Rattus norvegicus

352 known processes

Map2k1

mitogen activated protein kinase kinase 1

(Aliases: Mek1)

Map2k1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.426
cellular component assembly GO:0022607 360 0.307
protein complex biogenesis GO:0070271 263 0.290
cellular response to oxygen containing compound GO:1901701 386 0.227
metal ion transport GO:0030001 289 0.207
intracellular transport GO:0046907 185 0.200
cellular response to stress GO:0033554 269 0.187
Human Yeast
carboxylic acid metabolic process GO:0019752 289 0.186
cellular component biogenesis GO:0044085 368 0.185
protein autophosphorylation GO:0046777 66 0.175
regulation of ion transport GO:0043269 245 0.171
macromolecular complex assembly GO:0065003 273 0.169
response to inorganic substance GO:0010035 377 0.166
endosome to lysosome transport GO:0008333 6 0.165
protein targeting GO:0006605 61 0.164
Yeast
macromolecule localization GO:0033036 252 0.155
Yeast
vesicle mediated transport GO:0016192 181 0.146
oxoacid metabolic process GO:0043436 290 0.136
positive regulation of protein modification process GO:0031401 142 0.135
response to peptide hormone GO:0043434 278 0.135
regulation of phosphorus metabolic process GO:0051174 349 0.132
protein localization to organelle GO:0033365 57 0.126
Yeast
macromolecular complex subunit organization GO:0043933 339 0.122
regulation of multicellular organismal development GO:2000026 376 0.122
regulation of protein metabolic process GO:0051246 289 0.121
positive regulation of signal transduction GO:0009967 175 0.121
cellular response to peptide GO:1901653 133 0.120
positive regulation of phosphate metabolic process GO:0045937 262 0.117
aging GO:0007568 241 0.117
Human Worm
nucleoside catabolic process GO:0009164 126 0.116
single organism intracellular transport GO:1902582 166 0.116
intracellular signal transduction GO:0035556 314 0.115
cellular macromolecule localization GO:0070727 122 0.113
Yeast
single organism catabolic process GO:0044712 283 0.111
protein complex assembly GO:0006461 263 0.110
regulation of signal transduction GO:0009966 318 0.105
positive regulation of protein transport GO:0051222 41 0.105
synaptic transmission GO:0007268 235 0.105
single organism cellular localization GO:1902580 102 0.100
inorganic ion transmembrane transport GO:0098660 229 0.100
negative regulation of cellular metabolic process GO:0031324 281 0.097
regulation of mapk cascade GO:0043408 116 0.095
cation transmembrane transport GO:0098655 263 0.095
regulation of cellular amino acid metabolic process GO:0006521 2 0.095
regulation of protein transport GO:0051223 68 0.095
regulation of ion transmembrane transport GO:0034765 121 0.094
positive regulation of signaling GO:0023056 270 0.094
establishment of protein localization to organelle GO:0072594 44 0.093
Yeast
protein complex subunit organization GO:0071822 302 0.093
organic substance catabolic process GO:1901575 316 0.091
anatomical structure morphogenesis GO:0009653 298 0.090
organelle organization GO:0006996 266 0.088
protein transport GO:0015031 132 0.087
Yeast
positive regulation of intracellular protein transport GO:0090316 20 0.086
secretion GO:0046903 307 0.085
positive regulation of transport GO:0051050 245 0.084
response to oxygen levels GO:0070482 265 0.084
cellular amino acid metabolic process GO:0006520 107 0.083
catabolic process GO:0009056 351 0.082
cellular response to endogenous stimulus GO:0071495 377 0.081
establishment of protein localization GO:0045184 141 0.080
Yeast
cellular response to nitrogen compound GO:1901699 210 0.080
protein phosphorylation GO:0006468 345 0.079
positive regulation of phosphorus metabolic process GO:0010562 262 0.079
negative regulation of response to stimulus GO:0048585 155 0.077
response to nutrient levels GO:0031667 370 0.076
response to wounding GO:0009611 254 0.076
regulation of synaptic transmission GO:0050804 141 0.076
regeneration GO:0031099 163 0.075
protein localization GO:0008104 191 0.075
Yeast
cellular catabolic process GO:0044248 295 0.075
response to peptide GO:1901652 292 0.074
negative regulation of phosphate metabolic process GO:0045936 80 0.074
regulation of cellular ketone metabolic process GO:0010565 27 0.073
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.073
cellular response to cytokine stimulus GO:0071345 127 0.073
amine metabolic process GO:0009308 38 0.073
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.073
