 381 0.075
cellular catabolic process GO:0044248 295 0.073
nucleoside phosphate metabolic process GO:0006753 283 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.070
negative regulation of metabolic process GO:0009892 331 0.068
regulation of rna metabolic process GO:0051252 391 0.067
positive regulation of multicellular organismal process GO:0051240 387 0.063
organelle organization GO:0006996 266 0.062
transcription dna templated GO:0006351 377 0.060
reproductive process GO:0022414 372 0.059
regulation of nucleic acid templated transcription GO:1903506 380 0.058
negative regulation of macromolecule metabolic process GO:0010605 260 0.057
protein oligomerization GO:0051259 191 0.056
rna metabolic process GO:0016070 406 0.054
ubiquitin dependent protein catabolic process GO:0006511 14 0.053
regulation of phosphorus metabolic process GO:0051174 349 0.052
neuron differentiation GO:0030182 368 0.050
regulation of transcription dna templated GO:0006355 374 0.049
macromolecular complex subunit organization GO:0043933 339 0.049
catabolic process GO:0009056 351 0.048
macromolecular complex assembly GO:0065003 273 0.046
transcription from rna polymerase ii promoter GO:0006366 252 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.045
rna biosynthetic process GO:0032774 380 0.044
response to nutrient levels GO:0031667 370 0.042
macromolecule catabolic process GO:0009057 58 0.041
rhythmic process GO:0048511 156 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
cellular component biogenesis GO:0044085 368 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.040
cellular response to stress GO:0033554 269 0.040
positive regulation of rna metabolic process GO:0051254 203 0.040
cell cell signaling GO:0007267 335 0.039
response to inorganic substance GO:0010035 377 0.039
negative regulation of cell death GO:0060548 229 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.037
positive regulation of nervous system development GO:0051962 178 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.037
translation GO:0006412 35 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.036
ribose phosphate metabolic process GO:0019693 235 0.036
protein complex subunit organization GO:0071822 302 0.036
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
cellular homeostasis GO:0019725 252 0.035
negative regulation of gene expression GO:0010629 199 0.035
purine nucleotide metabolic process GO:0006163 229 0.034
proteolysis GO:0006508 175 0.034
response to oxidative stress GO:0006979 186 0.033
response to extracellular stimulus GO:0009991 380 0.033
response to nutrient GO:0007584 248 0.033
purine ribonucleoside metabolic process GO:0046128 168 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
cellular protein localization GO:0034613 122 0.033
regulation of cellular component organization GO:0051128 368 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
cellular component assembly GO:0022607 360 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
protein catabolic process GO:0030163 30 0.031
negative regulation of transcription dna templated GO:0045892 116 0.031
chemical homeostasis GO:0048878 292 0.030
negative regulation of biosynthetic process GO:0009890 168 0.030
anion transport GO:0006820 178 0.030
anatomical structure morphogenesis GO:0009653 298 0.029
multi organism reproductive process GO:0044703 262 0.029
programmed cell death GO:0012501 392 0.029
cellular macromolecule catabolic process GO:0044265 29 0.029
response to metal ion GO:0010038 253 0.028
purine containing compound metabolic process GO:0072521 253 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
neuron development GO:0048666 286 0.027
dna metabolic process GO:0006259 96 0.027
regulation of catabolic process GO:0009894 113 0.027
cell projection organization GO:0030030 302 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
response to oxygen levels GO:0070482 265 0.027
secretion GO:0046903 307 0.027
negative regulation of response to stimulus GO:0048585 155 0.026
heterocycle catabolic process GO:0046700 167 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
intracellular signal transduction GO:0035556 314 0.026
regulation of cell development GO:0060284 263 0.026
single organism catabolic process GO:0044712 283 0.026
cellular response to endogenous stimulus GO:0071495 377 0.025
oxoacid metabolic process GO:0043436 290 0.025
organophosphate metabolic process GO:0019637 370 0.025
regulation of hormone levels GO:0010817 187 0.025
response to hypoxia GO:0001666 231 0.025
circadian rhythm GO:0007623 88 0.024
regulation of cell differentiation GO:0045595 320 0.024
organic acid metabolic process GO:0006082 292 0.024
multicellular organism growth GO:0035264 1 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
