|
|
protein refolding
|
GO:0042026 |
3 |
1.000
|
Yeast |
|
|
chaperone mediated protein folding
|
GO:0061077 |
6 |
0.999
|
|
|
|
response to heat
|
GO:0009408 |
60 |
0.987
|
|
|
|
de novo posttranslational protein folding
|
GO:0051084 |
2 |
0.956
|
|
|
|
de novo protein folding
|
GO:0006458 |
2 |
0.943
|
Yeast |
|
|
chaperone mediated protein folding requiring cofactor
|
GO:0051085 |
2 |
0.914
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
9 |
0.869
|
Rat |
|
|
protein transport
|
GO:0015031 |
132 |
0.868
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.802
|
Rat |
|
|
protein folding
|
GO:0006457 |
12 |
0.793
|
Yeast |
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.676
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.633
|
Yeast Zebrafish |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
44 |
0.626
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.608
|
Mouse Rat |
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.581
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
20 |
0.564
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.552
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.551
|
Rat |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.534
|
Rat |
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.534
|
|
|
|
response to unfolded protein
|
GO:0006986 |
6 |
0.524
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.516
|
Rat |
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.512
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
84 |
0.499
|
Yeast |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
17 |
0.468
|
|
|
|
atp metabolic process
|
GO:0046034 |
72 |
0.462
|
Yeast |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.444
|
|
|
|
positive regulation of protein import into nucleus translocation
|
GO:0033160 |
7 |
0.441
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.440
|
Rat |
|
|
positive regulation of cardiac muscle contraction
|
GO:0060452 |
4 |
0.435
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.435
|
Rat |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
45 |
0.433
|
Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.431
|
Rat |
|
|
cell motility
|
GO:0048870 |
202 |
0.427
|
|
|
|
toxin transport
|
GO:1901998 |
3 |
0.425
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.423
|
Rat |
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
7 |
0.414
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
1 |
0.396
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
8 |
0.395
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.387
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.385
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.382
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
94 |
0.375
|
|
|
|
protein transmembrane transport
|
GO:0071806 |
2 |
0.367
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
1 |
0.363
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
13 |
0.356
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
17 |
0.356
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.350
|
Rat |
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.348
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.347
|
Rat |
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.341
|
Yeast |
|
|
response to topologically incorrect protein
|
GO:0035966 |
8 |
0.339
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
56 |
0.320
|
Yeast |
|
|
regulation of response to tumor cell
|
GO:0002834 |
3 |
0.319
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.317
|
Mouse Rat |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.303
|
Yeast |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.295
|
Yeast |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.293
|
Yeast |
|
|
response to estrogen
|
GO:0043627 |
232 |
0.289
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.284
|
Rat |
|
|
regulation of jnk cascade
|
GO:0046328 |
19 |
0.283
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.282
|
Rat |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
84 |
0.282
|
Yeast |
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.279
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.268
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.267
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.259
|
Yeast Mouse |
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.259
|
Rat |
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.253
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.250
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.250
|
Yeast |
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.249
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
19 |
0.245
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
55 |
0.245
|
Yeast |
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.239
|
Rat |
|
|
cellular protein catabolic process
|
GO:0044257 |
19 |
0.239
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.232
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.232
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
1 |
0.227
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.222
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.214
|
Rat |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.208
|
Rat |
|
|
circulatory system process
|
GO:0003013 |
183 |
0.202
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.202
|
|
|
|
response to atp
|
GO:0033198 |
13 |
0.198
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.195
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.195
|
Rat |
|
|
mapk cascade
|
GO:0000165 |
140 |
0.195
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.191
|
Rat |
|
|
secretion
|
GO:0046903 |
307 |
0.189
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.186
|
Yeast |
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.186
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.180
|
Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.178
|
Rat |
|
|
catabolic process
|
GO:0009056 |
351 |
0.175
|
Yeast |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
16 |
0.169
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
55 |
0.166
|
Yeast |
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.160
|
Rat |
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.160
|
Yeast |
|
|
protein targeting
|
GO:0006605 |
61 |
0.157
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.157
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
29 |
0.157
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.156
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.155
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
2 |
0.150
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.148
|
Rat |
|
|
apoptotic process
|
GO:0006915 |
381 |
0.145
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.145
|
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
1 |
0.143
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
9 |
0.137
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.136
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.130
|
|
|
|
detection of stimulus
|
GO:0051606 |
24 |
0.129
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.129
|
Yeast Zebrafish |
|
|
cerebellar purkinje cell layer development
|
GO:0021680 |
2 |
0.129
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.125
|
Yeast |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.120
|
Rat |
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.117
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.117
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.114
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.114
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