negative regulation of molecular function GO:0044092 133 0.072
cellular ketone metabolic process GO:0042180 51 0.071
apoptotic process GO:0006915 381 0.071
Worm
response to nutrient GO:0007584 248 0.070
circulatory system process GO:0003013 183 0.070
regulation of protein import into nucleus GO:0042306 24 0.070
actin filament organization GO:0007015 42 0.069
Yeast
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.068
regulation of cellular localization GO:0060341 263 0.068
positive regulation of cell differentiation GO:0045597 217 0.068
Mouse
transmembrane transport GO:0055085 412 0.067
protein import into nucleus GO:0006606 35 0.067
Yeast
cellular response to insulin stimulus GO:0032869 81 0.066
regulation of neuron projection development GO:0010975 161 0.066
response to hypoxia GO:0001666 231 0.066
regulation of molecular function GO:0065009 398 0.065
regulation of cellular amine metabolic process GO:0033238 8 0.065
response to corticosteroid GO:0031960 235 0.065
negative regulation of cell communication GO:0010648 158 0.064
response to ethanol GO:0045471 162 0.064
developmental process involved in reproduction GO:0003006 159 0.064
Mouse Worm Fly
regulation of phosphorylation GO:0042325 248 0.062
cell cell signaling GO:0007267 335 0.062
positive regulation of cellular amine metabolic process GO:0033240 3 0.061
positive regulation of nervous system development GO:0051962 178 0.061
positive regulation of cell communication GO:0010647 271 0.061
regulation of cell morphogenesis GO:0022604 77 0.060
response to decreased oxygen levels GO:0036293 237 0.060
response to transition metal nanoparticle GO:1990267 122 0.059
regulation of anatomical structure morphogenesis GO:0022603 141 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.059
membrane organization GO:0061024 94 0.059
regulation of neurogenesis GO:0050767 247 0.058
mapk cascade GO:0000165 140 0.058
regulation of secretion GO:0051046 224 0.058
somatic stem cell division GO:0048103 2 0.058
actin filament based process GO:0030029 86 0.057
Yeast
cellular response to hormone stimulus GO:0032870 247 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.057
cardiovascular system development GO:0072358 134 0.056
Mouse
organic acid metabolic process GO:0006082 292 0.056
cell projection organization GO:0030030 302 0.055
response to cytokine GO:0034097 215 0.054
gastrulation GO:0007369 2 0.054
cellular response to peptide hormone stimulus GO:0071375 120 0.053
cellular response to molecule of bacterial origin GO:0071219 56 0.053
regulation of cell development GO:0060284 263 0.053
establishment of organelle localization GO:0051656 37 0.053
nitrogen compound transport GO:0071705 229 0.053
positive regulation of response to stimulus GO:0048584 285 0.053
positive regulation of developmental process GO:0051094 283 0.052
Mouse
divalent metal ion transport GO:0070838 132 0.052
regulation of phosphate metabolic process GO:0019220 349 0.052
protein import GO:0017038 37 0.052
Yeast
regulation of protein modification process GO:0031399 194 0.052
cellular protein localization GO:0034613 122 0.051
Yeast
ras protein signal transduction GO:0007265 29 0.051
regulation of cellular component organization GO:0051128 368 0.051
Yeast
regulation of secretion by cell GO:1903530 208 0.050
dephosphorylation GO:0016311 98 0.050
Mouse
response to molecule of bacterial origin GO:0002237 194 0.050
negative regulation of phosphorus metabolic process GO:0010563 80 0.049
divalent inorganic cation transport GO:0072511 134 0.049
regulation of hydrolase activity GO:0051336 143 0.049
neuron projection development GO:0031175 273 0.049
regulation of rna metabolic process GO:0051252 391 0.049
aromatic compound catabolic process GO:0019439 168 0.049
central nervous system development GO:0007417 311 0.048
response to insulin GO:0032868 133 0.048
single organism reproductive process GO:0044702 297 0.048
Mouse Worm Fly
jnk cascade GO:0007254 28 0.048
autophagy GO:0006914 19 0.048
Yeast
cellular amine metabolic process GO:0044106 38 0.048
nuclear transport GO:0051169 49 0.047
Yeast
regulation of system process GO:0044057 208 0.047
positive regulation of mapk cascade GO:0043410 92 0.047
regulation of cellular component biogenesis GO:0044087 86 0.046
endomembrane system organization GO:0010256 48 0.046
protein oligomerization GO:0051259 191 0.046
positive regulation of secretion GO:0051047 140 0.046
nucleocytoplasmic transport GO:0006913 48 0.045
