Rattus norvegicus

13 known processes

Tnni2

troponin I type 2 (skeletal, fast)

Tnni2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.446
tissue development GO:0009888 252 0.412
myosin filament assembly GO:0031034 1 0.316
muscle contraction GO:0006936 88 0.314
single organism catabolic process GO:0044712 283 0.251
skeletal muscle tissue development GO:0007519 31 0.222
striated muscle tissue development GO:0014706 58 0.189
response to wounding GO:0009611 254 0.170
muscle system process GO:0003012 115 0.169
organic substance catabolic process GO:1901575 316 0.163
protein complex biogenesis GO:0070271 263 0.157
oxoacid metabolic process GO:0043436 290 0.148
regulation of behavior GO:0050795 61 0.148
nucleotide catabolic process GO:0009166 139 0.138
glycosyl compound catabolic process GO:1901658 126 0.129
regulation of programmed cell death GO:0043067 341 0.125
striated muscle contraction GO:0006941 44 0.122
cellular response to endogenous stimulus GO:0071495 377 0.117
growth GO:0040007 165 0.113
response to estrogen GO:0043627 232 0.102
apoptotic process GO:0006915 381 0.102
purine ribonucleoside metabolic process GO:0046128 168 0.099
carbohydrate derivative metabolic process GO:1901135 346 0.099
protein complex subunit organization GO:0071822 302 0.099
nucleoside metabolic process GO:0009116 179 0.098
catabolic process GO:0009056 351 0.092
nucleoside catabolic process GO:0009164 126 0.091
regulation of transcription dna templated GO:0006355 374 0.091
ribonucleotide catabolic process GO:0009261 136 0.087
organophosphate metabolic process GO:0019637 370 0.086
protein complex assembly GO:0006461 263 0.085
glycosyl compound metabolic process GO:1901657 182 0.084
muscle organ development GO:0007517 50 0.084
purine containing compound metabolic process GO:0072521 253 0.083
response to peptide hormone GO:0043434 278 0.082
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.081
metal ion transport GO:0030001 289 0.080
muscle tissue development GO:0060537 58 0.078
cellular component biogenesis GO:0044085 368 0.078
ribonucleoside triphosphate catabolic process GO:0009203 122 0.075
negative regulation of cell death GO:0060548 229 0.070
gland development GO:0048732 155 0.070
nucleoside phosphate metabolic process GO:0006753 283 0.069
regulation of sarcomere organization GO:0060297 2 0.068
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.066
aging GO:0007568 241 0.066
cellular response to oxygen containing compound GO:1901701 386 0.065
regeneration GO:0031099 163 0.065
nucleoside triphosphate metabolic process GO:0009141 144 0.064
regulation of apoptotic process GO:0042981 335 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.063
purine ribonucleotide catabolic process GO:0009154 136 0.062
behavior GO:0007610 205 0.061
purine nucleoside triphosphate catabolic process GO:0009146 122 0.060
regulation of system process GO:0044057 208 0.060
cellular ion homeostasis GO:0006873 184 0.059
purine containing compound catabolic process GO:0072523 138 0.059
response to metal ion GO:0010038 253 0.058
response to estradiol GO:0032355 164 0.058
purine nucleoside catabolic process GO:0006152 124 0.058
myosin filament organization GO:0031033 2 0.057
purine ribonucleoside catabolic process GO:0046130 124 0.057
regulation of signal transduction GO:0009966 318 0.057
transmembrane transport GO:0055085 412 0.056
cytoskeleton organization GO:0007010 111 0.055
nucleobase containing small molecule metabolic process GO:0055086 316 0.055
regulation of cellular component organization GO:0051128 368 0.055
wound healing GO:0042060 122 0.055
chemical homeostasis GO:0048878 292 0.054
programmed cell death GO:0012501 392 0.053
ribonucleoside monophosphate metabolic process GO:0009161 88 0.053
feeding behavior GO:0007631 53 0.052
ribonucleoside triphosphate metabolic process GO:0009199 141 0.052
response to inorganic substance GO:0010035 377 0.051
skeletal muscle contraction GO:0003009 17 0.050
cardiac muscle contraction GO:0060048 27 0.050
response to acid chemical GO:0001101 222 0.050
circulatory system process GO:0003013 183 0.049
heterocycle catabolic process GO:0046700 167 0.049
purine nucleoside metabolic process GO:0042278 169 0.049
multi organism reproductive process GO:0044703 262 0.048
twitch skeletal muscle contraction GO:0014721 3 0.048
cellular homeostasis GO:0019725 252 0.047
cation transmembrane transport GO:0098655 263 0.047
muscle structure development GO:0061061 87 0.046
organic cyclic compound catabolic process GO:1901361 175 0.046
negative regulation of metabolic process GO:0009892 331 0.045
regulation of wound healing GO:0061041 14 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
inorganic cation transmembrane transport GO:0098662 202 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.044
nucleobase containing compound catabolic process GO:0034655 152 0.044
atp metabolic process GO:0046034 72 0.043
nucleotide metabolic process GO:0009117 279 0.043