23 |
0.111
|
|
|
|
mitochondrion organization
|
GO:0007005 |
35 |
0.110
|
Yeast |
|
|
immune effector process
|
GO:0002252 |
53 |
0.108
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.108
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.108
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.107
|
Yeast |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.107
|
Yeast |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.107
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.106
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.106
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.106
|
Rat |
|
|
protein localization
|
GO:0008104 |
191 |
0.105
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
37 |
0.104
|
|
|
|
mitochondrial transport
|
GO:0006839 |
19 |
0.103
|
Yeast |
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.103
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.102
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
60 |
0.102
|
Yeast |
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.101
|
Rat |
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.101
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.101
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.100
|
Rat |
|
|
jnk cascade
|
GO:0007254 |
28 |
0.099
|
|
|
|
isotype switching
|
GO:0045190 |
1 |
0.098
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.097
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.097
|
Yeast |
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.097
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.097
|
Yeast |
|
|
response to peptide
|
GO:1901652 |
292 |
0.094
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.094
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.094
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
10 |
0.093
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.093
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.093
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.093
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.091
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.091
|
Yeast |
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.088
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.087
|
Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.087
|
Rat |
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.086
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.086
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.086
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.086
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.085
|
Rat |
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.085
|
Yeast Zebrafish |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.085
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.085
|
Rat |
|
|
dna replication
|
GO:0006260 |
37 |
0.085
|
Yeast |
|
|
positive regulation of protein transport
|
GO:0051222 |
41 |
0.084
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
3 |
0.084
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.084
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.083
|
Yeast |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.083
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.081
|
Yeast Zebrafish |
|
|
proteolysis
|
GO:0006508 |
175 |
0.081
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
83 |
0.080
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.080
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
2 |
0.079
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.078
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
28 |
0.077
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.077
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.076
|
Yeast |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.076
|
Rat |
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.075
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.075
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.075
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.074
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
8 |
0.074
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.073
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
10 |
0.073
|
Yeast |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
13 |
0.072
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
23 |
0.071
|
|
|
|
blood vessel development
|
GO:0001568 |
69 |
0.071
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.071
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
4 |
0.070
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.070
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
3 |
0.069
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.069
|
Yeast Zebrafish |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.069
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.069
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
118 |
0.069
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.069
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.068
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.068
|
Yeast |
|
|
cell migration
|
GO:0016477 |
197 |
0.068
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.068
|
Yeast |
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.068
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.068
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.067
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.067
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.067
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.066
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.065
|
Yeast |
|
|
regulation of cell activation
|
GO:0050865 |
50 |
0.064
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
10 |
0.064
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.063
|
Yeast |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.063
|
Yeast |
|
|
protein localization to mitochondrion
|
GO:0070585 |
7 |
0.062
|
Yeast |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.062
|
Yeast |
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.062
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.061
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.061
|
|
|
|
protein catabolic process
|
GO:0030163 |
30 |
0.061
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.060
|
Rat |
|
|
neuron projection development
|
GO:0031175 |
273 |
0.060
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.059
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.059
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.059
|
Yeast |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.059
|
Yeast |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.059
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.058
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.058
|
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
38 |
0.058
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.058
|
|
|
|
growth
|
GO:0040007 |
165 |
0.057
|
|
|
|
angiogenesis
|
GO:0001525 |
53 |
0.057
|
|
|
|
oxidation reduction process
|
GO:0055114 |
304 |
0.057
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
23 |
0.057
|
|
|
|
cellular response to heat
|
GO:0034605 |
9 |
0.057
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.056
|
Yeast |
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.056
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.056
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.056
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.055
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.055
|
|
|
|
axonogenesis
|
GO:0007409 |
71 |
0.054