Yeast
regulation of protein phosphorylation GO:0001932 183 0.045
regulation of intracellular signal transduction GO:1902531 218 0.045
circulatory system development GO:0072359 134 0.045
Mouse
chromosome segregation GO:0007059 2 0.045
calcium ion transport GO:0006816 131 0.044
regulation of cell projection organization GO:0031344 175 0.044
negative regulation of metabolic process GO:0009892 331 0.044
regulation of metal ion transport GO:0010959 118 0.044
ion transmembrane transport GO:0034220 365 0.044
neuron differentiation GO:0030182 368 0.044
regulation of catalytic activity GO:0050790 304 0.043
response to lipopolysaccharide GO:0032496 191 0.043
tissue development GO:0009888 252 0.043
Mouse Fly
positive regulation of protein polymerization GO:0032273 10 0.043
regulation of protein complex assembly GO:0043254 33 0.043
regulation of cell differentiation GO:0045595 320 0.043
Mouse
negative regulation of cell differentiation GO:0045596 99 0.043
positive regulation of apoptotic process GO:0043065 154 0.042
nucleoside monophosphate metabolic process GO:0009123 93 0.042
cardiac chamber development GO:0003205 1 0.042
regulation of nervous system development GO:0051960 264 0.042
positive regulation of actin filament polymerization GO:0030838 5 0.042
response to carbohydrate GO:0009743 183 0.042
positive regulation of phosphoprotein phosphatase activity GO:0032516 3 0.042
positive regulation of programmed cell death GO:0043068 157 0.042
reactive oxygen species biosynthetic process GO:1903409 8 0.041
organic hydroxy compound transport GO:0015850 77 0.041
single organism nuclear import GO:1902593 35 0.041
Yeast
cellular response to organonitrogen compound GO:0071417 197 0.041
neuron apoptotic process GO:0051402 88 0.041
organophosphate metabolic process GO:0019637 370 0.040
regulation of establishment of protein localization GO:0070201 69 0.039
small gtpase mediated signal transduction GO:0007264 36 0.039
regulation of anatomical structure size GO:0090066 135 0.038
regulation of catecholamine secretion GO:0050433 32 0.038
regulation of neuron differentiation GO:0045664 208 0.038
positive regulation of cell migration GO:0030335 96 0.038
positive regulation of cellular component organization GO:0051130 200 0.038
negative regulation of cell death GO:0060548 229 0.037
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.037
cellular response to alcohol GO:0097306 87 0.037
protein dephosphorylation GO:0006470 38 0.037
Mouse
exocytosis GO:0006887 60 0.037
halogenated hydrocarbon metabolic process GO:0042197 4 0.036
enzyme linked receptor protein signaling pathway GO:0007167 116 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.036
signal transduction by phosphorylation GO:0023014 144 0.036
gland development GO:0048732 155 0.036
g protein coupled receptor signaling pathway GO:0007186 242 0.036
Yeast
response to toxic substance GO:0009636 133 0.036
arp2 3 complex mediated actin nucleation GO:0034314 2 0.035
regulation of synaptic plasticity GO:0048167 70 0.035
calcium ion transmembrane transport GO:0070588 70 0.035
response to extracellular stimulus GO:0009991 380 0.034
monocarboxylic acid metabolic process GO:0032787 152 0.033
peptidyl amino acid modification GO:0018193 126 0.033
negative regulation of cell development GO:0010721 82 0.033
response to hexose GO:0009746 144 0.033
sodium ion transport GO:0006814 82 0.032
response to glucocorticoid GO:0051384 223 0.032
cellular component morphogenesis GO:0032989 155 0.032
negative regulation of transport GO:0051051 136 0.032
programmed cell death GO:0012501 392 0.032
Worm
rna metabolic process GO:0016070 406 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
response to estrogen GO:0043627 232 0.031
proteolysis GO:0006508 175 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
regulation of response to external stimulus GO:0032101 106 0.030
nucleic acid templated transcription GO:0097659 379 0.030
regulation of programmed cell death GO:0043067 341 0.030
purine containing compound metabolic process GO:0072521 253 0.030
homeostatic process GO:0042592 331 0.030
defense response GO:0006952 194 0.029
neuron death GO:0070997 127 0.029
positive regulation of cell projection organization GO:0031346 111 0.029
behavior GO:0007610 205 0.029
cellular nitrogen compound catabolic process GO:0044270 163 0.029
neuron development GO:0048666 286 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