negative regulation of programmed cell death GO:0043069 183 0.043
cellular component assembly GO:0022607 360 0.042
purine ribonucleotide metabolic process GO:0009150 227 0.041
nucleoside phosphate catabolic process GO:1901292 140 0.041
organic acid metabolic process GO:0006082 292 0.041
positive regulation of gene expression GO:0010628 244 0.041
regulation of cell differentiation GO:0045595 320 0.040
regulation of molecular function GO:0065009 398 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
carbohydrate derivative catabolic process GO:1901136 147 0.039
regulation of cell proliferation GO:0042127 359 0.039
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.039
positive regulation of developmental process GO:0051094 283 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
cellular response to stress GO:0033554 269 0.038
reproductive process GO:0022414 372 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
transcription dna templated GO:0006351 377 0.037
rna biosynthetic process GO:0032774 380 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
ribonucleoside metabolic process GO:0009119 174 0.037
epithelium development GO:0060429 96 0.037
nucleic acid templated transcription GO:0097659 379 0.037
organophosphate catabolic process GO:0046434 148 0.037
single organism reproductive process GO:0044702 297 0.036
positive regulation of molecular function GO:0044093 230 0.036
response to corticosteroid GO:0031960 235 0.036
brain development GO:0007420 247 0.036
aromatic compound catabolic process GO:0019439 168 0.036
homeostatic process GO:0042592 331 0.035
multicellular organismal movement GO:0050879 17 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.033
single organism organelle organization GO:1902589 180 0.033
enzyme linked receptor protein signaling pathway GO:0007167 116 0.033
muscle cell differentiation GO:0042692 52 0.033
tissue regeneration GO:0042246 36 0.033
multi multicellular organism process GO:0044706 138 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
organonitrogen compound catabolic process GO:1901565 179 0.032
purine nucleotide metabolic process GO:0006163 229 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
cellular ketone metabolic process GO:0042180 51 0.032
purine nucleoside triphosphate metabolic process GO:0009144 141 0.031
muscle filament sliding GO:0030049 2 0.031
purine nucleotide catabolic process GO:0006195 136 0.031
carbohydrate metabolic process GO:0005975 130 0.031
macromolecular complex assembly GO:0065003 273 0.031
positive regulation of programmed cell death GO:0043068 157 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
ribonucleoside monophosphate catabolic process GO:0009158 55 0.030
response to nutrient levels GO:0031667 370 0.030
response to hexose GO:0009746 144 0.030
response to heat GO:0009408 60 0.029
ribonucleotide metabolic process GO:0009259 231 0.029
diaphragm contraction GO:0002086 2 0.029
cellular nitrogen compound catabolic process GO:0044270 163 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
calcium ion homeostasis GO:0055074 162 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
actin myosin filament sliding GO:0033275 2 0.029
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
organelle organization GO:0006996 266 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.028
ion transmembrane transport GO:0034220 365 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
response to ethanol GO:0045471 162 0.027
response to purine containing compound GO:0014074 126 0.027
muscle organ morphogenesis GO:0048644 1 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
anatomical structure formation involved in morphogenesis GO:0048646 83 0.027
positive regulation of cell death GO:0010942 184 0.026
reproduction GO:0000003 245 0.026
multicellular organismal signaling GO:0035637 44 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
actin filament based process GO:0030029 86 0.026
regulation of rna metabolic process GO:0051252 391 0.025
heart contraction GO:0060047 57 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
cellular catabolic process GO:0044248 295 0.025
locomotion GO:0040011 237 0.025
hepaticobiliary system development GO:0061008 90 0.025
response to transition metal nanoparticle GO:1990267 122 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
multicellular organism reproduction GO:0032504 233 0.025
erythrocyte differentiation GO:0030218 1 0.025
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.024
involuntary skeletal muscle contraction GO:0003011 2 0.024
amine metabolic process GO:0009308 38 0.024
response to peptide GO:1901652 292 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
purine nucleoside monophosphate metabolic process GO:0009126 84 0.024
response to glucocorticoid GO:0051384 223 0.024
blood circulation GO:0008015 183 0.024
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
negative regulation of molecular function GO:0044092 133 0.023