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
19 |
0.054
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
44 |
0.054
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
4 |
0.053
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.052
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.052
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.052
|
Yeast |
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.052
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
69 |
0.052
|
Rat |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.052
|
|
|
|
response to tumor cell
|
GO:0002347 |
4 |
0.051
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.051
|
|
|
|
protein import into nucleus
|
GO:0006606 |
35 |
0.050
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
5 |
0.050
|
|
|
|
centrosome organization
|
GO:0051297 |
1 |
0.050
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.048
|
|
|
|
protein localization to membrane
|
GO:0072657 |
36 |
0.048
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.048
|
Rat |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
37 |
0.048
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
36 |
0.047
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.047
|
Yeast |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.047
|
Yeast |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
55 |
0.046
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.046
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.046
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.046
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
1 |
0.046
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
28 |
0.046
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.045
|
Yeast |
|
|
protein import
|
GO:0017038 |
37 |
0.045
|
|
|
|
axonal fasciculation
|
GO:0007413 |
5 |
0.045
|
|
|
|
cellular response to xenobiotic stimulus
|
GO:0071466 |
19 |
0.045
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.045
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
24 |
0.044
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.044
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.044
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
7 |
0.044
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.044
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.043
|
|
|
|
positive regulation of monooxygenase activity
|
GO:0032770 |
5 |
0.043
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.043
|
|
|
|
positive regulation of lamellipodium organization
|
GO:1902745 |
4 |
0.042
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.042
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.042
|
Yeast Zebrafish |
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
8 |
0.042
|
Yeast |
|
|
kidney development
|
GO:0001822 |
67 |
0.042
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.042
|
Zebrafish |
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
1 |
0.041
|
|
|
|
regulation of immune response
|
GO:0050776 |
55 |
0.041
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
4 |
0.041
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.041
|
Yeast |
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.041
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
2 |
0.041
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.041
|
Yeast |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.041
|
Yeast |
|
|
hormone transport
|
GO:0009914 |
121 |
0.041
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.040
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.040
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.040
|
Yeast |
|
|
glycogen metabolic process
|
GO:0005977 |
23 |
0.040
|
|
|
|
regulation of defense response
|
GO:0031347 |
68 |
0.040
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.039
|
Yeast |
|
|
neurological system process
|
GO:0050877 |
219 |
0.039
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
11 |
0.039
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.039
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.038
|
Yeast Mouse |
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.038
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
33 |
0.038
|
|
|
|
response to organophosphorus
|
GO:0046683 |
102 |
0.038
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
99 |
0.037
|
|
|
|
regulation of nitric oxide synthase activity
|
GO:0050999 |
8 |
0.037
|
|
|
|
dna damage response detection of dna damage
|
GO:0042769 |
2 |
0.037
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
35 |
0.037
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
1 |
0.037
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.037
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.037
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.037
|
|
|
|
response to bacterium
|
GO:0009617 |
200 |
0.037
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.036
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
10 |
0.036
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.036
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
9 |
0.036
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.036
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.036
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.036
|
|
|
|
chlorinated hydrocarbon metabolic process
|
GO:0042196 |
4 |
0.035
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.035
|
Yeast |
|
|
regulation of response to wounding
|
GO:1903034 |
69 |
0.035
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.035
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.035
|
|
|
|
male mating behavior
|
GO:0060179 |
3 |
0.035
|
|
|
|
single organism nuclear import
|
GO:1902593 |
35 |
0.035
|
|
|
|
atp catabolic process
|
GO:0006200 |
54 |
0.035
|
Yeast |
|
|
leukocyte mediated immunity
|
GO:0002443 |
28 |
0.034
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
30 |
0.034
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
48 |
0.034
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
16 |
0.034
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.034
|
Yeast |
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
2 |
0.034
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.034
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.034
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
58 |
0.034
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.034
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.034
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.033
|
Yeast |
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.033
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.033
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
52 |
0.033
|
Rat |
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.033
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.033
|
Yeast |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
19 |
0.033
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.032
|
Yeast |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.032
|
Yeast |
|
|
regulation of leukocyte activation
|
GO:0002694 |
45 |
0.032
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.032
|
Yeast |
|
|
icosanoid biosynthetic process
|
GO:0046456 |
18 |
0.032
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.032
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.032
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.032
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.031
|
|
|
|
reproductive system development
|
GO:0061458 |
128 |
0.031
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.031
|
Yeast |
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.031