reactive nitrogen species metabolic process GO:2001057 1 0.029
multi organism reproductive process GO:0044703 262 0.029
Yeast Fly
regulation of cellular protein metabolic process GO:0032268 267 0.028
cell migration GO:0016477 197 0.028
negative regulation of signal transduction GO:0009968 83 0.028
sexual reproduction GO:0019953 148 0.028
Yeast Fly
positive regulation of cell development GO:0010720 176 0.028
cytoplasmic transport GO:0016482 115 0.028
Yeast
multicellular organism reproduction GO:0032504 233 0.028
Fly
nuclear import GO:0051170 35 0.028
Yeast
positive regulation of intracellular signal transduction GO:1902533 138 0.028
regulation of cellular component size GO:0032535 51 0.028
regulation of locomotion GO:0040012 148 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
regulation of dopamine secretion GO:0014059 15 0.027
inorganic cation transmembrane transport GO:0098662 202 0.027
purine nucleoside monophosphate metabolic process GO:0009126 84 0.027
blood circulation GO:0008015 183 0.027
secretion by cell GO:0032940 248 0.027
negative regulation of apoptotic process GO:0043066 181 0.026
cell motility GO:0048870 202 0.026
growth GO:0040007 165 0.026
Yeast
regulation of stress activated mapk cascade GO:0032872 23 0.026
regulation of response to wounding GO:1903034 69 0.026
neuron projection morphogenesis GO:0048812 122 0.026
regulation of nucleocytoplasmic transport GO:0046822 28 0.026
negative regulation of protein phosphorylation GO:0001933 44 0.026
negative regulation of signaling GO:0023057 157 0.025
catecholamine secretion GO:0050432 33 0.025
regulation of ion transmembrane transporter activity GO:0032412 48 0.025
single organism membrane organization GO:0044802 74 0.025
protein polymerization GO:0051258 22 0.025
negative regulation of transporter activity GO:0032410 13 0.025
cellular response to organic cyclic compound GO:0071407 202 0.025
regulation of protein phosphatase type 2a activity GO:0034047 2 0.025
sensory perception of pain GO:0019233 73 0.025
regulation of calcium ion transport GO:0051924 77 0.025
cell growth GO:0016049 104 0.025
Yeast
regulation of calcium ion transmembrane transporter activity GO:1901019 17 0.024
regulation of actin filament based process GO:0032970 42 0.024
heterocycle catabolic process GO:0046700 167 0.024
positive regulation of cytoskeleton organization GO:0051495 26 0.024
positive regulation of secretion by cell GO:1903532 128 0.024
protein targeting to nucleus GO:0044744 35 0.024
Yeast
negative regulation of phosphorylation GO:0042326 57 0.024
lysosomal transport GO:0007041 8 0.024
reactive oxygen species metabolic process GO:0072593 37 0.024
regulation of cell motility GO:2000145 131 0.024
regulation of protein polymerization GO:0032271 19 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
cell type specific apoptotic process GO:0097285 134 0.024
response to bacterium GO:0009617 200 0.024
regulation of protein kinase activity GO:0045859 105 0.023
muscle system process GO:0003012 115 0.023
ribonucleoside monophosphate metabolic process GO:0009161 88 0.023
macromolecule catabolic process GO:0009057 58 0.023
Worm
positive regulation of phosphorylation GO:0042327 177 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
Fly
positive regulation of odontogenesis of dentin containing tooth GO:0042488 1 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
neuronal stem cell division GO:0036445 1 0.022
protein ubiquitination GO:0016567 28 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
positive regulation of lamellipodium assembly GO:0010592 4 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
mammary gland epithelium development GO:0061180 1 0.022
regulation of response to stress GO:0080134 126 0.022
Yeast
carbohydrate derivative metabolic process GO:1901135 346 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
endocytosis GO:0006897 84 0.022
transcription dna templated GO:0006351 377 0.022
regulation of hormone levels GO:0010817 187 0.022
regulation of map kinase activity GO:0043405 53 0.022
rna biosynthetic process GO:0032774 380 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
cell morphogenesis GO:0000902 142 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
organelle localization GO:0051640 55 0.022
regulation of cytoskeleton organization GO:0051493 49 0.022
protein homooligomerization GO:0051260 91 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.021