regulation of protein modification process GO:0031399 194 0.024
single organism reproductive process GO:0044702 297 0.024
divalent metal ion transport GO:0070838 132 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
single organism intracellular transport GO:1902582 166 0.023
response to growth factor GO:0070848 189 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
cellular component movement GO:0006928 248 0.023
locomotion GO:0040011 237 0.023
response to decreased oxygen levels GO:0036293 237 0.023
head development GO:0060322 247 0.023
apoptotic process GO:0006915 381 0.022
cell motility GO:0048870 202 0.022
cellular ketone metabolic process GO:0042180 51 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
modification dependent macromolecule catabolic process GO:0043632 14 0.022
positive regulation of catabolic process GO:0009896 78 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
positive regulation of developmental process GO:0051094 283 0.022
regulation of cellular localization GO:0060341 263 0.022
response to hydrogen peroxide GO:0042542 89 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
cell migration GO:0016477 197 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
intracellular protein transport GO:0006886 79 0.020
regulation of neuron differentiation GO:0045664 208 0.020
protein phosphorylation GO:0006468 345 0.020
alpha amino acid metabolic process GO:1901605 71 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
positive regulation of signaling GO:0023056 270 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of protein modification process GO:0031401 142 0.019
cell cycle GO:0007049 101 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
single organism biosynthetic process GO:0044711 342 0.019
cellular chemical homeostasis GO:0055082 247 0.019
reproduction GO:0000003 245 0.019
negative regulation of cell communication GO:0010648 158 0.019
protein complex biogenesis GO:0070271 263 0.019
intracellular transport GO:0046907 185 0.019
regulation of phosphorylation GO:0042325 248 0.019
carbohydrate metabolic process GO:0005975 130 0.018
behavior GO:0007610 205 0.018
protein modification by small protein conjugation or removal GO:0070647 35 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
aromatic compound catabolic process GO:0019439 168 0.018
positive regulation of gene expression GO:0010628 244 0.018
nitrogen compound transport GO:0071705 229 0.018
neurological system process GO:0050877 219 0.018
cellular response to nitrogen compound GO:1901699 210 0.017
central nervous system development GO:0007417 311 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
cellular cation homeostasis GO:0030003 180 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
neuron death GO:0070997 127 0.017
regulation of response to external stimulus GO:0032101 106 0.017
aging GO:0007568 241 0.017
gastrulation GO:0007369 2 0.016
circadian regulation of gene expression GO:0032922 3 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
response to reactive oxygen species GO:0000302 120 0.016
growth GO:0040007 165 0.016
axis specification GO:0009798 4 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
alternative mrna splicing via spliceosome GO:0000380 4 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
regulation of membrane potential GO:0042391 110 0.016
response to hexose GO:0009746 144 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.016
positive regulation of cell development GO:0010720 176 0.016
peptide transport GO:0015833 97 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of nervous system development GO:0051960 264 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
cellular macromolecule localization GO:0070727 122 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
response to camp GO:0051591 91 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
regulation of secretion by cell GO:1903530 208 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
homeostatic process GO:0042592 331 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
cellular amine metabolic process GO:0044106 38 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of signal transduction GO:0009966 318 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
sexual reproduction GO:0019953 148 0.015
amine metabolic process GO:0009308 38 0.015
macromolecule localization GO:0033036 252 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
regulation of system process GO:0044057 208 0.015
response to estrogen GO:0043627 232 0.014
spermatogenesis GO:0007283 99 0.014
neuron projection development GO:0031175 273 0.014
response to organophosphorus GO:0046683 102 0.014
nucleoside metabolic process GO:0009116 179 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
calcium ion transport GO:0006816 131 0.014