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.031
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.031
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.031
|
|
|
|
mrna metabolic process
|
GO:0016071 |
20 |
0.031
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.031
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
23 |
0.030
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
48 |
0.030
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.030
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.030
|
|
|
|
aging
|
GO:0007568 |
241 |
0.030
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.030
|
Yeast Zebrafish |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
88 |
0.030
|
Yeast |
|
|
protein localization to nucleus
|
GO:0034504 |
39 |
0.029
|
|
|
|
hindbrain morphogenesis
|
GO:0021575 |
2 |
0.029
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.029
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
1 |
0.028
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.028
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
55 |
0.028
|
Yeast |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.028
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.028
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.028
|
|
|
|
protein targeting to mitochondrion
|
GO:0006626 |
7 |
0.028
|
Yeast |
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.028
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.027
|
|
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.027
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.027
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.027
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
39 |
0.027
|
Yeast |
|
|
muscle system process
|
GO:0003012 |
115 |
0.027
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.027
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
72 |
0.027
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.026
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
65 |
0.026
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
2 |
0.026
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.026
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.026
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.026
|
|
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.026
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.026
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
20 |
0.026
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.026
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.026
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.026
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.026
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.025
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
12 |
0.025
|
|
|
|
viral genome replication
|
GO:0019079 |
2 |
0.025
|
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.025
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
42 |
0.025
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.025
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.025
|
|
|
|
heart contraction
|
GO:0060047 |
57 |
0.025
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.025
|
|
|
|
dna metabolic process
|
GO:0006259 |
96 |
0.024
|
Yeast |
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.024
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
1 |
0.024
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.024
|
|
|
|
interleukin 10 production
|
GO:0032613 |
3 |
0.024
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.024
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
2 |
0.024
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.024
|
|
|
|
neuron projection guidance
|
GO:0097485 |
24 |
0.023
|
|
|
|
mast cell activation
|
GO:0045576 |
15 |
0.023
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
39 |
0.023
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.023
|
|
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.023
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.023
|
Yeast |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
2 |
0.023
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.023
|
Yeast Mouse |
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.022
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.022
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
83 |
0.022
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.022
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.022
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.022
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.022
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
3 |
0.022
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
25 |
0.022
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
77 |
0.022
|
|
|
|
response to antibiotic
|
GO:0046677 |
39 |
0.022
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.022
|
|
|
|
negative regulation of blood circulation
|
GO:1903523 |
20 |
0.021
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.021
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.021
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.021
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
4 |
0.021
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
3 |
0.021
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.021
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.021
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.021
|
|
|
|
muscle tissue development
|
GO:0060537 |
58 |
0.021
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
16 |
0.021
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.020
|
Zebrafish |
|
|
cellular response to unfolded protein
|
GO:0034620 |
2 |
0.020
|
|
|
|
nuclear transport
|
GO:0051169 |
49 |
0.020
|
|
|
|
glycogen biosynthetic process
|
GO:0005978 |
15 |
0.020
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
17 |
0.020
|
|
|
|
chromosome organization
|
GO:0051276 |
36 |
0.020
|
Yeast |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
62 |
0.020
|
|
|
|
protein processing
|
GO:0016485 |
68 |
0.020
|
|
|
|
urogenital system development
|
GO:0001655 |
78 |
0.020
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.020
|
|
|
|
ncrna processing
|
GO:0034470 |
3 |
0.020
|
|
|
|
dna recombination
|
GO:0006310 |
3 |
0.020
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
21 |
0.020
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.020
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
38 |
0.020
|
|
|
|
protein localization to organelle
|
GO:0033365 |
57 |
0.020
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
103 |
0.020
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.019
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
32 |
0.019
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.019
|
|
|
|
protein ubiquitination
|
GO:0016567 |
28 |
0.019
|
|
|
|
male gamete generation
|
GO:0048232 |
99 |
0.019
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
4 |
0.019
|
|
|
|
spermatogenesis
|
GO:0007283 |
99 |
0.019
|
|
|
|
neuron recognition
|
GO:0008038 |
9 |
0.019
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
70 |
0.019
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.019
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
59 |
0.019
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
37 |
0.018
|
|
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
4 |
0.018
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.018
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
60 |
0.018
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
73 |
0.018
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.018
|
|