positive regulation of synaptic transmission GO:0050806 62 0.021
regulation of intracellular protein transport GO:0033157 34 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
immune system process GO:0002376 204 0.021
Fly
intracellular protein transport GO:0006886 79 0.021
Yeast
purine containing compound catabolic process GO:0072523 138 0.021
centrosome organization GO:0051297 1 0.021
regulation of actin nucleation GO:0051125 2 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
regulation of apoptotic process GO:0042981 335 0.020
smad protein complex assembly GO:0007183 1 0.020
nucleotide metabolic process GO:0009117 279 0.020
regulation of cell proliferation GO:0042127 359 0.020
Human
positive regulation of ion transport GO:0043270 94 0.020
axon development GO:0061564 96 0.020
dendrite development GO:0016358 72 0.020
response to purine containing compound GO:0014074 126 0.020
cellular cation homeostasis GO:0030003 180 0.020
regulation of membrane potential GO:0042391 110 0.020
endosomal transport GO:0016197 14 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
regulation of cellular response to stress GO:0080135 49 0.020
Yeast
cofactor biosynthetic process GO:0051188 28 0.020
response to antibiotic GO:0046677 39 0.020
early endosome to late endosome transport GO:0045022 2 0.020
wound healing GO:0042060 122 0.019
cation homeostasis GO:0055080 195 0.019
embryo development GO:0009790 49 0.019
Mouse Worm Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
adult locomotory behavior GO:0008344 4 0.019
brain development GO:0007420 247 0.019
response to glucose GO:0009749 136 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
regulation of protein localization GO:0032880 81 0.019
peptide transport GO:0015833 97 0.019
biological adhesion GO:0022610 110 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
regulation of calcium ion transmembrane transport GO:1903169 18 0.019
response to metal ion GO:0010038 253 0.019
protein catabolic process GO:0030163 30 0.019
Worm
regulation of kinase activity GO:0043549 117 0.019
nucleoside monophosphate catabolic process GO:0009125 56 0.019
regulation of transcription dna templated GO:0006355 374 0.018
monoamine transport GO:0015844 43 0.018
dopamine secretion GO:0014046 15 0.018
response to growth factor GO:0070848 189 0.018
regulation of protein targeting GO:1903533 28 0.018
single organism behavior GO:0044708 130 0.018
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.018
regulation of vasculature development GO:1901342 44 0.018
reproductive process GO:0022414 372 0.018
Yeast Mouse Worm Fly
stress activated mapk cascade GO:0051403 35 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
regulation of postsynaptic membrane potential GO:0060078 25 0.018
regulation of blood vessel size GO:0050880 89 0.018
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.018
dopamine transport GO:0015872 18 0.018
vasculature development GO:0001944 70 0.018
Mouse
inflammatory response GO:0006954 150 0.017
regulation of dendrite development GO:0050773 59 0.017
neurological system process GO:0050877 219 0.017
regulation of tube size GO:0035150 89 0.017
positive regulation of molecular function GO:0044093 230 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
response to external biotic stimulus GO:0043207 221 0.017
response to activity GO:0014823 73 0.017
protein heterooligomerization GO:0051291 89 0.017
receptor mediated endocytosis GO:0006898 42 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
regulation of reactive oxygen species metabolic process GO:2000377 26 0.017
chlorinated hydrocarbon metabolic process GO:0042196 4 0.017
asymmetric stem cell division GO:0098722 2 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.016
negative regulation of developmental process GO:0051093 125 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
regulation of transferase activity GO:0051338 123 0.016
response to acid chemical GO:0001101 222 0.016
cellular homeostasis GO:0019725 252 0.016
cellular response to lipid GO:0071396 201 0.016
cellular chemical homeostasis GO:0055082 247 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
response to other organism GO:0051707 220 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
positive regulation of protein dephosphorylation GO:0035307 4 0.016
establishment or maintenance of cell polarity GO:0007163 8 0.016
peptidyl serine modification GO:0018209 34 0.016