regulation of growth GO:0040008 105 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
heart morphogenesis GO:0003007 3 0.023
central nervous system development GO:0007417 311 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
regulation of developmental growth GO:0048638 45 0.023
divalent inorganic cation transport GO:0072511 134 0.022
negative regulation of cardiac muscle tissue development GO:0055026 3 0.022
neuronal action potential GO:0019228 35 0.022
cellular cation homeostasis GO:0030003 180 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
nucleoside monophosphate catabolic process GO:0009125 56 0.022
neuron differentiation GO:0030182 368 0.022
cellular component movement GO:0006928 248 0.022
positive regulation of cellular component organization GO:0051130 200 0.021
actin crosslink formation GO:0051764 3 0.021
cellular chemical homeostasis GO:0055082 247 0.021
regulation of ion transmembrane transport GO:0034765 121 0.021
carbohydrate catabolic process GO:0016052 40 0.021
musculoskeletal movement GO:0050881 17 0.021
developmental growth GO:0048589 100 0.021
actin filament based movement GO:0030048 16 0.021
regulation of phosphorylation GO:0042325 248 0.021
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.021
cell adhesion GO:0007155 110 0.021
regulation of ion transmembrane transporter activity GO:0032412 48 0.021
liver development GO:0001889 90 0.021
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.021
negative regulation of signaling GO:0023057 157 0.020
cellular glucan metabolic process GO:0006073 23 0.020
head development GO:0060322 247 0.020
mesoderm development GO:0007498 2 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
anterior posterior pattern specification GO:0009952 1 0.020
response to activity GO:0014823 73 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
organ morphogenesis GO:0009887 75 0.019
response to oxidative stress GO:0006979 186 0.019
skeletal muscle tissue regeneration GO:0043403 10 0.019
response to monosaccharide GO:0034284 159 0.019
nucleoside monophosphate metabolic process GO:0009123 93 0.019
glucagon secretion GO:0070091 5 0.019
regulation of organelle organization GO:0033043 80 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
negative regulation of gene expression GO:0010629 199 0.019
response to growth factor GO:0070848 189 0.019
hemostasis GO:0007599 26 0.019
mapk cascade GO:0000165 140 0.019
response to axon injury GO:0048678 59 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.018
cellular amine metabolic process GO:0044106 38 0.018
response to radiation GO:0009314 137 0.018
regulation of cell development GO:0060284 263 0.018
negative regulation of cell proliferation GO:0008285 119 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of purine nucleotide catabolic process GO:0033121 65 0.017
oxidation reduction process GO:0055114 304 0.017
single organism biosynthetic process GO:0044711 342 0.017
negative regulation of cell communication GO:0010648 158 0.017
generation of precursor metabolites and energy GO:0006091 62 0.017
transmission of nerve impulse GO:0019226 42 0.017
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.017
response to carbohydrate GO:0009743 183 0.017
cellular macromolecular complex assembly GO:0034622 58 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
response to electrical stimulus GO:0051602 56 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.017
sexual reproduction GO:0019953 148 0.017
neuron projection development GO:0031175 273 0.016
regulation of homotypic cell cell adhesion GO:0034110 4 0.016
purine nucleoside monophosphate catabolic process GO:0009128 55 0.016
actin cytoskeleton organization GO:0030036 73 0.016
voluntary skeletal muscle contraction GO:0003010 3 0.016
intracellular signal transduction GO:0035556 314 0.016
sequestering of calcium ion GO:0051208 8 0.016
protein oligomerization GO:0051259 191 0.016
response to hypoxia GO:0001666 231 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
cell type specific apoptotic process GO:0097285 134 0.015
regulation of mapk cascade GO:0043408 116 0.015
rna metabolic process GO:0016070 406 0.015
muscle cell proliferation GO:0033002 84 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
secretion by cell GO:0032940 248 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
positive regulation of protein modification process GO:0031401 142 0.015
multicellular organism growth GO:0035264 1 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
regulation of protein metabolic process GO:0051246 289 0.015
neural crest cell differentiation GO:0014033 2 0.015
myofibril assembly GO:0030239 6 0.015
ribonucleoside catabolic process GO:0042454 126 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
purine nucleobase metabolic process GO:0006144 4 0.014
negative regulation of heart growth GO:0061117 3 0.014
nucleotide transmembrane transport GO:1901679 2 0.014
regulation of cell projection organization GO:0031344 175 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