protein localization GO:0008104 191 0.014
reproductive structure development GO:0048608 128 0.014
hormone transport GO:0009914 121 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
regulation of catalytic activity GO:0050790 304 0.014
regulation of apoptotic process GO:0042981 335 0.014
response to peptide hormone GO:0043434 278 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
negative regulation of signaling GO:0023057 157 0.014
cellular response to external stimulus GO:0071496 118 0.014
regulation of secretion GO:0051046 224 0.014
steroid metabolic process GO:0008202 73 0.014
regulation of locomotion GO:0040012 148 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
response to peptide GO:1901652 292 0.013
developmental process involved in reproduction GO:0003006 159 0.013
muscle system process GO:0003012 115 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
regulation of metal ion transport GO:0010959 118 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of growth GO:0040008 105 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of cellular component movement GO:0051270 150 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of neurogenesis GO:0050767 247 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
multicellular organismal signaling GO:0035637 44 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
lipid biosynthetic process GO:0008610 128 0.013
signal release GO:0023061 145 0.013
response to starvation GO:0042594 59 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
regulation of hormone secretion GO:0046883 106 0.013
muscle contraction GO:0006936 88 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
protein ubiquitination GO:0016567 28 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.012
circulatory system development GO:0072359 134 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
brain development GO:0007420 247 0.012
dephosphorylation GO:0016311 98 0.012
positive regulation of transport GO:0051050 245 0.012
male gamete generation GO:0048232 99 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
metal ion transport GO:0030001 289 0.012
negative regulation of neuron death GO:1901215 69 0.012
regulation of translation GO:0006417 27 0.012
heart morphogenesis GO:0003007 3 0.012
positive regulation of ion transport GO:0043270 94 0.012
regulation of cellular response to stress GO:0080135 49 0.012
embryonic pattern specification GO:0009880 1 0.012
multi multicellular organism process GO:0044706 138 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
single organism cellular localization GO:1902580 102 0.011
transmembrane transport GO:0055085 412 0.011
nuclear import GO:0051170 35 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
regulation of transferase activity GO:0051338 123 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
carbohydrate homeostasis GO:0033500 75 0.011
ncrna processing GO:0034470 3 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
gland development GO:0048732 155 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
localization of cell GO:0051674 202 0.011
positive regulation of homeostatic process GO:0032846 49 0.011
single organism organelle organization GO:1902589 180 0.011
ras protein signal transduction GO:0007265 29 0.011
tube development GO:0035295 89 0.011
sulfur compound metabolic process GO:0006790 70 0.011
oligopeptide transport GO:0006857 4 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
response to glucose GO:0009749 136 0.011
positive regulation of focal adhesion assembly GO:0051894 2 0.011
amide transport GO:0042886 105 0.011
response to carbohydrate GO:0009743 183 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
positive regulation of developmental growth GO:0048639 29 0.011
gonad development GO:0008406 104 0.011
secretion by cell GO:0032940 248 0.011
regulation of neuron projection development GO:0010975 161 0.011
cytoplasmic transport GO:0016482 115 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cation homeostasis GO:0055080 195 0.011
positive regulation of growth GO:0045927 55 0.011
response to ketone GO:1901654 182 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
rho protein signal transduction GO:0007266 11 0.010
divalent inorganic cation transport GO:0072511 134 0.010
single organism behavior GO:0044708 130 0.010
oxidation reduction process GO:0055114 304 0.010
protein heterooligomerization GO:0051291 89 0.010
reproductive system development GO:0061458 128 0.010
cell morphogenesis GO:0000902 142 0.010
response to bacterium GO:0009617 200 0.010
regulation of homeostatic process GO:0032844 101 0.010

Alkbh5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.015
disease of anatomical entity DOID:7 0 0.015
disease of metabolism DOID:0014667 0 0.011
musculoskeletal system disease DOID:17 0 0.011