cellular response to metal ion GO:0071248 55 0.016
gamete generation GO:0007276 124 0.016
Fly
nucleoside triphosphate metabolic process GO:0009141 144 0.015
leukocyte activation involved in immune response GO:0002366 16 0.015
epithelium development GO:0060429 96 0.015
Mouse Fly
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.015
catecholamine transport GO:0051937 37 0.015
negative regulation of intracellular signal transduction GO:1902532 38 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
regulation of actin cytoskeleton organization GO:0032956 30 0.015
locomotion GO:0040011 237 0.015
regulation of actin filament length GO:0030832 12 0.015
development of primary sexual characteristics GO:0045137 107 0.015
Worm
positive regulation of cell proliferation GO:0008284 249 0.015
alpha amino acid biosynthetic process GO:1901607 23 0.015
regulation of cell cycle GO:0051726 73 0.015
Human
response to monosaccharide GO:0034284 159 0.015
cellular macromolecule catabolic process GO:0044265 29 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
positive regulation of cell death GO:0010942 184 0.015
regulation of amine transport GO:0051952 54 0.014
negative regulation of protein modification process GO:0031400 52 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
regulation of intracellular transport GO:0032386 65 0.014
negative regulation of nervous system development GO:0051961 79 0.014
oxidation reduction process GO:0055114 304 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
peptidyl serine phosphorylation GO:0018105 33 0.014
response to alkaloid GO:0043279 132 0.014
regulation of stem cell differentiation GO:2000736 2 0.014
digestive system development GO:0055123 41 0.014
regulation of catabolic process GO:0009894 113 0.014
response to starvation GO:0042594 59 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.014
Fly
mesoderm development GO:0007498 2 0.014
positive regulation of transcription factor import into nucleus GO:0042993 4 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
positive regulation of cytoplasmic transport GO:1903651 32 0.014
positive regulation of organelle organization GO:0010638 48 0.014
response to heat GO:0009408 60 0.014
Yeast
regulation of protein secretion GO:0050708 28 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
regulation of cell migration GO:0030334 128 0.014
embryonic pattern specification GO:0009880 1 0.014
Fly
negative regulation of catalytic activity GO:0043086 103 0.014
heart contraction GO:0060047 57 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
gtp catabolic process GO:0006184 71 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
Human
negative regulation of gene expression GO:0010629 199 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
cellular component movement GO:0006928 248 0.013
negative regulation of ion transport GO:0043271 51 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to biotic stimulus GO:0009607 226 0.013
nucleoside metabolic process GO:0009116 179 0.013
hormone secretion GO:0046879 115 0.013
single organism biosynthetic process GO:0044711 342 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.013
reproduction GO:0000003 245 0.013
Yeast Worm Fly
cytoskeleton organization GO:0007010 111 0.013
Yeast
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.013
embryonic axis specification GO:0000578 1 0.012
Fly
response to retinoic acid GO:0032526 63 0.012
regulation of immune system process GO:0002682 123 0.012
negative regulation of stress activated mapk cascade GO:0032873 4 0.012
response to camp GO:0051591 91 0.012
bmp signaling pathway GO:0030509 4 0.012
apoptotic signaling pathway GO:0097190 27 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
sex differentiation GO:0007548 113 0.012
Worm
cellular metal ion homeostasis GO:0006875 172 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
protein modification by small protein conjugation GO:0032446 31 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
response to axon injury GO:0048678 59 0.012
response to oxidative stress GO:0006979 186 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
membrane fusion GO:0061025 26 0.012
response to reactive oxygen species GO:0000302 120 0.012
response to ketone GO:1901654 182 0.012
actin nucleation GO:0045010 2 0.012
motor neuron axon guidance GO:0008045 1 0.012

Map2k1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org