regulation of transmembrane transport GO:0034762 122 0.014
cation transport GO:0006812 382 0.014
metal ion homeostasis GO:0055065 186 0.014
positive regulation of necrotic cell death GO:0010940 4 0.014
coronary vasculature morphogenesis GO:0060977 3 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
erythrocyte aggregation GO:0034117 1 0.014
single organism intracellular transport GO:1902582 166 0.014
regulation of muscle system process GO:0090257 79 0.014
developmental induction GO:0031128 2 0.014
intracellular transport GO:0046907 185 0.014
immune system development GO:0002520 41 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
cation homeostasis GO:0055080 195 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
nucleobase biosynthetic process GO:0046112 2 0.013
gastrulation GO:0007369 2 0.013
lipid biosynthetic process GO:0008610 128 0.013
regulation of catabolic process GO:0009894 113 0.013
rhythmic process GO:0048511 156 0.013
single organism carbohydrate catabolic process GO:0044724 40 0.013
response to temperature stimulus GO:0009266 94 0.013
axis specification GO:0009798 4 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
regulation of nervous system development GO:0051960 264 0.013
atp catabolic process GO:0006200 54 0.013
regulation of ion transport GO:0043269 245 0.013
cell projection organization GO:0030030 302 0.013
heart development GO:0007507 72 0.013
regulation of catalytic activity GO:0050790 304 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
protein transport GO:0015031 132 0.013
response to reactive oxygen species GO:0000302 120 0.013
cellular component assembly involved in morphogenesis GO:0010927 17 0.012
response to glucose GO:0009749 136 0.012
striated muscle cell differentiation GO:0051146 39 0.012
embryonic pattern specification GO:0009880 1 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
defense response GO:0006952 194 0.012
negative regulation of nervous system development GO:0051961 79 0.012
positive regulation of developmental growth GO:0048639 29 0.012
secretion GO:0046903 307 0.012
metanephric part of ureteric bud development GO:0035502 1 0.012
cellular response to peptide GO:1901653 133 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
cellular amino acid biosynthetic process GO:0008652 32 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
neuron development GO:0048666 286 0.012
alcohol metabolic process GO:0006066 77 0.012
response to ketone GO:1901654 182 0.012
negative regulation of signal transduction GO:0009968 83 0.012
cellular protein localization GO:0034613 122 0.012
protein phosphorylation GO:0006468 345 0.011
epithelial cell proliferation GO:0050673 54 0.011
skeletal muscle organ development GO:0060538 33 0.011
protein localization GO:0008104 191 0.011
protein heterooligomerization GO:0051291 89 0.011
regulation of response to external stimulus GO:0032101 106 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
cardiovascular system development GO:0072358 134 0.011
pyruvate metabolic process GO:0006090 27 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
lipid metabolic process GO:0006629 283 0.011
gamete generation GO:0007276 124 0.011
female pregnancy GO:0007565 122 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
renal system development GO:0072001 67 0.011
respiratory system process GO:0003016 3 0.011
regulation of protein modification process GO:0031399 194 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
cell growth GO:0016049 104 0.011
single organism behavior GO:0044708 130 0.011
energy reserve metabolic process GO:0006112 25 0.011
dna metabolic process GO:0006259 96 0.011
ras protein signal transduction GO:0007265 29 0.011
cellular response to lipid GO:0071396 201 0.010
regulation of muscle contraction GO:0006937 53 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
synaptic transmission GO:0007268 235 0.010
positive regulation of transport GO:0051050 245 0.010
positive regulation of homotypic cell cell adhesion GO:0034112 2 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
negative regulation of cell development GO:0010721 82 0.010
actin mediated cell contraction GO:0070252 12 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
cellular protein complex assembly GO:0043623 44 0.010
response to extracellular stimulus GO:0009991 380 0.010
vesicle mediated transport GO:0016192 181 0.010
respiratory gaseous exchange GO:0007585 4 0.010
sequestering of metal ion GO:0051238 9 0.010

Tnni2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.105
musculoskeletal system disease DOID:17 0 0.105
muscular disease DOID:0080000 0 0.035
retinal disease DOID:5679 0 0.027
night blindness DOID:8499 0 0.027
sensory system disease DOID:0050155 0 0.027
eye and adnexa disease DOID:1492 0 0.027
nervous system disease DOID:863 0 0.027
eye disease DOID:5614 0 0.027
muscle tissue disease DOID:66 0 0.023
myopathy DOID:423 0 0.020
disease of metabolism DOID:0014667 0 0.012